Discovery and biochemical characterization of selective ATP competitive inhibitors of the human mitotic kinesin KSP by Rickert, Keith W., Schaber, Michael, Torrent, Maricel, Neilson, Lou Anne, Tasber, Edward S., Garbaccio, Robert, Coleman, Paul J., Harvey, Diane, Zhang, Yun, Yang, Yi, Marshall, Gary, Lee, Ling, Walsh, Eileen S., Hamilton, Kelly, Buser, Carolyn A.

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Optimization of a pyrazoloquinolinone class of Chk1 kinase inhibitors by Brnardic, Edward J., Garbaccio, Robert M., Fraley, Mark E., Tasber, Edward S., Steen, Justin T., Arrington, Kenneth L., Dudkin, Vadim Y., Hartman, George D., Stirdivant, Steven M., Drakas, Bob A., Rickert, Keith, Walsh, Eileen S., Hamilton, Kelly, Buser, Carolyn A., Hardwick, James, Tao, Weikang, Beck, Stephen C., Mao, Xianzhi, Lobell, Robert B., Sepp-Lorenzino, Laura, Yan, Youwei, Ikuta, Mari, Munshi, Sanjeev K., Kuo, Lawrence C., Kreatsoulas, Constantine

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Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP by Garbaccio, Robert M., Tasber, Edward S., Neilson, Lou Anne, Coleman, Paul J., Fraley, Mark E., Olson, Christy, Bergman, Jeff, Torrent, Maricel, Buser, Carolyn A., Rickert, Keith, Walsh, Eileen S., Hamilton, Kelly, Lobell, Robert B., Tao, Weikang, South, Vicki J., Diehl, Ronald E., Davide, Joseph P., Yan, Youwei, Kuo, Lawrence C., Li, Chunze, Prueksaritanont, Thomayant, Fernandez-Metzler, Carmen, Mahan, Elizabeth A., Slaughter, Donald E., Salata, Joseph J., Kohl, Nancy E., Huber, Hans E., Hartman, George D.

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Kinesin spindle protein (KSP) inhibitors. Part 2: The design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP by Fraley, Mark E., Garbaccio, Robert M., Arrington, Kenneth L., Hoffman, William F., Tasber, Edward S., Coleman, Paul J., Buser, Carolyn A., Walsh, Eileen S., Hamilton, Kelly, Fernandes, Christine, Schaber, Michael D., Lobell, Robert B., Tao, Weikang, South, Victoria J., Yan, Youwei, Kuo, Lawrence C., Prueksaritanont, Thomayant, Shu, Cathy, Torrent, Maricel, Heimbrook, David C., Kohl, Nancy E., Huber, Hans E., Hartman, George D.

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Kinesin spindle protein (KSP) inhibitors. Part 3: Synthesis and evaluation of phenolic 2,4-diaryl-2,5-dihydropyrroles with reduced hERG binding and employment of a phosphate prodru... by Garbaccio, Robert M., Fraley, Mark E., Tasber, Edward S., Olson, Christy M., Hoffman, William F., Arrington, Kenneth L., Torrent, Maricel, Buser, Carolyn A., Walsh, Eileen S., Hamilton, Kelly, Schaber, Michael D., Fernandes, Christine, Lobell, Robert B., Tao, Weikang, South, Vicki J., Yan, Youwei, Kuo, Lawrence C., Prueksaritanont, Thomayant, Slaughter, Donald E., Shu, Cathy, Heimbrook, David C., Kohl, Nancy E., Huber, Hans E., Hartman, George D.

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Stereospecific reduction of a potent kinesin spindle protein (KSP) inhibitor in human tissues by Li, Chunze, Lu, Bing, Garbaccio, Robert M., Tasber, Edward S., Fraley, Mark E., Hartman, George D., Ye, Jingjing, Harrelson, Jane C., Prueksaritanont, Thomayant

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Thermodynamic equilibration of dihydropyridone enolates: application to the total synthesis of (+/−)-epiuleine by Tasber, Edward S., Garbaccio, Robert M.

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Synthesis and evaluation of substituted benzoisoquinolinones as potent inhibitors of Chk1 kinase by Garbaccio, Robert M., Huang, Shaei, Tasber, Edward S., Fraley, Mark E., Yan, Youwei, Munshi, Sanjeev, Ikuta, Mari, Kuo, Lawrence, Kreatsoulas, Constanine, Stirdivant, Steve, Drakas, Bob, Rickert, Keith, Walsh, Eileen S., Hamilton, Kelly A., Buser, Carolyn A., Hardwick, James, Mao, Xianzhi, Beck, Stephen C., Abrams, Marc T., Tao, Weikang, Lobell, Rob, Sepp-Lorenzino, Laura, Hartman, George D.

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Design and synthesis of 3,7-diarylimidazopyridines as inhibitors of the VEGF-receptor KDR by ZHICAI WU, FRALEY, Mark E, BIN SHI, SEPP-LORENZINO, Laura, THOMAS, Kenneth A, BILODEAU, Mark T, KAUFMAN, Mildred L, TASBER, Edward S, BALITZA, Adrienne E, HARTMAN, George D, COLL, Kathleen E, RICKERT, Keith, SHIPMAN, Jennifer

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Biochemical Characterization of a Class of Inhibitors of the Human Mitotic Kinesin KSP with a Novel Mechanism of Action by Rickert, Keith W, Schaber, Michael D, Torrent, Maricel, Neilson, Lou Anne, Tasber, Edward S, Garbaccio, Robert M, Coleman, Paul J, Harvey, Diane, Zhang, Yun, Yang, Yi, Marshall, Gary, Lee, Ling, Walsh, Eileen S, Hamilton, Kelly, Buser, Carolyn

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Optimization of a pyrazoloquinolinone class of Chkl kinase inhibitors by BRNARDIC, Edward J, GARBACCIO, Robert M, RICKERT, Keith, WALSH, Eileen S, HAMILTON, Kelly, BUSER, Carolyn A, HARDWICK, James, WEIKANG TAO, BECK, Stephen C, XIANZHI MAO, LOBELL, Robert B, SEPP-LORENZINO, Laura, FRALEY, Mark E, YOUWEI YAN, IKUTA, Mari, MUNSHI, Sanjeev K, KUO, Lawrence C, KREATSOULAS, Constantine, TASBER, Edward S, STEEN, Justin T, ARRINGTON, Kenneth L, DUDKIN, Vadim Y, HARTMAN, George D, STIRDIVANT, Steven M, DRAKAS, Bob A

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Development of thioquinazolinones, allosteric Chk1 kinase inhibitors by Converso, Antonella, Hartingh, Timothy, Garbaccio, Robert M., Tasber, Edward, Rickert, Keith, Fraley, Mark E., Yan, Youwei, Kreatsoulas, Constantine, Stirdivant, Steve, Drakas, Bob, Walsh, Eileen S., Hamilton, Kelly, Buser, Carolyn A., Mao, Xianzhi, Abrams, Marc T., Beck, Stephen C., Tao, Weikang, Lobell, Rob, Sepp-Lorenzino, Laura, Zugay-Murphy, Joan, Sardana, Vinod, Munshi, Sanjeev K., Jezequel-Sur, Sylvie Marie, Zuck, Paul D., Hartman, George D.

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