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EGF‐like and Other Disulfide‐rich Microdomains as Therapeutic Scaffolds
by
Tombling, Benjamin J.
,
Wang, Conan K.
,
Craik, David J.
Published in
Angewandte Chemie International Edition
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The emerging landscape of peptide-based inhibitors of PCSK9
by
Tombling, Benjamin J.
,
Zhang, Yuhui
,
Huang, Yen-Hua
,
Craik, David J.
,
Wang, Conan K.
Published in
Atherosclerosis
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Improving Stability Enhances In Vivo Efficacy of a PCSK9 Inhibitory Peptide
by
Zhang, Yuhui
,
Wang, Li
,
Tombling, Benjamin J.
,
Lammi, Carmen
,
Huang, Yen-Hua
,
Li, Yue
,
Bartolomei, Martina
,
Hong, Bin
,
Craik, David J.
,
Wang, Conan K.
Published in
Journal of the American Chemical Society
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Bioactive Cyclization Optimizes the Affinity of a Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Peptide Inhibitor
by
Tombling, Benjamin J
,
Lammi, Carmen
,
Lawrence, Nicole
,
Gilding, Edward K
,
Grazioso, Giovanni
,
Craik, David J
,
Wang, Conan K
Published in
Journal of medicinal chemistry
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Increased Valency Improves Inhibitory Activity of Peptides Targeting Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)
by
Tombling, Benjamin J.
,
Lammi, Carmen
,
Bollati, Carlotta
,
Anoldi, Anna
,
Craik, David J.
,
Wang, Conan K.
Published in
Chembiochem : a European journal of chemical biology
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Cystine-knot peptide inhibitors of HTRA1 bind to a cryptic pocket within the active site region
by
Li, Yanjie
,
Wei, Yuehua
,
Ultsch, Mark
,
Li, Wei
,
Tang, Wanjian
,
Tombling, Benjamin
,
Gao, Xinxin
,
Dimitrova, Yoana
,
Gampe, Christian
,
Fuhrmann, Jakob
,
Zhang, Yingnan
,
Hannoush, Rami N.
,
Kirchhofer, Daniel
Published in
Nature communications
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In Planta Discovery and Chemical Synthesis of Bracelet Cystine Knot Peptides from Rinorea bengalensis
by
Dang, Tien T
,
Chan, Lai Y
,
Tombling, Benjamin J
,
Harvey, Peta J
,
Gilding, Edward K
,
Craik, David J
Published in
Journal of natural products (Washington, D.C.)
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The acyclotide ribe 31 from Rinorea bengalensis has selective cytotoxicity and potent insecticidal properties in Drosophila
by
Dang, Tien T.
,
Huang, Yen-Hua
,
Ott, Stanislav
,
Harvey, Peta J.
,
Gilding, Edward K.
,
Tombling, Benjamin J.
,
Chan, Lai Y.
,
Kaas, Quentin
,
Claridge-Chang, Adam
,
Craik, David J.
Published in
The Journal of biological chemistry
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Engineered EGF‑A Peptides with Improved Affinity for Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)
by
Tombling, Benjamin J
,
Lammi, Carmen
,
Lawrence, Nicole
,
Li, Jianqiang
,
Arnoldi, Anna
,
Craik, David J
,
Wang, Conan K
Published in
ACS chemical biology
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EGF‐artige und andere disulfidreiche Mikrodomänen als therapeutische Molekülgerüste
by
Tombling, Benjamin J.
,
Wang, Conan K.
,
Craik, David J.
Published in
Angewandte Chemie
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Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffolds
by
Craik, David J.
,
Lee, Meng-Han
,
Rehm, Fabian B.H.
,
Tombling, Benjamin
,
Doffek, Benjamin
,
Peacock, Hayden
Published in
Bioorganic & medicinal chemistry
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EGF‐artige und andere disulfidreiche Mikrodomänen als therapeutische Molekülgerüste
by
Tombling, Benjamin J.
,
Wang, Conan K.
,
Craik, David J.
Published in
Angewandte Chemie
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