Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor Veliparib (ABT-888) in Combination with Irinotecan in Patients with A... by LoRusso, Patricia M, Li, Jing, Burger, Angelika, Heilbrun, Lance K, Sausville, Edward A, Boerner, Scott A, Smith, Daryn, Pilat, Mary Jo, Zhang, Jie, Tolaney, Sara M, Cleary, James M, Chen, Alice P, Rubinstein, Lawrence, Boerner, Julie L, Bowditch, Adam, Cai, Dongpo, Bell, Tracy, Wolanski, Andrew, Marrero, Allison M, Zhang, Yiping, Ji, Jiuping, Ferry-Galow, Katherine, Kinders, Robert J, Parchment, Ralph E, Shapiro, Geoffrey I

Get full text

Entering a Clinical Trial: Is it Right For You?: A Randomized Study of the Clinical Trials Video and Its Impact on the Informed Consent Process by HOFFNER, Brianna, BAUER-WU, Susan, HITCHCOCK-BRYAN, Suzanne, POWELL, Mark, WOLANSKI, Andrew, JOFFE, Steven

Get full text

Entering a clinical trial: Is it right for you? by Hoffner, Brianna, Bauer‐Wu, Susan, Hitchcock‐Bryan, Suzanne, Powell, Mark, Wolanski, Andrew, Joffe, Steven

Get full text

Abstract CT232: Phase I combination study of the CHK1 inhibitor prexasertib (LY2606368) and olaparib in patients with high-grade serous ovarian cancer and other advanced solid tumo... by Do, Khanh T., Hill, Sarah J., Kochupurakkal, Bose, Supko, Jeffrey G., Gannon, Courtney, Anderson, Adrienne, Muzikansky, Alona, Wolanski, Andrew, Hedglin, Jennifer, Parmar, Kalindi, Lazaro, Jean-Bernard, Liu, Joyce, Campos, Susana, Matulonis, Ursula A., D'Andrea, Alan D., Shapiro, Geoffrey I.

Get full text

Abstract CT037: Phase I safety, pharmacokinetic and pharmacodynamic study of CYC065, a cyclin dependent kinase inhibitor, in patients with advanced cancers (NCT02552953) by Do, Khanh T., Chau, Nicole, Wolanski, Andrew, Beardslee, Brian, Hassinger, Faith, Bhushan, Ketki, Pruitt-Thompson, Solida, Scotton, Amber, Frame, Sheelagh, Zheleva, Daniella I., Blake, David, Chiao, Judy, Shapiro, Geoffrey I.

Get full text

Abstract CT047: Phase 1 dose-escalation study of the CDK inhibitor dinaciclib in combination with the PARP inhibitor veliparib in patients with advanced solid tumors by Shapiro, Geoffrey I., Do, Khanh T., Tolaney, Sara M., Hilton, John F., Cleary, James M., Wolanski, Andrew, Beardslee, Brian, Hassinger, Faith, Bhushan, Ketki, Cai, Dongpo, Downey, Elizabeth, Pruitt-Thompson, Solida, Barry, Suzanne M., Kochupurakkal, Bose, Geradts, Joseph, Unitt, Christine, D'Andrea, Alan D., Muzikansky, Alona, Piekarz, Richard, Doyle, L. Austin, Supko, Jeffrey

Get full text

Abstract CT046: Phase I dose escalation study of the CDK4/6 inhibitor palbociclib in combination with the MEK inhibitor PD-0325901 in patients with RAS mutant solid tumors by Shapiro, Geoffrey I., Hilton, John, Gandi, Leena, Chau, Nicole, Cleary, James, Wolanski, Andrew, Anderson, Adrienne, Beardslee, Brian, Hassinger, Faith, Bhushan, Ketki, Downey, Elizabeth, Gibson, Joseph, Pruitt-Thompson, Solida, Muzikansky, Alona, Barry, Suzanne, Feeney, Nora, Paweletz, Cloud, Oxnard, Geoffrey, Supko, Jeffrey, Jänne, Pasi, Wong, Kwok-Kin, Johnson, Bruce

Get full text

Abstract 3157: Serial droplet digital PCR (ddPCR) of plasma cell-free DNA (cfDNA) as pharmacodynamic (PD) biomarker in Phase 1 clinical trials for patients (pts) with KRAS mutant n... by Paweletz, Cloud P., Oxnard, Geoffrey R., Feeney, Nora, Hilton, John F., Gandhi, Leena, Do, Khanh T., Anderson, Adrienne, Wolanski, Andrew, Tejeda, Alexander, English, Jessie M., Kirschmeier, Paul T., Jänne, Pasi A., Shapiro, Geoffrey I.

Get full text

Abstract LB-202: Responses to sequential sapacitabine and seliciclib in patients with BRCA-deficient solid tumors by Shapiro, Geoffrey I., Hilton, John, Cleary, James M., Tolaney, Sara M., Ghandi, Leena, Kwak, Eunice L., Clark, Jeffrey W., Wolanski, Andrew, Bell, Tracy, Schulz, John, Frame, Sheelagh, Saladino, Chiara, Hogben, Morag, Rodig, Scott J., Chiao, Judy H., Blake, David

Get full text

Road will ruin Serengeti by Dobson, Andrew P, Borner, Markus, Sinclair, Anthony R. E, Hudson, Peter J, Anderson, T. Michael, Bigurube, Gerald, Davenport, Tim B. B, Deutsch, James, Durant, Sarah M, Estes, Richard D, Estes, Anna B, Fryxell, John, Foley, Charles, Gadd, Michelle E, Haydon, Dan, Holdo, Ricardo, Holt, Robert D, Homewood, Katherine, Hopcraft, J. Grant C, Hilborn, Ray, Jambiya, George L. K, Laurenson, M. Karen, Melamari, Lota, Morindat, Alais Ole, Ogutu, Joseph O, Schaller, George, Wolanski, Eric

Get full text

Papyrus wetlands, nutrients balance, fisheries collapse, food security, and Lake Victoria level decline in 2000-2006 by Kiwango, Yustina Andrew, Wolanski, Eric

Get full text