Abstract 3402: In vivo efficacy of RAF/MEK clamp avutometinib (VS-6766) in combination with FAK inhibition in low grade serous ovarian cancer by McNamara, Blair, Demirkiran, Cem, Bellone, Stefania, Mutlu, Levent, Zipponi, Margherita, Verzosa, Miguel S., Harold, Justin, Hartwich, Tobias M., Altwerger, Gary, Ratner, Elena, Huang, Gloria, Clark, Mitchell, Andikyan, Vaagn, Azodi, Masoud, Schwartz, Peter E., Dottino, Peter, Santin, Alessandro D.

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The Poly (ADP-ribose) polymerase inhibitor olaparib and pan-ErbB inhibitor neratinib are highly synergistic in HER2 overexpressing epithelial ovarian carcinoma in vitro and in vivo by Han, Chanhee, McNamara, Blair, Bellone, Stefania, Harold, Justin, Manara, Paola, Hartwich, Tobias Max Philipp, Mutlu, Levent, Yang-Hartwich, Yang, Zipponi, Margherita, Demirkiran, Cem, Verzosa, Miguel Skyler Z., Altwerger, Gary, Ratner, Elena, Huang, Gloria S., Clark, Mitchell, Andikyan, Vaagn, Azodi, Masoud, Dottino, Peter R., Schwartz, Peter E., Santin, Alessandro D.

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Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody–drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma w... by Mauricio, Dennis, Bellone, Stefania, Mutlu, Levent, McNamara, Blair, Manavella, Diego D., Demirkiran, Cem, Verzosa, Miguel Skyler Z., Buza, Natalia, Hui, Pei, Hartwich, Tobias Max Philipp, Harold, Justin, Yang-Hartwich, Yang, Zipponi, Margherita, Altwerger, Gary, Ratner, Elena, Huang, Gloria S., Clark, Mitchell, Andikyan, Vaagn, Azodi, Masoud, Schwartz, Peter E., Santin, Alessandro D.

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Elimusertib (BAY1895344), a novel ATR inhibitor, demonstrates in vivo activity in ATRX mutated models of uterine leiomyosarcoma by Harold, Justin, Bellone, Stefania, Manavella, Diego D., Mutlu, Levent, McNamara, Blair, Hartwich, Tobias Max Philipp, Zipponi, Margherita, Yang-Hartwich, Yang, Demirkiran, Cem, Verzosa, Miguel Skyler, Choi, Jungmin, Dong, Weilai, Buza, Natalia, Hui, Pei, Altwerger, Gary, Huang, Gloria S., Andikyan, Vaagn, Clark, Mitchell, Ratner, Elena, Azodi, Masoud, Schwartz, Peter E., Santin, Alessandro D.

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Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody–drug conjugate, demonstrates in vitro and in vivo antitumor activity against primary and metastatic ovarian tumors over... by Mutlu, Levent, McNamara, Blair, Bellone, Stefania, Manavella, Diego D., Demirkiran, Cem, Greenman, Michelle, Verzosa, Miguel Skyler Z., Buza, Natalia, Hui, Pei, Hartwich, Tobias Max Philipp, Harold, Justin, Yang-Hartwich, Yang, Zipponi, Margherita, Altwerger, Gary, Ratner, Elena, Huang, Gloria S., Clark, Mitchell, Andikyan, Vaagn, Azodi, Masoud, Schwartz, Peter E., Santin, Alessandro D.

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Uterine leiomyosarcomas harboring MAP2K4 gene amplification are sensitive in vivo to PLX8725, a novel MAP2K4 inhibitor by McNamara, Blair, Harold, Justin, Manavella, Diego, Bellone, Stefania, Mutlu, Levent, Hartwich, Tobias Max Philipp, Zipponi, Margherita, Yang-Hartwich, Yang, Demirkiran, Cem, Verzosa, Miguel Skyler Z., Yang, Kevin, Choi, Jungmin, Dong, Weilai, Buza, Natalia, Hui, Pei, Altwerger, Gary, Huang, Gloria S., Andikyan, Vaagn, Clark, Mitchell, Ratner, Elena, Azodi, Masoud, Schwartz, Peter E., Burton, Elizabeth A., Inagaki, Hiroaki, Albers, Aaron, Zhang, Chao, Bollag, Gideon, Schlessinger, Joseph, Santin, Alessandro D.

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In Vivo and In Vitro Efficacy of Trastuzumab Deruxtecan in Uterine Serous Carcinoma by Mutlu, Levent, Manavella, Diego D., Bellone, Stefania, McNamara, Blair, Harold, Justin A., Mauricio, Dennis, Siegel, Eric R., Buza, Natalia, Hui, Pei, Hartwich, Tobias Max Philipp, Yang-Hartwich, Yang, Demirkiran, Cem, Verzosa, Miguel Skyler Z., Altwerger, Gary, Ratner, Elena S., Huang, Gloria S., Clark, Mitchell, Andikyan, Vaagn, Azodi, Masoud, Dottino, Peter R., Schwartz, Peter E., Santin, Alessandro D.

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Corrigendum to “Elimusertib (BAY1895344), a novel ATR inhibitor, demonstrates in vivo activity in ATRX mutated models of uterine leiomyosarcoma” by Harold, Justin, Bellone, Stefania, Manavell, Diego D., Mutlu, Levent, McNamara, Blair, Hartwich, Tobias Max Philipp, Zipponi, Margherita, Yang-Hartwich, Yang, Demirkiran, Cem, Verzosa, Miguel Skyler Z., Choi, Jungmin, Dong, Weilai, Buza, Natalia, Hui, Pei, Altwerger, Gary, Huang, Gloria S., Andikyan, Vaagn, Clark, Mitchell, Ratner, Elena, Azodi, Masoud, Schwartz, Peter E., Santin, Alessandro D.

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Uterine Leiomyosarcomas harboring MAP2K4 gene amplification are markedly sensitive in vivo to PLX8725, a Novel MAP2K4 Inhibitor (1315) by McNamara, Blair, Harold, Justin, Manavella, Diego, Bellone, Stefania, Mutlu, Levent, Hartwich, Tobias, Zipponi, Margherita, Yang-Hartwich, Yang, Demirkiran, Cem, Verzosa, Miguel Skyler, Choi, Jungmin, Dong, Weilai, Buza, Natalia, Hui, Pei, Altwerger, Gary, Huang, Gloria, Andikyan, Vaagn, Clark, Mitchell, Ratner, Elena, Azodi, Masoud, Schwartz, Peter, Schlessinger, Joseph, Santin, Alessandro

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Ovarian and uterine carcinosarcomas are sensitive in vitro and in vivo to elimusertib, a novel ataxia-telangiectasia and Rad3-related (ATR) kinase inhibitor by Manavella, Diego D., McNamara, Blair, Harold, Justin, Bellone, Stefania, Hartwich, Tobias Max Philipp, Yang-Hartwich, Yang, Mutlu, Levent, Zipponi, Margherita, Demirkiran, Cem, Verzosa, Miguel Skyler, Altwerger, Gary, Ratner, Elena, Huang, Gloria S., Clark, Mitchell, Andikyan, Vaagn, Azodi, Masoud, Schwartz, Peter E., Dottino, Peter R., Choi, Jungmin, Alexandrov, Ludmil B., Buza, Natalia, Hui, Pei, Santin, Alessandro D.

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