Search Results - Tennakoon, Mithila

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  1. 1
    Molecular basis of sequence‐dependent differential prenylation inhibition and statin sensitivity of G proteins

    Molecular basis of sequence‐dependent differential prenylation inhibition and statin sensitivity of G proteins by Tennakoon, Mithila I., Karunarathne, Ajith

    Published in The FASEB journal
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  2. 2
    The spatial distribution of GPCR and Gβγ activity across a cell dictates PIP3 dynamics

    The spatial distribution of GPCR and Gβγ activity across a cell dictates PIP3 dynamics by Wijayaratna, Dhanushan, Ratnayake, Kasun, Ubeysinghe, Sithurandi, Kankanamge, Dinesh, Tennakoon, Mithila, Karunarathne, Ajith

    Published in Scientific reports
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  3. 3
    G protein gamma subunit, a hidden master regulator of GPCR signaling

    G protein gamma subunit, a hidden master regulator of GPCR signaling by Kankanamge, Dinesh, Tennakoon, Mithila, Karunarathne, Ajith, Gautam, N.

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  4. 4
    Dissociation of the G protein βγ from the Gq–PLCβ complex partially attenuates PIP2 hydrolysis

    Dissociation of the G protein βγ from the Gq–PLCβ complex partially attenuates PIP2 hydrolysis by Kankanamge, Dinesh, Ubeysinghe, Sithurandi, Tennakoon, Mithila, Pantula, Priyanka Devi, Mitra, Kishalay, Giri, Lopamudra, Karunarathne, Ajith

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  5. 5
    CaaX-motif-adjacent residues influence G protein gamma (Gγ) prenylation under suboptimal conditions

    CaaX-motif-adjacent residues influence G protein gamma (Gγ) prenylation under suboptimal conditions by Tennakoon, Mithila, Thotamune, Waruna, Payton, John L., Karunarathne, Ajith

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  6. 6
    Gγ identity dictates efficacy of Gβγ signaling and macrophage migration

    Gγ identity dictates efficacy of Gβγ signaling and macrophage migration by Senarath, Kanishka, Payton, John L., Kankanamge, Dinesh, Siripurapu, Praneeth, Tennakoon, Mithila, Karunarathne, Ajith

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  7. 7
    A short C-terminal peptide in Gγ regulates Gβγ signaling efficacy

    A short C-terminal peptide in Gγ regulates Gβγ signaling efficacy by Tennakoon, Mithila, Senarath, Kanishka, Kankanamge, Dinesh, Chadee, Deborah N, Karunarathne, Ajith

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  8. 8
    Statins Perturb Gβγ Signaling and Cell Behavior in a Gγ Subtype Dependent Manner

    Statins Perturb Gβγ Signaling and Cell Behavior in a Gγ Subtype Dependent Manner by Tennakoon, Mithila, Kankanamge, Dinesh, Senarath, Kanishka, Fasih, Zehra, Karunarathne, Ajith

    Published in Molecular pharmacology
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  9. 9
    Subtype-dependent regulation of Gβγ signalling

    Subtype-dependent regulation of Gβγ signalling by Tennakoon, Mithila, Senarath, Kanishka, Kankanamge, Dinesh, Ratnayake, Kasun, Wijayaratna, Dhanushan, Olupothage, Koshala, Ubeysinghe, Sithurandi, Martins-Cannavino, Kimberly, Hébert, Terence E., Karunarathne, Ajith

    Published in Cellular signalling
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  10. 10
    Optical approaches for single-cell and subcellular analysis of GPCR–G protein signaling

    Optical approaches for single-cell and subcellular analysis of GPCR–G protein signaling by Kankanamge, Dinesh, Ratnayake, Kasun, Senarath, Kanishka, Tennakoon, Mithila, Harmon, Elise, Karunarathne, Ajith

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  11. 11
    A RAD18–UBC13–PALB2–RNF168 axis mediates replication fork recovery in BRCA1-deficient cancer cells

    A RAD18–UBC13–PALB2–RNF168 axis mediates replication fork recovery in BRCA1-deficient cancer cells by Cybulla, Emily, Wallace, Sierra, Meroni, Alice, Jackson, Jessica, Agashe, Sumedha, Tennakoon, Mithila, Limbu, Mangsi, Quinet, Annabel, Lomonosova, Elena, Noia, Hollie, Tirman, Stephanie, Wood, Matthew, Lemacon, Delphine, Fuh, Katherine, Zou, Lee, Vindigni, Alessandro

    Published in Nucleic acids research
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  12. 12
    G protein αq exerts expression level-dependent distinct signaling paradigms

    G protein αq exerts expression level-dependent distinct signaling paradigms by Kankanamge, Dinesh, Tennakoon, Mithila, Weerasinghe, Amila, Cedeno-Rosario, Luis, Chadee, Deborah N., Karunarathne, Ajith

    Published in Cellular signalling
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