A CDK1 phosphorylation site on Drosophila PAR-3 regulates neuroblast polarisation and sensory organ formation by Loyer, Nicolas, Hogg, Elizabeth K J, Shaw, Hayley G, Pasztor, Anna, Murray, David H, Findlay, Greg M, Januschke, Jens

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Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score by Knight, Stephen R, Ho, Antonia, Pius, Riinu, Buchan, Iain, Carson, Gail, Drake, Thomas M, Dunning, Jake, Fairfield, Cameron J, Gamble, Carrol, Green, Christopher A, Gupta, Rishi, Halpin, Sophie, Hardwick, Hayley E, Holden, Karl A, Horby, Peter W, Jackson, Clare, Mclean, Kenneth A, Merson, Laura, Nguyen-Van-Tam, Jonathan S, Norman, Lisa, Noursadeghi, Mahdad, Olliaro, Piero L, Pritchard, Mark G, Russell, Clark D, Shaw, Catherine A, Sheikh, Aziz, Solomon, Tom, Sudlow, Cathie, Swann, Olivia V, Turtle, Lance CW, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G, Docherty, Annemarie B, Harrison, Ewen M

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The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer by Shaw, Greg L, Whitaker, Hayley, Corcoran, Marie, Dunning, Mark J, Luxton, Hayley, Kay, Jonathan, Massie, Charlie E, Miller, Jodi L, Lamb, Alastair D, Ross-Adams, Helen, Russell, Roslin, Nelson, Adam W, Eldridge, Matthew D, Lynch, Andrew G, Ramos-Montoya, Antonio, Mills, Ian G, Taylor, Angela E, Arlt, Wiebke, Shah, Nimish, Warren, Anne Y, Neal, David E

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Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study by Halpin, Sophie, Donohue, Chloe, Ladhani, Shamez, Horby, Peter W, Docherty, Annemarie B, Semple, Malcolm G, Openshaw, Peter J M, Bach, Benjamin, Chand, Meera, Harrison, Ewen M, Hiscox, Julian A, Horby, Peter W, Klenerman, Paul, Law, Andrew, Moore, Shona C, Palmarini, Massimo, Russell, Clark D, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Thomson, Emma C, Oosthuyzen, Wilna, Norman, Lisa, Pius, Riinu, Mclean, Kenneth A, Saviciute, Egle, Leeming, Gary, Hendry, Ross, Greenhalf, William, Ahmed, Katie A, Asiimwe, Innocent G, Brennan, Benjamin, Catterall, Benjamin WA, Clark, Jordan J, Cole, Sarah, Cox, Helen, Elliott, Angela, Foster, Terry, Greenhalf, Willliam, Jones, Trevor R, Murphy, Ellen G, Small, Benjamin, Subramaniam, Krishanthi S, Tanianis, Jolanta, Trochu, Erwan, van Tonder, Libby, Wilcock, Eve, Agranoff, Daniel, Angus, Brian, Atkinson, Dougal, Barlow, Gavin, Barrett, Nicholas, Bassford, Christopher, Beadsworth, Michael, Best, Nicola, Burden, Tom, Chukkambotla, Srikanth, Cupitt, Jason, Dark, Paul, Dushianthan, Ahilanadan, Dyer, Tristan, Evans, Cariad, Fegan, Christopher, Finn, Adam, Fullerton, Duncan, Goldsmith, Arthur, Hardy, Elaine, Havalda, Peter, Holme, Anita, Kendall, Jason, Kerrison, Caroline, Larkin, Susan, Leiner, Tamas, Lillie, Patrick, MacNaughton, Emily, McCullough, Katherine, Moore, Elinoor, Morgan, Patrick, Morris, Craig, Nelson, Mark, Panchatsharam, Selva, Pintus, Stefania, Prout, Rachel, Rousseau, Guy, Ryan, Brendan, Saluja, Taranprit, Shanmuga, Prad, Sharma, Anil, Sizer, Jeremy, Smith, Richard, Snelson, Catherine, Spittle, Nick, Stambach, Tom, Tridente, Ascanio, Ustianowski, Andrew, Waddy, Sam, Whittaker, Paul, Williams, Martin, Wiselka, Martin, Young, Peter

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Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease. An International Multicenter Study by Drake, Thomas M, Docherty, Annemarie B, Harrison, Ewen M, Quint, Jennifer K, Adamali, Huzaifa, Agnew, Sarah, Babu, Suresh, Barber, Christopher M, Barratt, Shaney, Bendstrup, Elisabeth, Bianchi, Stephen, Villegas, Diego Castillo, Chaudhuri, Nazia, Chua, Felix, Coker, Robina, Chang, William, Crawshaw, Anjali, Crowley, Louise E, Dosanjh, Davinder, Fiddler, Christine A, Forrest, Ian A, George, Peter M, Gibbons, Michael A, Groom, Katherine, Haney, Sarah, Hart, Simon P, Heiden, Emily, Henry, Michael, Ho, Ling-Pei, Hoyles, Rachel K, Hutchinson, John, Hurley, Killian, Jones, Mark, Jones, Steve, Kokosi, Maria, Kreuter, Michael, MacKay, Laura S, Mahendran, Siva, Margaritopoulos, George, Molina-Molina, Maria, Molyneaux, Philip L, O'Brien, Aiden, O'Reilly, Katherine, Packham, Alice, Parfrey, Helen, Poletti, Venerino, Porter, Joanna C, Renzoni, Elisabetta, Rivera-Ortega, Pilar, Russell, Anne-Marie, Saini, Gauri, Spencer, Lisa G, Stella, Giulia M, Stone, Helen, Sturney, Sharon, Thickett, David, Thillai, Muhunthan, Wallis, Tim, Ward, Katie, Wells, Athol U, West, Alex, Wickremasinghe, Melissa, Woodhead, Felix, Hearson, Glenn, Howard, Lucy, Baillie, J Kenneth, Openshaw, Peter J M, Semple, Malcolm G, Stewart, Iain, Jenkins, R Gisli

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SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses by Wang, Beibei, Skelly, Donal, Pan, Daniel, Omo-Dare, Nicola, Koeckerling, David, Jenkin, Daniel, Fernandes da Costa, Cristiano, Malik, Tariq, Baillie, J. Kenneth, Klenerman, Paul, Pollard, Andrew J., Conlon, Christopher, Jeffery, Katie, Stafford, Lizzie, Chand, Meera, Green, Christoper A., Harrison, Ewen M., Wai Ho, Antonia Ying, Palmarini, Massimo, Price, Nicholas, Robertson, David L., Sigfrid, Louise, Sriskandan, Shiranee, Stuart, David, Swann, Olivia V., Tedder, Richard S., Turtle, Lance CW, Zambon, Maria, Pius, Riinu, Knight, Stephen R., Harrison, Janet, Jackson, Clare, Gamble, Carrol, Plotkin, Daniel, Lee, James, Wham, Murray, Shaw, Victoria, McDonald, Sarah E., Armstrong, Jane A., Ashworth, Milton, Barlow, Samantha L., Bullock, Katie, Davis, Christopher, Dunn, Chris, King, Katharine, Kiy, Robyn T., Lant, Suzannah, Latawiec, Diane, Mancini, Maria, Metelmann, Soeren, Penrice-Randal, Rebekah, Pilgrim, Jack, van Tonder, Libby, Murphy, Lee, Morrice, Kirstie, Gilchrist, Tammy, Aldera, Erin L., Barnass, Stella, Bernatoniene, Jolanta, Bothma, Pieter, Brittain-Long, Robin, Caruth, Vikki, Collini, Paul, Dawson, Chris, Dervisevic, Samir, Dushianthan, Ahilanadan, Evans, Cariad, Harvey, Daniel, Hawcutt, Daniel B., Hodgson, Luke, Hormis, Anil, Kerrison, Caroline, Larkin, Susan, Little, Jeff, Meda, Manjula, Moon, James, Mortimore, Katherine, Murphy, Michael, O’Shea, Matthew K., Otahal, Igor, Panchatsharam, Selva, Patel, Brij, Pepperell, Justin, Peters, Mark, Price, David, Reschreiter, Henrik, Ruge, Bobby, Saluja, Taranprit, Sizer, Jeremy, Shankar-Hari, Manu, Snelson, Catherine, Staines, Nikki, Twagira, Mary, Vincent-Smith, Lisa, Visuvanathan, Shico, Welters, Ingeborg, Wolverson, Adam, Yates, Bryan, Fry, Elizabeth E., Ren, Jingshan

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Changes in hospital mortality in patients with cancer during the COVID-19 pandemic (ISARIC-CCP-UK): a prospective, multicentre cohort study by Turtle, Lance, Elliot, Sarah, Drake, Thomas M, Thorpe, Mathew, Khoury, Emma G, Greenhalf, William, Hardwick, Hayley E, Leeming, Gary, Law, Andy, Oosthuyzen, Wilna, Pius, Riinu, Shaw, Catherine A, Baillie, J Kenneth, Openshaw, Peter J M, Docherty, Annemarie B, Semple, Malcolm G, Harrison, Ewen M, Palmieri, Carlo

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Acute kidney injury in patients hospitalized with COVID-19 from the ISARIC WHO CCP-UK Study: a prospective, multicentre cohort study by Sullivan, Michael K, Lees, Jennifer S, Drake, Thomas M, Docherty, Annemarie B, Oates, Georgia, Hardwick, Hayley E, Russell, Clark D, Merson, Laura, Dunning, Jake, Nguyen-Van-Tam, Jonathan S, Openshaw, Peter, Harrison, Ewen M, Baillie, J Kenneth, Semple, Malcolm G, Ho, Antonia, Mark, Patrick B

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Vascular health years after a hypertensive disorder of pregnancy: The EPOCH study by Miller, Hayley E., Tierney, Seda, Stefanick, Marcia L., Mayo, Jonathan A., Sedan, Oshra, Rosas, Lisa G., Melbye, Mads, Boyd, Heather A., Stevenson, David K., Shaw, Gary M., Winn, Virginia D., Hlatky, Mark A.

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Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, pr... by Fairfield, Cameron J, Drake, Thomas M, Sigfrid, Louise, Docherty, Annemarie B, Girvan, Michelle, Dunning, Jake, Openshaw, Peter J M, Openshaw, Peter JM, Bach, Benjamin, Chand, Meera, Harrison, Ewen M, Hiscox, Julian A, Law, Andrew, Merson, Laura, Moore, Shona C, Russell, Clark D, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Tedder, Richard S, Palmieri, Carlo, Knight, Stephen R, Shaw, Catherine A, Marsh, Laura, Shaw, Victoria, McDonald, Sarah E, Keating, Seán, Armstrong, Jane A, Ashworth, Milton, Booth, Laura, Brennan, Benjamin, Bullock, Katie, Cooper, Louise, Davis, Christopher, Dincarslan, Oslem, Dunn, Chris, Evans, Anthony, Garcia-Dorival, Isabel, Jones, Christopher B, Khandaker, Shadia, Lant, Suzannah, Lavelle-Langham, Lara, Lefteri, Daniella, Lett, Lauren, Livoti, Lucia A, Mancini, Maria, McLauchlan, John, Murphy, Ellen G, Penrice-Randal, Rebekah, Pilgrim, Jack, Small, Benjamin, Subramaniam, Krishanthi S, Tanianis-Hughes, Jolanta, van Tonder, Libby, Wilcock, Eve, Flaherty, Lisa, MacLean, Alan, Agranoff, Daniel, Aldera, Erin L., Alegria, Ana, Bari, Shahedal, Barlow, Gavin, Barnass, Stella, Basude, Sneha, Chadwick, David, Chee, Nigel, Chukkambotla, Srikanth, Cutino-Moguel, Maria-Teresa, Dark, Paul, Donnison, Phil, Douthwaite, Sam, Dushianthan, Ahilanadan, Eziefula, Chi, Fegan, Chrisopher, Garg, Atul, Hawcutt, Daniel B, Hobrok, Maria, Jennings, Paul, Koduri, Gouri, Laha, Shondipon, Laird, Steven, MacNaughton, Emily, Mankregod, Ravish, Masson, Huw, McCullough, Katherine, Mirfenderesky, Mariyam, Mohandas, Kavya, Morris, Craig, Nagel, Megan, Papakonstantino, Danai, Pintus, Stefania, Singh Pooni, Jagtur, Prout, Rachel, Roberts, Devender, Rose, Alistair, Shawcross, Anna, Tatham, Kate, Vuylsteke, Alan, Whittaker, Paul, Wiselka, Martin

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A mixed methods study of Aboriginal health workers' and exercise physiologists' experiences of co-designing chronic lung disease 'yarning' education resources by Meharg, David P, Dennis, Sarah M, McNab, Justin, Gwynne, Kylie G, Jenkins, Christine R, Maguire, Graeme P, Jan, Stephen, Shaw, Tim, McKeough, Zoe, Rambaldini, Boe, Lee, Vanessa, McCowen, Debbie, Newman, Jamie, Monaghan, Scott, Longbottom, Hayley, Eades, Sandra J, Alison, Jennifer A

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Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19 by Thwaites, Ryan S, Sanchez Sevilla Uruchurtu, Ashley, Siggins, Matthew K, Liew, Felicity, Russell, Clark D, Moore, Shona C, Fairfield, Cameron, Carter, Edwin, Abrams, Simon, Short, Charlotte-Eve, Thaventhiran, Thilipan, Bergstrom, Emma, Gardener, Zoe, Ascough, Stephanie, Chiu, Christopher, Docherty, Annemarie B, Hunt, David, Crow, Yanick J, Solomon, Tom, Taylor, Graham P, Turtle, Lance, Harrison, Ewen M, Dunning, Jake, Semple, Malcolm G, Baillie, J Kenneth, Openshaw, Peter Jm

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Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial by Bath, Philip M, Cala, Lesley, Dixon, Mark, Mair, Grant, Potter, John, Roffe, Christine, Sandset, Else C, Sanossian, Nerses, Venables, Graham, Sprigg, Nikola, Amarenco, Pierre, Walker, Gemma, Gregory, Hayley, Smithson, Jennifer, Keeling, Joanne, Frowd, Nadia, Law, Zhe Kang, Payne, T, Spaight, R, Spaight, A, Whileman, A, Patel, C, Khan, S, Perkin, L, Arif, S, Sunman, W, Buck, A, Richardson, C, Constantin, C, Markova, S, Hedstrom, A, Keane, S, McKenzie, H, Mellows, K, Wyllie, H, Goffin, K, Ravenhill, G, Ford, L, Davison, W, Ho, C, McKenzie, E, Sylvester, N, Skene, I, Cuenoud, L, Daboo, P, Watchurst, C, Obarey, S, Pocock, H, Robinson, M, Oborn, M, Obeid, M, Whiting, R, Gagg, J, Hussain, M, Bagnall, C, Harrington, F, Nisbett, T, Jennings, G, Shaw, L, Worner, R, Saulat, A, Garfield-Smith, J, Haley, M, Rashed, K, Tanate, A, Wood, D, Matthews, L, Rees, N, Convery, C, Dixon, M, Davies, C, Chandler, A, Andrews, K, Horwood, P, Boldy, R, Jenkins, C, Price, F, Willberry, A, Alipio, F, Hiden, J, Varquez, R, Epstein, E, Hurdowar, S, Bellfield, R, Nair, A, Wilson, A, Gomes, P, Bwalya, A, Gillespie, A, Naylor, C, Clarkson, E, Finch, L, Datta, P, Needle, A, Walker, R, Murray, V, Ali, A, Kamara, C, Doyle, C, Willcoxson, P

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Frequent physical activity may not reduce vascular disease risk as much as moderate activity: large prospective study of women in the United Kingdom by Armstrong, Miranda E G, Green, Jane, Reeves, Gillian K, Beral, Valerie, Cairns, Benjamin J

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Obesity, Ethnicity, and Risk of Critical Care, Mechanical Ventilation, and Mortality in Patients Admitted to Hospital with COVID‐19: Analysis of the ISARIC CCP‐UK Cohort by Yates, Thomas, Zaccardi, Francesco, Islam, Nazrul, Razieh, Cameron, Gillies, Clare L., Lawson, Claire A., Chudasama, Yogini, Rowlands, Alex, Davies, Melanie J., Docherty, Annemarie B., Openshaw, Peter J. M., Baillie, J. Kenneth, Semple, Malcolm G., Khunti, Kamlesh

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The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection by Goldswain, Hannah, Dong, Xiaofeng, Penrice-Randal, Rebekah, Alruwaili, Muhannad, Shawli, Ghada T, Prince, Tessa, Williamson, Maia Kavanagh, Raghwani, Jayna, Randle, Nadine, Jones, Benjamin, Donovan-Banfield, I'ah, Salguero, Francisco J, Tree, Julia A, Hall, Yper, Hartley, Catherine, Erdmann, Maximilian, Bazire, James, Jearanaiwitayakul, Tuksin, Semple, Malcolm G, Openshaw, Peter J M, Baillie, J Kenneth, Emmett, Stevan R, Digard, Paul, Matthews, David A, Turtle, Lance, Darby, Alistair C, Davidson, Andrew D, Carroll, Miles W, Hiscox, Julian A

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Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020 by Thompson, Craig P, Grayson, Nicholas E, Paton, Robert S, Bolton, Jai S, Lourenço, José, Penman, Bridget S, Lee, Lian N, Odon, Valerie, Mongkolsapaya, Juthathip, Chinnakannan, Senthil, Dejnirattisai, Wanwisa, Edmans, Matthew, Fyfe, Alex, Imlach, Carol, Kooblall, Kreepa, Lim, Nicholas, Liu, Chang, López-Camacho, César, McInally, Carol, McNaughton, Anna L, Ramamurthy, Narayan, Ratcliff, Jeremy, Supasa, Piyada, Sampson, Oliver, Wang, Beibei, Mentzer, Alexander J, Turner, Marc, Semple, Malcolm G, Baillie, Kenneth, Harvala, Heli, Screaton, Gavin R, Temperton, Nigel, Klenerman, Paul, Jarvis, Lisa M, Gupta, Sunetra, Simmonds, Peter

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Abstract 12499: Anomalous Coronary Arteries Are Associated With Ischemia in the Ischemia Trial by Jaspan, Vita, Leipsic, Jonathon A, Nemeth, Hayley, Mancini, G B, Budoff, Matthew, Hague, Cameron, Min, James, Shaw, Leslee J, Berman, Daniel, Picard, Michael, Chaitman, Bernard R, Kwong, Raymond Y, OBrien, Sean, Hochman, Judith S, Maron, David J, Reynolds, Harmony

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A Qualitative Study of Aboriginal Peoples' Health Care Experiences With Chronic Obstructive Pulmonary Disease by Meharg, David P, Dennis, Sarah M, McNab, Justin, Gwynne, Kylie G, Jenkins, Christine R, Maguire, Graeme P, Jan, Stephen, Shaw, Tim, McKeough, Zoe, Rambaldini, Boe, Lee, Vanessa, McCowen, Debbie, Newman, Jamie, Longbottom, Hayley, Eades, Sandra, Alison, Jennifer A

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Quantifying neutralising antibody responses against SARS-CoV-2 in dried blood spots (DBS) and paired sera by Roper, Kelly J., Thomas, Jordan, Albalawi, Wejdan, Maddocks, Emily, Dobson, Susan, Alshehri, Abdullateef, Barone, Francesco G., Baltazar, Murielle, Semple, Malcolm G., Ho, Antonia, Turtle, Lance, Paxton, William A., Pollakis, Georgios

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