Search Results - Scruggs, Darah A

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  1. 1
    AML-147 C-MYC Targeting by Degradation: Novel Dual c-Myc/GSPT1 Degrader GT19715 Exerts Profound Cell Kill In Vitro and In Vivo in Acute Myeloid Leukemia and Lymphomas

    AML-147 C-MYC Targeting by Degradation: Novel Dual c-Myc/GSPT1 Degrader GT19715 Exerts Profound Cell Kill In Vitro and In Vivo in Acute Myeloid Leukemia and Lymphomas by Nishida, Yuki, Scruggs, Darah A, Ayoub, Edward, Patsilevas, Tallie, Ruvolo, Vivian R, Mak, Po Yee, Carter, Bing Z, Boettcher, Steffen, Maiti, Abhishek, Zhou, Qianxiang, Yang, Zhaohui, Yan, Honghua, Ma, Liandong, Andreeff, Michael

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  2. 2
    Enhanced TP53 reactivation disrupts MYC transcriptional program and overcomes venetoclax resistance in acute myeloid leukemias

    Enhanced TP53 reactivation disrupts MYC transcriptional program and overcomes venetoclax resistance in acute myeloid leukemias by Nishida, Yuki, Ishizawa, Jo, Ayoub, Edward, Montoya, Rafael Heinz, Ostermann, Lauren B, Muftuoglu, Muharrem, Ruvolo, Vivian R, Patsilevas, Tallie, Scruggs, Darah A, Khazaei, Shayaun, Mak, Po Yee, Tao, Wenjing, Carter, Bing Z, Boettcher, Steffen, Ebert, Benjamin L, Daver, Naval G, Konopleva, Marina, Seki, Takahiko, Kojima, Kensuke, Andreeff, Michael

    Published in Science advances
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  3. 3
    C-MYC Targeting By Degradation: Novel Dual c-Myc/GSPT1 Degrader GT19715 Induces TP53-Independent Cell Death in Acute Myeloid Leukemia and Lymphomas

    C-MYC Targeting By Degradation: Novel Dual c-Myc/GSPT1 Degrader GT19715 Induces TP53-Independent Cell Death in Acute Myeloid Leukemia and Lymphomas by Nishida, Yuki, Scruggs, Darah A, Ayoub, Edward, Patsilevas, Tallie, Ruvolo, Vivian, Mak, Po Yee, Carter, Bing Z, Boettcher, Steffen, Maiti, Abhishek, Zhou, Qianxiang, Yang, Zhaohui, Yan, Honghua, Ma, Liandong, Andreeff, Michael

    Published in Blood
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  4. 4
    Poster: AML-147 C-MYC Targeting by Degradation: Novel Dual c-Myc/GSPT1 Degrader GT19715 Exerts Profound Cell Kill In Vitro and In Vivo in Acute Myeloid Leukemia and Lymphomas

    Poster: AML-147 C-MYC Targeting by Degradation: Novel Dual c-Myc/GSPT1 Degrader GT19715 Exerts Profound Cell Kill In Vitro and In Vivo in Acute Myeloid Leukemia and Lymphomas by Nishida, Yuki, Scruggs, Darah A, Ayoub, Edward, Patsilevas, Tallie, Ruvolo, Vivian R, Mak, Po Yee, Carter, Bing Z, Boettcher, Steffen, Maiti, Abhishek, Zhou, Qianxiang, Yang, Zhaohui, Yan, Honghua, Ma, Liandong, Andreeff, Michael

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  5. 5
    Abstract A31: C-MYC Targeting by Degradation: Novel Dual c-MYC/GSPT1 Degrader GT19715 Induces TP53-independent Cell Death in MYC-amplified Acute Myeloid Leukemia and Lymphomas

    Abstract A31: C-MYC Targeting by Degradation: Novel Dual c-MYC/GSPT1 Degrader GT19715 Induces TP53-independent Cell Death in MYC-amplified Acute Myeloid Leukemia and Lymphomas by Nishida, Yuki, Scruggs, Darah A, Ayoub, Edward, Ostermann, Lauren B, Patsilevas, Tallie, Ruvolo, Vivian R, Mak, Po Yee, Carter, Bing Z., Boettcher, Steffen, Maiti, Abhishek, Sasaki, Koji, Zhou, Qianxiang, Yang, Zhaohui, Yan, Honghua, Ma, Liandong, Andreeff, Michael

    Published in Blood cancer discovery
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  6. 6
    Targeting Co-Regulatory Feedback Loop of MYC and GSPT1 By MYC/GSPT1 Dual Degradation Is Synthetic Lethal in Combination with Ven/Aza in TP53 Mutant Acute Myeloid Leukemia Stem and Progenitor Cells

    Targeting Co-Regulatory Feedback Loop of MYC and GSPT1 By MYC/GSPT1 Dual Degradation Is Synthetic Lethal in Combination with Ven/Aza in TP53 Mutant Acute Myeloid Leukemia Stem and... by Nishida, Yuki, Mizuno, Hideaki, Ayoub, Edward, Sugihara, Eiji, Ostermann, Lauren B., Khazaei, Shayaun, Scruggs, Darah, Mak, Po Yee, Ke, Baozhen, Carter, Bing Z., Maiti, Abhishek, Ma, Liandong, Andreeff, Michael

    Published in Blood
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  7. 7
    Targeted Protein Degradation for c-MYC Overcomes Therapy Resistance in T-Cell Acute Lymphoblastic Leukemias

    Targeted Protein Degradation for c-MYC Overcomes Therapy Resistance in T-Cell Acute Lymphoblastic Leukemias by Munir, Faryal, Khazaei, Shayaun, Calkins, Phoebe H., Scruggs, Darah, Mizuno, Hideaki, Ostermann, Lauren B., Cuglievan, Branko, Garcia, Miriam B., Chen, Dong, Tong, Youzhi, Ren, Zhihua, Andreeff, Michael, Nishida, Yuki

    Published in Blood
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  8. 8
    Stem-Cell Enriched Cellular Hierarchy of TP53 Mutant Acute Myeloid Leukemia Is Vulnerable to Targeted Protein Degradation of c-MYC

    Stem-Cell Enriched Cellular Hierarchy of TP53 Mutant Acute Myeloid Leukemia Is Vulnerable to Targeted Protein Degradation of c-MYC by Nishida, Yuki, Ayoub, Edward, Scruggs, Darah, Khazaei, Shayaun, Munir, Faryal, Ostermann, Lauren B., Mak, Po Yee, Baozhen, Ke, Carter, Bing Z., Baran, Natalia, Maiti, Abhishek, Mohanty, Vakul, Chen, Ken, Navin, Nicholas, Haferlach, Torsten, Ren, Zhihua, Tong, Youzhi, Chen, Dong, Issa, Ghayas C., Andreeff, Michael

    Published in Blood
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