Search Results - Volpato, Jordan P.

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  1. 1
    Multiple Conformers in Active Site of Human Dihydrofolate Reductase F31R/Q35E Double Mutant Suggest Structural Basis for Methotrexate Resistance

    Multiple Conformers in Active Site of Human Dihydrofolate Reductase F31R/Q35E Double Mutant Suggest Structural Basis for Methotrexate Resistance by Volpato, Jordan P., Yachnin, Brahm J., Blanchet, Jonathan, Guerrero, Vanessa, Poulin, Lucie, Fossati, Elena, Berghuis, Albert M., Pelletier, Joelle N.

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  2. 2
    Increasing Methotrexate Resistance by Combination of Active-site Mutations in Human Dihydrofolate Reductase

    Increasing Methotrexate Resistance by Combination of Active-site Mutations in Human Dihydrofolate Reductase by Volpato, Jordan P., Fossati, Elena, Pelletier, Joelle N.

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  3. 3
    Combinatorial active‐site variants confer sustained clavulanate resistance in BlaC β‐lactamase from Mycobacterium tuberculosis

    Combinatorial active‐site variants confer sustained clavulanate resistance in BlaC β‐lactamase from Mycobacterium tuberculosis by Egesborg, Philippe, Carlettini, Hélène, Volpato, Jordan P., Doucet, Nicolas

    Published in Protein science
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  4. 4
    Asymmetric mutations in the tetrameric R67 dihydrofolate reductase reveal high tolerance to active‐site substitutions

    Asymmetric mutations in the tetrameric R67 dihydrofolate reductase reveal high tolerance to active‐site substitutions by Ebert, Maximilian C. C. J. C., Morley, Krista L., Volpato, Jordan P., Schmitzer, Andreea R., Pelletier, Joelle N.

    Published in Protein science
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  5. 5
    Mutational ‘hot-spots’ in mammalian, bacterial and protozoal dihydrofolate reductases associated with antifolate resistance: Sequence and structural comparison

    Mutational ‘hot-spots’ in mammalian, bacterial and protozoal dihydrofolate reductases associated with antifolate resistance: Sequence and structural comparison by Volpato, Jordan P, Pelletier, Joelle N

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  6. 6
    Selectively weakened binding of methotrexate by human dihydrofolate reductase allows rapid ex vivo selection of mammalian cells

    Selectively weakened binding of methotrexate by human dihydrofolate reductase allows rapid ex vivo selection of mammalian cells by Volpato, Jordan P., Mayotte, Nadine, Fossati, Elena, Guerrero, Vanessa, Sauvageau, Guy, Pelletier, Joelle N.

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  7. 7
    2-Tier Bacterial and In Vitro Selection of Active and Methotrexate-Resistant Variants of Human Dihydrofolate Reductase

    2-Tier Bacterial and In Vitro Selection of Active and Methotrexate-Resistant Variants of Human Dihydrofolate Reductase by Fossati, Elena, Volpato, Jordan P., Poulin, Lucie, Guerrero, Vanessa, Dugas, David-Antoine, Pelletier, Joelle N.

    Published in SLAS discovery
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  8. 8
    Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure

    Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure by Yachnin, Brahm J., Colin, Damien Y., Volpato, Jordan P., Ebert, Maximilian, Pelletier, Joelle N., Berghuis, Albert M.

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  9. 9
    Combinatorial active‐site variants confer sustained clavulanate resistance in B laC β‐lactamase from M ycobacterium tuberculosis

    Combinatorial active‐site variants confer sustained clavulanate resistance in B laC β‐lactamase from M ycobacterium tuberculosis by Egesborg, Philippe, Carlettini, Hélène, Volpato, Jordan P., Doucet, Nicolas

    Published in Protein science
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  10. 10
    Combinatorial active-site variants confer sustained clavulanate resistance in BlaC [beta]-lactamase from Mycobacterium tuberculosis

    Combinatorial active-site variants confer sustained clavulanate resistance in BlaC [beta]-lactamase from Mycobacterium tuberculosis by Egesborg, Philippe, Carlettini, Hélène, Volpato, Jordan P, Doucet, Nicolas

    Published in Protein science
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