Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway by Li, Gang, Diogo, Dorothée, Wu, Di, Spoonamore, Jim, Dancik, Vlado, Franke, Lude, Kurreeman, Fina, Rossin, Elizabeth J, Duclos, Grant, Hartland, Cathy, Zhou, Xuezhong, Li, Kejie, Liu, Jun, De Jager, Philip L, Siminovitch, Katherine A, Zhernakova, Alexandra, Raychaudhuri, Soumya, Bowes, John, Eyre, Steve, Padyukov, Leonid, Gregersen, Peter K, Worthington, Jane, Gupta, Namrata, Clemons, Paul A, Stahl, Eli, Tolliday, Nicola, Plenge, Robert M

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Application of user-guided automated cytometric data analysis to large-scale immunoprofiling of invariant natural killer T cells by Hu, Xinli, Kim, Hyun, Brennan, Patrick J., Han, Buhm, Baecher-Allan, Clare M., De Jager, Philip L., Brenner, Michael B., Raychaudhuri, Soumya

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1012 Deep peripheral blood immunophenotyping identifies a subgroup of lupus nephritis patients characterized by high type 1 interferon signaling, persistent activated immune cells... by Horisberger, Alice, Griffith, Alec, Arazi, Arnon, Keegan, Joshua, Howard, Kaitlyn, Sasaki, Takanori, Ghosh, Tusharkanti, Fava, Andrea, Beuschel, Rebecca, Inamo, Jun, Pulford, John, Murzin, Ekaterina, Hancock, Brandon, Preisinger, Katie, Gutierrez-Arcelus, Maria, Eisenhaure, Thomas M, Guthridge, Joel, Hoover, Paul J, Dall’Era, Maria, Wofsy, David, Kamen, Diane L, Kalunian, Kenneth C, Furie, Richard, Belmont, Michael, Izmirly, Peter, Clancy, Robert, Hildeman, David, Woodle, Steve, Apruzzese, William, McMahon, Maureen A, Grossman, Jennifer, Barnas, Jennifer L, Payan-Schober, Fernanda, Ishimori, Mariko, Weisman, Michael, Kretzler, Matthias, Berthier, Celine C, Hodgin, Jeffrey, Putterman, Chaim, Hacohen, Nir, Brenner, Michael B, Anolik, Jennifer H, Davidson, Anne, James, Judith A, Raychaudhuri, Soumya, Petri, Michelle A, Buyon, Jill P, Diamond, Betty, Zhang, Fan, Lederer, James A, Rao, Deepak A

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1002 Single cell transcriptomics in kidney tissue from African American patients enrolled in the accelerating medicines partnership (AMP) implicates tubular cells in the pathogenes... by Carlucci, Philip M, Shwetar, Jasmine, Gurajala, Siddarth, Xiao, Qian, Mears, Joseph, Preisinger, Katie, Zaminski, Devyn, Deonaraine, Kristina, Izmirly, Peter, Fava, Andrea, James, Judith A, Guthridge, Joel, Rovin, Brad, Madhavan, Sethu, DeJager, Wade, Wofsy, David, Wu, Ming, Putterman, Chaim, Rao, Deepak, Diamond, Betty, Fine, Derek, Monroy-Trujillo, Jose, Haag, Kristin, Michael Belmont, H, Apruzzese, William, Davidson, Anne, Payan-Schober, Fernanda, Furie, Richard, Hoover, Paul, Berthier, Celine C, Dall’Era, Maria, Cho, Kerry, Kamen, Diane, Kalunian, Kenneth, Anolik, Jennifer, Arazi, Arnon, Raychaudhuri, Soumya, Hacohen, Nir, Petri, Michelle, Clancy, Robert, Ruggles, Kelly, Buyon, Jill

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1009 In-depth analysis of myeloid cell subsets in lupus nephritis kidneys provides insights into disease mechanisms: lessons from the accelerating medicines partnership (AMP) in RA... by Arazi, Arnon, Hoover, Paul J, Eisenhaure, Thomas M, Gurajala, Siddarth, Xiao, Qian, Mears, Joseph, Rao, Deepak A, Berthier, Celine C, Fava, Andrea, Peters, Michael, Jones, Tony, Sakaue, Saori, Apruzzese, William, Barnas, Jennifer L, Fine, Derek, Lederer, James, Furie, Richard, Hildeman, David A, Woodle, Steve, James, Judith A, Guthridge, Joel M, Dall’Era, Maria, Wofsy, David, Izmirly, Peter M, Michael Belmont, H, Clancy, Robert, Kamen, Diane L, Putterman, Chaim, Tuschl, Thomas, McMahon, Maureen A, Grossman, Jennifer, Kalunian, Kenneth C, Payan-Schober, Fernanda, Ishimori, Mariko, Weisman, Michael, Kretzler, Matthias, Hodgin, Jeffery, Brenner, Michael B, Anolik, Jennifer H, Petri, Michelle A, Buyon, Jill P, Raychaudhuri, Soumya, Diamond, Betty, Hacohen, Nir, Davidson, Anne

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Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene by Okada, Yukinori, Diogo, Dorothee, Greenberg, Jeffrey D, Mouassess, Faten, Achkar, Walid A L, Fulton, Robert S, Denny, Joshua C, Gupta, Namrata, Mirel, Daniel, Gabriel, Stacy, Li, Gang, Kremer, Joel M, Pappas, Dimitrios A, Carroll, Robert J, Eyler, Anne E, Trynka, Gosia, Stahl, Eli A, Cui, Jing, Saxena, Richa, Coenen, Marieke J H, Guchelaar, Henk-Jan, Huizinga, Tom W J, Dieudé, Philippe, Mariette, Xavier, Barton, Anne, Canhão, Helena, Fonseca, João E, de Vries, Niek, Tak, Paul P, Moreland, Larry W, Bridges, Jr, S Louis, Miceli-Richard, Corinne, Choi, Hyon K, Kamatani, Yoichiro, Galan, Pilar, Lathrop, Mark, Raj, Towfique, De Jager, Philip L, Raychaudhuri, Soumya, Worthington, Jane, Padyukov, Leonid, Klareskog, Lars, Siminovitch, Katherine A, Gregersen, Peter K, Mardis, Elaine R, Arayssi, Thurayya, Kazkaz, Layla A, Plenge, Robert M

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Rheumatoid Arthritis Synovial Inflammation Quantification Using Computer Vision by Guan, Steven, Mehta, Bella, Slater, David, Thompson, James R., DiCarlo, Edward, Pannellini, Tania, Pearce‐Fisher, Diyu, Zhang, Fan, Raychaudhuri, Soumya, Hale, Caryn, Jiang, Caroline S., Goodman, Susan, Orange, Dana E.

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Quantifying how TCR sequence variation affects T cell fate at single-cell resolution by Lagattuta, Kaitlyn, Kwun, Mujin, Raychaudhuri, Soumya

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Identification of Osteopontin as a Prognostic Plasma Marker for Head and Neck Squamous Cell Carcinomas by LE, Quynh-Thu, SUTPHIN, Patrick D, RAYCHAUDHURI, Soumya, YU, Sheue Ching T, TERRIS, David J, HO SHENG LIN, LUM, Bert, PINTO, Harlan A, KOONG, Albert C, GIACCIA, Amato J

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Human leukocyte antigen-DQA104:01 and rs2040406 variants are associated with elevated risk of childhood Burkitt lymphoma by Liu, Zhiwei, Luo, Yang, Kirimunda, Samuel, Verboom, Murielle, Onabajo, Olusegun O., Gouveia, Mateus H., Ogwang, Martin D., Kerchan, Patrick, Reynolds, Steven J., Tenge, Constance N., Were, Pamela A., Kuremu, Robert T., Wekesa, Walter N., Masalu, Nestory, Kawira, Esther, Kinyera, Tobias, Otim, Isaac, Legason, Ismail D., Nabalende, Hadijah, Dhudha, Herry, Ayers, Leona W., Bhatia, Kishor, Goedert, James J., Cole, Nathan, Luo, Wen, Liu, Jia, Manning, Michelle, Hicks, Belynda, Prokunina-Olsson, Ludmila, Chagaluka, George, Johnston, W. Thomas, Mutalima, Nora, Borgstein, Eric, Liomba, George N., Kamiza, Steve, Mkandawire, Nyengo, Mitambo, Collins, Molyneux, Elizabeth M., Newton, Robert, Hsing, Ann W., Mensah, James E., Adjei, Anthony A., Hutchinson, Amy, Carrington, Mary, Yeager, Meredith, Blasczyk, Rainer, Chanock, Stephen J., Raychaudhuri, Soumya, Mbulaiteye, Sam M.

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Using chromatin marks to interpret and localize genetic associations to complex human traits and diseases by Trynka, Gosia, Raychaudhuri, Soumya

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1112 Change in urinary biomarkers at three months predicts 1-year treatment response of lupus nephritisbetter than proteinuria by Fava, Andrea, Magder, Laurence, Goldman, Daniel W, Buyon, Jill, Diamond, Betty, Guthdridge, Joel, James, Judith A, Apruzzese, William, Fine, Derek, Trujillo, Jose Monroy, Atta, Mohamed G, Izmirly, Peter, Michael Belmont, H, Davidson, Anne, Dall’Era, Maria, Rao, Deepak, Arazi, Arnon, Hacohen, Nir, Raychaudhuri, Soumya

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LO-006 Change in urinary biomarkers at three months predicts 1-year treatment response of lupus nephritis better than proteinuria by Fava, Andrea, Buyon, Jill, Magder, Laurence, Hodgin, Jeffrey, Rosenberg, Avi, Demeke, Dawit, Rao, Deepak, Arazi, Arnon, Alessandra Ida Celia, Putterman, Chaim, Anolik, Jennifer, Barnas, Jennifer, Maria Dall’Era, Wofsy, David, Furie, Richard, Kamen, Diane, Kalunian, Kenneth, James, Judith A, Guthridge, Joel, Atta, Mohamed G, Monroy-Trujillo, Jose, Fine, Derek, Clancy, Robert, Belmont, H Michael, Izmirly, Peter, Apruzzese, William, Goldman, Daniel, Berthier, Celine, Hoover, Paul, Hacohen, Nir, Raychaudhuri, Soumya, Davidson, Anne, Diamond, Betty, Petri, Michelle

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1107 Immune cell heterogeneity in lupus nephritis kidneys and its relation to histopathological features: lessons from the accelerating medicines partnership (AMP) in SLE Consortiu... by Arazi, Arnon, Mears, Jospeh, Eisenhaure, Thomas M, Xiao, Qian, Hoover, Paul J, Rao, Deepak A, Berthier, Celine C, Fava, Andrea, Gurajala, Siddarth, Peters, Michael, Jones, Tony, Sakaue, Saori, Apruzzese, William, Barnas, Jennifer L, Fine, Derek, Lederer, James, Furie, Richard, Davidson, Anne, Hildeman, David A, Woodle, Steve, James, Judith A, Guthridge, Joel M, Dall’Era, Maria, Wofsy, David, Izmirly, Peter M, Michael Belmont, H, Clancy, Robert, Kamen, Diane L, Putterman, Chaim, Tuschl, Thomas, McMahon, Maureen A, Grossman, Jennifer, Kalunian, Kenneth C, Payan-Schober, Fernanda, Ishimori, Mariko, Weisman, Michael, Kretzler, Matthias, Hodgin, Jeffery, Brenner, Michael B, Anolik, Jennifer H, Petri, Michelle A, Buyon, Jill P, Raychaudhuri, Soumya, Hacohen, Nir, Diamond, Betty

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HATK: HLA analysis toolkit by Choi, Wanson, Luo, Yang, Raychaudhuri, Soumya, Han, Buhm

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Methods and Insights from Single-Cell Expression Quantitative Trait Loci by Kang, Joyce B, Raveane, Alessandro, Nathan, Aparna, Soranzo, Nicole, Raychaudhuri, Soumya

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Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis by Rao, Deepak A., Gurish, Michael F., Marshall, Jennifer L., Slowikowski, Kamil, Fonseka, Chamith Y., Liu, Yanyan, Donlin, Laura T., Henderson, Lauren A., Wei, Kevin, Mizoguchi, Fumitaka, Teslovich, Nikola C., Weinblatt, Michael E., Massarotti, Elena M., Coblyn, Jonathan S., Helfgott, Simon M., Lee, Yvonne C., Todd, Derrick J., Bykerk, Vivian P., Goodman, Susan M., Pernis, Alessandra B., Ivashkiv, Lionel B., Karlson, Elizabeth W., Nigrovic, Peter A., Filer, Andrew, Buckley, Christopher D., Lederer, James A., Raychaudhuri, Soumya, Brenner, Michael B.

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Single-cell eQTL models reveal dynamic T cell state dependence of disease loci by Nathan, Aparna, Asgari, Samira, Ishigaki, Kazuyoshi, Valencia, Cristian, Amariuta, Tiffany, Luo, Yang, Beynor, Jessica I., Baglaenko, Yuriy, Suliman, Sara, Price, Alkes L., Lecca, Leonid, Murray, Megan B., Moody, D. Branch, Raychaudhuri, Soumya

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Single-cell genomics meets human genetics by Cuomo, Anna S. E., Nathan, Aparna, Raychaudhuri, Soumya, MacArthur, Daniel G., Powell, Joseph E.

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Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations by Luo, Yang, Li, Xinyi, Wang, Xin, Gazal, Steven, Mercader, Josep Maria, Neale, Benjamin M, Florez, Jose C, Auton, Adam, Price, Alkes L, Finucane, Hilary K, Raychaudhuri, Soumya

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