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Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5‑b]pyridazines for the Treatment of Human African Trypanosomiasis
by
Tear, Westley F
,
Bag, Seema
,
Diaz-Gonzalez, Rosario
,
Ceballos-Pérez, Gloria
,
Rojas-Barros, Domingo I
,
Cordon-Obras, Carlos
,
Pérez-Moreno, Guiomar
,
García-Hernández, Raquel
,
Martinez-Martinez, Maria Santos
,
Ruiz-Perez, Luis Miguel
,
Gamarro, Francisco
,
Gonzalez Pacanowska, Dolores
,
Caffrey, Conor R
,
Ferrins, Lori
,
Manzano, Pilar
,
Navarro, Miguel
,
Pollastri, Michael P
Published in
Journal of medicinal chemistry
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Structure-property studies of an imidazoquinoline chemotype with antitrypanosomal activity
by
Klug, Dana M
,
Diaz-Gonzalez, Rosario
,
DeLano, Travis J
,
Mavrogiannaki, Eftychia M
,
Buskes, Melissa J
,
Dalton, Raeann M
,
Fisher, John K
,
Schneider, Katherine M
,
Hilborne, Vivian
,
Fritsche, Melanie G
,
Simpson, Quillon J
,
Tear, Westley F
,
Devine, William G
,
Pérez-Moreno, Guiomar
,
Ceballos-Pérez, Gloria
,
García-Hernández, Raquel
,
Bosch-Navarrete, Cristina
,
Ruiz-Pérez, Luis Miguel
,
Gamarro, Francisco
,
González-Pacanowska, Dolores
,
Martinez-Martinez, Maria Santos
,
Manzano-Chinchon, Pilar
,
Navarro, Miguel
,
Pollastri, Michael P
,
Ferrins, Lori
Published in
RSC medicinal chemistry
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Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library
by
Rowley, Ann M.
,
Yao, Gang
,
Andrews, Logan
,
Bedermann, Aaron
,
Biddulph, Ross
,
Bingham, Ryan
,
Brady, Jennifer J.
,
Buxton, Rachel
,
Cecconie, Ted
,
Cooper, Rona
,
Csakai, Adam
,
Gao, Enoch N.
,
Grenier-Davies, Melissa C.
,
Lawler, Meghan
,
Lian, Yiqian
,
Macina, Justyna
,
Macphee, Colin
,
Marcaurelle, Lisa
,
Martin, John
,
McCormick, Patricia
,
Pindoria, Rekha
,
Rauch, Martin
,
Rocque, Warren
,
Shen, Yingnian
,
Shewchuk, Lisa M.
,
Squire, Michael
,
Stebbeds, Will
,
Tear, Westley
,
Wang, Xin
,
Ward, Paris
,
Xiao, Shouhua
Published in
Journal of medicinal chemistry
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Corrigendum: Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes
by
Ferrins, Lori
,
Buskes, Melissa J.
,
Kapteyn, Madison M.
,
Engels, Hannah N.
,
Enos, Suzanne E.
,
Lu, Chenyang
,
Klug, Dana M.
,
Singh, Baljinder
,
Quotadamo, Antonio
,
Bachovchin, Kelly
,
Tear, Westley F.
,
Spaulding, Andrew E.
,
Forbes, Katherine C.
,
Bag, Seema
,
Rivers, Mitch
,
LeBlanc, Catherine
,
Burchfield, Erin
,
Armand, Jeremy R.
,
Diaz-Gonzalez, Rosario
,
Ceballos-Perez, Gloria
,
García-Hernández, Raquel
,
Pérez-Moreno, Guiomar
,
Bosch-Navarrete, Cristina
,
Gómez-Liñán, Claudia
,
Ruiz-Pérez, Luis Miguel
,
Gamarro, Francisco
,
González-Pacanowska, Dolores
,
Navarro, Miguel
,
Mensa-Wilmot, Kojo
,
Pollastri, Michael P.
,
Kyle, Dennis E.
,
Rice, Christopher A.
Published in
Frontiers in microbiology
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Compound design guidelines for evading the efflux and permeation barriers of Escherichia coli with the oxazolidinone class of antibacterials: Test case for a general approach to im...
by
Spaulding, Andrew
,
Takrouri, Khuloud
,
Mahalingam, Pornachandran
,
Cleary, Dillon C.
,
Cooper, Harold D.
,
Zucchi, Paola
,
Tear, Westley
,
Koleva, Bilyana
,
Beuning, Penny J.
,
Hirsch, Elizabeth B.
,
Aggen, James B.
Published in
Bioorganic & medicinal chemistry letters
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Progress against Escherichia coli with the Oxazolidinone Class of Antibacterials: Test Case for a General Approach To Improving Whole-Cell Gram-Negative Activity
by
Takrouri, Khuloud
,
Cooper, Harold D
,
Spaulding, Andrew
,
Zucchi, Paola
,
Koleva, Bilyana
,
Cleary, Dillon C
,
Tear, Westley
,
Beuning, Penny J
,
Hirsch, Elizabeth B
,
Aggen, James B
Published in
ACS infectious diseases
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From Cells to Mice to Target: Characterization of NEU-1053 (SB-443342) and Its Analogues for Treatment of Human African Trypanosomiasis
by
Devine, William G
,
Diaz-Gonzalez, Rosario
,
Ceballos-Perez, Gloria
,
Rojas, Domingo
,
Satoh, Takashi
,
Tear, Westley
,
Ranade, Ranae M
,
Barros-Álvarez, Ximena
,
Hol, Wim G. J
,
Buckner, Frederick S
,
Navarro, Miguel
,
Pollastri, Michael P
Published in
ACS infectious diseases
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Structure–property studies of an imidazoquinoline chemotype with antitrypanosomal activity† †Electronic supplementary information (ESI) available. See DOI: 10.1039/d0md00103a
by
Klug, Dana M.
,
Diaz-Gonzalez, Rosario
,
DeLano, Travis J.
,
Mavrogiannaki, Eftychia M.
,
Buskes, Melissa J.
,
Dalton, Raeann M.
,
Fisher, John K.
,
Schneider, Katherine M.
,
Hilborne, Vivian
,
Fritsche, Melanie G.
,
Simpson, Quillon J.
,
Tear, Westley F.
,
Devine, William G.
,
Pérez-Moreno, Guiomar
,
Ceballos-Pérez, Gloria
,
García-Hernández, Raquel
,
Bosch-Navarrete, Cristina
,
Ruiz-Pérez, Luis Miguel
,
Gamarro, Francisco
,
González-Pacanowska, Dolores
,
Martinez-Martinez, Maria Santos
,
Manzano-Chinchon, Pilar
,
Navarro, Miguel
,
Pollastri, Michael P.
,
Ferrins, Lori
Published in
RSC medicinal chemistry
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