Unmet Medical Need: An Introduction to Definitions and Stakeholder Perceptions by Vreman, Rick A., PharmD, Heikkinen, Inkatuuli, MSc, MHEcon, Schuurman, Ad, MSc, MBA, Sapede, Claudine, PharmD, Garcia, Jordi Llinares, PhD, Hedberg, Niklas, PharmD, Athanasiou, Dimitrios, MBA, Grueger, Jens, PhD, Leufkens, Hubert G.M., PhD, Goettsch, Wim G., PhD

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Paying for the Orphan Drug System: break or bend? Is it time for a new evaluation system for payers in Europe to take account of new rare disease treatments? by Hughes-Wilson, Wills, Palma, Ana, Schuurman, Ad, Simoens, Steven

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Adaptive Pathways: Possible Next Steps for Payers in Preparation for Their Potential Implementation by Vella Bonanno, Patricia, Ermisch, Michael, Godman, Brian, Martin, Antony P, Van Den Bergh, Jesper, Bezmelnitsyna, Liudmila, Bucsics, Anna, Arickx, Francis, Bybau, Alexander, Bochenek, Tomasz, van de Casteele, Marc, Diogene, Eduardo, Eriksson, Irene, Fürst, Jurij, Gad, Mohamed, Greičiūtė-Kuprijanov, Ieva, van der Graaff, Martin, Gulbinovic, Jolanta, Jones, Jan, Joppi, Roberta, Kalaba, Marija, Laius, Ott, Langner, Irene, Mardare, Ileana, Markovic-Pekovic, Vanda, Magnusson, Einar, Melien, Oyvind, Meshkov, Dmitry O, Petrova, Guenka I, Selke, Gisbert, Sermet, Catherine, Simoens, Steven, Schuurman, Ad, Ramos, Ricardo, Rodrigues, Jorge, Zara, Corinne, Zebedin-Brandl, Eva, Haycox, Alan

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Payers' Views of the Changes Arising through the Possible Adoption of Adaptive Pathways by Ermisch, Michael, Bucsics, Anna, Vella Bonanno, Patricia, Arickx, Francis, Bybau, Alexander, Bochenek, Tomasz, van de Casteele, Marc, Diogene, Eduardo, Fürst, Jurij, Garuolienė, Kristina, van der Graaff, Martin, Gulbinovič, Jolanta, Haycox, Alan, Jones, Jan, Joppi, Roberta, Laius, Ott, Langner, Irene, Martin, Antony P, Markovic-Pekovic, Vanda, McCullagh, Laura, Magnusson, Einar, Nilsen, Ellen, Selke, Gisbert, Sermet, Catherine, Simoens, Steven, Sauermann, Robert, Schuurman, Ad, Ramos, Ricardo, Vlahovic-Palcevski, Vera, Zara, Corinne, Godman, Brian

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Data Rich, Information Poor: Can We Use Electronic Health Records to Create a Learning Healthcare System for Pharmaceuticals? by Eichler, Hans‐Georg, Bloechl‐Daum, Brigitte, Broich, Karl, Kyrle, Paul Alexander, Oderkirk, Jillian, Rasi, Guido, Santos Ivo, Rui, Schuurman, Ad, Senderovitz, Thomas, Slawomirski, Luke, Wenzl, Martin, Paris, Valerie

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Payers' Views of the Changes Arising through the Possible Adoption of Adaptive Pathways by Ermisch, M, Bucsics, A, Bonanno, PV, Arickx, F, Bybau, A, Bochenek, T, van de Casteele, M, Diogene, E, Furst, J, Garuoliene, K, van der Graaff, M, Gulbinovic, J, Haycox, A, Jones, J, Joppi, R, Laius, O, Langner, I, Martin, AP, Markovic-Pekovic, V, McCullagh, L, Magnusson, E, Nilsen, E, Selke, G, Sermet, C, Simoens, S, Sauermann, R, Schuurman, A, Ramos, R, Vlahovic-Palcevski, V, Zara, C, Godman, B

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The fourth edition of the European Network for Health Technology Assessment Forum: highlights and outcomes by Tafuri, Giovanni, Bélorgey, Chantal, Favaretti, Carlo, Frénoy, Edith, Giorgio, Flora, Guardian, Marcus, Hebborn, Ansgar, Houÿez, François, Imbert, Jessica, Lacombe, Denis, Garcia, Jordi Llinares, Garrett, Zoe, Petelos, Elena, Saeterdal, Ingvil, Schuurman, Ad, Skjöldebrand, Anna Lefevre, Strammiello, Valentina, Widmer, Daniel, Willemsen, Anne, Hedberg, Niklas

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The inter-heavy chain disulfide bonds of IgG4 are in equilibrium with intra-chain disulfide bonds by Schuurman, Janine, Perdok, Gerrard J, Gorter, Annelies D, Aalberse, Rob C

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