Accurate and efficient detection of gene fusions from RNA sequencing data by Uhrig, Sebastian, Ellermann, Julia, Walther, Tatjana, Burkhardt, Pauline, Fröhlich, Martina, Hutter, Barbara, Toprak, Umut H, Neumann, Olaf, Stenzinger, Albrecht, Scholl, Claudia, Fröhling, Stefan, Brors, Benedikt

Get full text

Cyclical Curriculum Learning by Kesgin, H. Toprak, Amasyali, M. Fatih

Get full text

Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations by Jabs, Julia, Zickgraf, Franziska M, Park, Jeongbin, Wagner, Steve, Jiang, Xiaoqi, Jechow, Katharina, Kleinheinz, Kortine, Toprak, Umut H, Schneider, Marc A, Meister, Michael, Spaich, Saskia, Sütterlin, Marc, Schlesner, Matthias, Trumpp, Andreas, Sprick, Martin, Eils, Roland, Conrad, Christian

Get full text

NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer by Heining, Christoph, Horak, Peter, Uhrig, Sebastian, Codo, Paula L, Klink, Barbara, Hutter, Barbara, Fröhlich, Martina, Bonekamp, David, Richter, Daniela, Steiger, Katja, Penzel, Roland, Endris, Volker, Ehrenberg, Karl Roland, Frank, Stephanie, Kleinheinz, Kortine, Toprak, Umut H, Schlesner, Matthias, Mandal, Ranadip, Schulz, Lothar, Lambertz, Helmut, Fetscher, Sebastian, Bitzer, Michael, Malek, Nisar P, Horger, Marius, Giese, Nathalia A, Strobel, Oliver, Hackert, Thilo, Springfeld, Christoph, Feuerbach, Lars, Bergmann, Frank, Schröck, Evelin, von Kalle, Christof, Weichert, Wilko, Scholl, Claudia, Ball, Claudia R, Stenzinger, Albrecht, Brors, Benedikt, Fröhling, Stefan, Glimm, Hanno

Get full text

Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer by Ishaque, Naveed, Abba, Mohammed L., Hauser, Christine, Patil, Nitin, Paramasivam, Nagarajan, Huebschmann, Daniel, Leupold, Jörg Hendrik, Balasubramanian, Gnana Prakash, Kleinheinz, Kortine, Toprak, Umut H., Hutter, Barbara, Benner, Axel, Shavinskaya, Anna, Zhou, Chan, Gu, Zuguang, Kerssemakers, Jules, Marx, Alexander, Moniuszko, Marcin, Kozlowski, Miroslaw, Reszec, Joanna, Niklinski, Jacek, Eils, Jürgen, Schlesner, Matthias, Eils, Roland, Brors, Benedikt, Allgayer, Heike

Get full text

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs by Orr, Brent A., Toprak, Umut H., Hovestadt, Volker, Jones, David T.W., Capper, David, Sill, Martin, Buchhalter, Ivo, Northcott, Paul A., Leis, Irina, Ryzhova, Marina, Koelsche, Christian, Pfaff, Elke, Allen, Sariah J., Balasubramanian, Gnanaprakash, Brabetz, Sebastian, Johann, Pascal D., Sahm, Felix, Mackay, Alan, Remke, Marc, Phillips, Joanna J., Perry, Arie, Cowdrey, Cynthia, Drissi, Rachid, Fouladi, Maryam, Giangaspero, Felice, Grajkowska, Wiesława, Scheurlen, Wolfram, Pietsch, Torsten, Hagel, Christian, Gojo, Johannes, Lötsch, Daniela, Berger, Walter, Slavc, Irene, Haberler, Christine, Jouvet, Anne, Holm, Stefan, Hofer, Silvia, Prinz, Marco, Keohane, Catherine, Fried, Iris, Mawrin, Christian, Scheie, David, Mobley, Bret C., Schniederjan, Matthew J., Santi, Mariarita, Buccoliero, Anna M., Dahiya, Sonika, Kramm, Christof M., von Bueren, André O., von Hoff, Katja, Rutkowski, Stefan, Herold-Mende, Christel, Frühwald, Michael C., Milde, Till, Wesseling, Pieter, Rößler, Jochen, Schüller, Ulrich, Ebinger, Martin, Schittenhelm, Jens, Frank, Stephan, Grobholz, Rainer, Vajtai, Istvan, Hans, Volkmar, Schneppenheim, Reinhard, Zitterbart, Karel, Collins, V. Peter, Aronica, Eleonora, Varlet, Pascale, Puget, Stephanie, Figarella-Branger, Dominique, Wolter, Marietta, Schuhmann, Martin U., Shalaby, Tarek, Grotzer, Michael, van Meter, Timothy, Monoranu, Camelia-Maria, Reifenberger, Guido, Snuderl, Matija, Forrester, Lynn Ann, Koster, Jan, Versteeg, Rogier, Volckmann, Richard, van Sluis, Peter, Wolf, Stephan, Mikkelsen, Tom, Gajjar, Amar, Aldape, Kenneth, Moore, Andrew S., Taylor, Michael D., Jones, Chris, Jabado, Nada, Karajannis, Matthias A., Eils, Roland, Schlesner, Matthias, Lichter, Peter, von Deimling, Andreas, Pfister, Stefan M., Ellison, David W., Korshunov, Andrey, Kool, Marcel

Get full text

Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome by Hartlieb, Sabine A., Sieverling, Lina, Nadler-Holly, Michal, Ziehm, Matthias, Toprak, Umut H., Herrmann, Carl, Ishaque, Naveed, Okonechnikov, Konstantin, Gartlgruber, Moritz, Park, Young-Gyu, Wecht, Elisa Maria, Savelyeva, Larissa, Henrich, Kai-Oliver, Rosswog, Carolina, Fischer, Matthias, Hero, Barbara, Jones, David T. W., Pfaff, Elke, Witt, Olaf, Pfister, Stefan M., Volckmann, Richard, Koster, Jan, Kiesel, Katharina, Rippe, Karsten, Taschner-Mandl, Sabine, Ambros, Peter, Brors, Benedikt, Selbach, Matthias, Feuerbach, Lars, Westermann, Frank

Get full text

Mutational patterns and regulatory networks in epigenetic subgroups of meningioma by Paramasivam, Nagarajan, Hübschmann, Daniel, Toprak, Umut H, Ishaque, Naveed, Neidert, Marian, Schrimpf, Daniel, Stichel, Damian, Reuss, David, Sievers, Philipp, Reinhardt, Annekathrin, Wefers, Annika K., Jones, David T. W., Gu, Zuguang, Werner, Johannes, Uhrig, Sebastian, Wirsching, Hans-Georg, Schick, Matthias, Bewerunge-Hudler, Melanie, Beck, Katja, Brehmer, Stephanie, Urbschat, Steffi, Seiz-Rosenhagen, Marcel, Hänggi, Daniel, Herold-Mende, Christel, Ketter, Ralf, Eils, Roland, Ram, Zvi, Pfister, Stefan M., Wick, Wolfgang, Weller, Michael, Grossmann, Rachel, von Deimling, Andreas, Schlesner, Matthias, Sahm, Felix

Get full text

MYC/MIZ1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation by Shostak, Anton, Ruppert, Bianca, Ha, Nati, Bruns, Philipp, Toprak, Umut H., Eils, Roland, Schlesner, Matthias, Diernfellner, Axel, Brunner, Michael

Get full text

Association of trochlear dysplasia with knee meniscal–cartilage damage and anterior cruciate ligament mucoid degeneration by Atay, M., Yılmaz, T.F., Sarı, L., Toprak, H.

Get full text

Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone by Lutsik, Pavlo, Baude, Annika, Mancarella, Daniela, Öz, Simin, Kühn, Alexander, Toth, Reka, Hey, Joschka, Toprak, Umut H., Lim, Jinyeong, Nguyen, Viet Ha, Jiang, Chao, Mayakonda, Anand, Hartmann, Mark, Rosemann, Felix, Breuer, Kersten, Vonficht, Dominik, Grünschläger, Florian, Lee, Suman, Schuhmacher, Maren Kirstin, Kusevic, Denis, Jauch, Anna, Weichenhan, Dieter, Zustin, Jozef, Schlesner, Matthias, Haas, Simon, Park, Joo Hyun, Park, Yoon Jung, Oppermann, Udo, Jeltsch, Albert, Haller, Florian, Fellenberg, Jörg, Lindroth, Anders M., Plass, Christoph

Get full text

Cryptic insertion of MYC exons 2 and 3 into the immunoglobulin heavy chain locus detected by whole genome sequencing in a case of " MYC -negative" Burkitt lymphoma by Wagener, Rabea, Bens, Susanne, Toprak, Umut H, Seufert, Julian, López, Cristina, Scholz, Ingrid, Herbrueggen, Heidi, Oschlies, Ilske, Stilgenbauer, Stephan, Schlesner, Matthias, Klapper, Wolfram, Burkhardt, Birgit, Siebert, Reiner

Get full text

Comprehensive genomic analysis of refractory multiple myeloma reveals a complex mutational landscape associated with drug resistance and novel therapeutic vulnerabilities by Giesen, Nicola, Paramasivam, Nagarajan, Toprak, Umut H, Huebschmann, Daniel, Xu, Jing, Uhrig, Sebastian, Samur, Mehmet, Bähr, Stella, Fröhlich, Martina, Mughal, Sadaf S, Mai, Elias K, Jauch, Anna, Müller-Tidow, Carsten, Brors, Benedikt, Munshi, Nikhil, Goldschmidt, Hartmut, Weinhold, Niels, Schlesner, Matthias, Raab, Marc S

Get full text

Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas by Lopez, Cristina, Schleussner, Nikolai, Bernhart, Stephan H, Kleinheinz, Kortine, Sungalee, Stephanie, Sczakiel, Henrike L, Kretzmer, Helene, Toprak, Umut H, Glaser, Selina, Wagener, Rabea, Ammerpohl, Ole, Bens, Susanne, Giefing, Maciej, Sanchez, Juan C Gonzalez, Apic, Gordana, Hubschmann, Daniel, Janz, Martin, Kreuz, Markus, Mottok, Anja, Muller, Judith M, Seufert, Julian, Hoffmann, Steve, Korbel, Jan O, Russell, Robert B, Schule, Roland, Trumper, Lorenz, Klapper, Wolfram, Radlwimmer, Bernhard, Lichter, Peter, Kuppers, Ralf, Schlesner, Matthias, Mathas, Stephan, Siebert, Reiner

Get full text

Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma by George, Sally L, Lorenzi, Federica, King, David, Hartlieb, Sabine, Campbell, James, Pemberton, Helen, Toprak, Umut H, Barker, Karen, Tall, Jennifer, da Costa, Barbara Martins, van den Boogaard, Marlinde L, Dolman, M Emmy M, Molenaar, Jan J, Bryant, Helen E, Westermann, Frank, Lord, Christopher J, Chesler, Louis

Get full text

Modulation of the Chromatin Phosphoproteome by the Haspin Protein Kinase by Maiolica, Alessio, de Medina-Redondo, Maria, Schoof, Erwin M., Chaikuad, Apirat, Villa, Fabrizio, Gatti, Marco, Jeganathan, Siva, Lou, Hua Jane, Novy, Karel, Hauri, Simon, Toprak, Umut H., Herzog, Franz, Meraldi, Patrick, Penengo, Lorenza, Turk, Benjamin E., Knapp, Stefan, Linding, Rune, Aebersold, Ruedi

Get full text

Chiari Type 1 malformation: CSF flow dynamics and morphology in the posterior fossa and craniocervical junction and correlation of these findings with syrinx formation by Yilmaz, T.F., Toprak, H., Sari, L., Oz, I.I., Kitis, S., Kaya, A., Alkan, A.

Get full text

Conserved Peptide Fragmentation as a Benchmarking Tool for Mass Spectrometers and a Discriminating Feature for Targeted Proteomics by Toprak, Umut H., Gillet, Ludovic C., Maiolica, Alessio, Navarro, Pedro, Leitner, Alexander, Aebersold, Ruedi

Get full text

Multidetector CT findings in gastrointestinal tract perforation that can help prediction of perforation site accurately by Toprak, H., Yilmaz, T.F., Yurtsever, İ., Sharifov, R., Gültekin, M.A., Yiğman, S., Yildiz, Ş.

Get full text

Abstract 2696: Four new brain tumor entities emerge from molecular classification of CNS-PNETs by Sturm, Dominik, Orr, Brent, Toprak, Umut H., Hovestadt, Volker, Jones, David T.W., Capper, David, Lichter, Peter, Korshunov, Andrey, Pfister, Stefan M., Ellison, David W., Kool, Marcel

Get full text