P11.82.A TARGETING THE GLIOBLASTOMA MASTER REGULATOR C/EBPß: A PHARMACOKINETIC AND PHARMACODYNAMIC NEOADJUVANT STUDY OF ST101 by Iwamoto, F, Al Dalahmah, O, Manjrekar, K, Levrero, C, Michel, R, Bargo, A, Kaesshaefer, S, Butowski, N, Peters, K, Buerki, R, Bexon, A, Vainstein-Haras, A

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BL‐8040 CXCR4 antagonist is safe and demonstrates antileukemic activity in combination with cytarabine for the treatment of relapsed/refractory acute myelogenous leukemia: An open‐... by Borthakur, Gautam, Ofran, Yishai, Tallman, Martin S., Foran, James, Uy, Geoffrey L., DiPersio, John F., Showel, Margaret M., Shimoni, Avichai, Nagler, Arnon, Rowe, Jacob M., Altman, Jessica K., Abraham, Michal, Peled, Amnon, Shaw, Stephen, Bohana‐Kashtan, Osnat, Sorani, Ella, Pereg, Yaron, Foley‐Comer, Adam, Oberkovitz, Galia, Lustig, Tzipi M., Glicko‐Kabir, Irit, Aharon, Arnon, Vainstein‐Haras, Abi, Kadosh, Shaul E., Samara, Emil, Al‐Rawi, Ahmed N., Pemmaraju, Naveen, Bueso‐Ramos, Carlos, Cortes, Jorge E., Andreeff, Michael

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Motixafortide and Pembrolizumab Combined to Nanoliposomal Irinotecan, Fluorouracil, and Folinic Acid in Metastatic Pancreatic Cancer: The COMBAT/KEYNOTE-202 Trial by Bockorny, Bruno, Macarulla, Teresa, Semenisty, Valerya, Borazanci, Erkut, Feliu, Jaime, Ponz-Sarvise, Mariano, Abad, David Gutierrez, Oberstein, Paul, Alistar, Angela, Muñoz, Andres, Geva, Ravit, Guillén-Ponce, Carmen, Fernandez, Mercedes Salgado, Peled, Amnon, Chaney, Marya, Gliko-Kabir, Irit, Shemesh-Darvish, Liron, Ickowicz, Debby, Sorani, Ella, Kadosh, Shaul, Vainstein-Haras, Abi, Hidalgo, Manuel

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CTNI-44. NEOADJUVANT TREATMENT WITH ST101, C/EBPΒ ANTAGONIST, TRIGGERS NECROSIS AS A PATHOLOGICAL RESPONSE IN NEWLY DIAGNOSED GBM PATIENTS. TISSUE-BASED ANALYSIS FROM A SURGICAL WI... by Iwamoto, Fabio, Vainstein-Haras, Abi, Rotolo, Jim, Levrero, Clara, Michel, Robert, Kostelecky, Nicolas, Papaioannou, Anastasia, Buerki, Robin

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Abstract CT177: A multi-center phase 2a trial of the CXCR4 inhibitor motixafortide (BL-8040) (M) in combination with pembrolizumab (P) and chemotherapy (C), in patients with metast... by Hidalgo, Manuel, Macarulla, Teresa, Semenisty, Valerya, Borazanci, Erkut, Feliu, Jaime, Ponz-Sarvise, Mariano, Abad, David Gutierrez, Oberstein, Paul, Alistar, Angela, Muñoz, Andres, Geva, Ravit, Guillén-Ponce, Carmen, Fernandez, Mercedes Salgado, Peled, Amnon, Chaney, Marya, Glicko-Kabir, Irit, Shemesh-Darvish, Liron, Ickowicz, Debby, Sorani, Ella, Kadosh, Shaul E., Vainstein-Haras, Abi, Bockorny, Bruno

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Abstract CT204: High cytotoxic T-cell or polymorphonuclear cell infiltrates in the tumor microenvironment correlate with responses to BL8040 plus pembrolizumab combination therapy... by Barreto, Carmelia M. Noia, Ledesma, Debora A., Gite, Swati, Solis, Luisa M., Jiang, Mei, Pandurengan, Renganayaki K., Wolff, Robert, Javle, Milind, Pant, Shubham, Varadhachary, Gauri, Shroff, Rachna, Vainstein-Haras, Abi, Sorani, Ella, Lustig, Tzipora M., Kashtan, Osnat, Gozlan, Yosi, Townson, Steven M., Fahey, Jeanne M., Yao, James, Wistuba, Ignacio I., Overman, Michael, Fogelman, David, Parra, Edwin R.

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Abstract B038: Clinical and biological activity of ST101, a peptide antagonist of C/EBPβ, in recurrent Glioblastoma (rGBM) patients. Results from the rGBM cohort of a multi-cohort... by Iwamoto, Fabio, Buerki, Robin, Butowski, Nicholas, Peters, Katherine B., Williams, Anja, Falchook, Gerald, Rotolo, Jim, Michel, Rob, Kaesshaefer, Stephen, Scuoppo, Claudio, Vainstein-Haras, Abi

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Abstract LB016: Immunotherapeutic potential of ST316, a peptide antagonist of β-catenin by Scuoppo, Claudio, Ghamsari, Lila, Gallagher, Erin, Leong, Siok, Koester, Mark, Ramirez, Rick, Gonzales, Jerel, Merutka, Gene, Kappel, Barry, Vainstein-Haras, Abi, Rotolo, Jim

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Abstract LB236: ST101, a peptide antagonist of novel I/O target CEBPβ,reprograms MDSCs and promotes an immunoactive tumor microenvironment by Scuoppo, Claudio, Ramirez, Rick, Leong, Siok, Ghamsari, Lila, Capiaux, Gina, Michel, Rob, Kaesshaefer, Steve, Merutka, Gene, Kappel, Barry, Vainstein-Haras, Abi, Bexon, Alice, Rotolo, Jim

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Hematopoietic stem cell mobilization for allogeneic stem cell transplantation by motixafortide, a novel CXCR4 inhibitor by Crees, Zachary D., Rettig, Michael P., Bashey, Asad, Devine, Steven M., Jaglowski, Samantha, Wan, Fei, Zhou, Amy, Harding, Melinda, Vainstein-Haras, Abi, Sorani, Ella, Gliko-Kabir, Irit, Grossman, Brenda J., Westervelt, Peter, DiPersio, John F., Uy, Geoffrey L.

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Motixafortide Enables Consistent, Robust Hematopoietic Stem Cell Collection (HSC) across Populations with Increased Impaired HSC Mobilization: A Sub-Group Analysis of the Genesis S... by Crees, Zachary D, Rettig, Michael P., Jayasinghe, Reyka, Stockerl-Goldstein, Keith, Larson, Sarah M, Arpad, Illes, Milone, Giuseppe, Martino, Massimo, Stiff, Patrick J., Sborov, Douglas, Pereira, Denise, Micallef, Ivana N, Moreno-Jiménez, Gemma, Mikala, Gabor, Coronel, Maria L Paciello, Holtick, Udo, Hiemenz, John, Qazilbash, Muzaffar H., Hardy, Dr. Nancy Maureen, Latif, Tahir, Garcia-Cadenas, Irene, Vainstein-Haras, Abi, Sorani, Ella, Gliko-Kabir, Irit, Goldstein, Inbal, Ickowicz, Debby, Darvish, Liron, Kadosh, Shaul, Gao, Feng, Schroeder, Mark A., Vij, Ravi, DiPersio, John F.

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