Search Results - Schittenhelm, Marcus M.

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  1. 1
    Evaluation of apoptosis stimulating protein of TP53-1 (ASPP1/PPP1R13B) to predict therapy resistance and overall survival in acute myeloid leukemia (AML)

    Evaluation of apoptosis stimulating protein of TP53-1 (ASPP1/PPP1R13B) to predict therapy resistance and overall survival in acute myeloid leukemia (AML) by Schittenhelm, Marcus M., Kaiser, Max, Győrffy, Balázs, Kampa-Schittenhelm, Kerstin M.

    Published in Cell death & disease
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  2. 2
    Alternative splicing of Apoptosis Stimulating Protein of TP53-2 (ASPP2) results in an oncogenic isoform promoting migration and therapy resistance in soft tissue sarcoma (STS)

    Alternative splicing of Apoptosis Stimulating Protein of TP53-2 (ASPP2) results in an oncogenic isoform promoting migration and therapy resistance in soft tissue sarcoma (STS) by Tsintari, Vasileia, Walter, Bianca, Fend, Falko, Overkamp, Mathis, Rothermundt, Christian, Lopez, Charles D., Schittenhelm, Marcus M., Kampa-Schittenhelm, Kerstin M.

    Published in BMC cancer
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  3. 3
    Impact of TP53 Mutation Status in Elderly AML Patients When Adding All-Trans Retinoic Acid or Valproic Acid to Decitabine

    Impact of TP53 Mutation Status in Elderly AML Patients When Adding All-Trans Retinoic Acid or Valproic Acid to Decitabine by Bresser, Helena, Schmoor, Claudia, Grishina, Olga, Pfeifer, Dietmar, Thomas, Johanna, Rehman, Usama-Ur, Crysandt, Martina, Jost, Edgar, Thol, Felicitas, Heuser, Michael, Götze, Katharina S, Schlenk, Richard F, Salih, Helmut R, Schittenhelm, Marcus M, Heil, Gerhard, Schwaenen, Carsten, Müller-Tidow, Carsten, Brugger, Wolfram, Kündgen, Andrea, de Wit, Maike, Giagounidis, Aristoteles, Scholl, Sebastian, Neubauer, Andreas, Krauter, Jürgen, Bug, Gesine, May, Annette M, Wäsch, Ralph, Duyster, Justus, Döhner, Konstanze, Ganser, Arnold, Döhner, Hartmut, Hackanson, Björn, Becker, Heiko, Lübbert, Michael

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  4. 4
    Attenuated expression of apoptosis stimulating protein of p53-2 (ASPP2) in human acute leukemia is associated with therapy failure

    Attenuated expression of apoptosis stimulating protein of p53-2 (ASPP2) in human acute leukemia is associated with therapy failure by Schittenhelm, Marcus M, Illing, Barbara, Ahmut, Figen, Rasp, Katharina Henriette, Blumenstock, Gunnar, Döhner, Konstanze, Lopez, Charles D, Kampa-Schittenhelm, Kerstin M

    Published in PloS one
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  5. 5
    Identification of Driver and Passenger Mutations of FLT3 by High-Throughput DNA Sequence Analysis and Functional Assessment of Candidate Alleles

    Identification of Driver and Passenger Mutations of FLT3 by High-Throughput DNA Sequence Analysis and Functional Assessment of Candidate Alleles by Fröhling, Stefan, Scholl, Claudia, Levine, Ross L., Loriaux, Marc, Boggon, Titus J., Bernard, Olivier A., Berger, Roland, Döhner, Hartmut, Döhner, Konstanze, Ebert, Benjamin L., Teckie, Sewit, Golub, Todd R., Jiang, Jingrui, Schittenhelm, Marcus M., Lee, Benjamin H., Griffin, James D., Stone, Richard M., Heinrich, Michael C., Deininger, Michael W., Druker, Brian J., Gilliland, D. Gary

    Published in Cancer cell
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  6. 6
    ASPP2κ Is Expressed In Human Colorectal Carcinoma And Promotes Chemotherapy Resistance And Tumorigenesis

    ASPP2κ Is Expressed In Human Colorectal Carcinoma And Promotes Chemotherapy Resistance And Tumorigenesis by Rieger, Ingmar, Tsintari, Vasileia, Overkamp, Mathis, Fend, Falko, Lopez, Charles D., Schittenhelm, Marcus M., Kampa-Schittenhelm, Kerstin M.

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  7. 7
    The FLT3 inhibitor tandutinib (formerly MLN518) has sequence-independent synergistic effects with cytarabine and daunorubicin

    The FLT3 inhibitor tandutinib (formerly MLN518) has sequence-independent synergistic effects with cytarabine and daunorubicin by Schittenhelm, Marcus M., Kampa, Kerstin M., Yee, Kevin W. H., Heinrich, Michael C.

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  8. 8
    Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies

    Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human mal... by SCHITTENHELM, Marcus M, SHIRAGA, Sharon, SCHROEDER, Arin, CORBIN, Amie S, GRIFFITH, Diana, LEE, Francis Y, BOKEMEYER, Carsten, DEININGER, Michael W. N, DRUKER, Brian J, HEINRICH, Michael C

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  9. 9
    Dasatinib overrides the differentiation blockage in a patient with mutant- KIT D816V positive CBFβ-MYH11 leukemia

    Dasatinib overrides the differentiation blockage in a patient with mutant- KIT D816V positive CBFβ-MYH11 leukemia by Kampa-Schittenhelm, Kerstin M, Vogel, Wichard, Bonzheim, Irina, Fend, Falko, Horger, Marius, Kanz, Lothar, Soekler, Martin, Schittenhelm, Marcus M

    Published in Oncotarget
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  10. 10
    Molecular determinants of response to matuzumab in combination with paclitaxel for patients with advanced non-small cell lung cancer

    Molecular determinants of response to matuzumab in combination with paclitaxel for patients with advanced non-small cell lung cancer by Schittenhelm, Marcus M, Kollmannsberger, Christian, Oechsle, Karin, Harlow, Amy, Morich, Jason, Honecker, Friedemann, Kurek, Raffael, Störkel, Stephan, Kanz, Lothar, Corless, Christopher L, Wong, Kwok-Kin, Bokemeyer, Carsten, Heinrich, Michael C

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  11. 11
    Attenuation of the Apoptosis Stimulating Protein of TP53-1 (ASPP1) Is a Predictive Marker for Therapy Resistance and Overall Survival in Acute Myeloid Leukemia (AML)

    Attenuation of the Apoptosis Stimulating Protein of TP53-1 (ASPP1) Is a Predictive Marker for Therapy Resistance and Overall Survival in Acute Myeloid Leukemia (AML) by Schittenhelm, Marcus M., Kaiser, Max, Tsintari, Vasileia, Blumenstock, Gunnar, Györffy, Balazs, Kampa-Schittenhelm, Kerstin Maria

    Published in Blood
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  12. 12
    ASPP2 k, a Dominant-Negative Splicing Variant of the Apoptosis-Stimulating Protein of p53-2 (ASPP2), Modulates Treatment Response Towards BCL-Signaling Inhibitors in Acute Myeloid Leukemia

    ASPP2 k, a Dominant-Negative Splicing Variant of the Apoptosis-Stimulating Protein of p53-2 (ASPP2), Modulates Treatment Response Towards BCL-Signaling Inhibitors in Acute Myeloid... by Schittenhelm, Marcus M., Tsintari, Vasileia, Fröhlich, Rebecca, Kampa-Schittenhelm, Kerstin Maria

    Published in Blood
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  13. 13
    Alternative splicing of Apoptosis Stimulating Protein of TP53-2

    Alternative splicing of Apoptosis Stimulating Protein of TP53-2 by Tsintari, Vasileia, Walter, Bianca, Fend, Falko, Overkamp, Mathis, Rothermundt, Christian, Lopez, Charles D, Schittenhelm, Marcus M, Kampa-Schittenhelm, Kerstin M

    Published in BMC cancer
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  14. 14
    Attenuation of Apoptosis Stimulating Protein of p53-1 (ASPP1) Associates with Therapy Failure in Acute Myeloid Leukemia (AML)

    Attenuation of Apoptosis Stimulating Protein of p53-1 (ASPP1) Associates with Therapy Failure in Acute Myeloid Leukemia (AML) by Schittenhelm, Marcus M., Kaiser, Max, Blumenstock, Gunnar, Kampa-Schittenhelm, Kerstin Maria

    Published in Blood
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  15. 15
    Oncogenic Splicing of the Apoptosis-Stimulating Protein of p53-2 (ASPP2) Is an Initiating Step in Leukemogenesis Facilitating Acquisition of Structural Genomic Mutations

    Oncogenic Splicing of the Apoptosis-Stimulating Protein of p53-2 (ASPP2) Is an Initiating Step in Leukemogenesis Facilitating Acquisition of Structural Genomic Mutations by Kampa-Schittenhelm, Kerstin Maria, Mau-Holzmann, Ulrike, Lopez, Charles, Schittenhelm, Marcus M.

    Published in Blood
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  16. 16
    Dysregulation of the ASPP Protein Family (Apoptosis Stimulating Proteins of TP53) Is a Common Feature in High-Risk Acute Myeloid Leukemia (AML)

    Dysregulation of the ASPP Protein Family (Apoptosis Stimulating Proteins of TP53) Is a Common Feature in High-Risk Acute Myeloid Leukemia (AML) by Kampa-Schittenhelm, Kerstin Maria, Kaiser, Max, Bajrami Saipi, Mihada, Walter, Bianca, Blumenstock, Gunnar, Kanz, Lothar, Schittenhelm, Marcus M

    Published in Blood
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  17. 17
    Attenuation of Apoptosis-Stimulating Protein of p53-2 (ASPP2) Promotes IL-3-Independent Growth and Enhances Cytogenetic Abnormalities after Gamma-Irradiation in Mouse Hematopoietic Cells - Mimicking Early Leukemogenesis of Therapy-Associated Human AML

    Attenuation of Apoptosis-Stimulating Protein of p53-2 (ASPP2) Promotes IL-3-Independent Growth and Enhances Cytogenetic Abnormalities after Gamma-Irradiation in Mouse Hematopoietic... by Kampa-Schittenhelm, Kerstin Maria, Mau-Holzmann, Ulrike, Kanz, Lothar, Lopez, Charles, Schittenhelm, Marcus M

    Published in Blood
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  18. 18
    ASPP2 Attenuation Is an Early Step in Leukemogenesis Facilitating Acquisition of Mutations

    ASPP2 Attenuation Is an Early Step in Leukemogenesis Facilitating Acquisition of Mutations by Kampa-Schittenhelm, Kerstin M, Akmut, Figen, Illing, Barbara, Lopez, Charles, Schittenhelm, Marcus M

    Published in Blood
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  19. 19
    Heatshockprotein-60/90 Are Overexpressed in Leukemia Stem Cells and Stabilize Oncogene Signaling

    Heatshockprotein-60/90 Are Overexpressed in Leukemia Stem Cells and Stabilize Oncogene Signaling by Kampa-Schittenhelm, Kerstin M, Kanz, Lothar, Schittenhelm, Marcus M

    Published in Blood
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  20. 20
    Epigenetic Upregulation of the O-Linked Beta-N-Acetylglucosamine Transferase (OGT) in Response to Dronabinol Results in Antileukemic Efficacy In Vivo

    Epigenetic Upregulation of the O-Linked Beta-N-Acetylglucosamine Transferase (OGT) in Response to Dronabinol Results in Antileukemic Efficacy In Vivo by Kampa-Schittenhelm, Kerstin Maria, Buehring, Hans-Joerg, Bonin, Michael, Vogel, Wichard, Kanz, Lothar, Haverkamp, Thomas, Schittenhelm, Marcus M

    Published in Blood
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