Natural Product Libraries to Accelerate the High-Throughput Discovery of Therapeutic Leads by Johnson, Tyler A, Sohn, Johann, Inman, Wayne D, Estee, Samarkand A, Loveridge, Steven T, Vervoort, Helene C, Tenney, Karen, Liu, Junke, Ang, Kenny Kean-Hooi, Ratnam, Joseline, Bray, Walter M, Gassner, Nadine C, Shen, Young Y, Lokey, R. Scott, McKerrow, James H, Boundy-Mills, Kyria, Nukanto, Arif, Kanti, Atit, Julistiono, Heddy, Kardono, Leonardus B. S, Bjeldanes, Leonard F, Crews, Phillip

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E7766, a Macrocycle‐Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan‐Genotypic Activity by Kim, Dae‐Shik, Endo, Atsushi, Fang, Francis G., Huang, Kuan‐Chun, Bao, Xingfeng, Choi, Hyeong‐wook, Majumder, Utpal, Shen, Young Y., Mathieu, Steven, Zhu, Xiaojie, Sanders, Kristen, Noland, Thomas, Hao, Ming‐Hong, Chen, Yu, Wang, John Y., Yasui, So, TenDyke, Karen, Wu, Jiayi, Ingersoll, Christy, Loiacono, Kara A., Hutz, Janna E., Sarwar, Nadeem

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Front Cover: E7766, a Macrocycle‐Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan‐Genotypic Activity (ChemMedChem 11/2021) by Kim, Dae‐Shik, Endo, Atsushi, Fang, Francis G., Huang, Kuan‐Chun, Bao, Xingfeng, Choi, Hyeong‐wook, Majumder, Utpal, Shen, Young Y., Mathieu, Steven, Zhu, Xiaojie, Sanders, Kristen, Noland, Thomas, Hao, Ming‐Hong, Chen, Yu, Wang, John Y., Yasui, So, TenDyke, Karen, Wu, Jiayi, Ingersoll, Christy, Loiacono, Kara A., Hutz, Janna E., Sarwar, Nadeem

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Sesquiterpenoids from myrrh inhibit androgen receptor expression and function in human prostate cancer cells by Wang, Xiao-ling, Kong, Feng, Shen, Tao, Young, Charles YF, Lou, Hong-xiang, Yuan, Hui-qing

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Nonoperative treatment Versus posterior fixation for thoracolumbar junction burst fractures without neurologic deficit by SHEN, Wun-Jer, LIU, Tsung-Jen, SHEN, Young-Shung

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Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium by Cai, Qiuyin, Long, Jirong, Lu, Wei, Qu, Shimian, Wen, Wanqing, Kang, Daehee, Lee, Ji-Young, Chen, Kexin, Shen, Hongbing, Shen, Chen-Yang, Sung, Hyuna, Matsuo, Keitaro, Haiman, Christopher A., Khoo, Ui Soon, Ren, Zefang, Iwasaki, Motoki, Gu, Kai, Xiang, Yong-Bing, Choi, Ji-Yeob, Park, Sue K., Zhang, Lina, Hu, Zhibin, Wu, Pei-Ei, Noh, Dong-Young, Tajima, Kazuo, Henderson, Brian E., Chan, Kelvin Y.K., Su, Fengxi, Kasuga, Yoshio, Wang, Wenjing, Cheng, Jia-Rong, Yoo, Keun-Young, Lee, Jong-Young, Zheng, Hong, Liu, Yao, Shieh, Ya-Lan, Kim, Sung-Won, Lee, Jong Won, Iwata, Hiroji, Le Marchand, Loic, Chan, Sum Yin, Xie, Xiaoming, Tsugane, Shoichiro, Lee, Min Hyuk, Wang, Shenming, Li, Guoliang, Levy, Shawn, Huang, Bo, Shi, Jiajun, Delahanty, Ryan, Zheng, Ying, Li, Chun, Gao, Yu-Tang, Shu, Xiao-Ou, Zheng, Wei

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Homologous Recombination Deficiency and Platinum-Based Therapy Outcomes in Advanced Breast Cancer by Zhao, Eric Y, Shen, Yaoqing, Pleasance, Erin, Kasaian, Katayoon, Leelakumari, Sreeja, Jones, Martin, Bose, Pinaki, Ch'ng, Carolyn, Reisle, Caralyn, Eirew, Peter, Corbett, Richard, Mungall, Karen L, Thiessen, Nina, Ma, Yussanne, Schein, Jacqueline E, Mungall, Andrew J, Zhao, Yongjun, Moore, Richard A, Den Brok, Wendie, Wilson, Sheridan, Villa, Diego, Shenkier, Tamara, Lohrisch, Caroline, Chia, Stephen, Yip, Stephen, Gelmon, Karen, Lim, Howard, Renouf, Daniel, Sun, Sophie, Schrader, Kasmintan A, Young, Sean, Bosdet, Ian, Karsan, Aly, Laskin, Janessa, Marra, Marco A, Jones, Steven J M

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White matter development and language abilities during infancy in autism spectrum disorder by McFayden, Tyler C., Rutsohn, Joshua, Cetin, Gizem, Forsen, Elizabeth, Swanson, Meghan R., Meera, Shoba S., Wolff, Jason J., Elison, Jed T., Shen, Mark D., Botteron, Kelly, Dager, Stephen R., Estes, Annette, Gerig, Guido, McKinstry, Robert C., Pandey, Juhi, Schultz, Robert, St. John, Tanya, Styner, Martin, Truong, Young, Zwaigenbaum, Lonnie, Hazlett, Heather C., Piven, Joseph, Girault, Jessica B.

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Energetic Electron Precipitation Driven by Electromagnetic Ion Cyclotron Waves from ELFIN’s Low Altitude Perspective by Angelopoulos, V., Zhang, X.-J., Artemyev, A. V., Mourenas, D., Tsai, E., Wilkins, C., Runov, A., Liu, J., Turner, D. L., Li, W., Khurana, K., Wirz, R. E., Sergeev, V. A., Meng, X., Wu, J., Hartinger, M. D., Raita, T., Shen, Y., An, X., Shi, X., Bashir, M. F., Shen, X., Gan, L., Qin, M., Capannolo, L., Ma, Q., Russell, C. L., Masongsong, E. V., Caron, R., He, I., Iglesias, L., Jha, S., King, J., Kumar, S., Le, K., Mao, J., McDermott, A., Nguyen, K., Norris, A., Palla, A., Roosnovo, A., Tam, J., Xie, E., Yap, R. C., Ye, S., Young, C., Adair, L. A., Shaffer, C., Chung, M., Cruce, P., Lawson, M., Leneman, D., Allen, M., Anderson, M., Arreola-Zamora, M., Artinger, J., Asher, J., Branchevsky, D., Cliffe, M., Colton, K., Costello, C., Depe, D., Domae, B. W., Eldin, S., Fitzgibbon, L., Flemming, A., Frederick, D. M., Gilbert, A., Hesford, B., Krieger, R., Lian, K., McKinney, E., Miller, J. P., Pedersen, C., Qu, Z., Rozario, R., Rubly, M., Seaton, R., Subramanian, A., Sundin, S. R., Tan, A., Thomlinson, D., Turner, W., Wing, G., Wong, C., Zarifian, A.

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Upregulation of Haploinsufficient Gene Expression in the Brain by Targeting a Long Non-coding RNA Improves Seizure Phenotype in a Model of Dravet Syndrome by Hsiao, J., Yuan, T.Y., Tsai, M.S., Lu, C.Y., Lin, Y.C., Lee, M.L., Lin, S.W., Chang, F.C., Liu Pimentel, H., Olive, C., Coito, C., Shen, G., Young, M., Thorne, T., Lawrence, M., Magistri, M., Faghihi, M.A., Khorkova, O., Wahlestedt, C.

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Surface-subsurface model intercomparison: A first set of benchmark results to diagnose integrated hydrology and feedbacks by Maxwell, Reed M., Putti, Mario, Meyerhoff, Steven, Delfs, Jens-Olaf, Ferguson, Ian M., Ivanov, Valeriy, Kim, Jongho, Kolditz, Olaf, Kollet, Stefan J., Kumar, Mukesh, Lopez, Sonya, Niu, Jie, Paniconi, Claudio, Park, Young-Jin, Phanikumar, Mantha S., Shen, Chaopeng, Sudicky, Edward A., Sulis, Mauro

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Pembrolizumab plus trastuzumab and chemotherapy for HER2-positive gastric or gastro-oesophageal junction adenocarcinoma: interim analyses from the phase 3 KEYNOTE-811 randomised pl... by Janjigian, Yelena Y, Kawazoe, Akihito, Bai, Yuxian, Xu, Jianming, Lonardi, Sara, Metges, Jean Phillipe, Yanez, Patricio, Wyrwicz, Lucjan S, Shen, Lin, Ostapenko, Yuriy, Bilici, Mehmet, Chung, Hyun Cheol, Shitara, Kohei, Qin, Shu-Kui, Van Cutsem, Eric, Tabernero, Josep, Li, Kan, Shih, Chie-Schin, Bhagia, Pooja, Rha, Sun Young

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Phosphate solubilizing bacteria from subtropical soil and their tricalcium phosphate solubilizing abilities by Chen, Y.P., Rekha, P.D., Arun, A.B., Shen, F.T., Lai, W.-A., Young, C.C.

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Advances in Geroscience: Impact on Healthspan and Chronic Disease by Burch, John B., Augustine, Alison Deckhut, Frieden, Leslie A., Hadley, Evan, Howcroft, T. Kevin, Johnson, Ron, Khalsa, Partap S., Kohanski, Ronald A., Li, Xiao Ling, Macchiarini, Francesca, Niederehe, George, Oh, Young S., Pawlyk, Aaron C., Rodriguez, Henry, Rowland, Julia H., Shen, Grace L., Sierra, Felipe, Wise, Bradley C.

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Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 by Lucchesi, Lydia R, Agrawal, Sutapa, Ahmadi, Alireza, Aichour, Amani Nidhal, Altirkawi, Khalid, Ariani, Filippo, Awasthi, Ashish, Badali, Hamid, Banstola, Amrit, Bärnighausen, Till Winfried, Behzadifar, Meysam, Bensenor, Isabela M, Berhane, Adugnaw, Bhalla, Ashish, Bhaumik, Soumyadeeep, Bhutta, Zulfiqar A, Bijani, Ali, Bililign, Nigus, Birungi, Charles, Brown, Allen W, Carvalho, Félix, Catalá-López, Ferrán, Chaiah, Yazan, Chang, Jung-Chen, Choi, Jee-Young J, Crowe, Christopher Stephen, Daryani, Ahmad, Demoz, Gebre Teklemariam, Deribe, Kebede, Do, Huyen Phuc, Drake, Thomas M, Dubljanin, Eleonora, Fereshtehnejad, Seyed-Mohammad, Filip, Irina, Gankpe, Fortune Gbetoho, Gebrehiwot, Tsegaye Tewelde, Hamidi, Samer, Haro, Josep Maria, Hassen, Hamid Yimam, Hawley, Caitlin, Hendrie, Delia, Hole, Michael K, Homaie Rad, Enayatollah, Hostiuc, Sorin, Irvani, Seyed Sina Naghibi, Jakovljevic, Mihajlo, Khan, Ejaz Ahmad, Kim, Daniel, Kumar, G Anil, Lami, Faris Hasan, Leshargie, Cheru Tesema, Liben, Misgan Legesse, Lotufo, Paulo A, Mahotra, Narayan Bahadur, Majeed, Azeem, Mate, Kedar K V, Meles, Hagazi, Miller, Ted R, Mohammadi, Moslem, Mohammed, Shafiu, Mokdad, Ali H, Moradi-Lakeh, Maziar, Mustafa, Ghulam, Naghavi, Mohsen, Nyasulu, Peter S, Olivares, Pedro R, Owolabi, Mayowa Ojo, Polinder, Suzanne, Qorbani, Mostafa, Rafiei, Alireza, Rahimi-Movaghar, Afarin, Rai, Rajesh Kumar, Ram, Usha, Rawaf, David Laith, Ruhago, George Mugambage, Safari, Hosein, Saldanha, Raphael de Freitas, Samy, Abdallah M, Santric Milicevic, Milena M M, Shabaninejad, Hosein, Shaikh, Masood A Ali, She, Jun, Shiferaw, Mekonnen Sisay, Shiue, Ivy, Siddiqi, Tariq J, Silva, João Pedro, Soares Filho, Adauto Martins, Soofi, Moslem, Soriano, Joan B, Szoeke, Cassandra E I, Tekle, Merhawi Gebremedhin, Temsah, Omar, Uthman, Olalekan A, Violante, Francesco S, Weldegwergs, Kidu Gidey, Werdecker, Andrea, Yoon, Seok-Jun, Zenebe, Zerihun Menlkalew, Feigin, Valery L, Vos, Theo

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First-Line Catheter Ablation of Monomorphic Ventricular Tachycardia in Cardiomyopathy Concurrent With Defibrillator Implantation: The PAUSE-SCD Randomized Trial by Tung, Roderick, Xue, Yumei, Chen, Minglong, Jiang, Chenyang, Shatz, Dalise Y., Besser, Stephanie A., Hu, Hongde, Chung, Fa-Po, Nakahara, Shiro, Kim, Young-Hoon, Satomi, Kazuhiro, Shen, Lishui, Liang, Er’peng, Liao, Hongtao, Gu, Kai, Jiang, Ruhong, Jiang, Jian, Hori, Yuichi, Choi, Jong-Il, Ueda, Akiko, Komatsu, Yuki, Kazawa, Shuichiro, Soejima, Kyoko, Chen, Shih-Ann, Nogami, Akihiko, Yao, Yan

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Nonsurgical treatment of three-column thoracolumbar junction burst fractures without neurologic deficit by SHEN, W.-J, SHEN, Y.-S

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Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th... by Steinmetz, Jaimie D, Abrha, Woldu Aberhe, Abualhasan, Ahmed, Abu-Gharbieh, Eman Girum, Ahmadieh, Hamid, Alfaar, Ahmed Samir, Alipour, Vahid, Arabloo, Jalal, Aregawi, Brhane Berhe, Arrigo, Alessandro, Atnafu, Desta Debalkie, Baig, Atif Amin Winfried, Bärnighausen, Till Winfried, Battaglia Parodi, Maurizio, Beheshti, Mahya Srikanth, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bottone, Michele, Braithwaite, Tasanee M, Burugina Nagaraja, Sharath A, Butt, Zahid A, Casson, Robert James, Cheng, Ching-Yu Jasmine, Cicinelli, Maria Vittoria M, Congdon, Nathan G A, Cromwell, Elizabeth A M, Dahlawi, Saad M, Dana, Reza, Del Monte, Monte A, Derbew Molla, Meseret, Dervenis, Nikolaos Alemayehu, Djalalinia, Shirin E, Emamian, Mohammad Hassan, Eskandarieh, Sharareh, Farzadfar, Farshad G, Fischer, Florian S, Friedman, David S M, Furtado, João M, Gaidhane, Shilpa, George, Ronnie, Ghashghaee, Ahmad, Hamidi, Samer Randall, Hammond, Billy Randall R, Hartnett, Mary Elizabeth R Kusuma, Hartono, Risky Kusuma, Hashi, Abdiwahab I, Hay, Simon I, Heidari, Golnaz, Ho, Hung Chak, Huang, John J Emmanuel, Ibitoye, Segun Emmanuel M, Ilic, Irena M D, Kempen, John H, Khairallah, Moncef, Khalilov, Rovshan Ahmad, Kim, Yun Jin, Kosen, Soewarta, Kurmi, Om P, Landires, Iván Charles, Lansingh, Van Charles L, Leasher, Janet L E, Limburg, Hans, Meles, Gebrekiros Gebremichael M, Miller, Ted R, Mohammad, Yousef, Mohammadi, Seyed Farzad Abdu, Moni, Mohammad Ali Al, Mulaw, Getahun Fentaw C, Naimzada, Mukhammad David, Nangia, Vinay, Negash, Hadush Lan, Nguyen, Huong Lan, Onwujekwe, Obinna E, Pakshir, Keyvan, Panda-Jonas, Songhomitra, Park, Eun-Cheol, Peto, Tunde Quang, Pinheiro, Marina, Rahimi-Movaghar, Vafa, Rahman, Mohammad Hifz Ur Y, Ramulu, Pradeep Y, Renzaho, Andre M, Safi, Sare, Sahraian, Mohammad Ali M, Shaheen, Amira A Ali, Shibuya, Kenji Shibabaw, Shiferaw, Wondimeneh Shibabaw, Singh, Jasvinder A, Sitorus, Rita S, Skryabin, Valentin Yurievich Aleksandrovna, Soheili, Amin Bekele, Sreeramareddy, Chandrashekhar T, Tran, Bach Xuan, Tsegaye, Gebiyaw K, Tsilimbaris, Miltiadis K, Weldemariam, Abrha Hailay K, Wong, Tien Y, Yu, Chuanhua Sergeevich, Zimsen, Stephanie R, Vos, Theo

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Development of Older Adult Food Insecurity Index to Assess Food Insecurity of Older Adults by Lee, Jenny Jin Young, Shen, S., Nishita, C.

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LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers by Yu, Haiyang, Yue, Xuetian, Zhao, Yuhan, Li, Xiaoyan, Wu, Lihua, Zhang, Cen, Liu, Zhen, Lin, Kevin, Xu-Monette, Zijun Y., Young, Ken H., Liu, Juan, Shen, Zhiyuan, Feng, Zhaohui, Hu, Wenwei

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