Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase by Singh, Amrita, Ottavi, Samantha, Krieger, Inna, Planck, Kyle, Perkowski, Andrew, Kaneko, Takushi, Davis, Andrew M, Suh, Christine, Zhang, David, Goullieux, Laurent, Alex, Alexander, Roubert, Christine, Gardner, Mark, Preston, Marian, Smith, Dave M, Ling, Yan, Roberts, Julia, Cautain, Bastien, Upton, Anna, Cooper, Christopher B, Serbina, Natalya, Tanvir, Zaid, Mosior, John, Ouerfelli, Ouathek, Yang, Guangli, Gold, Ben S, Rhee, Kyu Y, Sacchettini, James C, Fotouhi, Nader, Aubé, Jeffrey, Nathan, Carl

Get full text

Synthesis and antibacterial activity of C11, C12-cyclic urea analogues of ketolides by Kaneko, Takushi, McMillen, William, Lynch, Meghan Keaney

Get full text

Novel tethers in ketolide antibiotics by Kaneko, Takushi, Romero, Karina, Li, Bryan, Buzon, Richard

Get full text

Carbonic anhydrase II was detected in urine of a patient with osteosarcoma during high-dose methotrexate and leucovorin rescue therapy by Sato, Toyoji, Kaneko, Takushi, Ishikawa, Naoko, Toyama, Takako, Enomoto, Shinichi, Ohashi, Tatsuya, Shima, Yukio, Kimura, Akira, Hatano, Hiroshi, Uchiyama, Toru, Segawa, Hiroyuki, Kobayashi, Hiroto, Morita, Tetsuro

Get full text

Discovery of Azetidinyl Ketolides for the Treatment of Susceptible and Multidrug Resistant Community-Acquired Respiratory Tract Infections by Magee, Thomas V, Ripp, Sharon L, Li, Bryan, Buzon, Richard A, Chupak, Lou, Dougherty, Thomas J, Finegan, Steven M, Girard, Dennis, Hagen, Anne E, Falcone, Michael J, Farley, Kathleen A, Granskog, Karl, Hardink, Joel R, Huband, Michael D, Kamicker, Barbara J, Kaneko, Takushi, Knickerbocker, Michael J, Liras, Jennifer L, Marra, Andrea, Medina, Ivy, Nguyen, Thuy-Trinh, Noe, Mark C, Obach, R. Scott, O’Donnell, John P, Penzien, Joseph B, Reilly, Usa Datta, Schafer, John R, Shen, Yue, Stone, Gregory G, Strelevitz, Timothy J, Sun, Jianmin, Tait-Kamradt, Amelia, Vaz, Alfin D. N, Whipple, David A, Widlicka, Daniel W, Wishka, Donn G, Wolkowski, Joanna P, Flanagan, Mark E

Get full text

Possible biomimetic synthesis of .beta.-lactams by Kaneko, Takushi

Get full text

Pyripyropenes, novel ACAT inhibitors produced by Aspergillus fumigatus. III: Structure elucidation of pyripyropenes E to L by TOMODA, H, TABATA, N, DA-JUN YANG, TAKAYANAGI, H, NISHIDA, H, OMURA, S, KANEKO, T

Get full text

Identification of a small molecule with activity against drug-resistant and persistent tuberculosis by Wang, Feng, Sambandan, Dhinakaran, Halder, Rajkumar, Wang, Jianing, Batt, Sarah M., Weinrick, Brian, Ahmad, Insha, Yang, Pengyu, Zhang, Yong, Kim, John, Hassani, Morad, Huszar, Stanislav, Trefzer, Claudia, Ma, Zhenkun, Kaneko, Takushi, Mdluli, Khisi E., Franzblau, Scott, Chatterjee, Arnab K., Johnson, Kai, Mikusova, Katarina, Besra, Gurdyal S., Fütterer, Klaus, Jacobs, William R., Schultz, Peter G.

Get full text

Pyripyropenes, novel ACAT inhibitors produced by Aspergillus fumigatus. IV. Structure elucidation of pyripyropenes M to R by TOMODA, H, TABATA, N, DA-JUN YANG, NAMATAME, I, TANAKA, H, OMURA, S, KANEKO, T

Get full text

Synthesis and SAR of novel conformationally-restricted oxazolidinones possessing Gram-positive and fastidious Gram-negative antibacterial activity. Part 1: Substituted pyrazoles by Boyer, Frederick E., Vara Prasad, J.V.N., Choy, Allison L., Chupak, Louis, Dermyer, Michael R., Ding, Qizhu, Huband, Michael D., Jiao, Wenhua, Kaneko, Takushi, Khlebnikov, Vladimir, Kim, Ji-Young, Lall, Manjinder S., Maiti, Samarendra N., Romero, Karina, Wu, Xiujuan

Get full text

Generation of Novel Rapamycin Structures by Microbial Manipulations by NLSHIDA, HLROYUKI, SAKAKIBARA, TATSUO, AOKI, FUKUMATSU, SAITO, TOSHIYUKI, ICHIKAWA, KATSUOMI, INAGAKI, TAISUKE, KOJIMA, YASUHIRO, YAMAUCHI, YUJI, HUANG, LIANG H., GUADLIANA, MARK A., KANEKO, TAKUSHI, KOJIMA, NAKAO

Get full text

Analysis and hit filtering of a very large library of compounds screened against Mycobacterium tuberculosisElectronic supplementary information (ESI) available: Supplementary figur... by Ekins, Sean, Kaneko, Takushi, Lipinski, Christopher A, Bradford, Justin, Dole, Krishna, Spektor, Anna, Gregory, Kellan, Blondeau, David, Ernst, Sylvia, Yang, Jeremy, Goncharoff, Nicko, Hohman, Moses M, Bunin, Barry A

Get full text

CP-225,917 and CP-263,114:  Novel Ras Farnesylation Inhibitors from an Unidentified Fungus. 2. Structure Elucidation by Dabrah, Thomas T, Kaneko, Takushi, Massefski, Walter, Whipple, Earl B

Get full text

New hydrazone derivatives of Adriamycin and their immunoconjugates - a correlation between acid stability and cytotoxicity by Kaneko, Takushi, Willner, David, Monkovic, Ivo, Knipe, Jay O, Braslawsky, Gary R, Greenfield, Robert S, Vyas, Dolatrai M

Get full text

Evaluation in vitro of adriamycin immunoconjugates synthesized using an acid-sensitive hydrazone linker by GREENFIELD, R. S, KANEKO, T, DAUES, A, EDSON, M. A, FITZGERALD, K. A, OLECH, L. J, GRATTAN, A, SPITALNY, G. L, BRASLAWSKY, G. R

Get full text

WATER SOLUBLE DERIVATIVES OF REBECCAMYCIN by KANEKO, TAKUSHI, WONG, HENRY, UTZIG, JACOB, SCHURIG, JOHN, DOYLE, TERRENCE W.

Get full text

New and efficient approach to functionalized hydroazulenes via 2-methylcyclopentenone 3-dimethylsulfoxonium methylide by Marino, Joseph P, Kaneko, Takushi

Get full text

Biosynthesis of Pyripyropene A by Tomoda, Hiroshi, Tabata, Noriko, Nakata, Yumi, Nishida, Hiroyuki, Kaneko, Takushi, Obata, Rika, Sunazuka, Toshiaki, Ōmura, Satoshi

Get full text

Antitumor activity of adriamycin (hydrazone-linked) immunoconjugates compared with free adriamycin and specificity of tumor cell killing by BRASLAWSKY, G. R, EDSON, M.A, PEARCE, W, KANEKO, T, GREENFIELD, R. S

Get full text

Adriamycin(hydrazone)-antibody conjugates require internalization and intracellular acid hydrolysis for antitumor activity by BRASLAWSKY, G. R, KADOW, K, KNIPE, J, MCGOFF, K, EDSON, M, KANEKO, T, GREENFIELD, R. S

Get full text