The potent BACE1 inhibitor LY2886721 elicits robust central Aβ pharmacodynamic responses in mice, dogs, and humans by May, Patrick C, Willis, Brian A, Lowe, Stephen L, Dean, Robert A, Monk, Scott A, Cocke, Patrick J, Audia, James E, Boggs, Leonard N, Borders, Anthony R, Brier, Richard A, Calligaro, David O, Day, Theresa A, Ereshefsky, Larry, Erickson, Jon A, Gevorkyan, Hykop, Gonzales, Celedon R, James, Douglas E, Jhee, Stanford S, Komjathy, Steven F, Li, Linglin, Lindstrom, Terry D, Mathes, Brian M, Martényi, Ferenc, Sheehan, Scott M, Stout, Stephanie L, Timm, David E, Vaught, Grant M, Watson, Brian M, Winneroski, Leonard L, Yang, Zhixiang, Mergott, Dustin J

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Defining Target Engagement Required for Efficacy In Vivo at the Retinoic Acid Receptor-Related Orphan Receptor C2 (RORγt) by Lugar, Charles W, Clarke, Christian A, Morphy, Richard, Rudyk, Helene, Sapmaz, Selma, Stites, Ryan E, Vaught, Grant M, Furness, Kelly, Broughton, Howard B, Durst, Greg L, Clawson, David K, Stout, Stephanie L, Guo, Sherry Y, Durbin, Jim D, Stayrook, Keith R, Edmondson, Denise D, Kikly, Kristy, New, Nicole E, Bina, Holly A, Chambers, Mark G, Shetler, Pamela, Chang, William Y, Chang, Veavi Ching-Yun, Barr, Rob, Gough, Wendy H, Steele, Jimmy P, Getman, Brian, Patel, Nita, Mathes, Brian M, Richardson, Timothy I

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2‑Chloro-4-[[(1R,2R)‑2-hydroxy-2-methyl-cyclopentyl]amino]-3-methyl-benzonitrile: A Transdermal Selective Androgen Receptor Modulator (SARM) for Muscle Atrophy by Saeed, Ashraf, Vaught, Grant M, Gavardinas, Kostas, Matthews, Donald, Green, Jonathan E, Losada, Pablo Garcia, Bullock, Heather A, Calvert, Nathan A, Patel, Nita J, Sweetana, Stephanie A, Krishnan, Venkatesh, Henck, Judith W, Luz, John G, Wang, Yong, Jadhav, Prabhakar

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A novel class of AMPA receptor allosteric modulators. Part 1: Design, synthesis, and SAR of 3-aryl-4-cyano-5-substituted-heteroaryl-2-carboxylic acid derivatives by Fernandez, Maria-Carmen, Castaño, Ana, Dominguez, Esteban, Escribano, Ana, Jiang, Delu, Jimenez, Alma, Hong, Eric, Hornback, William J., Nisenbaum, Eric S., Rankl, Nancy, Tromiczak, Eric, Vaught, Grant, Zarrinmayeh, Hamideh, Zimmerman, Dennis M.

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Neuropeptide Y (NPY): Genetic Variation in the Human Promoter Alters Glucocorticoid Signaling, Yielding Increased NPY Secretion and Stress Responses by KUIXING ZHANG, FANGWEN RAO, STRIDSBERG, Mats, KHANDRIKA, Srikrishna, BISWAS, Nilima, FUNG, Maple M, WAALEN, Jill, MIDDELBERG, Rita P, HEATH, Andrew C, MONTGOMERY, Grant W, MARTIN, Nicholas G, WHITFIELD, John B, PABLO MIRAMONTES-GONZALEZ, Jose, BAKER, Dewleen G, SCHORK, Nicholas J, NIEVERGELT, Caroline M, O'CONNOR, Daniel T, MAKENA HIGHTOWER, C, VAUGHT, Brian, YUHONG CHEN, GREENWOOD, Tiffany A, SCHORK, Andrew J, LEI WANG, MAHATA, Manjula

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Neuropeptide Y (NPY) by Zhang, Kuixing, MD, PhD, Rao, Fangwen, MD, Pablo Miramontes-Gonzalez, Jose, MD, PhD, Hightower, C. Makena, PhD, Vaught, Brian, BS, Chen, Yuhong, MD, Greenwood, Tiffany A., PhD, Schork, Andrew J., BS, Wang, Lei, PhD, Mahata, Manjula, PhD, Stridsberg, Mats, PhD, Khandrika, Srikrishna, PhD, Biswas, Nilima, PhD, Fung, Maple M., MD, Waalen, Jill, MD, MPH, Middelberg, Rita P., PhD, Heath, Andrew C., PhD, Montgomery, Grant W., PhD, Martin, Nicholas G., PhD, Whitfield, John B., PhD, Baker, Dewleen G., MD, Schork, Nicholas J., PhD, Nievergelt, Caroline M., PhD, O'Connor, Daniel T., MD

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Enhancing Programming Error Messages in Real Time with Generative AI by Kimmel, Bailey, Geisert, Austin, Yaro, Lily, Gipson, Brendan, Hotchkiss, Taylor, Osae-Asante, Sidney, Vaught, Hunter, Wininger, Grant, Yamaguchi, Chase

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