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    Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial by Del Prato, Stefano, Pavo, Imre, Weerakkody, Govinda J, Yang, Zhengyu, Aizenberg, Diego, Wynne, Alan G, Wiese, Russell J, Arora, Samir, Calderon, Rafael B, Butuk, David J, Chaychi, Leila, Curtis, Brian M, Chochinov, Ronald, Chow, Christopher, Cone, Clancy L, Dungan, Kathleen, Gaudiani, Linda, Herandez-Vazquez, Luis, Hsia, Stanley H, Kutner, Mark E, Loy, Juan, Miranda, Francisco G, Oliver, Michael J, Parke, Michael T, Philis-Tsimikas, Athena, Rosenstock, Julio, Sorial, Ehab, Stonesifer, Larry D, Stringam, Stanley, Van, Joanna T, Vazquez-Tanus, Jose B, Reyes, Ramon, Karimjee, Najmuddin, Martin, Earl E, Fraser, Neil J, Bhargava, Anuj, Wynne, Alan G, Billings, Liana, Walsh, Patrick, Shubrook, Jay, Knouse, Albert B, Mayfield, Ronald K, Bitar, Fahed G, de la Cuesta, Carmen, Morales Portillo, Cristobal J, Quesada Charneco, Miguel, Tofe Povedano, Santiago, Vazquez, Luis, Soto Gonzalez, Alfonso, Ciomos, Daniela, Neacsu, Valentina, Stern, Naftali, Sofer, Yael, Sack, Jessica, Tirosh, Amir, Shehadeh, Naim, Darawsha, Mahmud, Skripova, Dasa, Pavleova, Eva, Kubincova, Ludmila, Merciakova, Martina, St-Amour, Eric, Yared, Zeina, Blouin, Francois, Aggarwal, Naresh K, Bajaj, Harpreet, Tailor, Chetna, Egan, Alan, St.Onge, Natasha, Borges, Joao L C, Franco, Denise R, Souza, Filipe D, Russo, Luis Augusto T, Sassone, Sonia A, Steinacher, Andrea, Perez Manghi, Federico C, Orio, Silvia I, Gelersztein, Elizabeth, Fretes, José O, Calella, Pedro R F, Zaidman, Cesar J, Chertkoff, Alejandro, Gonzalez Galvez, Guillermo, Calvo, Cesar G, Sowinski, Dariusz, Jozefowska, Malgorzata, Skokowska, Ewa, Modzelewska, Anna, Gilfillan, Christopher, Morbey, Claire, Kaur, Kamal, Kemp, Laurence, Shea, Antony J, Kunitsyna, Marina A, Ou, Horng-Yih, Chen, Jung-Fu, Hwu, Chii-Min, Doupis, John, Pagkalos, Emmanouil, Mouslech, Zadalla

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    Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial by Garvey, W Timothy, Frias, Juan P, Jastreboff, Ania M, le Roux, Carel W, Sattar, Naveed, Aizenberg, Diego, Mao, Huzhang, Zhang, Shuyu, Ahmad, Nadia N, Bunck, Mathijs C, Benabbad, Imane, Zhang, Xiaotian M, Abalos, Franklin H., Manghi, Federico C.P., Zaidman, Cesar J., Vico, Marisa L., Aizenberg, Diego, Costanzo, Pablo R., Serra, Leonardo P., MacKinnon, Ignacio J., Hissa, Miguel N., Vidotti, Maria H., Kerr Saraiva, Jose F., Alves, Breno B., Franco, Denise R., Moratto, Otavio, Murthy, Sreenivasa, Goyal, Ghanshyam, Yamasaki, Yoshimitsu, Sato, Nobuyuki, Inoue, Satoshi, Asakura, Taro, Shestakova, Marina, Khaykina, Elena, Troshina, Ekaterina, Vorokhobina, Natalia, Ametov, Alexander, Tu, Shih-Te, Yang, Chwen-Yi, Lee, I-Te, Huang, Chien-Ning, Ou, Horng-Yih, Freeman, George, Machineni, Sriram, Klein, Klara, Sultan, Senan, Parsa, Alan, Otero-Martinez, Juan, Gonzalez, Alex, Bhargava, Anuj, Brian, Susan, Ince, Carlos, Plantholt, Stephen, Cole, Jeremy, Lacour, Audrey, Vega, Damaris, de Souza, Jose, Rohlf, Jane L., St. John, Roy C., Horowitz, Barry, Audish, Hanid, Galindo, Rodolfo, Umpiperrez, Guillermo, Ard, Jamy, Curtis, Brian, Garvey, William T., Fraser, Neil J., Mandry, Jose, Mohseni, Rizwana, Mayfield, Ronald, Powell, Talessa, Vance, Carl, Ong, Stephen, Lewy-Alterbaum, Ana L., Murray, Alexander, Al-Karadsheh, Amer, Yacoub, Tamer, Roberts, Kevin, Fried, David L., Rosenstock, Julio, Pulla, Bharathi, Bode, Bruce, Frias, Juan, Klaff, Leslie, Brazg, Ronald, Van, Joanna, Tan, Anjanette, Briskin, Toby, Rhee, Margaret, Chaicha-Brom, Tira, Hartley, Paul A., Nunez, Lazaro, Cortes-Maisonet, Gregorio, Soucie, Gary, Hsia, Stanley, Jones, Thomas

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    De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias by Helbig, Katherine L., Lauerer, Robert J., Bahr, Jacqueline C., Souza, Ivana A., Uysal, Betül, Gandini, Maria A., Huang, Sun, Keren, Boris, Mignot, Cyril, Billette de Villemeur, Thierry, Nava, Caroline, Valence, Stéphanie, Buratti, Julien, Fagerberg, Christina R., Soerensen, Kristina P., Kamsteeg, Erik-Jan, Koolen, David A., Gunning, Boudewijn, Schelhaas, H. Jurgen, Fox, Jordana, Bakhtiari, Somayeh, Jarrar, Randa, Lindstrom, Kristin, Jin, Sheng Chih, Zeng, Xue, Bilguvar, Kaya, Papavasileiou, Antigone, Xing, Qinghe, Zhu, Changlian, Boysen, Katja, Vairo, Filippo, Klee, Eric W., Tillema, Jan-Mendelt, Payne, Eric T., Cousin, Margot A., Kruisselbrink, Teresa M., Wick, Myra J., Baker, Joshua, Smith, Nicholas, Angrist, Misha, Ashley, Patricia, Bidegain, Margarita, Chambers, Eileen, Cope, Heidi, Cotten, C. Michael, Curington, Theresa, Davis, Erica E., Fisher, Kimberley, French, Amanda, Gallentine, William, Hill, Kevin, Kansagra, Sujay, Katsanis, Sara, Kurtzberg, Joanne, Marcus, Jeffrey, McDonald, Marie, Mikati, Mohammed, Miller, Stephen, Murtha, Amy, Perilla, Yezmin, Pizoli, Carolyn, Ross, Sherry, Sadeghpour, Azita, Smith, Edward, Wiener, John, Corbett, Mark A., Goldmann, Eva, Kichula, Elizabeth, Segal, Eric, Jackson, Kelly E., Asamoah, Alexander, McCarrier, Julie, Botto, Lorenzo D., Tvrdik, Tatiana, Cascino, Gregory D., Klingerman, Sherry, Neumann, Catherine, Nolan, Melinda A., Snell, Russell G., Lehnert, Klaus, Sadleir, Lynette G., Kvarnung, Malin, Guerrini, Renzo, Friez, Michael J., Lyons, Michael J., Leonhard, Jennifer, Kringlen, Gabriel, El Achkar, Christelle M., Smith, Lacey A., Carss, Keren J., Rankin, Julia, Zeman, Adam, Blyth, Moira, Kerr, Bronwyn, Ruiz, Karla, Urquhart, Jill, Banka, Siddharth, Scheffer, Ingrid E., Zamponi, Gerald W., Mefford, Heather C.

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