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Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain
by
Brand, Michael
,
Clayton, James
,
Moroglu, Mustafa
,
Schiedel, Matthias
,
Picaud, Sarah
,
Bluck, Joseph P
,
Skwarska, Anna
,
Bolland, Hannah
,
Chan, Anthony K. N
,
Laurin, Corentine M. C
,
Scorah, Amy R
,
See, Larissa
,
Rooney, Timothy P. C
,
Andrews, Katrina H
,
Fedorov, Oleg
,
Perell, Gabriella
,
Kalra, Prakriti
,
Vinh, Kayla B
,
Cortopassi, Wilian A
,
Heitel, Pascal
,
Christensen, Kirsten E
,
Cooper, Richard I
,
Paton, Robert S
,
Pomerantz, William C. K
,
Biggin, Philip C
,
Hammond, Ester M
,
Filippakopoulos, Panagis
,
Conway, Stuart J
Published in
Journal of medicinal chemistry
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BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability
by
Jennings, Laura E.
,
Schiedel, Matthias
,
Hewings, David S.
,
Picaud, Sarah
,
Laurin, Corentine M.C.
,
Bruno, Paul A.
,
Bluck, Joseph P.
,
Scorah, Amy R.
,
See, Larissa
,
Reynolds, Jessica K.
,
Moroglu, Mustafa
,
Mistry, Ishna N.
,
Hicks, Amy
,
Guzanov, Pavel
,
Clayton, James
,
Evans, Charles N.G.
,
Stazi, Giulia
,
Biggin, Philip C.
,
Mapp, Anna K.
,
Hammond, Ester M.
,
Humphreys, Philip G.
,
Filippakopoulos, Panagis
,
Conway, Stuart J.
Published in
Bioorganic & medicinal chemistry
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Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33α and TRIM33β Bromodomains
by
Sekirnik, Angelina R.
,
Reynolds, Jessica K.
,
See, Larissa
,
Bluck, Joseph P.
,
Scorah, Amy R.
,
Tallant, Cynthia
,
Lee, Bernadette
,
Leszczynska, Katarzyna B.
,
Grimley, Rachel L.
,
Storer, R. Ian
,
Malattia, Marta
,
Crespillo, Sara
,
Caria, Sofia
,
Duclos, Stephanie
,
Hammond, Ester M.
,
Knapp, Stefan
,
Morris, Garrett M.
,
Duarte, Fernanda
,
Biggin, Philip C.
,
Conway, Stuart J.
Published in
ACS chemical biology
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Fragment-Based Identification of Ligands for Bromodomain-Containing Factor 3 of Trypanosoma cruzi
by
Laurin, Corentine M. C
,
Bluck, Joseph P
,
Chan, Anthony K. N
,
Keller, Michelle
,
Boczek, Andrew
,
Scorah, Amy R
,
See, K. F. Larissa
,
Jennings, Laura E
,
Hewings, David S
,
Woodhouse, Fern
,
Reynolds, Jessica K
,
Schiedel, Matthias
,
Humphreys, Philip G
,
Biggin, Philip C
,
Conway, Stuart J
Published in
ACS infectious diseases
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Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model
by
Lasagna-Reeves, Cristian A.
,
de Haro, Maria
,
Hao, Shuang
,
Park, Jeehye
,
Rousseaux, Maxime W.C.
,
Al-Ramahi, Ismael
,
Jafar-Nejad, Paymaan
,
Vilanova-Velez, Luis
,
See, Lauren
,
De Maio, Antonia
,
Nitschke, Larissa
,
Wu, Zhenyu
,
Troncoso, Juan C.
,
Westbrook, Thomas F.
,
Tang, Jianrong
,
Botas, Juan
,
Zoghbi, Huda Y.
Published in
Neuron (Cambridge, Mass.)
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