Secondary integrated analysis of multi-tissue transcriptomic responses to a combined lifestyle intervention in older adults from the GOTO nonrandomized trial by Bogaards, F. A., Gehrmann, T., Beekman, M., Lakenberg, N., Suchiman, H. E. D., de Groot, C. P. G. M., Reinders, M. J. T., Slagboom, P. E.

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Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants by Houtman, Evelyn, Tuerlings, Margo, Riechelman, Janne, Suchiman, Eka H. E. D, van der Wal, Robert J. P, Nelissen, Rob G. H. H, Mei, Hailiang, Ramos, Yolande F. M, Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid

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RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment T... by Tuerlings, Margo, Hoolwerff, Marcella, Houtman, Evelyn, Suchiman, Eka H. E. D., Lakenberg, Nico, Mei, Hailiang, Linden, Enrike H. M. J., Nelissen, Rob R. G. H. H., Ramos, Yolande Y. F. M., Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid

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Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K inhibitor wa... by Houtman, E., Coutinho de Almeida, R., Tuerlings, M., Suchiman, H.E.D., Broekhuis, D., Nelissen, R.G.H.H., Ramos, Y.F.M., van Meurs, J.B.J., Meulenbelt, I.

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WWP2 confers risk to osteoarthritis by affecting cartilage matrix deposition via hypoxia associated genes by Tuerlings, M., Janssen, G.M.C., Boone, I., van Hoolwerff, M., Rodriguez Ruiz, A., Houtman, E., Suchiman, H.E.D., van der Wal, R.J.P., Nelissen, R.G.H.H., Coutinho de Almeida, R., van Veelen, P.A., Ramos, Y.F.M., Meulenbelt, I.

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Short telomere length is associated with impaired cognitive performance in European ancestry cohorts by Hägg, S, Zhan, Y, Karlsson, R, Gerritsen, L, Ploner, A, van der Lee, S J, Broer, L, Deelen, J, Marioni, R E, Wong, A, Lundquist, A, Zhu, G, Hansell, N K, Sillanpää, E, Fedko, I O, Amin, N A, Beekman, M, de Craen, A J M, Degerman, S, Harris, S E, Kan, K-J, Martin-Ruiz, C M, Montgomery, G W, Adolfsson, A N, Reynolds, C A, Samani, N J, Suchiman, H E D, Viljanen, A, von Zglinicki, T, Wright, M J, Hottenga, J-J, Boomsma, D I, Rantanen, T, Kaprio, J A, Nyholt, D R, Martin, N G, Nyberg, L, Adolfsson, R, Kuh, D, Starr, J M, Deary, I J, Slagboom, P E, van Duijn, C M, Codd, V, Pedersen, N L

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Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes? by Middeldorp, C. M., Slof‐Op ‘t Landt, M. C. T., Medland, S. E., van Beijsterveldt, C. E. M., Bartels, M., Willemsen, G., Hottenga, J.‐J., de Geus, E. J. C., Suchiman, H. E. D., Dolan, C. V., Neale, M. C., Slagboom, P. E., Boomsma, D. I.

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Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls by Bot, Mariska, Milaneschi, Yuri, Al-Shehri, Tahani, Amin, Najaf, Garmaeva, Sanzhima, Onderwater, Gerrit L.J., Pool, Rene, Thesing, Carisha S., Vijfhuizen, Lisanne S., Vogelzangs, Nicole, Arts, Ilja C.W., Demirkan, Ayse, van Duijn, Cornelia, van Greevenbroek, Marleen, van der Kallen, Carla J.H., Köhler, Sebastian, Ligthart, Lannie, van den Maagdenberg, Arn M.J.M., Mook-Kanamori, Dennis O., de Mutsert, Renée, Tiemeier, Henning, Schram, Miranda T., Stehouwer, Coen D.A., Terwindt, Gisela M., Willems van Dijk, Ko, Fu, Jingyuan, Zhernakova, Alexandra, Beekman, Marian, Slagboom, P. Eline, Boomsma, Dorret I., Penninx, Brenda W.J.H., Beekman, M., Suchiman, H.E.D., Deelen, J., Amin, N., Beulens, J.W., van der Bom, J.A., Bomer, N., Demirkan, A., van Hilten, J.A., Meessen, J.M.T.A., Pool, R., Moed, M.H., Fu, J., Onderwater, G.L.J., Rutters, F., So-Osman, C., van der Flier, W.M., van der Heijden, A.A.W.A., van der Spek, A., Asselbergs, F.W., Boersma, E., Elders, P.M., Geleijnse, J.M., Ikram, M.A., Kloppenburg, M., Meulenbelt, I., Mooijaart, S.P., Nelissen, R.G.H.H., Netea, M.G., Penninx, B.W.J.H., Stehouwer, C.D.A., Teunissen, C.E., Terwindt, G.M., ’t Hart, L.M., van den Maagdenberg, A.M.J.M., van der Harst, P., van der Horst, I.C.C., van der Kallen, C.J.H., van Greevenbroek, M.M.J., van Spil, W.E., Wijmenga, C., Zwinderman, A.H., Zhernikova, A., Jukema, J.W., Sattar, N.

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A SNP panel for identification of DNA and RNA specimens by Yousefi, Soheil, Abbassi-Daloii, Tooba, Kraaijenbrink, Thirsa, Vermaat, Martijn, Mei, Hailiang, van 't Hof, Peter, van Iterson, Maarten, Zhernakova, Daria V, Claringbould, Annique, Franke, Lude, 't Hart, Leen M, Slieker, Roderick C, van der Heijden, Amber, de Knijff, Peter, 't Hoen, Peter A C

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NMR metabolomics-guided DNA methylation mortality predictors by Bizzarri, Daniele, Reinders, Marcel J.T., Kuiper, Lieke, Beekman, Marian, Deelen, Joris, van Meurs, Joyce B.J., van Dongen, Jenny, Pool, René, Boomsma, Dorret I., Ghanbari, Mohsen, Franke, Lude, Geleijnse, J.M., Boersma, E., van Spil, W.E., van Greevenbroek, M.M.J., Stehouwer, C.D.A., van der Kallen, C.J.H., Arts, I.C.W., Rutters, F., Beulens, J.W.J., Muilwijk, M., Elders, P.J.M., 't Hart, L.M., Ghanbari, M., Ikram, M.A., Netea, M.G., Kloppenburg, M., Ramos, Y.F.M., Bomer, N., Meulenbelt, I., Stronks, K., Snijder, M.B., Zwinderman, A.H., Heijmans, B.T., Lumey, L.H., Wijmenga, C., Fu, J., Zhernakova, A., Deelen, J., Mooijaart, S.P., Beekman, M., Slagboom, P.E., Onderwater, G.L.J., van den Maagdenberg, A.M.J.M., Terwindt, G.M., Thesing, C., Bot, M., Penninx, B.W.J.H., Trompet, S., Jukema, J.W., Sattar, N., van der Horst, I.C.C., van der Harst, P., So-Osman, C., van Hilten, J.A., Nelissen, R.G.H.H., Höfer, I.E., Asselbergs, F.W., Scheltens, P., Teunissen, C.E., van der Flier, W.M., van Dongen, J., Pool, R., Willemsen, A.H.M., Boomsma, D.I., Suchiman, H.E.D., Barkey Wolf, J.J.H., Cats, D., Mei, H., Slofstra, M., Swertz, M., Reinders, M.J.T., van den Akker, E.B., Slagboom, Pieternella E., van den Akker, Erik B.

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Skewed X-inactivation is common in the general female population by Shvetsova, Ekaterina, Sofronova, Alina, Monajemi, Ramin, Gagalova, Kristina, Draisma, Harmen H M, White, Stefan J, Santen, Gijs W E, Chuva de Sousa Lopes, Susana M, Heijmans, Bastiaan T, van Meurs, Joyce, Jansen, Rick, Franke, Lude, Kiełbasa, Szymon M, den Dunnen, Johan T, 't Hoen, Peter A C

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Genetic and environmental influences interact with age and sex in shaping the human methylome by van Dongen, Jenny, Nivard, Michel G., Willemsen, Gonneke, Hottenga, Jouke-Jan, Helmer, Quinta, Dolan, Conor V., Ehli, Erik A., Davies, Gareth E., van Iterson, Maarten, Breeze, Charles E., Beck, Stephan, Suchiman, H. Eka, Jansen, Rick, van Meurs, Joyce B., Heijmans, Bastiaan T., Slagboom, P. Eline, Boomsma, Dorret I.

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Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers by DEELEN, Joris, BEEKMAN, Marian, UITTERLINDEN, André G, HOFMAN, Albert, DE CRAEN, Anton J. M, METSPALU, Andres, PEDERSEN, Nancy L, VAN DUIJN, Cornelia M, WOUTER JUKEMA, J, HOUWING-DUISTERMAAT, Jeanine J, SAMANI, Nilesh J, SLAGBOOM, P. Eline, CODD, Veryan, TROMPET, Stella, BROER, Linda, HÄGG, Sara, FISCHER, Krista, THIJSSEN, Peter E, SUCHIMAN, H. Eka D, POSTMUS, Iris

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Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process by Bacalini, Maria Giulia, Deelen, Joris, Pirazzini, Chiara, De Cecco, Marco, Giuliani, Cristina, Lanzarini, Catia, Ravaioli, Francesco, Marasco, Elena, van Heemst, Diana, Suchiman, H Eka D, Slieker, Roderick, Giampieri, Enrico, Recchioni, Rina, Marcheselli, Fiorella, Salvioli, Stefano, Vitale, Giovanni, Olivieri, Fabiola, Spijkerman, Annemieke M W, Dollé, Martijn E T, Sedivy, John M, Castellani, Gastone, Franceschi, Claudio, Slagboom, Pieternella E, Garagnani, Paolo

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Selection for genetic variation inducing pro-inflammatory responses under adverse environmental conditions in a Ghanaian population by Kuningas, Maris, May, Linda, Tamm, Riin, van Bodegom, David, van den Biggelaar, Anita H J, Meij, Johannes J, Frölich, Marijke, Ziem, Juventus B, Suchiman, Helena E D, Metspalu, Andres, Slagboom, P Eline, Westendorp, Rudi G J

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Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium by van der Spek, Ashley, Broer, Linda, Draisma, Harmen H. M., Pool, René, Albrecht, Eva, Beekman, Marian, Mangino, Massimo, Raag, Mait, Nyholt, Dale R., Dharuri, Harish K., Codd, Veryan, Amin, Najaf, de Geus, Eco J. C., Deelen, Joris, Demirkan, Ayse, Yet, Idil, Fischer, Krista, Haller, Toomas, Henders, Anjali K., Isaacs, Aaron, Medland, Sarah E., Montgomery, Grant W., Mooijaart, Simon P., Strauch, Konstantin, Suchiman, H. Eka D., Vaarhorst, Anika A. M., van Heemst, Diana, Wang-Sattler, Rui, Whitfield, John B., Willemsen, Gonneke, Wright, Margaret J., Martin, Nicholas G., Samani, Nilesh J., Metspalu, Andres, Eline Slagboom, P., Spector, Tim D., Boomsma, Dorret I., van Duijn, Cornelia M., Gieger, Christian

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Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies by Hagenbeek, Fiona A., Pool, René, van Dongen, Jenny, Draisma, H. M., Jan Hottenga, Jouke, Willemsen, Gonneke, Abdellaoui, Abdel, Fedko, Iryna O., den Braber, Anouk, Visser, Pieter Jelle, de Geus, Eco J. C. N., Willems van Dijk, Ko, Verhoeven, Aswin, Suchiman, H. Eka, Beekman, Marian, Slagboom, P. Eline, van Duijn, Cornelia M., Harms, Amy C., Hankemeier, Thomas, Bartels, Meike, Nivard, Michel G., Boomsma, Dorret I.

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Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits by Porcu, Eleonora, Rüeger, Sina, Lepik, Kaido, Santoni, Federico A., Reymond, Alexandre, Kutalik, Zoltán

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DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation by Richard, Melissa A., Huan, Tianxiao, Ligthart, Symen, Gondalia, Rahul, Jhun, Min A., Brody, Jennifer A., Irvin, Marguerite R., Montasser, May E., Jia, Yucheng, Syme, Catriona, Salfati, Elias L., Boerwinkle, Eric, Guan, Weihua, Mosley, Thomas H., Bressler, Jan, Morrison, Alanna C., Liu, Chunyu, Mendelson, Michael M., Uitterlinden, André G., van Meurs, Joyce B., ’t Hoen, Peter A.C., van Meurs, Joyce, Isaacs, Aaron, Franke, Lude, Boomsma, Dorret I., Pool, René, Hottenga, Jouke J., van Greevenbroek, Marleen M.J., Stehouwer, Coen D.A., Wijmenga, Cisca, Zhernakova, Alexandra, Slagboom, P. Eline, Beekman, Marian, Deelen, Joris, van Heemst, Diana, Veldink, Jan H., van den Berg, Leonard H., van Duijn, Cornelia M., Hofman, Albert, Uitterlinden, André G., Jhamai, P. Mila, Verbiest, Michael, Suchiman, H. Eka D., Verkerk, Marijn, van der Breggen, Ruud, van Rooij, Jeroen, Lakenberg, Nico, Mei, Hailiang, van Iterson, Maarten, van Galen, Michiel, Bot, Jan, Nooren, Irene, Moed, Matthijs, Vermaat, Martijn, Zhernakova, Dasha V., Luijk, René, Bonder, Marc Jan, van Dijk, Freerk, Arindrarto, Wibowo, Kielbasa, Szymon M., Swertz, Morris A., van Zwet, Erik W., Franco, Oscar H., Zhang, Guosheng, Li, Yun, Stewart, James D., Bis, Joshua C., Psaty, Bruce M., Chen, Yii-Der Ida, Kardia, Sharon L.R., Zhao, Wei, Absher, Devin, Aslibekyan, Stella, Starr, John M., McRae, Allan F., Schwartz, Joel D., Vokonas, Pantel S., Menni, Cristina, Spector, Tim D., Shuldiner, Alan, Damcott, Coleen M., Rotter, Jerome I., Palmas, Walter, Liu, Yongmei, Paus, Tomáš, Horvath, Steve, O’Connell, Jeffrey R., Guo, Xiuqing, Pausova, Zdenka, Assimes, Themistocles L., Sotoodehnia, Nona, Smith, Jennifer A., Arnett, Donna K., Deary, Ian J., Baccarelli, Andrea A., Bell, Jordana T., Whitsel, Eric, Dehghan, Abbas, Levy, Daniel, Fornage, Myriam

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Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length by Li, Chen, Stoma, Svetlana, Lotta, Luca A., Warner, Sophie, Albrecht, Eva, Allione, Alessandra, Arp, Pascal P., Broer, Linda, Buxton, Jessica L., Da Silva Couto Alves, Alexessander, Deelen, Joris, Fedko, Iryna O., Gordon, Scott D., Jiang, Tao, Karlsson, Robert, Kerrison, Nicola, Loe, Taylor K., Mangino, Massimo, Milaneschi, Yuri, Miraglio, Benjamin, Pervjakova, Natalia, Russo, Alessia, Surakka, Ida, van der Spek, Ashley, Verhoeven, Josine E., Amin, Najaf, Beekman, Marian, Blakemore, Alexandra I., Canzian, Federico, Hamby, Stephen E., Hottenga, Jouke-Jan, Jones, Peter D., Jousilahti, Pekka, Mägi, Reedik, Medland, Sarah E., Montgomery, Grant W., Nyholt, Dale R., Perola, Markus, Pietiläinen, Kirsi H., Salomaa, Veikko, Sillanpää, Elina, Suchiman, H. Eka, van Heemst, Diana, Willemsen, Gonneke, Agudo, Antonio, Boeing, Heiner, Boomsma, Dorret I., Chirlaque, Maria-Dolores, Fagherazzi, Guy, Ferrari, Pietro, Franks, Paul, Gieger, Christian, Eriksson, Johan Gunnar, Gunter, Marc, Hägg, Sara, Hovatta, Iiris, Imaz, Liher, Kaprio, Jaakko, Kaaks, Rudolf, Key, Timothy, Krogh, Vittorio, Martin, Nicholas G., Melander, Olle, Metspalu, Andres, Moreno, Concha, Onland-Moret, N. Charlotte, Nilsson, Peter, Ong, Ken K., Overvad, Kim, Palli, Domenico, Panico, Salvatore, Pedersen, Nancy L., Penninx, Brenda W.J. H., Quirós, J. Ramón, Jarvelin, Marjo Riitta, Rodríguez-Barranco, Miguel, Scott, Robert A., Severi, Gianluca, Slagboom, P. Eline, Spector, Tim D., Tjonneland, Anne, Trichopoulou, Antonia, Tumino, Rosario, Uitterlinden, André G., van der Schouw, Yvonne T., van Duijn, Cornelia M., Weiderpass, Elisabete, Denchi, Eros Lazzerini, Matullo, Giuseppe, Butterworth, Adam S., Danesh, John, Samani, Nilesh J., Wareham, Nicholas J., Nelson, Christopher P., Langenberg, Claudia, Codd, Veryan

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