Comments on Letter to the Editor entitled: “Role of electrophysiological evaluation for the best device choice to prevent sudden cardiac death in patients with Myotonic Dystrophy T... by Sommerville, R.B, Vincenti, M.G, Winborn, K, Casey, A, Stitziel, N.O, Connolly, A.M, Mann, D.L

Get full text

Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials by Mega, Jessica L, Dr, Stitziel, Nathan O, Dr, Smith, J Gustav, MD, Chasman, Daniel I, PhD, Caulfield, Mark J, Prof, Devlin, James J, PhD, Nordio, Francesco, PhD, Hyde, Craig L, PhD, Cannon, Christopher P, Prof, Sacks, Frank M, Prof, Poulter, Neil R, Prof, Sever, Peter S, Prof, Ridker, Paul M, Prof, Braunwald, Eugene, Prof, Melander, Olle, Prof, Kathiresan, Sekar, MD, Sabatine, Marc S, Prof

Get full text

topoSNP: a topographic database of non‐synonymous single nucleotide polymorphisms with and without known disease association by Stitziel, Nathan O., Binkowski, T. Andrew, Tseng, Yan Yuan, Kasif, Simon, Liang, Jie

Get full text

Structural Location of Disease-associated Single-nucleotide Polymorphisms by Stitziel, Nathan O., Tseng, Yan Yuan, Pervouchine, Dimitri, Goddeau, David, Kasif, Simon, Liang, Jie

Get full text

Improving the prediction of major adverse cardiovascular events in patients with hypertrophic cardiomyopathy by adding plasma SVEP1 to conventional clinical model including NT-proB... by Osawa, I, Akita, K, Hasegawa, K, Fifer, M A, Tower-Rader, A, Reilly, M P, Maurer, M S, Stitziel, N O, Javaheri, A, Shimada, Y J

Get full text

Prognostic value of diastolic filling parameters derived using a novel image processing technique in patients ≥70 years of age with congestive heart failure by Rich, Michael W., Stitziel, Nathan O., Kovács, Sándor J.

Get full text

Genetic Risk, Coronary Heart Disease Events, and the Clinical Benefit of Statin Therapy by Mega, JL, Stitziel, NO, Smith, JG, Chasman, DI, Caulfield, M, Devlin, JJ, Nordio, F, Hyde, C, Cannon, CP, Sacks, F, Poulter, N, Sever, P, Ridker, PM, Braunwald, E, Melander, O, Kathiresan, S, Sabatine, MS

Get full text

Membrane-associated and secreted genes in breast cancer by STITZIEL, Nathan O, MAR, Brenton G, JIE LIANG, WESTBROOK, Carol A

Get full text

ANGPTL3 deficiency impairs lipoprotein production and produces adaptive changes in hepatic lipid metabolism by Burks, Kendall H., Xie, Yan, Gildea, Michael, Jung, In-Hyuk, Mukherjee, Sandip, Lee, Paul, Pudupakkam, Upasana, Wagoner, Ryan, Patel, Ved, Santana, Katherine, Alisio, Arturo, Goldberg, Ira J., Finck, Brian N., Fisher, Edward A., Davidson, Nicholas O., Stitziel, Nathan O.

Get full text

Diagnosis and management of adult hereditary cardio-neuromuscular disorders: A model for the multidisciplinary care of complex genetic disorders by Sommerville, R. Brian, MD, Vincenti, Margherita Guzzi, BS, Winborn, Kathleen, RN, BSN, Casey, Anne, RN, BSN, Stitziel, Nathan O., M.D., Ph.D, Connolly, Anne M., M.D, Mann, Douglas L., M.D

Get full text

Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease by Khera, Amit V, Won, Hong-Hee, Peloso, Gina M, O’Dushlaine, Colm, Liu, Dajiang, Stitziel, Nathan O, Natarajan, Pradeep, Nomura, Akihiro, Emdin, Connor A, Gupta, Namrata, Borecki, Ingrid B, Asselta, Rosanna, Duga, Stefano, Merlini, Piera Angelica, Correa, Adolfo, Kessler, Thorsten, Wilson, James G, Bown, Matthew J, Hall, Alistair S, Braund, Peter S, Carey, David J, Murray, Michael F, Kirchner, H. Lester, Leader, Joseph B, Lavage, Daniel R, Manus, J. Neil, Hartzel, Dustin N, Samani, Nilesh J, Schunkert, Heribert, Marrugat, Jaume, Elosua, Roberto, McPherson, Ruth, Farrall, Martin, Watkins, Hugh, Lander, Eric S, Rader, Daniel J, Danesh, John, Ardissino, Diego, Gabriel, Stacey, Willer, Cristen, Abecasis, Gonçalo R, Saleheen, Danish, Dewey, Frederick E, Kathiresan, Sekar

Get full text

Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol by Lange, Leslie A., Schmidt, Ellen M., Bizon, Chris, Jun, Goo, Auer, Paul, Li, Kuo-ping, Locke, Adam, Rivas, Manuel A., Feitosa, Mary F., Zhang, Qunyuan, Huffman, Jennifer E., Crosby, Jacy, Robinson, Jennifer G., Crosslin, David R., Rosenthal, Elisabeth A., Tsai, Michael, Rieder, Mark J., Fox, Ervin R., van Duijn, Cornelia M., Taylor, Herman A., Loos, Ruth J.F., Ballantyne, Christie M., Reiner, Alexander P., Cupples, L. Adrienne, Kang, Hyun Min, Lettre, Guillaume, Rader, Daniel J., Reilly, Muredach P., Stoletzki, Nina, Barr, R. Graham, Benjamin, Emelia J., Carr, Jeff, Dupuis, Josée, Ellis, Jaclyn, Fornage, Myriam, Goff, David, Grody, Wayne, Heard-Costa, Nancy L., Levy, Daniel, Li, Dalin, Loria, Cay, Mackey, Rachel, Quinlan, Aaron R., Rice, Kenneth, Sanders, Jill P., Tracy, Russell P., Tsai, Michael Y., Wassel, Chrstina L., Watson, Karol, Wilson, Gregory, Wilson, James G., Zakai, Neil A., Nalls, Michael, Bamshad, Michael J., Accurso, Frank, Beaty, Terri, Caplan, Daniel, Chidekel, Aaron, Christiani, David C., De Paula, Alicia, Gutierrez, Hector, Hassoun, Paul M., Hiatt, Peter, Hummer, Laura K., Kim, Yoonhee, Lin, Xihong, Louie, Tin L., Mathias, Rasika A., McNamara, John, McNamara, Sharon, Nielson, Dennis, Orenstein, David, O’Sullivan, Brian, Passero, Mary Ann, Perkett, Elizabeth, Spencer, Terry, Tabor, Holly K., Weiss, Robert, Wigley, Fred, Wise, Robert A., Wurfel, Mark M., Eichler, Evan E., Fu, Wenqing, Smith, Joshua D., Tennessen, Jacob A., Peters, Ulrike, Brzyski, Robert, Curb, J. David, Eaton, Charles B., Heiss, Gerardo, Johnson, Karen C., Lasser, Norman, Lin, Dan-Yu, Logsdon, Benjamin A., Manson, JoAnn E., Martin, Lisa, Stein, Evan, Applebaum-Bowden, Deborah, Paltoo, Dina N., Sturcke, Anne

Get full text

Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury by Guo, Zhen, Valenzuela Ripoll, Carla, Picataggi, Antonino, Rawnsley, David R., Ozcan, Mualla, Chirinos, Julio A., Chendamarai, Ezhilarasi, Girardi, Amanda, Riehl, Terrence, Evie, Hosannah, Diab, Ahmed, Kovacs, Attila, Hyrc, Krzysztof, Ma, Xiucui, Asnani, Aarti, Shewale, Swapnil V., Scherrer-Crosbie, Marielle, Cowart, Lauren Ashley, Parks, John S., Zhao, Lei, Gordon, David, Ramirez-Valle, Francisco, Margulies, Kenneth B., Cappola, Thomas P., Desai, Ankit A., Pedersen, Lauren N., Bergom, Carmen, Stitziel, Nathan O., Rettig, Michael P., DiPersio, John F., Hajny, Stefan, Christoffersen, Christina, Diwan, Abhinav, Javaheri, Ali

Get full text

Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset by Gordon, Adam S, Tabor, Holly K, Johnson, Andrew D, Snively, Beverly M, Assimes, Themistocles L, Auer, Paul L, Ioannidis, John P A, Peters, Ulrike, Robinson, Jennifer G, Sucheston, Lara E, Wang, Danxin, Sotoodehnia, Nona, Rotter, Jerome I, Psaty, Bruce M, Jackson, Rebecca D, Herrington, David M, O'Donnell, Christopher J, Reiner, Alexander P, Rich, Stephen S, Rieder, Mark J, Bamshad, Michael J, Nickerson, Deborah A

Get full text

Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population: e1004494 by Lim, Elaine T, Würtz, Peter, Havulinna, Aki S, Palta, Priit, Tukiainen, Taru, Rehnström, Karola, Esko, Tõnu, Mägi, Reedik, Inouye, Michael, Lappalainen, Tuuli, Chan, Yingleong, Salem, Rany M, Lek, Monkol, Flannick, Jason, Sim, Xueling, Manning, Alisa, Ladenvall, Claes, Bumpstead, Suzannah, Hämäläinen, Eija, Aalto, Kristiina, Maksimow, Mikael, Salmi, Marko, Blankenberg, Stefan, Ardissino, Diego, Shah, Svati, Horne, Benjamin, McPherson, Ruth, Hovingh, Gerald K, Reilly, Muredach P, Watkins, Hugh, Goel, Anuj, Farrall, Martin, Girelli, Domenico, Reiner, Alex P, Stitziel, Nathan O, Kathiresan, Sekar, Gabriel, Stacey, Barrett, Jeffrey C, Lehtimäki, Terho, Laakso, Markku, Groop, Leif, Kaprio, Jaakko, Perola, Markus, McCarthy, Mark I, Boehnke, Michael, Altshuler, David M, Lindgren, Cecilia M, Hirschhorn, Joel N, Metspalu, Andres, Freimer, Nelson B, Zeller, Tanja, Jalkanen, Sirpa, Koskinen, Seppo, Raitakari, Olli, Durbin, Richard, MacArthur, Daniel G, Salomaa, Veikko, Ripatti, Samuli, Daly, Mark J, Palotie, Aarno

Get full text