BMPER variants associated with a novel, attenuated subtype of diaphanospondylodysostosis by Zong, Zheyuan, Tees, Susan, Miyanji, Firoz, Fauth, Clarissa, Reilly, Christopher, Lopez, Elena, Tredwell, Stephen, Paul Goldberg, Yigal, Delaney, Allen, Eydoux, Patrice, Van Allen, Margot, Lehman, Anna

Get full text

Leisure time physical activity of moderate to vigorous intensity and mortality: a large pooled cohort analysis by Moore, Steven C, Patel, Alpa V, Matthews, Charles E, Berrington de Gonzalez, Amy, Park, Yikyung, Katki, Hormuzd A, Linet, Martha S, Weiderpass, Elisabete, Visvanathan, Kala, Helzlsouer, Kathy J, Thun, Michael, Gapstur, Susan M, Hartge, Patricia, Lee, I-Min

Get full text

Association between class III obesity (BMI of 40-59 kg/m2) and mortality: a pooled analysis of 20 prospective studies by Kitahara, Cari M, Flint, Alan J, Berrington de Gonzalez, Amy, Bernstein, Leslie, Brotzman, Michelle, MacInnis, Robert J, Moore, Steven C, Robien, Kim, Rosenberg, Philip S, Singh, Pramil N, Weiderpass, Elisabete, Adami, Hans Olov, Anton-Culver, Hoda, Ballard-Barbash, Rachel, Buring, Julie E, Freedman, D Michal, Fraser, Gary E, Beane Freeman, Laura E, Gapstur, Susan M, Gaziano, John Michael, Giles, Graham G, Håkansson, Niclas, Hoppin, Jane A, Hu, Frank B, Koenig, Karen, Linet, Martha S, Park, Yikyung, Patel, Alpa V, Purdue, Mark P, Schairer, Catherine, Sesso, Howard D, Visvanathan, Kala, White, Emily, Wolk, Alicja, Zeleniuch-Jacquotte, Anne, Hartge, Patricia

Get full text

Mechanisms of Functional Mitral Regurgitation in Ischemic Cardiomyopathy Determined by Transesophageal Echocardiography (from the Surgical Treatment for Ischemic Heart Failure Tria... by Golba, Krzysztof, MD, Mokrzycki, Krzysztof, MD, PhD, Drozdz, Jaroslaw, MD, Cherniavsky, Alexander, MD, Wrobel, Krzysztof, MD, Roberts, Bradley J., MD, Haddad, Haissam, MD, Maurer, Gerald, MD, Yii, Michael, MB, MS, Asch, Federico M., MD, Handschumacher, Mark D., BS, Holly, Thomas A., MD, Przybylski, Roman, MD, Kron, Irving, MD, Schaff, Hartzell, MD, Aston, Susan, RN, Horton, John, MS, Lee, Kerry L., PhD, Velazquez, Eric J., MD, Grayburn, Paul A., MD

Get full text

Association analyses identify 31 new risk loci for colorectal cancer susceptibility by Law, Philip J., Timofeeva, Maria, Fernandez-Rozadilla, Ceres, Broderick, Peter, Studd, James, Fernandez-Tajes, Juan, Farrington, Susan, Svinti, Victoria, Palles, Claire, Orlando, Giulia, Sud, Amit, Holroyd, Amy, Penegar, Steven, Theodoratou, Evropi, Vaughan-Shaw, Peter, Campbell, Harry, Zgaga, Lina, Hayward, Caroline, Campbell, Archie, Harris, Sarah, Deary, Ian J., Starr, John, Gatcombe, Laura, Pinna, Maria, Briggs, Sarah, Martin, Lynn, Jaeger, Emma, Sharma-Oates, Archana, East, James, Leedham, Simon, Arnold, Roland, Johnstone, Elaine, Wang, Haitao, Kerr, David, Kerr, Rachel, Maughan, Tim, Kaplan, Richard, Al-Tassan, Nada, Palin, Kimmo, Hänninen, Ulrika A., Cajuso, Tatiana, Tanskanen, Tomas, Kondelin, Johanna, Kaasinen, Eevi, Sarin, Antti-Pekka, Eriksson, Johan G., Rissanen, Harri, Knekt, Paul, Pukkala, Eero, Jousilahti, Pekka, Salomaa, Veikko, Ripatti, Samuli, Palotie, Aarno, Renkonen-Sinisalo, Laura, Lepistö, Anna, Böhm, Jan, Mecklin, Jukka-Pekka, Buchanan, Daniel D., Win, Aung-Ko, Hopper, John, Jenkins, Mark E., Lindor, Noralane M., Newcomb, Polly A., Gallinger, Steven, Duggan, David, Casey, Graham, Hoffmann, Per, Nöthen, Markus M., Jöckel, Karl-Heinz, Easton, Douglas F., Pharoah, Paul D. P., Peto, Julian, Canzian, Federico, Swerdlow, Anthony, Eeles, Rosalind A., Kote-Jarai, Zsofia, Muir, Kenneth, Pashayan, Nora, Harkin, Andrea, Allan, Karen, McQueen, John, Paul, James, Iveson, Timothy, Saunders, Mark, Butterbach, Katja, Chang-Claude, Jenny, Hoffmeister, Michael, Brenner, Hermann, Kirac, Iva, Matošević, Petar, Hofer, Philipp, Brezina, Stefanie, Gsur, Andrea, Cheadle, Jeremy P., Aaltonen, Lauri A., Tomlinson, Ian, Houlston, Richard S., Dunlop, Malcolm G.

Get full text

Association of Cardiometabolic Multimorbidity With Mortality by Di Angelantonio, Emanuele, Kaptoge, Stephen, Wormser, David, Willeit, Peter, Butterworth, Adam S, Bansal, Narinder, O’Keeffe, Linda M, Gao, Pei, Wood, Angela M, Burgess, Stephen, Freitag, Daniel F, Pennells, Lisa, Peters, Sanne A, Hart, Carole L, Håheim, Lise Lund, Gillum, Richard F, Nordestgaard, Børge G, Psaty, Bruce M, Yeap, Bu B, Knuiman, Matthew W, Nietert, Paul J, Kauhanen, Jussi, Salonen, Jukka T, Kuller, Lewis H, Simons, Leon A, van der Schouw, Yvonne T, Barrett-Connor, Elizabeth, Selmer, Randi, Crespo, Carlos J, Rodriguez, Beatriz, Verschuren, W. M. Monique, Salomaa, Veikko, Svärdsudd, Kurt, van der Harst, Pim, Björkelund, Cecilia, Wilhelmsen, Lars, Wallace, Robert B, Brenner, Hermann, Amouyel, Philippe, Barr, Elizabeth L. M, Iso, Hiroyasu, Onat, Altan, Trevisan, Maurizio, D'Agostino, Ralph B, Cooper, Cyrus, Kavousi, Maryam, Welin, Lennart, Roussel, Ronan, Hu, Frank B, Sato, Shinichi, Davidson, Karina W, Howard, Barbara V, Leening, Maarten J. G, Rosengren, Annika, Dörr, Marcus, Deeg, Dorly J. H, Kiechl, Stefan, Stehouwer, Coen D. A, Nissinen, Aulikki, Giampaoli, Simona, Donfrancesco, Chiara, Kromhout, Daan, Price, Jackie F, Peters, Annette, Meade, Tom W, Casiglia, Edoardo, Lawlor, Debbie A, Gallacher, John, Nagel, Dorothea, Franco, Oscar H, Assmann, Gerd, Dagenais, Gilles R, Jukema, J. Wouter, Sundström, Johan, Woodward, Mark, Brunner, Eric J, Khaw, Kay-Tee, Wareham, Nicholas J, Whitsel, Eric A, Njølstad, Inger, Hedblad, Bo, Wassertheil-Smoller, Sylvia, Engström, Gunnar, Rosamond, Wayne D, Selvin, Elizabeth, Sattar, Naveed, Thompson, Simon G, Danesh, John

Get full text

An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk by Wu, Lang, Yang, Yaohua, Guo, Xingyi, Shu, Xiao-Ou, Cai, Qiuyin, Shu, Xiang, Li, Bingshan, Tao, Ran, Wu, Chong, Nikas, Jason B., Sun, Yanfa, Zhu, Jingjing, Roobol, Monique J., Giles, Graham G., Brenner, Hermann, John, Esther M., Clements, Judith, Grindedal, Eli Marie, Park, Jong Y., Stanford, Janet L., Kote-Jarai, Zsofia, Haiman, Christopher A., Eeles, Rosalind A., Zheng, Wei, Long, Jirong

Get full text

Adjunctive Pascolizumab in Rifampicin-Susceptible Pulmonary Tuberculosis: Proof-of-Concept, Partially-Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Trial by Paton, Nicholas I, Gurumurthy, Meera, Lu, Qingshu, Leek, Francesca, Kwan, Philip, Koh, Hiromi W L, Molton, James, Mortera, Lalaine, Naval, Sullian, Bakar, Zamzurina Abu, Pang, Yong-Kek, Lum, Lionel, Lim, Tow Keang, Cross, Gail B, Lekurwale, Ganesh, Choi, Hyungwon, Au, Veonice, Connolly, John, Hibberd, Martin, Green, Justin A

Get full text

Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies by Pennells, Lisa, Kaptoge, Stephen, Wood, Angela, Sweeting, Mike, Zhao, Xiaohui, White, Ian, Burgess, Stephen, Willeit, Peter, Bolton, Thomas, Moons, Karel G M, van der Schouw, Yvonne T, Selmer, Randi, Khaw, Kay-Tee, Gudnason, Vilmundur, Assmann, Gerd, Amouyel, Philippe, Salomaa, Veikko, Kivimaki, Mika, Nordestgaard, Børge G, Blaha, Michael J, Kuller, Lewis H, Brenner, Hermann, Gillum, Richard F, Meisinger, Christa, Ford, Ian, Knuiman, Matthew W, Rosengren, Annika, Lawlor, Debbie A, Völzke, Henry, Cooper, Cyrus, Marín Ibañez, Alejandro, Casiglia, Edoardo, Kauhanen, Jussi, Cooper, Jackie A, Rodriguez, Beatriz, Sundström, Johan, Barrett-Connor, Elizabeth, Dankner, Rachel, Nietert, Paul J, Davidson, Karina W, Wallace, Robert B, Blazer, Dan G, Björkelund, Cecilia, Donfrancesco, Chiara, Krumholz, Harlan M, Nissinen, Aulikki, Davis, Barry R, Coady, Sean, Whincup, Peter H, Jørgensen, Torben, Ducimetiere, Pierre, Trevisan, Maurizio, Engström, Gunnar, Crespo, Carlos J, Meade, Tom W, Visser, Marjolein, Kromhout, Daan, Kiechl, Stefan, Daimon, Makoto, Price, Jackie F, Gómez de la Cámara, Agustin, Wouter Jukema, J, Lamarche, Benoît, Onat, Altan, Simons, Leon A, Kavousi, Maryam, Ben-Shlomo, Yoav, Gallacher, John, Dekker, Jacqueline M, Arima, Hisatomi, Shara, Nawar, Tipping, Robert W, Roussel, Ronan, Brunner, Eric J, Koenig, Wolfgang, Sakurai, Masaru, Pavlovic, Jelena, Gansevoort, Ron T, Nagel, Dorothea, Goldbourt, Uri, Barr, Elizabeth L M, Palmieri, Luigi, Njølstad, Inger, Sato, Shinichi, Monique Verschuren, W M, Varghese, Cherian V, Graham, Ian, Onuma, Oyere, Greenland, Philip, Woodward, Mark, Ezzati, Majid, Psaty, Bruce M, Sattar, Naveed, Jackson, Rod, Ridker, Paul M, Cook, Nancy R, D'Agostino, Ralph B, Thompson, Simon G, Danesh, John, Di Angelantonio, Emanuele

Get full text

Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan by Hollis, Ben, Day, Felix R., Busch, Alexander S., Thompson, Deborah J., Soares, Ana Luiza G., Timmers, Paul R. H. J., Kwong, Alex, Easton, Doug F., Joshi, Peter K., Timpson, Nicholas J., Ong, Ken K., Perry, John R. B.

Get full text

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions by Mancuso, Nicholas, Gayther, Simon, Gusev, Alexander, Zheng, Wei, Penney, Kathryn L., Kote-Jarai, Zsofia, Eeles, Rosalind, Freedman, Matthew, Haiman, Christopher, Pasaniuc, Bogdan

Get full text

NX-2127-001, a First-in-Human Trial of NX-2127, a Bruton's Tyrosine Kinase-Targeted Protein Degrader, in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia and B-Cel... by Mato, Anthony R., Wierda, William G., Ai, Weiyun Z., Flinn, Ian W., Tees, Michael, Patel, Manish R., Patel, Krish, O'Brien, Susan, Bond, David A., Roeker, Lindsey E., Siddiqi, Tanya, Wang, Michael L., Sun, Clare, Abdel-Wahab, Omar, Schwab, Amanda, Tan, May, Meredith, Erin, Gessner, Melissa A., Kim, Su Young, Wiestner, Adrian, Danilov, Alexey V

Get full text

Prospective evaluation of a breast-cancer risk model integrating classical risk factors and polygenic risk in 15 cohorts from six countries by Hurson, Amber N, Pal Choudhury, Parichoy, Gao, Chi, Hüsing, Anika, Eriksson, Mikael, Shi, Min, Jones, Michael E, Evans, D Gareth R, Milne, Roger L, Gaudet, Mia M, Vachon, Celine M, Chasman, Daniel I, Easton, Douglas F, Schmidt, Marjanka K, Kraft, Peter, Garcia-Closas, Montserrat, Chatterjee, Nilanjan

Get full text

Prospective evaluation of a breast-cancer risk model integrating classical risk factors and polygenic risk in 15 cohorts from six countries by Hurson, Amber N, Pal Choudhury, Parichoy, Gao, Chi, Hüsing, Anika, Eriksson, Mikael, Shi, Min, Jones, Michael E, Evans, D Gareth R, Milne, Roger L, Gaudet, Mia M, Vachon, Celine M, Chasman, Daniel I, Easton, Douglas F, Schmidt, Marjanka K, Kraft, Peter, Garcia-Closas, Montserrat, Chatterjee, Nilanjan

Get full text

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma by Went, Molly, Sud, Amit, Försti, Asta, Halvarsson, Britt-Marie, Weinhold, Niels, Kimber, Scott, van Duin, Mark, Thorleifsson, Gudmar, Holroyd, Amy, Johnson, David C., Li, Ni, Orlando, Giulia, Law, Philip J., Ali, Mina, Chen, Bowang, Mitchell, Jonathan S., Gudbjartsson, Daniel F., Kuiper, Rowan, Stephens, Owen W., Bertsch, Uta, Broderick, Peter, Campo, Chiara, Bandapalli, Obul R, Einsele, Hermann, Gregory, Walter A., Gullberg, Urban, Hillengass, Jens, Hoffmann, Per, Jackson, Graham H., Jöckel, Karl-Heinz, Johnsson, Ellinor, Kristinsson, Sigurður Y., Mellqvist, Ulf-Henrik, Nahi, Hareth, Easton, Douglas, Pharoah, Paul, Dunning, Alison, Peto, Julian, Canzian, Federico, Swerdlow, Anthony, Eeles, Rosalind A., Kote-Jarai, ZSofia, Muir, Kenneth, Pashayan, Nora, Nickel, Jolanta, Nöthen, Markus M., Rafnar, Thorunn, Ross, Fiona M., da Silva Filho, Miguel Inacio, Thomsen, Hauke, Turesson, Ingemar, Vangsted, Annette, Andersen, Niels Frost, Waage, Anders, Walker, Brian A., Wihlborg, Anna-Karin, Broyl, Annemiek, Davies, Faith E., Thorsteinsdottir, Unnur, Langer, Christian, Hansson, Markus, Goldschmidt, Hartmut, Kaiser, Martin, Sonneveld, Pieter, Stefansson, Kari, Morgan, Gareth J., Hemminki, Kari, Nilsson, Björn, Houlston, Richard S.

Get full text

Parent and healthcare provider views of live varicella vaccination of pediatric solid organ transplant recipients by Condran, Brian, Kervin, Melissa, Burton, Catherine, Blydt‐Hansen, Tom D, Morris, Shaun K., Sadarangani, Manish, Otley, Anthony, Yong, Elaine, Mitchell, Hana, Bettinger, Julie A., Top, Karina A., Gilmour, Susan, Ng, Vicky, Teoh, Chia Wei, Piché‐Renaud, Pierre‐Philippe, Pham‐Huy, Anne, Tapiéro, Bruce, Gantt, Soren, Tee, James, Severini, Alberto

Get full text

Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis by Yarmolinsky, James, Bouras, Emmanouil, Constantinescu, Andrei, Burrows, Kimberley, Bull, Caroline J., Vincent, Emma E., Martin, Richard M., Dimopoulou, Olympia, Lewis, Sarah J., Moreno, Victor, Vujkovic, Marijana, Chang, Kyong-Mi, Voight, Benjamin F., Tsao, Philip S., Gunter, Marc J., Hampe, Jochen, Pellatt, Andrew J., Pharoah, Paul D. P., Schoen, Robert E., Gallinger, Steven, Jenkins, Mark A., Pai, Rish K., Gill, Dipender, Tsilidis, Kostas K.

Get full text

Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study by Morales Berstein, Fernanda, McCartney, Daniel L, Lu, Ake T, Tsilidis, Konstantinos K, Bouras, Emmanouil, Haycock, Philip, Burrows, Kimberley, Phipps, Amanda I, Buchanan, Daniel D, Cheng, Iona, Martin, Richard M, Davey Smith, George, Relton, Caroline L, Horvath, Steve, Marioni, Riccardo E, Richardson, Tom G, Richmond, Rebecca C

Get full text

Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo by Ikram, M Kamran, Sim, Xueling, Xueling, Sim, Jensen, Richard A, Cotch, Mary Frances, Hewitt, Alex W, Ikram, M Arfan, Wang, Jie Jin, Klein, Ronald, Klein, Barbara E K, Breteler, Monique M B, Cheung, Ning, Liew, Gerald, Mitchell, Paul, Uitterlinden, Andre G, Rivadeneira, Fernando, Hofman, Albert, de Jong, Paulus T V M, van Duijn, Cornelia M, Kao, Linda, Cheng, Ching-Yu, Smith, Albert Vernon, Glazer, Nicole L, Lumley, Thomas, McKnight, Barbara, Psaty, Bruce M, Jonasson, Fridbert, Eiriksdottir, Gudny, Aspelund, Thor, Harris, Tamara B, Launer, Lenore J, Taylor, Kent D, Li, Xiaohui, Iyengar, Sudha K, Xi, Quansheng, Sivakumaran, Theru A, Mackey, David A, Macgregor, Stuart, Martin, Nicholas G, Young, Terri L, Bis, Josh C, Wiggins, Kerri L, Heckbert, Susan R, Hammond, Christopher J, Andrew, Toby, Fahy, Samantha, Attia, John, Holliday, Elizabeth G, Scott, Rodney J, Islam, F M Amirul, Rotter, Jerome I, McAuley, Annie K, Boerwinkle, Eric, Tai, E Shyong, Gudnason, Vilmundur, Siscovick, David S, Vingerling, Johannes R, Wong, Tien Y

Get full text

Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis by Wormser, David, Angelantonio, Emanuele Di, Kaptoge, Stephen, Wood, Angela M, Gao, Pei, Sun, Qi, Walldius, Göran, Selmer, Randi, Verschuren, WM Monique, Bueno-de-Mesquita, H Bas, Engström, Gunnar, Ridker, Paul M, Njølstad, Inger, Iso, Hiroyasu, Holme, Ingar, Giampaoli, Simona, Tunstall-Pedoe, Hugh, Gaziano, J Michael, Brunner, Eric, Kee, Frank, Tosetto, Alberto, Meisinger, Christa, Brenner, Hermann, Ducimetiere, Pierre, Whincup, Peter H, Tipping, Robert W, Ford, Ian, Cremer, Peter, Hofman, Albert, Wilhelmsen, Lars, Clarke, Robert, Boer, Ian H de, Jukema, J Wouter, Ibañez, Alejandro Marín, Lawlor, Debbie A, D'Agostino, Ralph B, Rodriguez, Beatriz, Casiglia, Edoardo, Stehouwer, Coen DA, Simons, Leon A, Nietert, Paul J, Barrett-Connor, Elizabeth, Panagiotakos, Demosthenes B, Björkelund, Cecilia, Strandberg, Timo E, Wassertheil-Smoller, Sylvia, Blazer, Dan G, Meade, Tom W, Welin, Lennart, Svärdsudd, Kurt, Woodward, Mark, Nissinen, Aulikki, Kromhout, Daan, Jørgensen, Torben, Tilvis, Reijo S, Guralnik, Jack M, Rosengren, Annika, Taylor, James O, Kiechl, Stefan, Dagenais, Gilles R, Gerry, F, Fowkes, R, Wallace, Robert B, Khaw, Kay-Tee, Shaffer, Jonathan A, Visser, Marjolein, Kauhanen, Jussi, Salonen, Jukka T, Gallacher, John, Ben-Shlomo, Yoav, Kitamura, Akihiko, Sundström, Johan, Wennberg, Patrik, Kiyohara, Yutaka, Daimon, Makoto, de la Cámara, Agustin Gómez, Cooper, Jackie A, Onat, Altan, Devereux, Richard, Mukamal, Kenneth J, Dankner, Rachel, Knuiman, Matthew W, Crespo, Carlos J, Gansevoort, Ron T, Goldbourt, Uri, Nordestgaard, Børge G, Shaw, Jonathan E, Mussolino, Michael, Nakagawa, Hidaeki, Fletcher, Astrid, Kuller, Lewis H, Gillum, Richard F, Gudnason, Vilmundur, Assmann, Gerd, Wald, Nicholas, Jousilahti, Pekka R, Greenland, Philip, Trevisan, Maurizio, Ulmer, Hanno, Butterworth, Adam S

Get full text