Global, regional, and national burden of motor neuron diseases 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 by Logroscino, Giancarlo, Piccininni, Marco, Marin, Benoît, Nichols, Emma, Abd-Allah, Foad, Abdelalim, Ahmed, Alahdab, Fares, Asgedom, Solomon Weldegebreal, Awasthi, Ashish, Chaiah, Yazan, Daryani, Ahmad, Do, Huyen Phuc, Dubey, Manisha, Elbaz, Alexis, Eskandarieh, Sharareh, Farhadi, Farzaneh, Farzadfar, Farshad, Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Filip, Irina, Foreman, Kyle J., Gebre, Abadi Kahsu, Gnedovskaya, Elena V., Hamidi, Samer, Hay, Simon I., Irvani, Seyed Sina Naghibi, Ji, John S., Kasaeian, Amir, Kim, Yun Jin, Mantovani, Lorenzo Giovanni, Mashamba-Thompson, Tivani Phosa, Mehndiratta, Man Mohan, Mokdad, Ali H., Nagel, Gabriele, Nguyen, Trang Huyen, Nixon, Molly R, Olagunju, Andrew T, Owolabi, Mayowa Ojo, Piradov, Michael A, Qorbani, Mostafa, Radfar, Amir, Reiner, Robert C, Sahraian, Mohammad Ali, Sarvi, Shahabeddin, Sharif, Mehdi, Temsah, Omar, Tran, Bach Xuan, Truong, Nu Thi, Venketasubramanian, Narayanaswamy, Winkler, Andrea Sylvia, Yimer, Ebrahim M, Feigin, Valery L., Vos, Theo, Murray, Christopher J L

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Anti-TNF Therapeutic Drug Monitoring in Postoperative Crohn’s Disease by Wright, Emily K, Kamm, Michael A, De Cruz, Peter, Hamilton, Amy L, Selvaraj, Fabiyola, Princen, Fred, Gorelik, Alexandra, Liew, Danny, Prideaux, Lani, Lawrance, Ian C, Andrews, Jane M, Bampton, Peter A, Jakobovits, Simon L, Florin, Timothy H, Gibson, Peter R, Debinski, Henry, Macrae, Finlay A, Samuel, Douglas, Kronborg, Ian, Radford-Smith, Graham, Gearry, Richard B, Selby, Warwick, Bell, Sally J, Brown, Steven J, Connell, William R

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Distinct components of cardiovascular health are linked with age-related differences in cognitive abilities by King, Deborah L. O., Henson, Richard N., Kievit, Rogier, Wolpe, Noham, Brayne, Carol, Tyler, Lorraine K., Rowe, James B., Tsvetanov, Kamen A.

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A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns by Jiao, Wei, Atwal, Gurnit, Polak, Paz, Karlic, Rosa, Cuppen, Edwin, Danyi, Alexandra, de Ridder, Jeroen, van Herpen, Carla, Lolkema, Martijn P., Steeghs, Neeltje, Getz, Gad, Morris, Quaid D., Stein, Lincoln D.

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Age-related reduction in motor adaptation: brain structural correlates and the role of explicit memory by Wolpe, Noham, Ingram, James N., Tsvetanov, Kamen A., Henson, Richard N., Wolpert, Daniel M., Tyler, Lorraine K., Brayne, Carol, Bullmore, Edward T., Calder, Andrew C., Cusack, Rhodri, Dalgleish, Tim, Duncan, John, Matthews, Fiona E., Marslen-Wilson, William D., Shafto, Meredith A., Campbell, Karen, Cheung, Teresa, Davis, Simon, Geerligs, Linda, Kievit, Rogier, McCarrey, Anna, Mustafa, Abdur, Price, Darren, Samu, David, Taylor, Jason R., Treder, Matthias, van Belle, Janna, Williams, Nitin, Bates, Lauren, Emery, Tina, Erzinçlioglu, Sharon, Gadie, Andrew, Gerbase, Sofia, Georgieva, Stanimira, Hanley, Claire, Parkin, Beth, Troy, David, Auer, Tibor, Correia, Marta, Gao, Lu, Green, Emma, Henriques, Rafael, Allen, Jodie, Amery, Gillian, Amunts, Liana, Barcroft, Anne, Castle, Amanda, Dias, Cheryl, Dowrick, Jonathan, Fair, Melissa, Fisher, Hayley, Goulding, Anna, Grewal, Adarsh, Hale, Geoff, Hilton, Andrew, Johnson, Frances, Johnston, Patricia, Kavanagh-Williamson, Thea, Kwasniewska, Magdalena, McMinn, Alison, Norman, Kim, Penrose, Jessica, Roby, Fiona, Rowland, Diane, Sargeant, John, Squire, Maggie, Stevens, Beth, Stoddart, Aldabra, Stone, Cheryl, Thompson, Tracy, Yazlik, Ozlem, Barnes, Dan, Dixon, Marie, Hillman, Jaya, Mitchell, Joanne, Villis, Laura, Rowe, James B.

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Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children by Herberg, Jethro A, Kaforou, Myrsini, Wright, Victoria J, Shailes, Hannah, Eleftherohorinou, Hariklia, Hoggart, Clive J, Cebey-López, Miriam, Carter, Michael J, Janes, Victoria A, Gormley, Stuart, Shimizu, Chisato, Tremoulet, Adriana H, Barendregt, Anouk M, Salas, Antonio, Kanegaye, John, Pollard, Andrew J, Faust, Saul N, Patel, Sanjay, Kuijpers, Taco, Martinón-Torres, Federico, Burns, Jane C, Coin, Lachlan J. M, Levin, Michael

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Multiple determinants of lifespan memory differences by Henson, Richard N., Campbell, Karen L., Davis, Simon W., Taylor, Jason R., Emery, Tina, Erzinclioglu, Sharon, Kievit, Rogier A.

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An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expression by Cano-Gamez, Eddie, Burnham, Katie L, Goh, Cyndi, Allcock, Alice, Malick, Zunaira H, Overend, Lauren, Kwok, Andrew, Smith, David A, Peters-Sengers, Hessel, Antcliffe, David, McKechnie, Stuart, Scicluna, Brendon P, van der Poll, Tom, Gordon, Anthony C, Hinds, Charles J, Davenport, Emma E, Knight, Julian C, Webster, Nigel, Galley, Helen, Taylor, Jane, Hall, Sally, Addison, Jenni, Roughton, Sian, Tennant, Heather, Guleri, Achyut, Waddington, Natalia, Arawwawala, Dilshan, Durcan, John, Short, Alasdair, Swan, Karen, Williams, Sarah, Smolen, Susan, Mitchell-Inwang, Christine, Gordon, Tony, Errington, Emily, Templeton, Maie, Venatesh, Pyda, Ward, Geraldine, McCauley, Marie, Baudouin, Simon, Higham, Charley, Soar, Jasmeet, Grier, Sally, Hall, Elaine, Brett, Stephen, Kitson, David, Wilson, Robert, Mountford, Laura, Moreno, Juan, Hall, Peter, Hewlett, Jackie, McKechnie, Stuart, Garrard, Christopher, Millo, Julian, Young, Duncan, Hutton, Paula, Parsons, Penny, Smiths, Alex, Faras-Arraya, Roser, Raymode, Parizade, Thompson, Jonathan, Bowrey, Sarah, Kazembe, Sandra, Rich, Natalie, Andreou, Prem, Hales, Dawn, Roberts, Emma, Fletcher, Simon, Rosbergen, Melissa, Glister, Georgina, Cuesta, Jeronimo Moreno, Bion, Julian, Millar, Joanne, Perry, Elsa Jane, Willis, Heather, Mitchell, Natalie, Ruel, Sebastian, Carrera, Ronald, Wilde, Jude, Nilson, Annette, Lees, Sarah, Kapila, Atul, Jacques, Nicola, Atkinson, Jane, Brown, Abby, Prowse, Heather, Krige, Anton, Bland, Martin, Bullock, Lynne, Harrison, Donna, Mills, Gary, Humphreys, John, Armitage, Kelsey, Laha, Shond, Baldwin, Jacqueline, Walsh, Angela, Doherty, Nicola, Drage, Stephen, Ortiz-Ruiz de Gordoa, Laura

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High-throughput mass spectrometry maps the sepsis plasma proteome and differences in patient response by Mi, Yuxin, Burnham, Katie L, Charles, Philip D, Heilig, Raphael, Vendrell, Iolanda, Whalley, Justin, Torrance, Hew D, Antcliffe, David B, May, Shaun M, Neville, Matt J, Berridge, Georgina, Hutton, Paula, Geoghegan, Cyndi G, Radhakrishnan, Jayachandran, Nesvizhskii, Alexey I, Yu, Fengchao, Davenport, Emma E, McKechnie, Stuart, Davies, Roger, O'Callaghan, David J P, Patel, Parind, Del Arroyo, Ana G, Karpe, Fredrik, Gordon, Anthony C, Ackland, Gareth L, Hinds, Charles J, Fischer, Roman, Knight, Julian C

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Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris by Navarini, Alexander A., Simpson, Michael A., Weale, Michael, Knight, Jo, Carlavan, Isabelle, Reiniche, Pascale, Burden, David A., Layton, Alison, Bataille, Veronique, Allen, Michael, Pleass, Robert, Pink, Andrew, Creamer, Daniel, English, John, Munn, Stephanie, Walton, Shernaz, Willis, Carolyn, Déret, Sophie, Voegel, Johannes J., Spector, Tim, Smith, Catherine H., Trembath, Richard C., Barker, Jonathan N.

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Aromatase inhibitors versus tamoxifen in premenopausal women with oestrogen receptor-positive early-stage breast cancer treated with ovarian suppression: a patient-level meta-analy... by Bradley, Rosie, Braybrooke, Jeremy, Gray, Richard, Hills, Robert K, Liu, Zulian, Pan, Hongchao, Peto, Richard, Dodwell, David, McGale, Paul, Taylor, Carolyn, Francis, Prudence A, Gnant, Michael, Perrone, Francesco, Regan, Meredith M, Berry, Richard, Boddington, Clare, Clarke, Mike, Davies, Christina, Davies, Lucy, Duane, Fran, Evans, Vaughan, Gay, Jo, Gettins, Lucy, Godwin, Jon, James, Sam, Liu, Hui, MacKinnon, Elizabeth, Mannu, Gurdeep, McHugh, Theresa, Morris, Philip, Read, Simon, Straiton, Ewan, Jakesz, Raimund, Fesl, Christian, Pagani, Olivia, Gelber, Richard, De Laurentiis, Michelino, De Placido, Sabino, Gallo, Ciro, Albain, Kathy, Anderson, Stewart, Arriagada, Rodrigo, Bartlett, John, Bergsten-Nordström, Elizabeth, Bliss, Judith, Brain, Etienne, Carey, Lisa, Coleman, Robert, Cuzick, Jack, Davidson, Nancy, Del Mastro, Lucia, Di Leo, Angelo, Dignam, James, Dowsett, Mitch, Ejlertsen, Bent, Goetz, Matthew, Goodwin, Pam, Halpin-Murphy, Pat, Hayes, Dan, Hill, Catherine, Jagsi, Reshma, Janni, Wolfgang, Loibl, Sibylle, Mamounas, Eleftherios P, Martín, Miguel, Mukai, Hirofumi, Nekljudova, Valentina, Norton, Larry, Ohashi, Yasuo, Pierce, Lori, Poortmans, Philip, Pritchard, Kathleen I, Raina, Vinod, Rea, Daniel, Robertson, John, Rutgers, Emiel, Spanic, Tanja, Sparano, Joseph, Steger, Guenther, Tang, Gong, Toi, Masakazu, Tutt, Andrew, Viale, Giuseppe, Wang, Xiang, Whelan, Tim, Wilcken, Nicholas, Wolmark, Norman, Cameron, David, Bergh, Jonas, Swain, Sandra M

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Indomethacin with or without prophylactic pancreatic stent placement to prevent pancreatitis after ERCP: a randomised non-inferiority trial by Elmunzer, B Joseph, Foster, Lydia D, Serrano, Jose, Coté, Gregory A, Shah, Raj, Bang, Ji Young, Kwon, Richard S, Scheiman, James M, Willingham, Field F, Keilin, Steven A, Papachristou, Georgios I, Chak, Amitabh, Slivka, Adam, Mullady, Daniel, Kushnir, Vladimir, Buxbaum, James, Keswani, Rajesh, Forbes, Nauzer, Rastogi, Amit, Ross, Andrew, Law, Joanna, Barkun, Alan, Smith, Zachary L, Petersen, Bret, Wang, Andrew Y, Saltzman, John R, Spitzer, Rebecca L, Ordiah, Collins, Durkalski-Mauldin, Valerie, Elmunzer, B. Joseph, Foster, Lydia D., Coté, Gregory A., Edmundowicz, Steven A., Wani, Sachin, Shah, Raj, Bang, Ji Young, Singh, Vikesh K., Kwon, Richard S., Scheiman, James M., Willingham, Field F., Keilin, Steven A., Papachristou, Georgios I., Chak, Amitabh, Mullady, Daniel, Kushnir, Vladimir, Buxbaum, James, Keswani, Rajesh, Gardner, Timothy B., Forbes, Nauzer, Rastogi, Amit, Ross, Andrew, Law, Joanna, Yachimski, Patrick, Chen, Yen-I, Barkun, Alan, Smith, Zachary L., Petersen, Bret, Wang, Andrew Y., Saltzman, John R., Spitzer, Rebecca L., Ordiah, Collins, Spino, Cathie, Higgins, Peter D.R., Forster, Erin, Brauer, Brian, Wamsteker, Erik J., Cai, Qiang, Qayed, Emad, Groce, Royce, Krishna, Somashekar G., Glessing, Brooke, Rabinovitz, Mordechai, Lang, Gabriel, Aadam, Aziz, Komanduri, Srinadh, Adler, Jefferey, Gordon, Stuart, Mohamed, Rachid, Olyaee, Mojtaba, Depue Brewbaker, Emily K., Gould, Mariana, Olsen, Jama, Simon, Violette C., Kamal, Ayesha, Volk, Sarah L., Merchant, Ambreen A., Lahooti, Ali, Anderson, Gulsum, Hollander, Thomas, Vazquez, Alejandro, Li, Thomas Y., Hadley, Steven M., Chau, Millie, Mendoza, Robinson, Tangwongchai, Tida, Koza, Casey L., Geraci, Olivia, Nunez, Lizbeth, Waters, Alexander M., Durkalski-Mauldin, Valerie

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Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study by Bancroft, Elizabeth K, Page, Elizabeth C, Castro, Elena, Lilja, Hans, Vickers, Andrew, Sjoberg, Daniel, Assel, Melissa, Foster, Christopher S, Drew, Kate, Mæhle, Lovise, Axcrona, Karol, Evans, D. Gareth, Bulman, Barbara, Eccles, Diana, van Asperen, Christi, Vasen, Hans, Kiemeney, Lambertus A, Ringelberg, Janneke, Cybulski, Cezary, Wokolorczyk, Dominika, Selkirk, Christina, Hulick, Peter J, Bojesen, Anders, Skytte, Anne-Bine, Lam, Jimmy, Taylor, Louise, Oldenburg, Rogier, Verhaegh, Gerald, van Zelst-Stams, Wendy A, Oosterwijk, Jan C, Blanco, Ignacio, Salinas, Monica, Cook, Jackie, Rosario, Derek J, Buys, Saundra, Conner, Tom, Ausems, Margreet G, Ong, Kai-ren, Hoffman, Jonathan, Domchek, Susan, Teixeira, Manuel R, Maia, Sofia, Foulkes, William D, Taherian, Nassim, Ruijs, Marielle, den Enden, Apollonia T. Helderman-van, Izatt, Louise, Davidson, Rosemarie, Adank, Muriel A, Walker, Lisa, Schmutzler, Rita, Tucker, Kathy, Kirk, Judy, Hodgson, Shirley, Harris, Marion, Douglas, Fiona, Lindeman, Geoffrey J, Zgajnar, Janez, Tischkowitz, Marc, Susman, Rachel, Ramón y Cajal, Teresa, Patcher, Nicholas, Spigelman, Allan, Liljegren, Annelie, Side, Lucy, Brewer, Carole, Donaldson, Alan, Stefansdottir, Vigdis, Chen-Shtoyerman, Rakefet, Amor, David J, Barwell, Julian, Giri, Veda N, Murthy, Vedang, Nicolai, Nicola, Teo, Soo-Hwang, Greenhalgh, Lynn, Strom, Sara, Henderson, Alex, McGrath, John, Gallagher, David, Aaronson, Neil, Ardern-Jones, Audrey, Bangma, Chris, Dearnaley, David, Eyfjord, Jorunn, Rothwell, Jeanette, Falconer, Alison, Gronberg, Henrik, Johannsson, Oskar, Kote-Jarai, Zsofia, Axcrona, Ulrika, Melia, Jane, McKinley, Joanne, Mitra, Anita V, Moynihan, Clare, Rennert, Gad, Suri, Mohnish, Wilson, Penny, Killick, Emma, Moss, Sue

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OpenSAFELY: A platform for analysing electronic health records designed for reproducible research by Nab, Linda, Schaffer, Andrea L., Hulme, William, DeVito, Nicholas J., Dillingham, Iain, Wiedemann, Milan, Andrews, Colm D., Curtis, Helen, Fisher, Louis, Green, Amelia, Massey, Jon, Walters, Caroline E., Higgins, Rose, Cunningham, Christine, Morley, Jessica, Mehrkar, Amir, Hart, Liam, Davy, Simon, Evans, David, Hickman, George, Inglesby, Peter, Morton, Caroline E., Smith, Rebecca M., Ward, Tom, O'Dwyer, Thomas, Maude, Steven, Bridges, Lucy, Butler‐Cole, Ben F. C., Stables, Catherine L., Stokes, Pete, Bates, Chris, Cockburn, Jonny, Hester, Frank, Parry, John, Bhaskaran, Krishnan, Schultze, Anna, Rentsch, Christopher T., Mathur, Rohini, Tomlinson, Laurie A., Williamson, Elizabeth J., Smeeth, Liam, Walker, Alex, Bacon, Sebastian, MacKenna, Brian, Goldacre, Ben

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Effect of Nitric Oxide via Cardiopulmonary Bypass on Ventilator-Free Days in Young Children Undergoing Congenital Heart Disease Surgery: The NITRIC Randomized Clinical Trial by Schlapbach, Luregn J, Gibbons, Kristen S, Horton, Stephen B, Johnson, Kerry, Long, Debbie A, Buckley, David H. F, Erickson, Simon, Festa, Marino, d’Udekem, Yves, Alphonso, Nelson, Winlaw, David S, Delzoppo, Carmel, van Loon, Kim, Jones, Mark, Young, Paul J, Butt, Warwick, Schibler, Andreas

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Comparison of Modeling Methods to Determine Liver-to-blood Inocula and Parasite Multiplication Rates During Controlled Human Malaria Infection by Douglas, Alexander D., Edwards, Nick J., Duncan, Christopher J. A., Thompson, Fiona M., Sheehy, Susanne H., O'Hara, Geraldine A., Anagnostou, Nicholas, Walther, Michael, Webster, Daniel P., Dunachie, Susanna J., Porter, David W., Andrews, Laura, Gilbert, Sarah C., Draper, Simon J., Hill, Adrian V. S., Bejon, Philip

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Compaction study of food powders using metamaterial split ring resonator based sensor by Aswathi, P. V., Sebastian, Anju, Simon, Sikha K., Bindu, C., Joseph, V. P., Andrews, Jolly

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Clinical and Viral Factors Associated With Disease Severity and Subsequent Wheezing in Infants With Respiratory Syncytial Virus Infection by McGinley, Joseph P, Lin, Gu Lung, Öner, Deniz, Golubchik, Tanya, O’Connor, Daniel, Snape, Matthew D, Gruselle, Olivier, Langedijk, Annefleur C, Wildenbeest, Joanne, Openshaw, Peter, Nair, Harish, Aerssens, Jeroen, Bont, Louis, Martinón-Torres, Federico, Drysdale, Simon B, Pollard, Andrew J

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De Novo and Inherited Loss-of-Function Variants in TLK2: Clinical and Genotype-Phenotype Evaluation of a Distinct Neurodevelopmental Disorder by Reijnders, Margot R.F., Miller, Kerry A., Alvi, Mohsan, Goos, Jacqueline A.C., Lees, Melissa M., de Burca, Anna, Henderson, Alex, Kraus, Alison, Mikat, Barbara, de Vries, Bert B.A., Isidor, Bertrand, Kerr, Bronwyn, Marcelis, Carlo, Schluth-Bolard, Caroline, Deshpande, Charu, Ruivenkamp, Claudia A.L., Wieczorek, Dagmar, Baralle, Diana, Blair, Edward M., Engels, Hartmut, Lüdecke, Hermann-Josef, Eason, Jacqueline, Santen, Gijs W.E., Clayton-Smith, Jill, Chandler, Kate, Tatton-Brown, Katrina, Payne, Katelyn, Helbig, Katherine, Radtke, Kelly, Nugent, Kimberly M., Cremer, Kirsten, Strom, Tim M., Bird, Lynne M., Sinnema, Margje, Bitner-Glindzicz, Maria, van Dooren, Marieke F., Alders, Marielle, Koopmans, Marije, Brick, Lauren, Kozenko, Mariya, Harline, Megan L., Klaassens, Merel, Steinraths, Michelle, Cooper, Nicola S., Edery, Patrick, Yap, Patrick, Terhal, Paulien A., van der Spek, Peter J., Lakeman, Phillis, Taylor, Rachel L., Littlejohn, Rebecca O., Pfundt, Rolph, Mercimek-Andrews, Saadet, Stegmann, Alexander P.A., Kant, Sarina G., McLean, Scott, Joss, Shelagh, Swagemakers, Sigrid M.A., Douzgou, Sofia, Wall, Steven A., Küry, Sébastien, Calpena, Eduardo, Koelling, Nils, McGowan, Simon J., Twigg, Stephen R.F., Mathijssen, Irene M.J., Nellaker, Christoffer, Brunner, Han G., Wilkie, Andrew O.M.

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Interlaboratory comparison of a multiplex immunoassay that measures human serum IgG antibodies against six-group B streptococcus polysaccharides by Le Doare, Kirsty, Gaylord, Michelle A., Anderson, Annaliesa S., Andrews, Nick, Baker, Carol J., Bolcen, Shanna, Felek, Arif, Giardina, Peter C., Grube, Christopher D., Hall, Tom, Hallis, Bassam, Izu, Alane, Madhi, Shabir A., Maniatis, Pete, Matheson, Mary, Mawas, Fatme, McKeen, Andrew, Rhodes, Julia, Alston, Bailey, Patel, Palak, Schrag, Stephanie, Simon, Raphael, Tan, Charles Y., Taylor, Stephen, Kwatra, Gaurav, Gorringe, Andrew

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