A Practical Use of Ligand Efficiency Indices Out of the Fragment-Based Approach: Ligand Efficiency-Guided Lead Identification of Soluble Epoxide Hydrolase Inhibitors by Tanaka, Daisuke, Tsuda, Yusuke, Shiyama, Takaaki, Nishimura, Tamiki, Chiyo, Naoki, Tominaga, Yukio, Sawada, Nobuyuki, Mimoto, Tsutomu, Kusunose, Naoto

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Isolating the whole complex of target proteins of FK506 using affinity resins from novel solid phases by Takahashi, Teruki, Shiyama, Takaaki, Mori, Tomoko, Hosoya, Ken, Tanaka, Akito

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Design and synthesis of novel hydrophilic spacers for the reduction of nonspecific binding proteins on affinity resins by Shiyama, Takaaki, Furuya, Minoru, Yamazaki, Akira, Terada, Tomohiro, Tanaka, Akito

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An easy preparation of ‘monolithic type’ hydrophilic solid phase: Capability for affinity resin to isolate target proteins by Mori, Tomoko, Takahashi, Teruki, Shiyama, Takaaki, Tanaka, Akito, Hira, Natsuki, Tanaka, Nobuo, Hosoya, Ken

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Development of chemically stable solid phases for the target isolation with reduced nonspecific binding proteins by Takahashi, Teruki, Shiyama, Takaaki, Hosoya, Ken, Tanaka, Akito

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Synthesis and biological activity of a model disaccharide containing a key unit in heparin for binding to platelets by Suda, Yasuo, Bird, Karyn, Shiyama, Takaaki, Koshida, Shuhei, Marques, Dalila, Fukase, Koichi, Sobel, Michael, Kusumoto, Shoichi

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Discovery of hydroxamic acid analogs as dual inhibitors of phosphodiesterase-1 and -5 by Dan, Akihito, Shiyama, Takaaki, Yamazaki, Kazuto, Kusunose, Naoto, Fujita, Katsuya, Sato, Hideshi, Matsui, Kazutaka, Kitano, Masafumi

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Macrophage Activation in Response to S-Form Lipopolysaccharides (LPS) Separated by Centrifugal Partition Chromatography from Wild-Type LPS: Effects of the O-Polysaccharide Portion... by Suda, Y., Kirikae, T., Shiyama, T., Yasukochi, T., Kirikae, F., Nakano, M., Rietschel, E.T., Kusumoto, S.

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