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In vitro and in silico analysis of the effects of D2 receptor antagonist target binding kinetics on the cellular response to fluctuating dopamine concentrations
by
Witte, Wilhelmus E A
,
Versfelt, Joost W
,
Kuzikov, Maria
,
Rolland, Solene
,
Georgi, Victoria
,
Gribbon, Philip
,
Gul, Sheraz
,
Huntjens, Dymphy
,
Graaf, Piet Hein
,
Danhof, Meindert
,
Fernández‐Montalván, Amaury
,
Witt, Gesa
,
Lange, Elizabeth C M
Published in
British journal of pharmacology
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In vitro and in silico analysis of the effects of D 2 receptor antagonist target binding kinetics on the cellular response to fluctuating dopamine concentrations
by
de Witte, Wilhelmus E A
,
Versfelt, Joost W
,
Kuzikov, Maria
,
Rolland, Solene
,
Georgi, Victoria
,
Gribbon, Philip
,
Gul, Sheraz
,
Huntjens, Dymphy
,
van der Graaf, Piet Hein
,
Danhof, Meindert
,
Fernández-Montalván, Amaury
,
Witt, Gesa
,
de Lange, Elizabeth C M
Published in
British journal of pharmacology
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British Journal Of Pharmacology
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Subjects
Kinetics
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Animals
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Binding Sites - Drug Effects
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Cho Cells
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Computer Simulation
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Cricetulus
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Cyclic Amp
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Dopamine
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Dopamine - Pharmacology
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Dopamine Antagonists - Pharmacology
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Dopamine D2 Receptors
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Feedback
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Fluctuations
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Life Sciences & Biomedicine
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Models, Biological
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Negative Feedback
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Pharmacodynamics
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Pharmacokinetics
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Pharmacology & Pharmacy
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Receptors, Dopamine D2 - Metabolism
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