A Facile Method for Oxidation of Primary Alcohols to Carboxylic Acids and Its Application in Glycosaminoglycan Syntheses by Huang, Lijun, Teumelsan, Nardos, Huang, Xuefei

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Synthesis of Branched Man5 Oligosaccharides and an Unusual Stereochemical Observation by Teumelsan, Nardos, Huang, Xuefei

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Discovery of Selective Small Molecule ROMK Inhibitors as Potential New Mechanism Diuretics by Tang, Haifeng, Walsh, Shawn P, Yan, Yan, de Jesus, Reynalda K, Shahripour, Aurash, Teumelsan, Nardos, Zhu, Yuping, Ha, Sookhee, Owens, Karen A, Thomas-Fowlkes, Brande S, Felix, John P, Liu, Jessica, Kohler, Martin, Priest, Birgit T, Bailey, Timothy, Brochu, Richard, Alonso-Galicia, Magdalena, Kaczorowski, Gregory J, Roy, Sophie, Yang, Lihu, Mills, Sander G, Garcia, Maria L, Pasternak, Alexander

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The design and synthesis of novel spirocyclic heterocyclic sulfone ROMK inhibitors as diuretics by Chobanian, Harry R., Guo, Yan, Pio, Barbara, Tang, Haifeng, Teumelsan, Nardos, Clements, Matthew, Frie, Jessica, Ferguson, Ronald, Guo, Zach, Thomas-Fowlkes, Brande S., Felix, John P., Liu, Jessica, Kohler, Martin, Priest, Birgit, Hampton, Caryn, Pai, Lee-Yuh, Corona, Aaron, Metzger, Joseph, Tong, Vincent, Joshi, Elizabeth M., Xu, Ling, Owens, Karen, Maloney, Kevin, Sullivan, Kathleen, Pasternak, Alexander

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Discovery of a potent and selective ROMK inhibitor with improved pharmacokinetic properties based on an octahydropyrazino[2,1-c][1,4]oxazine scaffold by Zhu, Yuping, de Jesus, Reynalda K., Tang, Haifeng, Walsh, Shawn P., Jiang, Jinlong, Gu, Xin, Teumelsan, Nardos, Shahripour, Aurash, Pio, Barbara, Ding, Fa-Xiang, Ha, Sookhee, Priest, Birgit T., Swensen, Andrew M., Alonso-Galicia, Magdalena, Felix, John P., Brochu, Richard M., Bailey, Timothy, Thomas-Fowlkes, Brande, Zhou, Xiaoyan, Pai, Lee-Yuh, Hampton, Caryn, Hernandez, Melba, Owens, Karen, Ehrhart, Juliann, Roy, Sophie, Kaczorowski, Gregory J., Yang, Lihu, Parmee, Emma R., Sullivan, Kathleen, Garcia, Maria L., Pasternak, Alexander

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Differentiation of ROMK potency from hERG potency in the phenacetyl piperazine series through heterocycle incorporation by Walsh, Shawn P., Shahripour, Aurash, Tang, Haifeng, de Jesus, Reynalda K., Teumelsan, Nardos, Zhu, Yuping, Frie, Jessica, Priest, Birgit T., Swensen, Andrew M., Alonso-Galicia, Magdalena, Felix, John P., Brochu, Richard M., Bailey, Timothy, Thomas-Fowlkes, Brande, Zhou, Xiaoyan, Pai, Lee-Yuh, Hampton, Caryn, Hernandez, Melba, Owens, Karen, Ehrhart, Juliann, Roy, Sophie, Kaczorowski, Gregory J., Yang, Lihu, Garcia, Maria L., Pasternak, Alexander

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Discovery of MK-7145, an Oral Small Molecule ROMK Inhibitor for the Treatment of Hypertension and Heart Failure by Tang, Haifeng, Zhu, Yuping, Teumelsan, Nardos, Walsh, Shawn P, Shahripour, Aurash, Priest, Birgit T, Swensen, Andrew M, Felix, John P, Brochu, Richard M, Bailey, Timothy, Thomas-Fowlkes, Brande, Pai, Lee-Yuh, Hampton, Caryn, Corona, Aaron, Hernandez, Melba, Metzger, Joseph, Forrest, Michael, Zhou, Xiaoyan, Owens, Karen, Tong, Vincent, Parmee, Emma, Roy, Sophie, Kaczorowski, Gregory J, Yang, Lihu, Alonso-Galicia, Magdalena, Garcia, Maria L, Pasternak, Alexander

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Discovery of a Potent and Selective ROMK Inhibitor with Pharmacokinetic Properties Suitable for Preclinical Evaluation by Walsh, Shawn P, Shahripour, Aurash, Tang, Haifeng, Teumelsan, Nardos, Frie, Jessica, Zhu, Yuping, Priest, Birgit T, Swensen, Andrew M, Liu, Jessica, Margulis, Michael, Visconti, Richard, Weinglass, Adam, Felix, John P, Brochu, Richard M, Bailey, Timothy, Thomas-Fowlkes, Brande, Alonso-Galicia, Magdalena, Zhou, Xiaoyan, Pai, Lee-Yuh, Corona, Aaron, Hampton, Caryn, Hernandez, Melba, Bentley, Ross, Chen, Jing, Shah, Kashmira, Metzger, Joseph, Forrest, Michael, Owens, Karen, Tong, Vincent, Ha, Sookhee, Roy, Sophie, Kaczorowski, Gregory J, Yang, Lihu, Parmee, Emma, Garcia, Maria L, Sullivan, Kathleen, Pasternak, Alexander

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