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Discovery of 2‑(Cyclopentylamino)thieno[3,2‑d]pyrimidin-4(3H)‑one Derivatives as a New Series of Potent Phosphodiesterase 7 Inhibitors
by
Kawai, Kentaro
,
Endo, Yusuke
,
Asano, Takeshi
,
Amano, Seiji
,
Sawada, Keisuke
,
Ueo, Noriko
,
Takahashi, Nobuaki
,
Sonoda, Yo
,
Nagai, Mika
,
Kamei, Noriyuki
,
Nagata, Naoya
Published in
Journal of medicinal chemistry
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2-(Isopropylamino)thieno[3,2-d]pyrimidin-4(3H)-one derivatives as selective phosphodiesterase 7 inhibitors with potent in vivo efficacy
by
Endo, Yusuke
,
Kawai, Kentaro
,
Asano, Takeshi
,
Amano, Seiji
,
Asanuma, Yoshihito
,
Sawada, Keisuke
,
Onodera, Yuuta
,
Ueo, Noriko
,
Takahashi, Nobuaki
,
Sonoda, Yo
,
Kamei, Noriyuki
,
Irie, Tetsumi
Published in
Bioorganic & medicinal chemistry letters
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Discovery and SAR study of 2-(4-pyridylamino)thieno[3,2-d]pyrimidin-4(3H)-ones as soluble and highly potent PDE7 inhibitors
by
Endo, Yusuke
,
Kawai, Kentaro
,
Asano, Takeshi
,
Amano, Seiji
,
Asanuma, Yoshihito
,
Sawada, Keisuke
,
Ogura, Keiji
,
Nagata, Naoya
,
Ueo, Noriko
,
Takahashi, Nobuaki
,
Sonoda, Yo
,
Kamei, Noriyuki
Published in
Bioorganic & medicinal chemistry letters
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Expression levels of renal organic anion transporters (OATs) and their correlation with anionic drug excretion in patients with renal diseases
by
Sakurai, Yuji
,
Motohashi, Hideyuki
,
Ueo, Harumasa
,
Masuda, Satohiro
,
Saito, Hideyuki
,
Okuda, Masahiro
,
Mori, Noriko
,
Matsuura, Motokazu
,
Doi, Toshio
,
Fukatsu, Atsushi
,
Ogawa, Osamu
,
Inui, Ken-ichi
Published in
Pharmaceutical research
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Bioorganic & Medicinal Chemistry Letters
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Journal Of Medicinal Chemistry
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Pharmaceutical Research
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Subjects
Life Sciences & Biomedicine
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Pharmacology & Pharmacy
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Science & Technology
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Chemistry
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Chemistry, Medicinal
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Cyclic Nucleotide Phosphodiesterases, Type 7 - Antagonists & Inhibitors
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Physical Sciences
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Structure-Activity Relationship
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Animals
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Aqueous Solubility
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Chemistry, Organic
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Cyclic Nucleotide Phosphodiesterases, Type 7 - Metabolism
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Dose-Response Relationship, Drug
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Humans
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Male
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Mice
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Phosphodiesterase
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Phosphodiesterase Inhibitors - Chemical Synthesis
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Pyrimidinones - Chemical Synthesis
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Pyrimidinones - Pharmacology
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Sciencedirect Journals
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Sciencedirect Freedom Collection
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Backfile Package - Organic Chemistry (Legacy) [Yco]
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American Chemical Society
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American Chemical Society:jisc Collections:american Chemical Society Read & Publish Agreement 2022-2024 (Reading List)
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Springer Nature
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American Chemical Society (Acs) Open Access
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Springer Link Archives
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Springerlink Contemporary
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