The Drosophila Pkn protein kinase is a Rho/Rac effector target required for dorsal closure during embryogenesis by Lu, Y, Settleman, J

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The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization by Vincent, Sylvie, Settleman, Jeffrey

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A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival by Singh, Anurag, Greninger, Patricia, Rhodes, Daniel, Koopman, Louise, Violette, Sheila, Bardeesy, Nabeel, Settleman, Jeff

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MC13-0075 Rapid assessment of TORC1 suppression as a functional biomarker predicting responsiveness to RAF and MEK inhibitors in BRAF-mutant melanoma patients by Corcoran, R.B, Rothenberg, M.S, Piris, A, Nazarian, R.M, Maheswaran, S, Settleman, J, Wargo, J.A, Flaherty, K.T, Haber, D.A, Engelman, J.A

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P190A RhoGAP is required for mammary gland development by Heckman-Stoddard, B.M., Vargo-Gogola, T., Herrick, M.P., Visbal, A.P., Lewis, M.T., Settleman, J., Rosen, J.M.

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GAP control: regulating the regulators of small GTPases by Bernards, Andre, Settleman, Jeffrey

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Identification of a human rasGAP-related protein containing calmodulin-binding motifs by WEISSBACH, L, SETTLEMAN, J, KALADY, M. F, SNIJDERS, A. J, MURTHY, A. E, YU-XIN YAN, BERNARDS, A

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149 Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS-mutant Cancer Models by Corcoran, R, Cheng, K, Hata, A, Faber, A, Singh, A, Settleman, J, Benes, C, Mino-Kenudson, M, Wong, K, Engelman, J

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Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation by Foster, Rosemary, Hu, Kang-Quan, Lu, Yu, Nolan, Katherine M., Thissen, Julia, Settleman, Jeffrey

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Gefitinib-Sensitizing EGFR Mutations in Lung Cancer Activate Anti-Apoptotic Pathways by Sordella, Raffaella, Bell, Daphne W., Haber, Daniel A., Settleman, Jeffrey

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Role of Prenylation in the Interaction of Rho-Family Small GTPases with GTPase Activating Proteins by Molnár, Gergely, Dagher, Marie-Claire, Geiszt, Miklós, Settleman, Jeffrey, Ligeti, Erzsébet

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Tension Precedes Commitment—Even for a Stem Cell by Settleman, Jeffrey

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Irreversible Inhibitors of the EGF Receptor May Circumvent Acquired Resistance to Gefitinib by Kwak, Eunice L., Sordella, Raffaella, Bell, Daphne W., Godin-Heymann, Nadia, Okimoto, Ross A., Brannigan, Brian W., Harris, Patricia L., Driscoll, David R., Fidias, Panos, Lynch, Thomas J., Rabindran, Sridhar K., McGinnis, John P., Wissner, Allan, Sharma, Sreenath V., Isselbacher, Kurt J., Settleman, Jeffrey, Haber, Daniel A.

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c-Src Regulates the Simultaneous Rearrangement of Actin Cytoskeleton, p190RhoGAP, and p120RasGAP Following Epidermal Growth Factor Stimulation by Chang, Jin-Hong, Gill, Satinder, Settleman, Jeffrey, Parsons, Sarah J.

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Rac 'n Rho: The Music that Shapes a Developing Embryo by Settleman, Jeffrey

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Amplification of MET May Identify a Subset of Cancers with Extreme Sensitivity to the Selective Tyrosine Kinase Inhibitor PHA-665752 by Smolen, Gromoslaw A., Sordella, Raffaella, Muir, Beth, Mohapatra, Gayatry, Barmettler, Anne, Archibald, Heidi, Kim, Woo J., Okimoto, Ross A., Bell, Daphne W., Sgroi, Dennis C., Christensen, James G., Settleman, Jeffrey, Haber, Daniel A.

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Modulation of Rho GTPase Signaling Regulates a Switch between Adipogenesis and Myogenesis by Sordella, Raffaella, Jiang, Wei, Chen, Guang-Chao, Curto, Marcello, Settleman, Jeffrey

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Rho family GTPases: more than simple switches by Symons, Marc, Settleman, Jeff

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Differing structural requirements for GTPase-activating protein responsiveness and NADPH oxidase activation by Rac by Xu, X, Barry, D C, Settleman, J, Schwartz, M A, Bokoch, G M

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Characterization of rho GTPase family homologues in Drosophila melanogaster: overexpressing Rho1 in retinal cells causes a late developmental defect by Hariharan, I.K., Hu, K.Q., Asha, H., Quintanilla, A., Ezzell, R.M., Settleman, J.

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