Abstract 19086: Reducing Infarct Size by Protection of Ischemic Myocardium With Targeted Growth Factors by Chang, Henry H, Zhang, Yan, Stowe, Timothy R, Kuchenbecker, Kristopher M, Millard, Bjorn L, Nickerson, Andrea D, Schoeberl, Birgit M, Nielson, Ulrik B

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Dual Inhibition of IGF-1R and ErbB3 Enhances the Activity of Gemcitabine and Nab-Paclitaxel in Preclinical Models of Pancreatic Cancer by Camblin, Adam J, Pace, Emily A, Adams, Sharlene, Curley, Michael D, Rimkunas, Victoria, Nie, Lin, Tan, Gege, Bloom, Troy, Iadevaia, Sergio, Baum, Jason, Minx, Charlene, Czibere, Akos, Louis, Chrystal U, Drummond, Daryl C, Nielsen, Ulrik B, Schoeberl, Birgit, Pipas, J Marc, Straubinger, Robert M, Askoxylakis, Vasileios, Lugovskoy, Alexey A

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An Activated ErbB3/NRG1 Autocrine Loop Supports In Vivo Proliferation in Ovarian Cancer Cells by Sheng, Qing, Liu, Xinggang, Fleming, Eleanor, Yuan, Karen, Piao, Huiying, Chen, Jinyun, Moustafa, Zeinab, Thomas, Roman K., Greulich, Heidi, Schinzel, Anna, Zaghlul, Sara, Batt, David, Ettenberg, Seth, Meyerson, Matthew, Schoeberl, Birgit, Kung, Andrew L., Hahn, William C., Drapkin, Ronny, Livingston, David M., Liu, Joyce F.

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Ten simple rules to power drug discovery with data science by Ferrero, Enrico, Brachat, Sophie, Jenkins, Jeremy L, Marc, Philippe, Skewes-Cox, Peter, Altshuler, Robert C, Gubser Keller, Caroline, Kauffmann, Audrey, Sassaman, Erik K, Laramie, Jason M, Schoeberl, Birgit, Borowsky, Mark L, Stiefl, Nikolaus

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Viral Kinetics Model of SARS‐CoV‐2 Infection Informs Drug Discovery, Clinical Dose, and Regimen Selection by Claas, Allison M., Lee, Meelim, Huang, Pai‐Hsi, Knutson, Charles G., Bullara, Domenico, Schoeberl, Birgit, Gaudet, Suzanne

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Abstract 3842: Design and engineering of TRAIL fusion proteins for cancer therapy by Tam, Eric M., Hudson, Hannah, Dake, Tamara, Ghassemifar, Sara, Raue, Andreas, Hashambhoy-Ramsay, Yasmin, Sazinsky, Stephen L., Daruwalla, Anahita, Kohli, Neeraj, Xu, Lihui, Mc Donagh, Charlotte F., Schoeberl, Birgit, Chai, Diana H.

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Abstract 2077A: MM141, a novel bispecific antibody co-inhibitor of IGF-1R and ErbB3, inhibits the proliferation of melanoma cells by Von Euw, Erika M., Pace, Emily, Covarrubias, Karina, Jairam, Abhi, Chai, Diana, Konkankit, Veerauo, Gong, Ke-Wei, Johnson, Bryan, Schoeberl, Birgit, Lugovskoy, Alexey, Richard, Finn, Slamon, Dennis

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Abstract LB-410: Phase I dose escalation study of MM-121, a fully human monoclonal antibody to ErbB3, in patients with advanced solid tumors by Denlinger, Crystal S., Keedy, Vicki L., Cleary, James M., Kubasek, William, Onsum, Matthew, Moulis, Sharon, Garcia, Gabriela, Schoeberl, Birgit, MacBeath, Gavin, Nering, Rachel, Murray, James, Moyo, Victor, Wong, Kwok-Kin, Shapiro, Geoffrey

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