Search Results - Scheer, Frithjof

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  1. 1
    Which Properties Allow Ligands to Open and Bind to the Transient Binding Pocket of Human Aldose Reductase?

    Which Properties Allow Ligands to Open and Bind to the Transient Binding Pocket of Human Aldose Reductase? by Sandner, Anna, Ngo, Khang, Sager, Christoph P, Scheer, Frithjof, Daude, Michael, Diederich, Wibke E, Heine, Andreas, Klebe, Gerhard

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  2. 2
    Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) β/δ Inverse Agonists with Prolonged Cellular Activity

    Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) β/δ Inverse Agonists with Prolonged Cellular Activity by Toth, Philipp M., Lieber, Sonja, Scheer, Frithjof M., Schumann, Tim, Schober, Yvonne, Nockher, Wolfgang A., Adhikary, Till, Müller-Brüsselbach, Sabine, Müller, Rolf, Diederich, Wibke E.

    Published in ChemMedChem
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  3. 3
    Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) [beta]/[delta] Inverse Agonists with Prolonged Cellular Activity

    Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) [beta]/[delta] Inverse Agonists with Prolonged Cellular Activity by Toth, Philipp M, Lieber, Sonja, Scheer, Frithjof M, Schumann, Tim, Schober, Yvonne, Nockher, Wolfgang A, Adhikary, Till, Muller-Brusselbach, Sabine, Muller, Rolf, Diederich, Wibke E

    Published in ChemMedChem
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  4. 4
    Price for Opening the Transient Specificity Pocket in Human Aldose Reductase upon Ligand Binding: Structural, Thermodynamic, Kinetic, and Computational Analysis

    Price for Opening the Transient Specificity Pocket in Human Aldose Reductase upon Ligand Binding: Structural, Thermodynamic, Kinetic, and Computational Analysis by Rechlin, Chris, Scheer, Frithjof, Terwesten, Felix, Wulsdorf, Tobias, Pol, Ewa, Fridh, Veronica, Toth, Philipp, Diederich, Wibke E, Heine, Andreas, Klebe, Gerhard

    Published in ACS chemical biology
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  5. 5
    (Z)-2-(2-Bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): An Orally Bioavailable PPARβ/δ-Selective Ligand with Inverse Agonistic Properties

    (Z)-2-(2-Bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): An Orally Bioavailable PPARβ/δ-Selective Ligand with Inverse Agonistic Properties by Lieber, Sonja, Scheer, Frithjof, Meissner, Wolfgang, Naruhn, Simone, Adhikary, Till, Müller-Brüsselbach, Sabine, Diederich, Wibke E, Müller, Rolf

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  6. 6
    The inverse agonist DG172 triggers a PPARβ/δ-independent myeloid lineage shift and promotes GM-CSF/IL-4-induced dendritic cell differentiation

    The inverse agonist DG172 triggers a PPARβ/δ-independent myeloid lineage shift and promotes GM-CSF/IL-4-induced dendritic cell differentiation by Lieber, Sonja, Scheer, Frithjof, Finkernagel, Florian, Meissner, Wolfgang, Giehl, Gavin, Brendel, Cornelia, Diederich, Wibke E, Müller-Brüsselbach, Sabine, Müller, Rolf

    Published in Molecular pharmacology
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  7. 7
    Cover Picture: Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) β/δ Inverse Agonists with Prolonged Cellular Activity (ChemMedChem 5/2016)

    Cover Picture: Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) β/δ Inverse Agonists with Prolonged Cellular Activity (ChemMedChem 5/2016) by Toth, Philipp M., Lieber, Sonja, Scheer, Frithjof M., Schumann, Tim, Schober, Yvonne, Nockher, Wolfgang A., Adhikary, Till, Müller-Brüsselbach, Sabine, Müller, Rolf, Diederich, Wibke E.

    Published in ChemMedChem
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  8. 8
    Cover Picture: Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) [beta]/[delta] Inverse Agonists with Prolonged Cellular Activity

    Cover Picture: Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) [beta]/[delta] Inverse Agonists with Prolonged Cellular Activity by Toth, Philipp M, Lieber, Sonja, Scheer, Frithjof M, Schumann, Tim, Schober, Yvonne, Nockher, Wolfgang A, Adhikary, Till, Muller-Brusselbach, Sabine, Muller, Rolf, Diederich, Wibke E

    Published in ChemMedChem
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