Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors by Wegert, Jenny, Ishaque, Naveed, Vardapour, Romina, Geörg, Christina, Gu, Zuguang, Bieg, Matthias, Ziegler, Barbara, Bausenwein, Sabrina, Nourkami, Nasenien, Ludwig, Nicole, Keller, Andreas, Grimm, Clemens, Kneitz, Susanne, Williams, Richard D., Chagtai, Tas, Pritchard-Jones, Kathy, van Sluis, Peter, Volckmann, Richard, Koster, Jan, Versteeg, Rogier, Acha, Tomas, O’Sullivan, Maureen J., Bode, Peter K., Niggli, Felix, Tytgat, Godelieve A., van Tinteren, Harm, van den Heuvel-Eibrink, Marry M., Meese, Eckart, Vokuhl, Christian, Leuschner, Ivo, Graf, Norbert, Eils, Roland, Pfister, Stefan M., Kool, Marcel, Gessler, Manfred

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The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers by Muñoz, Javier, Stange, Daniel E, Schepers, Arnout G, van de Wetering, Marc, Koo, Bon-Kyoung, Itzkovitz, Shalev, Volckmann, Richard, Kung, Kevin S, Koster, Jan, Radulescu, Sorina, Myant, Kevin, Versteeg, Rogier, Sansom, Owen J, van Es, Johan H, Barker, Nick, van Oudenaarden, Alexander, Mohammed, Shabaz, Heck, Albert J R, Clevers, Hans

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A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma by van Groningen, Tim, Akogul, Nurdan, Westerhout, Ellen M., Chan, Alvin, Hasselt, Nancy E., Zwijnenburg, Danny A., Broekmans, Marloes, Stroeken, Peter, Haneveld, Franciska, Hooijer, Gerrit K. J., Savci-Heijink, C. Dilara, Lakeman, Arjan, Volckmann, Richard, van Sluis, Peter, Valentijn, Linda J., Koster, Jan, Versteeg, Rogier, van Nes, Johan

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Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome by Hartlieb, Sabine A., Sieverling, Lina, Nadler-Holly, Michal, Ziehm, Matthias, Toprak, Umut H., Herrmann, Carl, Ishaque, Naveed, Okonechnikov, Konstantin, Gartlgruber, Moritz, Park, Young-Gyu, Wecht, Elisa Maria, Savelyeva, Larissa, Henrich, Kai-Oliver, Rosswog, Carolina, Fischer, Matthias, Hero, Barbara, Jones, David T. W., Pfaff, Elke, Witt, Olaf, Pfister, Stefan M., Volckmann, Richard, Koster, Jan, Kiesel, Katharina, Rippe, Karsten, Taschner-Mandl, Sabine, Ambros, Peter, Brors, Benedikt, Selbach, Matthias, Feuerbach, Lars, Westermann, Frank

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Transcriptomic Differences Underlying the Activin-A Induced Large Osteoclast Formation in Both Healthy Control and Fibrodysplasia Ossificans Progressiva Osteoclasts by Schoenmaker, Ton, Zwaak, Joy, Loos, Bruno G, Volckmann, Richard, Koster, Jan, Eekhoff, E Marelise W, de Vries, Teun J

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The pluripotency factor NANOG contributes to mesenchymal plasticity and is predictive for outcome in esophageal adenocarcinoma by van der Zalm, Amber P., Dings, Mark P. G., Manoukian, Paul, Boersma, Hannah, Janssen, Reimer, Bailey, Peter, Koster, Jan, Zwijnenburg, Danny, Volckmann, Richard, Bootsma, Sanne, Waasdorp, Cynthia, van Mourik, Monique, Blangé, Dionne, van den Ende, Tom, Oyarce, César I., Derks, Sarah, Creemers, Aafke, Ebbing, Eva A., Hooijer, Gerrit K., Meijer, Sybren L., van Berge Henegouwen, Mark I., Medema, Jan Paul, van Laarhoven, Hanneke W. M., Bijlsma, Maarten F.

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The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta–Notch pathway in neuroblastoma by Revet, Ingrid, Huizenga, Gerda, Chan, Alvin, Koster, Jan, Volckmann, Richard, van Sluis, Peter, Øra, Ingrid, Versteeg, Rogier, Geerts, Dirk

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Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma by Koppen, Arjen, Ait-Aissa, Rachida, Koster, Jan, van Sluis, Peter G, Øra, Ingrid, Caron, Huib N, Volckmann, Richard, Versteeg, Rogier, Valentijn, Linda J

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Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups by Pajtler, Kristian W., Witt, Hendrik, Sill, Martin, Jones, David T.W., Hovestadt, Volker, Kratochwil, Fabian, Wani, Khalida, Tatevossian, Ruth, Punchihewa, Chandanamali, Johann, Pascal, Reimand, Jüri, Warnatz, Hans-Jörg, Ryzhova, Marina, Mack, Steve, Ramaswamy, Vijay, Capper, David, Schweizer, Leonille, Sieber, Laura, Wittmann, Andrea, Huang, Zhiqin, van Sluis, Peter, Volckmann, Richard, Koster, Jan, Versteeg, Rogier, Fults, Daniel, Toledano, Helen, Avigad, Smadar, Hoffman, Lindsey M., Donson, Andrew M., Foreman, Nicholas, Hewer, Ekkehard, Zitterbart, Karel, Gilbert, Mark, Armstrong, Terri S., Gupta, Nalin, Allen, Jeffrey C., Karajannis, Matthias A., Zagzag, David, Hasselblatt, Martin, Kulozik, Andreas E., Witt, Olaf, Collins, V. Peter, von Hoff, Katja, Rutkowski, Stefan, Pietsch, Torsten, Bader, Gary, Yaspo, Marie-Laure, von Deimling, Andreas, Lichter, Peter, Taylor, Michael D., Gilbertson, Richard, Ellison, David W., Aldape, Kenneth, Korshunov, Andrey, Kool, Marcel, Pfister, Stefan M.

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Abstract 2490: R2: Genomics analysis and visualization platform by Koster, Jan, Volckmann, Richard, Zwijnenburg, Danny, Molenaar, Piet, Versteeg, Rogier

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Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes by Johann, Pascal D., Erkek, Serap, Zapatka, Marc, Kerl, Kornelius, Buchhalter, Ivo, Hovestadt, Volker, Jones, David T.W., Sturm, Dominik, Hermann, Carl, Segura Wang, Maia, Korshunov, Andrey, Rhyzova, Marina, Gröbner, Susanne, Brabetz, Sebastian, Chavez, Lukas, Bens, Susanne, Gröschel, Stefan, Kratochwil, Fabian, Wittmann, Andrea, Sieber, Laura, Geörg, Christina, Wolf, Stefan, Beck, Katja, Oyen, Florian, Capper, David, van Sluis, Peter, Volckmann, Richard, Koster, Jan, Versteeg, Rogier, von Deimling, Andreas, Milde, Till, Witt, Olaf, Kulozik, Andreas E., Ebinger, Martin, Shalaby, Tarek, Grotzer, Michael, Sumerauer, David, Zamecnik, Josef, Mora, Jaume, Jabado, Nada, Taylor, Michael D., Huang, Annie, Aronica, Eleonora, Bertoni, Anna, Radlwimmer, Bernhard, Pietsch, Torsten, Schüller, Ulrich, Schneppenheim, Reinhard, Northcott, Paul A., Korbel, Jan O., Siebert, Reiner, Frühwald, Michael C., Lichter, Peter, Eils, Roland, Gajjar, Amar, Hasselblatt, Martin, Pfister, Stefan M., Kool, Marcel

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Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma by Northcott, Paul A., Lee, Catherine, Zichner, Thomas, Stütz, Adrian M., Erkek, Serap, Kawauchi, Daisuke, Shih, David J. H., Hovestadt, Volker, Zapatka, Marc, Sturm, Dominik, Jones, David T. W., Kool, Marcel, Remke, Marc, Cavalli, Florence M. G., Zuyderduyn, Scott, Bader, Gary D., VandenBerg, Scott, Esparza, Lourdes Adriana, Ryzhova, Marina, Wang, Wei, Wittmann, Andrea, Stark, Sebastian, Sieber, Laura, Seker-Cin, Huriye, Linke, Linda, Kratochwil, Fabian, Jäger, Natalie, Buchhalter, Ivo, Imbusch, Charles D., Zipprich, Gideon, Raeder, Benjamin, Schmidt, Sabine, Diessl, Nicolle, Wolf, Stephan, Wiemann, Stefan, Brors, Benedikt, Lawerenz, Chris, Eils, Jürgen, Warnatz, Hans-Jörg, Risch, Thomas, Yaspo, Marie-Laure, Weber, Ursula D., Bartholomae, Cynthia C., von Kalle, Christof, Turányi, Eszter, Hauser, Peter, Sanden, Emma, Darabi, Anna, Siesjö, Peter, Sterba, Jaroslav, Zitterbart, Karel, Sumerauer, David, van Sluis, Peter, Versteeg, Rogier, Volckmann, Richard, Koster, Jan, Schuhmann, Martin U., Ebinger, Martin, Grimes, H. Leighton, Robinson, Giles W., Gajjar, Amar, Mynarek, Martin, von Hoff, Katja, Rutkowski, Stefan, Pietsch, Torsten, Scheurlen, Wolfram, Felsberg, Jörg, Reifenberger, Guido, Kulozik, Andreas E., von Deimling, Andreas, Witt, Olaf, Eils, Roland, Gilbertson, Richard J., Korshunov, Andrey, Taylor, Michael D., Lichter, Peter, Korbel, Jan O., Wechsler-Reya, Robert J., Pfister, Stefan M.

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Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma by Sturm, Dominik, Witt, Hendrik, Hovestadt, Volker, Khuong-Quang, Dong-Anh, Jones, David T.W., Konermann, Carolin, Pfaff, Elke, Tönjes, Martje, Sill, Martin, Bender, Sebastian, Kool, Marcel, Zapatka, Marc, Becker, Natalia, Zucknick, Manuela, Hielscher, Thomas, Liu, Xiao-Yang, Fontebasso, Adam M., Ryzhova, Marina, Albrecht, Steffen, Jacob, Karine, Wolter, Marietta, Ebinger, Martin, Schuhmann, Martin U., van Meter, Timothy, Frühwald, Michael C., Hauch, Holger, Pekrun, Arnulf, Radlwimmer, Bernhard, Niehues, Tim, von Komorowski, Gregor, Dürken, Matthias, Kulozik, Andreas E., Madden, Jenny, Donson, Andrew, Foreman, Nicholas K., Drissi, Rachid, Fouladi, Maryam, Scheurlen, Wolfram, von Deimling, Andreas, Monoranu, Camelia, Roggendorf, Wolfgang, Herold-Mende, Christel, Unterberg, Andreas, Kramm, Christof M., Felsberg, Jörg, Hartmann, Christian, Wiestler, Benedikt, Wick, Wolfgang, Milde, Till, Witt, Olaf, Lindroth, Anders M., Schwartzentruber, Jeremy, Faury, Damien, Fleming, Adam, Zakrzewska, Magdalena, Liberski, Pawel P., Zakrzewski, Krzysztof, Hauser, Peter, Garami, Miklos, Klekner, Almos, Bognar, Laszlo, Morrissy, Sorana, Cavalli, Florence, Taylor, Michael D., van Sluis, Peter, Koster, Jan, Versteeg, Rogier, Volckmann, Richard, Mikkelsen, Tom, Aldape, Kenneth, Reifenberger, Guido, Collins, V. Peter, Majewski, Jacek, Korshunov, Andrey, Lichter, Peter, Plass, Christoph, Jabado, Nada, Pfister, Stefan M.

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Dissecting the genomic complexity underlying medulloblastoma by Jones, David T. W., Jäger, Natalie, Kool, Marcel, Zichner, Thomas, Hutter, Barbara, Sultan, Marc, Cho, Yoon-Jae, Pugh, Trevor J., Hovestadt, Volker, Stütz, Adrian M., Rausch, Tobias, Warnatz, Hans-Jörg, Ryzhova, Marina, Bender, Sebastian, Sturm, Dominik, Pleier, Sabrina, Cin, Huriye, Pfaff, Elke, Sieber, Laura, Wittmann, Andrea, Remke, Marc, Witt, Hendrik, Hutter, Sonja, Tzaridis, Theophilos, Weischenfeldt, Joachim, Raeder, Benjamin, Avci, Meryem, Amstislavskiy, Vyacheslav, Zapatka, Marc, Weber, Ursula D., Wang, Qi, Lasitschka, Bärbel, Bartholomae, Cynthia C., Schmidt, Manfred, von Kalle, Christof, Ast, Volker, Lawerenz, Chris, Eils, Jürgen, Kabbe, Rolf, Benes, Vladimir, van Sluis, Peter, Koster, Jan, Volckmann, Richard, Shih, David, Betts, Matthew J., Russell, Robert B., Coco, Simona, Paolo Tonini, Gian, Schüller, Ulrich, Hans, Volkmar, Graf, Norbert, Kim, Yoo-Jin, Monoranu, Camelia, Roggendorf, Wolfgang, Unterberg, Andreas, Herold-Mende, Christel, Milde, Till, Kulozik, Andreas E., von Deimling, Andreas, Witt, Olaf, Maass, Eberhard, Rössler, Jochen, Ebinger, Martin, Schuhmann, Martin U., Frühwald, Michael C., Hasselblatt, Martin, Jabado, Nada, Rutkowski, Stefan, von Bueren, André O., Williamson, Dan, Clifford, Steven C., McCabe, Martin G., Peter Collins, V., Wolf, Stephan, Wiemann, Stefan, Lehrach, Hans, Brors, Benedikt, Scheurlen, Wolfram, Felsberg, Jörg, Reifenberger, Guido, Northcott, Paul A., Taylor, Michael D., Meyerson, Matthew, Pomeroy, Scott L., Yaspo, Marie-Laure, Korbel, Jan O., Korshunov, Andrey, Eils, Roland, Pfister, Stefan M., Lichter, Peter

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Fibroblast activation protein identifies Consensus Molecular Subtype 4 in colorectal cancer and allows its detection by 68Ga-FAPI-PET imaging by Strating, Esther, Wassenaar, Emma, Verhagen, Mathijs, Rauwerdink, Paulien, van Schelven, Susanne, de Hingh, Ignace, Rinkes, Inne Borel, Boerma, Djamila, Witkamp, Arjen, Lacle, Miangela, Fodde, Riccardo, Volckmann, Richard, Koster, Jan, Stedingk, Kris, Giesel, Frederik, de Roos, Remmert, Poot, Alex, Bol, Guus, Lam, Marnix, Elias, Sjoerd, Kranenburg, Onno

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Mesenchymal-Type Neuroblastoma Cells Escape ALK Inhibitors by Westerhout, Ellen M, Hamdi, Mohamed, Stroeken, Peter, Nowakowska, Natalia E, Lakeman, Arjan, van Arkel, Jennemiek, Hasselt, Nancy E, Bleijlevens, Boris, Akogul, Nurdan, Haneveld, Franciska, Chan, Alvin, van Sluis, Peter, Zwijnenburg, Danny, Volckmann, Richard, van Noesel, Carel J M, Adameyko, Igor, van Groningen, Tim, Koster, Jan, Valentijn, Linda J, van Nes, Johan, Versteeg, Rogier

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RAS-MAPK pathway-driven tumor progression is associated with loss of CIC and other genomic aberrations in neuroblastoma by Eleveld, Thomas F, Schild, Linda, Koster, Jan, Zwijnenburg, Danny A, Alles, Lindy K, Ebus, Marli E, Volckmann, Richard, Tytgat, Godelieve A M, van Sluis, Peter, Versteeg, Rogier, Molenaar, Jan J

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Peritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacity by Laoukili, Jamila, Constantinides, Alexander, Wassenaar, Emma C. E., Elias, Sjoerd G., Raats, Danielle A. E., van Schelven, Susanne J., van Wettum, Jonathan, Volckmann, Richard, Koster, Jan, Huitema, Alwin D. R., Nienhuijs, Simon W., de Hingh, Ignace H. J. T., Wiezer, René J., van Grevenstein, Helma M. U., Rinkes, Inne H. M. Borel, Boerma, Djamila, Kranenburg, Onno

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Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation by Orth, Martin F., Surdez, Didier, Faehling, Tobias, Ehlers, Anna C., Marchetto, Aruna, Grossetête, Sandrine, Volckmann, Richard, Zwijnenburg, Danny A., Gerke, Julia S., Zaidi, Sakina, Alonso, Javier, Sastre, Ana, Baulande, Sylvain, Sill, Martin, Cidre-Aranaz, Florencia, Ohmura, Shunya, Kirchner, Thomas, Hauck, Stefanie M., Reischl, Eva, Gymrek, Melissa, Pfister, Stefan M., Strauch, Konstantin, Koster, Jan, Delattre, Olivier, Grünewald, Thomas G.P.

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Correction: Mesenchymal-Type Neuroblastoma Cells Escape ALK Inhibitors by Westerhout, Ellen M., Hamdi, Mohamed, Stroeken, Peter, Nowakowska, Natalia E., Lakeman, Arjan, van Arkel, Jennemiek, Hasselt, Nancy E., Blejlevens, Boris, Akogul, Nurdan, Haneveld, Franciska, Chan, Alvin, van Sluis, Peter, Zwijnenburg, Danny, Volckmann, Richard, van Noesel, Carel JM, Adameyko, Igor, van Gronigen, Tim, Koster, Jan, Valentijn, Linda J., van Nes, Johan, Versteeg, Rogier

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