Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities by Ali, Ahmed M., Gómez-Biagi, Rodolfo F., Rosa, David A., Lai, Ping-Shan, Heaton, William L., Park, Ji Sung, Eiring, Anna M., Vellore, Nadeem A., de Araujo, Elvin D., Ball, Dan P., Shouksmith, Andrew E., Patel, Ami B., Deininger, Michael W., O'Hare, Thomas, Gunning, Patrick T.

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PTG-0861: A novel HDAC6-selective inhibitor as a therapeutic strategy in acute myeloid leukaemia by Gawel, Justyna M., Shouksmith, Andrew E., Raouf, Yasir S., Nawar, Nabanita, Toutah, Krimo, Bukhari, Shazreh, Manaswiyoungkul, Pimyupa, Olaoye, Olasunkanmi O., Israelian, Johan, Radu, Tudor B., Cabral, Aaron D., Sina, Diana, Sedighi, Abootaleb, de Araujo, Elvin D., Gunning, Patrick T.

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Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T‑Cell Prolymphocytic Leukemia by Toutah, Krimo, Nawar, Nabanita, Timonen, Sanna, Sorger, Helena, Raouf, Yasir S, Bukhari, Shazreh, von Jan, Jana, Ianevski, Aleksandr, Gawel, Justyna M, Olaoye, Olasunkanmi O, Geletu, Mulu, Abdeldayem, Ayah, Israelian, Johan, Radu, Tudor B, Sedighi, Abootaleb, Bhatti, Muzaffar N, Hassan, Muhammad Murtaza, Manaswiyoungkul, Pimyupa, Shouksmith, Andrew E, Neubauer, Heidi A, de Araujo, Elvin D, Aittokallio, Tero, Krämer, Oliver H, Moriggl, Richard, Mustjoki, Satu, Herling, Marco, Gunning, Patrick T

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Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer by Shouksmith, Andrew E, Shah, Fenil, Grimard, Michelle L, Gawel, Justyna M, Raouf, Yasir S, Geletu, Mulu, Berger-Becvar, Angelika, de Araujo, Elvin D, Luchman, H. Artee, Heaton, William L, Bakhshinyan, David, Adile, Ashley A, Venugopal, Chitra, O’Hare, Thomas, Deininger, Michael W, Singh, Sheila K, Konieczny, Stephen F, Weiss, Samuel, Fishel, Melissa L, Gunning, Patrick T

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Unique Molecular Interaction with the Histone Deacetylase 6 Catalytic Tunnel: Crystallographic and Biological Characterization of a Model Chemotype by Olaoye, Olasunkanmi O, Watson, Paris R, Nawar, Nabanita, Geletu, Mulu, Sedighi, Abootaleb, Bukhari, Shazreh, Raouf, Yasir S, Manaswiyoungkul, Pimyupa, Erdogan, Fettah, Abdeldayem, Ayah, Cabral, Aaron D, Hassan, Muhammad Murtaza, Toutah, Krimo, Shouksmith, Andrew E, Gawel, Justyna M, Israelian, Johan, Radu, Tudor B, Kachhiyapatel, Niyati, de Araujo, Elvin D, Christianson, David W, Gunning, Patrick T

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Class I/IIb-Selective HDAC Inhibitor Exhibits Oral Bioavailability and Therapeutic Efficacy in Acute Myeloid Leukemia by Shouksmith, Andrew E, Gawel, Justyna M, Nawar, Nabanita, Sina, Diana, Raouf, Yasir S, Bukhari, Shazreh, He, Liying, Johns, Alexandra E, Manaswiyoungkul, Pimyupa, Olaoye, Olasunkanmi O, Cabral, Aaron D, Sedighi, Abootaleb, de Araujo, Elvin D, Gunning, Patrick T

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Identification of Bidentate Salicylic Acid Inhibitors of PTP1B by Haftchenary, Sina, Jouk, Andriana O, Aubry, Isabelle, Lewis, Andrew M, Landry, Melissa, Ball, Daniel P, Shouksmith, Andrew E, Collins, Catherine V, Tremblay, Michel L, Gunning, Patrick T

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Inside Cover: Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities (ChemMedC... by Ali, Ahmed M., Gómez-Biagi, Rodolfo F., Rosa, David A., Lai, Ping-Shan, Heaton, William L., Park, Ji Sung, Eiring, Anna M., Vellore, Nadeem A., de Araujo, Elvin D., Ball, Dan P., Shouksmith, Andrew E., Patel, Ami B., Deininger, Michael W., O'Hare, Thomas, Gunning, Patrick T.

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