Search Results - Scopton, Alex P.

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  1. 1
    Structural basis for the action of the drug trametinib at KSR-bound MEK

    Structural basis for the action of the drug trametinib at KSR-bound MEK by Khan, Zaigham M., Real, Alexander M., Marsiglia, William M., Chow, Arthur, Duffy, Mary E., Yerabolu, Jayasudhan R., Scopton, Alex P., Dar, Arvin C.

    Published in Nature (London)
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  2. 2
    Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network

    Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network by Ung, Peter M U, Sonoshita, Masahiro, Scopton, Alex P, Dar, Arvin C, Cagan, Ross L, Schlessinger, Avner

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  3. 3
    Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling

    Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling by Dhawan, Neil S., Scopton, Alex P., Dar, Arvin C.

    Published in Nature (London)
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  4. 4
    Identification of novel functionally selective κ-opioid receptor scaffolds

    Identification of novel functionally selective κ-opioid receptor scaffolds by White, Kate L, Scopton, Alex P, Rives, Marie-Laure, Bikbulatov, Ruslan V, Polepally, Prabhakar R, Brown, Peter J, Kenakin, Terrance, Javitch, Jonathan A, Zjawiony, Jordan K, Roth, Bryan L

    Published in Molecular pharmacology
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  5. 5
    Type II Binders Targeting the “GLR-Out” Conformation of the Pseudokinase STRADα

    Type II Binders Targeting the “GLR-Out” Conformation of the Pseudokinase STRADα by Smith, Ryan H. B, Khan, Zaigham M, Ung, Peter Man-Un, Scopton, Alex P, Silber, Lisa, Mack, Seshat M, Real, Alexander M, Schlessinger, Avner, Dar, Arvin C

    Published in Biochemistry (Easton)
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  6. 6
    Enantioselective Pathway for the Synthesis of Laurenditerpenol

    Enantioselective Pathway for the Synthesis of Laurenditerpenol by Mukherjee, Santanu, Scopton, Alex P, Corey, E. J

    Published in Organic letters
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  7. 7
    WNTinib is a multi-kinase inhibitor with specificity against β-catenin mutant hepatocellular carcinoma

    WNTinib is a multi-kinase inhibitor with specificity against β-catenin mutant hepatocellular carcinoma by Rialdi, Alex, Duffy, Mary, Scopton, Alex P, Fonseca, Frank, Zhao, Julia Nanyi, Schwarz, Megan, Molina-Sanchez, Pedro, Mzoughi, Slim, Arceci, Elisa, Abril-Fornaguera, Jordi, Meadows, Austin, Ruiz de Galarreta, Marina, Torre, Denis, Reyes, Kyna, Lim, Yan Ting, Rosemann, Felix, Khan, Zaigham M, Mohammed, Kevin, Wang, Xuedi, Yu, Xufen, Lakshmanan, Manikandan, Rajarethinam, Ravisankar, Tan, Soo Yong, Jin, Jian, Villanueva, Augusto, Michailidis, Eleftherios, De Jong, Ype P, Rice, Charles M, Marazzi, Ivan, Hasson, Dan, Llovet, Josep M, Sobota, Radoslaw M, Lujambio, Amaia, Guccione, Ernesto, Dar, Arvin C

    Published in Nature cancer
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