Efficacy of a novel device for cryoprevention of oral mucositis: a randomized, blinded, multicenter, parallel group, phase 3 trial by Walladbegi, Java, Henriksson, Roger, Tavelin, Björn, Svanberg, Anncarin, Larfors, Gunnar, Jädersten, Martin, Schjesvold, Fredrik, Mahdi, Aram, Garming Legert, Karin, Peterson, Douglas E., Jontell, Mats

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Autologous bone marrow Th cells can support multiple myeloma cell proliferation in vitro and in xenografted mice by Wang, D, Fløisand, Y, Myklebust, C V, Bürgler, S, Parente-Ribes, A, Hofgaard, P O, Bogen, B, Taskén, K, Tjønnfjord, G E, Schjesvold, F, Dalgaard, J, Tveita, A, Munthe, L A

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P38 PATIENT‐REPORTED OUTCOMES (PRO) IN RELAPSED/REFRACTORY MULTIPLE MYELOMA (RRMM) TREATED WITH MELFLUFEN AND DEXAMETHASONE (DEX) OR POMALIDOMIDE (POM) AND DEX: ANALYSES FROM THE P... by Schjesvold, F, Ludwig, H, Delimpasi, S, Robak, P, Mateos, M, Sandberg, A, Thuresson, M, Norin, S, Richardson, P, Sonneveld, P

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P888: REPLACING STEROIDS IN TRANSPLANT‐INELIGIBLE MULTIPLE MYELOMA: THE PHASE 2 ISATUXIMAB‐BORTEZOMIB‐LENALIDOMIDE‐DEXAMETHASONE REST STUDY by Askeland, F. B., Haukås, E., Slørdahl, T. S., Schjøll, D., Lysen, A., Hermansen, E., Schjesvold, F.

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P34 LIGHTHOUSE (OP-108): MELFLUFEN PLUS DARATUMUMAB (DARA) AND DEXAMETHASONE (DEX) VERSUS DARA IN RELAPSED/REFRACTORY MULTIPLE MYELOMA (RRMM) REFRACTORY TO AN IMMUNOMODULATORY DRUG... by Mateos, M, Szarejko, M, Bila, J, Schjesvold, F, Spicka, I, Maisnar, V, Jurczyszyn, A, Grudeva-Popova, Z, Hajek, R, Usenko, G, Thuresson, M, Norin, S, Jarefors, S, Richardson, P, Pour, L

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P938: CARFILZOMIB‐LENALIDOMIDE‐DEXAMETHASONE CONSOLIDATION IN MYELOMA PATIENTS WITH A POSITIVE FDG PET/CT AFTER UPFRONT AUTOLOGOUS STEM CELL TRANSPLANTATION: A PHASE II STUDY (CONP... by Nørgaard, J. N., Abildgaard, N., Lysén, A., Tsykunova, G., Vangsted, A. J., Joao, C., Remen, N., Osnes, L., Connelly, J. P., Revheim, M.‐E. R., Schjesvold, F.

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P901: POMALIDOMIDE, BORTEZOMIB, AND DEXAMETHASONE IN LENALIDOMIDE–PRETREATED MULTIPLE MYELOMA: A SUBANALYSIS OF OPTIMISMM BY FRAILTY by Oriol, A., Dimopoulos, M., Schjesvold, F., Beksac, M., Yagci, M., Larocca, A., Guo, S., Mu, Y., Hong, K., Dhanasiri, S., Richardson, P., Weisel, K.

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P889: WILL OUTCOME IMPROVE BY TREATING MULTIPLE MYELOMA PATIENTS AT MRD RELAPSE? THE REMNANT STUDY (RELAPSE FROM MRD NEGATIVITY AS INDICATION FOR TREATMENT) by Askeland, F. B., Rasmussen, A.‐M., Lysen, A., Haukås, E., Eilertsen, A., Moksnes, M., Tsykunova, G., Vik, A., Eiken, B. D., Sørbø, J. H., Rolke, J., Sand, K. O., Hallstensen, R. F., Myrseth, L., Slørdahl, T. S., Schjesvold, F.

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B03 CARFILZOMIB AND LENALIDOMIDE FOR PRIMARY PLASMA CELL LEUKEMIA: FINAL RESULTS OF THE PROSPECTIVE PHASE 2 EMN12/HOVON-129 STUDY FOR PATIENTS AGED ≥66 YEARS by Musto, P., Minnema, M.C., Roeloffzen, W.W.H., Capra, A., van der Holt, B., Juul Vangsted, A., Broyl, A., Schjesvold, F., Lund, T., Silkjaer, T., Benjamin, R., Grasso, M., Lung Wu, K., Caers, J., Cavo, M., Hájek, R., Bruno, B., Gadisseur, A., Pietrantuono, G., Offidani, M., Pour, L., Sonneveld, P., Boccadoro, M., van de Donk, N.

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P950: COMBINED PROTEASOME AND AUTOPHAGY INHIBITION IN RELAPSED/REFRACTORY MULTIPLE MYELOMA – A PHASE I TRIAL OF HYDROXYCHLOROQUINE, CARFILZOMIB AND DEXAMETHASONE by Slørdahl, T. S., Askeland, F. B., Hanssen, M. S. S., Sundt‐Hansen, S. M., Vethe, N. T., Hjorth‐Hansen, H., Fenstad, M. H., Waage, A., Hjertner, Ø., Schjesvold, F., Sundan, A.

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B02 CARFILZOMIB AND LENALIDOMIDE‐BASED THERAPY FOR THE TREATMENT OF PRIMARY PLASMA CELL LEUKEMIA: RESULTS OF THE FINAL ANALYSIS OF THE PROSPECTIVE PHASE 2 EMN12/HOVON‐129 STUDY FOR... by Donk, N., Minnema, M.C., Holt, B., Schjesvold, F., Wu, K.L., Capra, A., Broyl, A., Roeloffzen, W.W.H., Gadisseur, A.P.A., Pietrantuono, G., Pour, L., Velden, V., Lund, T., Offidani, M., Grasso, M., Giaccone, L., Cavo, M., Silkjaer, T., Caers, J., Zweegman, S., Hajek, R., Benjamin, R., Vangsted, A., Boccadoro, M., Gay, F., Sonneveld, P., Musto, P.

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P937: PRECLINICAL DISCOVERY AND EARLY FINDINGS FROM THE PHASE 1, DOSE‐ESCALATION STUDY OF WVT078, A BCMA‐CD3 BISPECIFIC ANTIBODY, IN PATIENTS WITH R/R MULTIPLE MYELOMA by Raab, M. S., Cohen, Y. C., Schjesvold, F., Aardalen, K., Oka, A., Spencer, A., Wermke, M., Hari, P., Kaufman, J. L., Cafro, A. M., Ocio, E. M., Doki, N., Henson, K., Trabucco, G., Juif, P.‐E., Chawla, R., Cotton, J., Fessehatsion, A., Fan, L., Blankenship, J., Granda, B., Lu, H., De Vita, S.

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Primary plasma cell leukemia: consensus definition by the International Myeloma Working Group according to peripheral blood plasma cell percentage by Fernández de Larrea, Carlos, Kyle, Robert, Rosiñol, Laura, Paiva, Bruno, Engelhardt, Monika, Usmani, Saad, Caers, Jo, Gonsalves, Wilson, Schjesvold, Fredrik, Merlini, Giampaolo, Lentzch, Suzanne, Ocio, Enrique, Garderet, Laurent, Moreau, Philippe, Sonneveld, Pieter, Badros, Ashraf, Gahrton, Gösta, Goldschmidt, Hartmut, Tuchman, Sascha, Einsele, Hermann, Durie, Brian, Wirk, Baldeep, Musto, Pellegrino, Hayden, Patrick, Kaiser, Martin, Miguel, Jesús San, Bladé, Joan, Rajkumar, S. Vincent, Mateos, Maria Victoria

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Pomalidomide, bortezomib, and dexamethasone for patients with relapsed or refractory multiple myeloma previously treated with lenalidomide (OPTIMISMM): a randomised, open-label, ph... by Richardson, Paul G, Beksac, Meral, Liberati, Anna Marina, Galli, Monica, Lindsay, Jindriska, White, Darrell, Facon, Thierry, San Miguel, Jesus, Sunami, Kazutaka, O'Gorman, Peter, Sonneveld, Pieter, Robak, Pawel, Schey, Steve, Yu, Xin, Bensmaine, Amine, Zaki, Mohamed, Abildgaard, Niels, Adler, Howard, Altuntas, Fevzi, Arce-Lara, Carlos, Aydin, Yildiz, Basu, Supratik, Battini, Ramakrishna, Beeker, Thaddeus, Ben-Yehuda, Dina, Boccia, Ralph, Cavo, Michele, Chantry, Andrew, Chaudhry, Arvind, Corso, Alessandro, De Arriba, Felipe, Delimpasi, Sosana, Desjardins, Pierre, Dhakal, Binod, Di Bartolomeo, Paolo, Dürig, Jan, Engelhardt, Monika, Esteves, Graca, Flogegard, Max, Gabrail, Nashat, Gamberi, Barbara, Garrison, Mitchell, Gisslinger, Heinz, Goldschmidt, Hartmut, Gressot, Laurent, Grosicki, Sebastian, Hanna, Wahid, Henriques Bernardo, Maria Manuela, Hermann, Robert, Holden, Viran, Huben, Marianne, Janakiram, Murali, Jenner, Matthew, João, Cristina, Jurcyszyn, Artur, Kalayoğlu Beşişik, Sevgi, Kambhampati, Suman, Karadoğan, Ihsan, Khojasteh, Ali, Kirkel, Dean, Komarnicki, Mieczyslaw, Lauri, Birgitta, Leleu, Xavier, Matsue, Kosei, Mendeleeva, Larisa, Miller, Carole, Mohrbacher, Ann, Müldür, Ercan, Naassan, Anthony, Nahi, Hareth, Nair, Rajesh, O'Dwyer, Mike, Openshaw, Thomas, O'Rourke, Timothy, Osswald, Michael, Overton, Lindsay, Pavic, Michel, Pierola, Ana Alfonso, Rabin, Neil, Ramasamy, Karthik, Rambaldi, Alessandro, Rodriguez, Paula, Röllig, Christoph, Rosenblatt, Jacalyn, Rosenbluth, Jonathan, Salomo, Morten, Samoylova, Olga, Sastre Moral, Jose, Shafeek, Salim, Shinagawa, Atsushi, Sleckman, Bethany, Smith, Clay, Suzuki, Kenshi, Takezako, Naoki, Teke, Hava Üsküdar, Vapaatalo, Mirja, Vassilopoulos, George, Verma, Amit, Wang, Xiang Sean, Yağci, Munci

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S824 A PHASE 3 RANDOMIZED, OPEN‐LABEL, MULTICENTER STUDY OF ISATUXIMAB, POMALIDOMIDE, AND LOW‐DOSE DEXAMETHASONE VS POMALIDOMIDE AND LOW‐DOSE DEXAMETHASONE IN RELAPSED/REFRACTORY M... by Attal, M., Richardson, P.G., Rajkumar, S.V., San‐Miguel, J., Beksac, M., Spicka, I., Leleu, X., Schjesvold, F., Moreau, P., Dimopoulos, M.A., Huang, J.S.‐Y., Minarik, J., Cavo, M., Prince, H.M., Mace, S., Corzo, K.P., Campana, F., Le‐Guennec, S., Dubin, F., Anderson, K.C.

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PB2116 EVOLUTION OF MULTIPLE MYELOMA MANAGEMENT IN NORWAY: EXPERT OPINION 2013–2018 by Schjesvold, F. H.

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Treatment of relapsed and refractory multiple myeloma: recommendations from the International Myeloma Working Group by Moreau, Philippe, Kumar, Shaji K, San Miguel, Jesús, Davies, Faith, Zamagni, Elena, Bahlis, Nizar, Ludwig, Heinz, Mikhael, Joseph, Terpos, Evangelos, Schjesvold, Fredrik, Martin, Thomas, Yong, Kwee, Durie, Brian G M, Facon, Thierry, Jurczyszyn, Artur, Sidana, Surbhi, Raje, Noopur, van de Donk, Niels, Lonial, Sagar, Cavo, Michele, Kristinsson, Sigurdur Y, Lentzsch, Suzanne, Hajek, Roman, Anderson, Kenneth C, João, Cristina, Einsele, Hermann, Sonneveld, Pieter, Engelhardt, Monika, Fonseca, Rafael, Vangsted, Annette, Weisel, Katja, Baz, Rachid, Hungria, Vania, Berdeja, Jesus G, Leal da Costa, Fernando, Maiolino, Angelo, Waage, Anders, Vesole, David H, Ocio, Enrique M, Quach, Hang, Driessen, Christoph, Bladé, Joan, Leleu, Xavier, Riva, Eloisa, Bergsagel, Peter Leif, Hou, Jian, Chng, Wee Joo, Mellqvist, Ulf-Henrik, Dytfeld, Dominik, Harousseau, Jean-Luc, Goldschmidt, Hartmut, Laubach, Jacob, Munshi, Nikhil C, Gay, Francesca, Beksac, Meral, Costa, Luciano J, Kaiser, Martin, Hari, Parameswaran, Boccadoro, Mario, Usmani, Saad Z, Zweegman, Sonja, Holstein, Sarah, Sezer, Orhan, Harrison, Simon, Nahi, Hareth, Cook, Gordon, Mateos, Maria-Victoria, Rajkumar, S Vincent, Dimopoulos, Meletios A, Richardson, Paul G

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P905: IXAZOMIB‐THALIDOMIDE‐DEXAMETHASONE INDUCTION FOLLOWED BY IXAZOMIB OR PLACEBO MAINTENANCE IN NON‐TRANSPLANT ELIGIBLE NEWLY DIAGNOSED MULTIPLE MYELOMA PATIENTS; LONG‐TERM RESUL... by Groen, K., Seefat, M. R., Holt, B., Schjesvold, F. H., Stege, C. A., Levin, M.‐D., Hansson, M., Leys, R. B., Regelink, J., Waage, A., Szatkowski, D., Axelsson, P., Do, T. H., Svirskaite, A., Spek, E., Haukas, E., Knut‐Bojanowska, D., Ypma, P. F., Blimark, C., Mellqvist, U.‐H., Donk, N. W., Sonneveld, P., Klostergaard, A., Vangsted, A. J., Abdilgaard, N., Zweegman, S.

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Carfilzomib and dexamethasone maintenance following salvage ASCT in multiple myeloma: A randomised phase 2 trial by the Nordic Myeloma Study Group by Gregersen, Henrik, Peceliunas, Valdas, Remes, Kari, Schjesvold, Fredrik, Abildgaard, Niels, Nahi, Hareth, Andersen, Niels Frost, Vangsted, Annette Juul, Klausen, Tobias Wirenfeldt, Helleberg, Carsten, Carlson, Kristina, Frølund, Ulf Christian, Axelsson, Per, Stromberg, Olga, Blimark, Cecilie Hveding, Crafoord, Jacob, Tsykunova, Galina, Eshoj, Henrik Rode, Waage, Anders, Hansson, Markus, Gulbrandsen, Nina

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EE73 Ocean (OP-103): Patients with Relapsed/Refractory Multiple Myeloma Treated with Melflufen Plus Dexamethasone or Pomalidomide Plus Dexamethasone - a Resource Utilization Analys... by Hellem Schjesvold, F., Ludwig, H., Delimpasi, S., Robak, P., Mateos, M.V., Sandberg, A., Obermüller, J., Norin, S., Richardson, P.G., Sonneveld, P.

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