Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-Peptidyl Molecules. 1. Discovery and Optimization of Salicylaldehyde Thiosemicarbazone Thrombopoietin Mi... by Duffy, Kevin J, Shaw, Anthony N, Delorme, Evelyne, Dillon, Susan B, Erickson-Miller, Connie, Giampa, Leslie, Huang, Yifang, Keenan, Richard M, Lamb, Peter, Liu, Nannan, Miller, Stephen G, Price, Alan T, Rosen, Jon, Smith, Heather, Wiggall, Kenneth J, Zhang, Lihua, Luengo, Juan I

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3-(1,1-Dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, Potent Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase by Tedesco, Rosanna, Shaw, Antony N, Bambal, Ramesh, Chai, Deping, Concha, Nestor O, Darcy, Michael G, Dhanak, Dashyant, Fitch, Duke M, Gates, Adam, Gerhardt, Warren G, Halegoua, Dina L, Han, Chao, Hofmann, Glenn A, Johnston, Victor K, Kaura, Arun C, Liu, Nannan, Keenan, Richard M, Lin-Goerke, Juili, Sarisky, Robert T, Wiggall, Kenneth J, Zimmerman, Michael N, Duffy, Kevin J

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Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-Peptidyl Molecules. 2. Rational Design of Naphtho[1,2-d]imidazole Thrombopoietin Mimics by Duffy, Kevin J, Price, Alan T, Delorme, Evelyne, Dillon, Susan B, Duquenne, Celine, Erickson-Miller, Connie, Giampa, Leslie, Huang, Yifang, Keenan, Richard M, Lamb, Peter, Liu, Nannan, Miller, Stephen G, Rosen, Jon, Shaw, Anthony N, Smith, Heather, Wiggall, Kenneth J, Zhang, Lihua, Luengo, Juan I

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Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase by Shaw, Antony N., Tedesco, Rosanna, Bambal, Ramesh, Chai, Deping, Concha, Nestor O., Darcy, Michael G., Dhanak, Dashyant, Duffy, Kevin J., Fitch, Duke M., Gates, Adam, Johnston, Victor K., Keenan, Richard M., Lin-Goerke, Juili, Liu, Nannan, Sarisky, Robert T., Wiggall, Kenneth J., Zimmerman, Michael N.

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Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors by Tedesco, Rosanna, Chai, Deping, Darcy, Michael G., Dhanak, Dashyant, Fitch, Duke M., Gates, Adam, Johnston, Victor K., Keenan, Richard M., Lin-Goerke, Juili, Sarisky, Robert T., Shaw, Antony N., Valko, Klara L., Wiggall, Kenneth J., Zimmerman, Michael N., Duffy, Kevin J.

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Hydrazinonaphthalene and Azonaphthalene Thrombopoietin Mimics Are Nonpeptidyl Promoters of Megakaryocytopoiesis by Duffy, Kevin J, Darcy, Michael G, Delorme, Evelyne, Dillon, Susan B, Eppley, Daniel F, Erickson-Miller, Connie, Giampa, Leslie, Hopson, Christopher B, Huang, Yifang, Keenan, Richard M, Lamb, Peter, Leong, Lynnette, Liu, Nannan, Miller, Stephen G, Price, Alan T, Rosen, Jon, Shah, Rakhi, Shaw, Tony N, Smith, Heather, Stark, Kenneth C, Tian, Shin-Shay, Tyree, Curtis, Wiggall, Kenneth J, Zhang, Lily, Luengo, Juan I

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Reversible inhibitors of the gastric (H+/K+)-ATPase. 3. 3-Substituted-4-(phenylamino)quinolines by Ife, Robert J, Brown, Thomas H, Keeling, David J, Leach, Colin A, Meeson, Malcolm L, Parsons, Michael E, Reavill, David R, Theobald, Colin J, Wiggall, Kenneth J

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Reversible inhibitors of the gastric (H+/K+)-ATPase. 2. 1-Arylpyrrolo[3,2-c]quinolines: effect of the 4-substituent by Leach, Colin A, Brown, Thomas H, Ife, Robert J, Keeling, David J, Laing, Shiona M, Parsons, Michael E, Price, Carolyn A, Wiggall, Kenneth J

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Reversible Inhibitors of the Gastric (H+/K+)-ATPase. 4. Identification of an Inhibitor with an Intermediate Duration of Action by Leach, Colin A, Brown, Thomas H, Ife, Robert J, Keeling, David J, Parsons, Michael E, Theobald, Colin J, Wiggall, Kenneth J

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Reversible inhibitors of the gastric (H+/K+)-ATPase. 1. 1-Aryl-4-methylpyrrolo[3,2-c]quinolines as conformationally restrained analogs of 4-(arylamino)quinolines by Brown, Thomas H, Ife, Robert J, Keeling, David J, Laing, Shiona M, Leach, Colin A, Parsons, Michael E, Price, Carolyn A, Reavill, David R, Wiggall, Kenneth J

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Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzo-thiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitor... by TEDESCO, Rosanna, DEPING CHAI, SHAW, Antony N, VALKO, Klara L, WIGGALL, Kenneth J, ZIMMERMAN, Michael N, DUFFY, Kevin J, DARCY, Michael G, DHANAK, Dashyant, FITCH, Duke M, GATES, Adam, JOHNSTON, Victor K, KEENAN, Richard M, LIN-GOERKE, Juili, SARISKY, Robert T

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Discovery of SB-497115, a Small-Molecule Thrombopoietin (TPO) Receptor Agonist for the Treatment of Thrombocytopenia by Luengo, Juan I., Duffy, Kevin J., Shaw, Anthony N., Delorme, Evelyne, Wiggall, Kenneth J., Giampa, Leslie, Liu, Nannan, Smith, Heather, Tian, Shin-Shay, Miller, Stephen G., Keenan, Richard M., Rosen, Jon, Dillon, Susan B., Lamb, Peter, Erickson-Miller, Connie L.

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