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Preclinical characterization of MTX-101: a novel bispecific CD8 Treg modulator that restores CD8 Treg functions to suppress pathogenic T cells in autoimmune diseases
by
Gardell, Jennifer L
,
Maurer, Meghan E
,
Childs, Monica M
,
Pham, Minh N
,
Meengs, Brent
,
Julien, Susan H
,
Tan, Cong
,
Boster, Daniel R
,
Quach, Phoenicia
,
Therriault, Jon H
,
Hermansky, Gleda
,
Patton, Daniel T
,
Bowser, Justin
,
Chen, Alex
,
Morgan, Nadine N
,
Gilbertson, Emily A
,
Bogatzki, Lisa
,
Encarnacion, Kaelen
,
McMahan, Catherine J
,
Crane, Courtney A
,
Swiderek, Kristine M
Published in
Frontiers in immunology
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A NEWLY DISCOVERED REGULATORY CD8 T CELL NETWORK HAS THE POTENTIAL TO REGULATE AND ELIMINATE PATHOGENIC CD4 T CELLS IN AUTOIMMUNE MEDIATED DISEASE OF THE GUT
by
Crane, Courtney
,
Bowser, Justin
,
Fasnacht, Rachael
,
Gardell, Jennifer
,
Maurer, Meghan
,
Julien, Susan
,
Templeton, Megan
,
Therriault, Jon Henry
,
Swiderek, Kristine
Published in
Inflammatory bowel diseases
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Bispecific CD8 Treg modulators regulate a novel regulatory CD8 T cell network and eliminate pathogenic CD4 T cells in live cell co-culture system
by
Gardell, Jennifer L
,
Crane, Courtney
,
Bowser, Justin
,
Fasnacht, Rachael
,
Julien, Susan
,
Maurer, Meghan E
,
Templeton, Megan
,
Therriault, Jon
,
Yang, Su Jung
,
Swiderek, Kristine M
Published in
The Journal of immunology (1950)
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Demonstration of regulatory CD8 T cell prevalence, phenotype, and functions in autoimmune patients treated with a tolerizing peptide vaccine
by
Maurer, Meghan
,
Bowser, Justin
,
Fasnacht, Rachael
,
Gardell, Jennifer L
,
Julien, Susan
,
Templeton, Megan
,
Therriault, Jon
,
Yang, Su J
,
Swiderek, Kristine
,
Crane, Courtney
Published in
The Journal of immunology (1950)
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A KIR x CD8 targeting bispecific modulator enhances regulatory CD8 T cell functions, and reduces inflammation in models of autoimmune disease
by
Gardell, Jennifer L
,
Boster, Daniel
,
Bowser, Justin
,
Fasnacht, Rachael
,
Fitzpatrick, Kristin
,
Hermansky, Gleda
,
Julien, Susan
,
Maurer, Meghan
,
McMahan, Catherine
,
Meengs, Brent
,
Patton, Daniel
,
Pham, Minh
,
Therriault, Jon
,
Swiderek, Kristine M
,
Crane, Courtney
Published in
The Journal of immunology (1950)
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Impact of depth filtration on disulfide bond reduction during downstream processing of monoclonal antibodies from CHO cell cultures
by
O’Mara, Brian
,
Gao, Zhong‐Hua
,
Kuruganti, Manju
,
Mallett, Robert
,
Nayar, Gautam
,
Smith, Laura
,
Meyer, Jeffrey D.
,
Therriault, Jon
,
Miller, Cameron
,
Cisney, John
,
Fann, John
Published in
Biotechnology and bioengineering
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Pre-clinical pharmacologic and tolerability characterization of a novel KIRxCD8 targeting bispecific CD8 Treg modulator
by
McMahan, Catherine J
,
Pham, Minh
,
Boster, Daniel
,
Hermansky, Gleda
,
Gardell, Jennifer
,
Bowser, Justin
,
Rachael, Fasnacht
,
Chen, Alex
,
Gilbertson, Emily
,
Morgan, Nadine
,
Childs, Monica
,
Fitzpatrick, Kristin
,
Tan, Cong
,
Mauer, Meghan
,
Meengs, Brent
,
Therriault, Jon
,
Patton, Dan
,
Julien, Susan
,
Crane, Courtney
,
Swiderek, Kristine M
Published in
The Journal of immunology (1950)
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The Journal Of Immunology
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Biotechnology And Bioengineering
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Frontiers In Immunology
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Antibodies, Bispecific - Pharmacology
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Autoimmune Disease Affected Tissue Organoids
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Cd8 Regulatory T Cells
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