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Search Results - Steffey, Melinda
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Design and Synthesis of Potent HIV-1 Protease Inhibitors Incorporating Hexahydrofuropyranol-Derived High Affinity P2 Ligands: Structure−Activity Studies and Biological Evaluation
by
Ghosh, Arun K
,
Chapsal, Bruno D
,
Baldridge, Abigail
,
Steffey, Melinda P
,
Walters, D. Eric
,
Koh, Yasuhiro
,
Amano, Masayuki
,
Mitsuya, Hiroaki
Published in
Journal of medicinal chemistry
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Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1′-P2′ ligands
by
Ghosh, Arun K.
,
Sean Fyvie, W.
,
Brindisi, Margherita
,
Steffey, Melinda
,
Agniswamy, Johnson
,
Wang, Yuan-Fang
,
Aoki, Manabu
,
Amano, Masayuki
,
Weber, Irene T.
,
Mitsuya, Hiroaki
Published in
Bioorganic & medicinal chemistry letters
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P2′ Benzene Carboxylic Acid Moiety Is Associated with Decrease in Cellular Uptake: Evaluation of Novel Nonpeptidic HIV-1 Protease Inhibitors Containing P2 bis-Tetrahydrofuran Moiet...
by
YEDIDI, Ravikiran S
,
MAEDA, Kenji
,
DAS, Debananda
,
WINGFIELD, Paul T
,
GHOSH, Arun K
,
MITSUYA, Hiroaki
,
SEAN FYVIE, W
,
STEFFEY, Melinda
,
DAVIS, David A
,
PALMER, Ira
,
AOKI, Manabu
,
KAUFMAN, Joshua D
,
STAHL, Stephen J
,
GARIMELLA, Harisha
Published in
Antimicrobial Agents and Chemotherapy
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Design, synthesis, biological evaluation and X-ray structural studies of HIV-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as P2-ligands
by
Ghosh, Arun K
,
Martyr, Cuthbert D
,
Kassekert, Luke A
,
Nyalapatla, Prasanth R
,
Steffey, Melinda
,
Agniswamy, Johnson
,
Wang, Yuan-Fang
,
Weber, Irene T
,
Amano, Masayuki
,
Mitsuya, Hiroaki
Published in
Organic & biomolecular chemistry
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Substituent effects on P2-cyclopentyltetrahydrofuranyl urethanes: Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors
by
Ghosh, Arun K.
,
Chapsal, Bruno D.
,
Steffey, Melinda
,
Agniswamy, Johnson
,
Wang, Yuan-Fang
,
Amano, Masayuki
,
Weber, Irene T.
,
Mitsuya, Hiroaki
Published in
Bioorganic & medicinal chemistry letters
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Design, Synthesis, and X-ray Structure of Substituted Bis-tetrahydrofuran (Bis-THF)-Derived Potent HIV-1 Protease Inhibitors
by
Ghosh, Arun K
,
Martyr, Cuthbert D
,
Steffey, Melinda
,
Wang, Yuan-Fang
,
Agniswamy, Johnson
,
Amano, Masayuki
,
Weber, Irene T
,
Mitsuya, Hiroaki
Published in
ACS medicinal chemistry letters
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Design, Synthesis, Biological Evaluation, and X‐ray Studies of HIV‐1 Protease Inhibitors with Modified P2′ Ligands of Darunavir
by
Ghosh, Arun K.
,
Fyvie, W. Sean
,
Brindisi, Margherita
,
Steffey, Melinda
,
Agniswamy, Johnson
,
Wang, Yuan‐Fang
,
Aoki, Manabu
,
Amano, Masayuki
,
Weber, Irene T.
,
Mitsuya, Hiroaki
Published in
ChemMedChem
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Design of HIV-1 Protease Inhibitors with C3-Substituted Hexahydrocyclopentafuranyl Urethanes as P2-Ligands: Synthesis, Biological Evaluation, and Protein–Ligand X-ray Crystal Struc...
by
Ghosh, Arun K
,
Chapsal, Bruno D
,
Parham, Garth L
,
Steffey, Melinda
,
Agniswamy, Johnson
,
Wang, Yuan-Fang
,
Amano, Masayuki
,
Weber, Irene T
,
Mitsuya, Hiroaki
Published in
Journal of medicinal chemistry
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Design, synthesis, biological evaluation and X-ray structural studies of HIV-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as P2-ligandsElect...
by
Ghosh, Arun K
,
Martyr, Cuthbert D
,
Kassekert, Luke A
,
Nyalapatla, Prasanth R
,
Steffey, Melinda
,
Agniswamy, Johnson
,
Wang, Yuan-Fang
,
Weber, Irene T
,
Amano, Masayuki
,
Mitsuya, Hiroaki
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Design and Synthesis of Potent HIV-1 Protease Inhibitors Incorporating Hexahydrofuropyranol-Derived High Affinity P 2 Ligands: Structure−Activity Studies and Biological Evaluation...
by
Ghosh, Arun K.
,
Chapsal, Bruno D.
,
Baldridge, Abigail
,
Steffey, Melinda P.
,
Walters, D. Eric
,
Koh, Yasuhiro
,
Amano, Masayuki
,
Mitsuya, Hiroaki
Published in
Journal of medicinal chemistry
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Design of substituted bis-Tetrahydrofuran (bis-THF)-derived Potent HIV-1 Protease Inhibitors, Protein-ligand X-ray Structure, and Convenient Syntheses of bis-THF and Substituted bi...
by
Ghosh, Arun K
,
Martyr, Cuthbert D
,
Steffey, Melinda
,
Wang, Yuan-Fang
,
Agniswamy, Johnson
,
Amano, Masayuki
,
Weber, Irene T
,
Mitsuya, Hiroaki
Published in
ACS medicinal chemistry letters
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Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P(2) ligands: structure-activity studies and biological evaluation
by
Ghosh, Arun K
,
Chapsal, Bruno D
,
Baldridge, Abigail
,
Steffey, Melinda P
,
Walters, D Eric
,
Koh, Yasuhiro
,
Amano, Masayuki
,
Mitsuya, Hiroaki
Published in
Journal of medicinal chemistry
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