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2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo Efficacy
by
Dziwornu, Godwin Akpeko
,
Seanego, Donald
,
Fienberg, Stephen
,
Clements, Monica
,
Ferreira, Jasmin
,
Sypu, Venkata S.
,
Samanta, Sauvik
,
Bhana, Ashlyn D.
,
Korkor, Constance M.
,
Garnie, Larnelle F.
,
Teixeira, Nicole
,
Wicht, Kathryn J.
,
Taylor, Dale
,
Olckers, Ronald
,
Njoroge, Mathew
,
Gibhard, Liezl
,
Salomane, Nicolaas
,
Wittlin, Sergio
,
Mahato, Rohit
,
Chakraborty, Arnish
,
Sevilleno, Nicole
,
Coyle, Rachael
,
Lee, Marcus C. S.
,
Godoy, Luiz C.
,
Pasaje, Charisse Flerida
,
Niles, Jacquin C.
,
Reader, Janette
,
van der Watt, Mariette
,
Birkholtz, Lyn-Marié
,
Bolscher, Judith M.
,
de Bruijni, Marloes H. C.
,
Coulson, Lauren B.
,
Basarab, Gregory S.
,
Ghorpade, Sandeep R.
,
Chibale, Kelly
Published in
Journal of medicinal chemistry
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Discovery of Non-Covalent Inhibitors for SARS-CoV‑2 PLpro: Integrating Virtual Screening, Synthesis, and Experimental Validation
by
Sousa, Bruna K. P.
,
Mottin, Melina
,
Seanego, Donald
,
Jurisch, Christopher D.
,
Rodrigues, Beatriz S. A.
,
da Silva, Verônica L. S.
,
Andrade, Milene Aparecida
,
Boerin, Diogo F.
,
Froes, Thamires Q.
,
Motta, Flávia Nader
,
Nonato, M. Cristina
,
Bastos, Izabela D. M.
,
Chibale, Kelly
,
Gessner, Richard K.
,
Andrade, Carolina Horta
Published in
ACS medicinal chemistry letters
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Journal Title
Acs Medicinal Chemistry Letters
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Journal Of Medicinal Chemistry
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Subjects
Chemistry, Medicinal
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Life Sciences & Biomedicine
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Pharmacology & Pharmacy
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Science & Technology
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1-Phosphatidylinositol 4-Kinase - Antagonists & Inhibitors
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1-Phosphatidylinositol 4-Kinase - Metabolism
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Animals
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Antimalarials - Chemical Synthesis
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Antimalarials - Chemistry
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Antimalarials - Pharmacology
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Hemeproteins - Antagonists & Inhibitors
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Hemeproteins - Metabolism
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Humans
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Letter
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Malaria, Falciparum - Drug Therapy
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Male
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Mice
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Naphthyridines - Chemical Synthesis
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Naphthyridines - Chemistry
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Naphthyridines - Pharmacology
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Access Via American Chemical Society
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Acs Crkn Legacy Archives
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Ezb-Free-00999 Freely Available Ezb Journals
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Pubmed Central
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