Biochemical and structural investigations clarify the substrate selectivity of the 2-oxoglutarate oxygenase JMJD6 by Islam, Md. Saiful, McDonough, Michael A., Chowdhury, Rasheduzzaman, Gault, Joseph, Khan, Amjad, Pires, Elisabete, Schofield, Christopher J.

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Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors by Tian, Ya-Min, Yeoh, Kar Kheng, Lee, Myung Kyu, Eriksson, Tuula, Kessler, Benedikt M., Kramer, Holger B., Edelmann, Mariola J., Willam, Carsten, Pugh, Christopher W., Schofield, Christopher J., Ratcliffe, Peter J.

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Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy by Loenarz, Christoph, Sekirnik, Rok, Thalhammer, Armin, Ge, Wei, Spivakovsky, Ekaterina, Mackeen, Mukram M., McDonough, Michael A., Cockman, Matthew E., Kessler, Benedikt M., Ratcliffe, Peter J., Wolf, Alexander, Schofield, Christopher J.

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JMJD5 is a human arginyl C-3 hydroxylase by Wilkins, Sarah E., Islam, Md. Saiful, Gannon, Joan M., Markolovic, Suzana, Hopkinson, Richard J., Ge, Wei, Schofield, Christopher J., Chowdhury, Rasheduzzaman

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Structural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO) by Aik, WeiShen, Demetriades, Marina, Hamdan, Muhammad K. K, Bagg, Eleanor. A. L, Yeoh, Kar Kheng, Lejeune, Clarisse, Zhang, Zhihong, McDonough, Michael A, Schofield, Christopher J

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Human prolyl hydroxylase domain 2 reacts with O2 and 2-oxoglutarate to enable formation of inactive Fe(III).2OG.hypoxia-inducible-factor α complexes by Fiorini, Giorgia, Marshall, Stephen A., Figg, William D., Myers, William K., Brewitz, Lennart, Schofield, Christopher J.

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Aspartate/asparagine-β-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern by Pfeffer, Inga, Brewitz, Lennart, Krojer, Tobias, Jensen, Sacha A., Kochan, Grazyna T., Kershaw, Nadia J., Hewitson, Kirsty S., McNeill, Luke A., Kramer, Holger, Münzel, Martin, Hopkinson, Richard J., Oppermann, Udo, Handford, Penny A., McDonough, Michael A., Schofield, Christopher J.

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Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans by Chowdhury, Rasheduzzaman, Abboud, Martine I., Wiley, James, Tumber, Anthony, Markolovic, Suzana, Schofield, Christopher J.

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Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α) by Thalhammer, Armin, Bencokova, Zuzana, Poole, Rachel, Loenarz, Christoph, Adam, Julie, O'Flaherty, Linda, Schödel, Johannes, Mole, David, Giaslakiotis, Konstantinos, Schofield, Christopher J, Hammond, Ester M, Ratcliffe, Peter J, Pollard, Patrick J

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OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation by Singleton, Rachelle S., Liu-Yi, Phebee, Formenti, Fabio, Ge, Wei, Sekirnik, Rok, Fischer, Roman, Adam, Julie, Pollard, Patrick J., Wolf, Alexander, Thalhammer, Armin, Loenarz, Christoph, Flashman, Emily, Yamamoto, Atsushi, Coleman, Mathew L., Kessler, Benedikt M., Wappner, Pablo, Schofield, Christopher J., Ratcliffe, Peter J., Cockman, Matthew E.

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Targeting Protein-Protein Interactions in the HIF System by Wilkins, Sarah E., Abboud, Martine I., Hancock, Rebecca L., Schofield, Christopher J.

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Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay by Ehrismann, Dominic, Flashman, Emily, Genn, David N, Mathioudakis, Nicolas, Hewitson, Kirsty S, Ratcliffe, Peter J, Schofield, Christopher J

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Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family by Hillringhaus, Lars, Yue, Wyatt W., Rose, Nathan R., Ng, Stanley S., Gileadi, Carina, Loenarz, Christoph, Bello, Simon H., Bray, James E., Schofield, Christopher J., Oppermann, Udo

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SNM1A is crucial for efficient repair of complex DNA breaks in human cells by Swift, Lonnie P., Lagerholm, B. Christoffer, Henderson, Lucy R., Ratnaweera, Malitha, Baddock, Hannah T., Sengerova, Blanka, Lee, Sook, Cruz-Migoni, Abimael, Waithe, Dominic, Renz, Christian, Ulrich, Helle D., Newman, Joseph A., Schofield, Christopher J., McHugh, Peter J.

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Direct sulfonylation of anilines mediated by visible light by Johnson, Tarn C, Elbert, Bryony L, Farley, Alistair J M, Gorman, Timothy W, Genicot, Christophe, Lallemand, Bénédicte, Pasau, Patrick, Flasz, Jakub, Castro, José L, MacCoss, Malcolm, Dixon, Darren J, Paton, Robert S, Schofield, Christopher J, Smith, Martin D, Willis, Michael C

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Pan-Histone Demethylase Inhibitors Simultaneously Targeting Jumonji C and Lysine-Specific Demethylases Display High Anticancer Activities by Rotili, Dante, Tomassi, Stefano, Conte, Mariarosaria, Benedetti, Rosaria, Tortorici, Marcello, Ciossani, Giuseppe, Valente, Sergio, Marrocco, Biagina, Labella, Donatella, Novellino, Ettore, Mattevi, Andrea, Altucci, Lucia, Tumber, Anthony, Yapp, Clarence, King, Oliver N. F, Hopkinson, Richard J, Kawamura, Akane, Schofield, Christopher J, Mai, Antonello

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Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain by Chan, Mun Chiang, Atasoylu, Onur, Hodson, Emma, Tumber, Anthony, Leung, Ivanhoe K H, Chowdhury, Rasheduzzaman, Gómez-Pérez, Verónica, Demetriades, Marina, Rydzik, Anna M, Holt-Martyn, James, Tian, Ya-Min, Bishop, Tammie, Claridge, Timothy D W, Kawamura, Akane, Pugh, Christopher W, Ratcliffe, Peter J, Schofield, Christopher J

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Structural Basis for Binding of Hypoxia-Inducible Factor to the Oxygen-Sensing Prolyl Hydroxylases by Chowdhury, Rasheduzzaman, McDonough, Michael A., Mecinović, Jasmin, Loenarz, Christoph, Flashman, Emily, Hewitson, Kirsty S., Domene, Carmen, Schofield, Christopher J.

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Emulsion PCR Significantly Improves Nonequilibrium Capillary Electrophoresis of Equilibrium Mixtures-Based Aptamer Selection: Allowing for Efficient and Rapid Selection of Aptamer... by Yufa, Roman, Krylova, Svetlana M, Bruce, Christine, Bagg, Eleanor A, Schofield, Christopher J, Krylov, Sergey N

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Adipocyte deletion of the oxygen-sensor PHD2 sustains elevated energy expenditure at thermoneutrality by Wang, Rongling, Gomez Salazar, Mario, Pruñonosa Cervera, Iris, Coutts, Amanda, French, Karen, Pinto, Marlene Magalhaes, Gohlke, Sabrina, García-Martín, Ruben, Blüher, Matthias, Schofield, Christopher J., Kourtzelis, Ioannis, Stimson, Roland H., Bénézech, Cécile, Christian, Mark, Schulz, Tim J., Gudmundsson, Elias F., Jennings, Lori L., Gudnason, Vilmundur G., Chavakis, Triantafyllos, Morton, Nicholas M., Emilsson, Valur, Michailidou, Zoi

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