Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum by Kümpornsin, Krittikorn, Kochakarn, Theerarat, Yeo, Tomas, Okombo, John, Luth, Madeline R., Hoshizaki, Johanna, Rawat, Mukul, Pearson, Richard D., Schindler, Kyra A., Mok, Sachel, Park, Heekuk, Uhlemann, Anne-Catrin, Jana, Gouranga P., Maity, Bikash C., Laleu, Benoît, Chenu, Elodie, Duffy, James, Moliner Cubel, Sonia, Franco, Virginia, Gomez-Lorenzo, Maria G., Gamo, Francisco Javier, Winzeler, Elizabeth A., Fidock, David A., Chookajorn, Thanat, Lee, Marcus C. S.

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Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered Plasmodium falciparum physiology by Hagenah, Laura M, Dhingra, Satish K, Small-Saunders, Jennifer L, Qahash, Tarrick, Willems, Andreas, Schindler, Kyra A, Rangel, Gabriel W, Gil-Iturbe, Eva, Kim, Jonathan, Akhundova, Emiliya, Yeo, Tomas, Okombo, John, Mancia, Filippo, Quick, Matthias, Roepe, Paul D, Llinás, Manuel, Fidock, David A

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Hoxa5 Activity Across the Lateral Somitic Frontier Regulates Development of the Mouse Sternum by Mitchel, Kira, Bergmann, Jenna M, Brent, Ava E, Finkelstein, Tova M, Schindler, Kyra A, Holzman, Miriam A, Jeannotte, Lucie, Mansfield, Jennifer H

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HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation by Holzman, Miriam A, Ryckman, Abigail, Finkelstein, Tova M, Landry-Truchon, Kim, Schindler, Kyra A, Bergmann, Jenna M, Jeannotte, Lucie, Mansfield, Jennifer H

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Plasmodium falciparum African PfCRT Mutant Isoforms Conducive to Piperaquine Resistance are Infrequent and Impart a Major Fitness Cost by Hagenah, Laura M, Yeo, Tomas, Schindler, Kyra A, Jeon, Jin H, Bloxham, Talia S, Small-Saunders, Jennifer L, Mok, Sachel, Fidock, David A

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Optimization of 2,3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting PfATP4 by Ashton, Trent D., Dans, Madeline G., Favuzza, Paola, Ngo, Anna, Lehane, Adele M., Zhang, Xinxin, Qiu, Deyun, Chandra Maity, Bikash, De, Nirupam, Schindler, Kyra A., Yeo, Tomas, Park, Heekuk, Uhlemann, Anne-Catrin, Churchyard, Alisje, Baum, Jake, Fidock, David A., Jarman, Kate E., Lowes, Kym N., Baud, Delphine, Brand, Stephen, Jackson, Paul F., Cowman, Alan F., Sleebs, Brad E.

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Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases by Wang, Lushun, Bohmer, Monica J., Wang, Jinhua, Nardella, Flore, Calla, Jaeson, Laureano De Souza, Mariana, Schindler, Kyra A., Montejo, Lukas, Mittal, Nimisha, Rocamora, Frances, Treat, Mayland, Charlton, Jordan T., Tumwebaze, Patrick K., Rosenthal, Philip J., Cooper, Roland A., Chakrabarti, Ratna, Winzeler, Elizabeth A., Chakrabarti, Debopam, Gray, Nathanael S.

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Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series by Palmer, Michael J, Deng, Xiaoyi, Watts, Shawn, Krilov, Goran, Gerasyuto, Aleksey, Kokkonda, Sreekanth, El Mazouni, Farah, White, John, White, Karen L, Striepen, Josefine, Bath, Jade, Schindler, Kyra A, Yeo, Tomas, Shackleford, David M, Mok, Sachel, Deni, Ioanna, Lawong, Aloysus, Huang, Ann, Chen, Gong, Wang, Wen, Jayaseelan, Jaya, Katneni, Kasiram, Patil, Rahul, Saunders, Jessica, Shahi, Shatrughan P, Chittimalla, Rajesh, Angulo-Barturen, Iñigo, Jiménez-Díaz, María Belén, Wittlin, Sergio, Tumwebaze, Patrick K, Rosenthal, Philip J, Cooper, Roland A, Aguiar, Anna Caroline Campos, Guido, Rafael V. C, Pereira, Dhelio B, Mittal, Nimisha, Winzeler, Elizabeth A, Tomchick, Diana R, Laleu, Benoît, Burrows, Jeremy N, Rathod, Pradipsinh K, Fidock, David A, Charman, Susan A, Phillips, Margaret A

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Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation by Bopp, Selina, Pasaje, Charisse Flerida A., Summers, Robert L., Magistrado-Coxen, Pamela, Schindler, Kyra A., Corpas-Lopez, Victoriano, Yeo, Tomas, Mok, Sachel, Dey, Sumanta, Smick, Sebastian, Nasamu, Armiyaw S., Demas, Allison R., Milne, Rachel, Wiedemar, Natalie, Corey, Victoria, Gomez-Lorenzo, Maria De Gracia, Franco, Virginia, Early, Angela M., Lukens, Amanda K., Milner, Danny, Furtado, Jeremy, Gamo, Francisco-Javier, Winzeler, Elizabeth A., Volkman, Sarah K., Duffey, Maëlle, Laleu, Benoît, Fidock, David A., Wyllie, Susan, Niles, Jacquin C., Wirth, Dyann F.

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Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission by Gomez-Gonzalez, Paula-Josefina, Gupta, Antima, Drought, Laura G, Patel, Avnish, Okombo, John, van der Watt, Mariëtte, Walker-Gray, Ryan, Schindler, Kyra A, Burkhard, Anna Y, Yeo, Tomas, Narwal, Sunil K, Bloxham, Talia S, Flueck, Christian, Walker, Eloise M, Rey, Joshua A, Fairhurst, Kate J, Reader, Janette, Park, Heekuk, Pollard, Harry G, Stewart, Lindsay B, Brandner-Garrod, Luke, Kristan, Mojca, Sterk, Geert-Jan, van Nuland, Youri M, Manko, Emilia, van Schalkwyk, Donelly A, Zheng, Yang, Leurs, Rob, Dechering, Koen J, Aguiar, Anna Caroline C, Guido, Rafael V C, Pereira, Dhelio B, Tumwebaze, Patrick K, Nosbya, Samuel L, Rosenthal, Philip J, Cooper, Roland A, Palmer, Mike, Parkinson, Tanya, Burrows, Jeremy N, Uhlemann, Anne-Catrin, Birkholtz, Lyn-Marié, Small-Saunders, Jennifer L, Duffy, James, Fidock, David A, Brown, Alan, Gardner, Mark, Baker, David A

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Abstract P1-05-01: The tumor immune microenvironment and HER2 landscape of high-risk ductal carcinoma in situ: The DEFENSE study by Glencer, Alexa, Borowsky, Alexander, Mori, Hidetoshi, Campbell, Michael, Harismendy, Olivier, Stein, Janet, Ghule, Prachi, Evans, Mark, West, Robert, Hirst, Gillian, Schindler, Nicole, Miller, Phoebe, Lee, Kyra, Weaver, Donald, Esserman, Laura

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