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Discovery of UCB9386: A Potent, Selective, and Brain-Penetrant Nuak1 Inhibitor Suitable for In Vivo Pharmacological Studies
by
Poullennec, Karine G.
,
Jnoff, Eric
,
Abendroth, Jan
,
Bhuma, Naresh
,
Calmiano, Mark
,
Calmus, Laurent
,
Cardenas, Alvaro
,
Courade, Jean-Philippe
,
Delatour, Claude
,
Hall, Adrian
,
de Haro, Teresa
,
Delker, Silvia L.
,
Demaude, Thierry
,
Gaikwad, Nilesh
,
Ghavate, Dnyaneshwar
,
Gholap, Atul R.
,
Kierkowicz, Magdalena
,
Le Mestre, Régis
,
Van Hijfte, Nathalie
,
Verheijden, Simon
,
Vernerova, Katerina
,
De Wever, Veerle
,
Waghmode, Nivrutti
Published in
Journal of medicinal chemistry
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Journal Title
Journal Of Medicinal Chemistry
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Subjects
Animals
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Brain - Metabolism
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Chemistry, Medicinal
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Crystallography, X-Ray
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Drug Discovery
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Humans
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Life Sciences & Biomedicine
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Models, Molecular
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Pharmacology & Pharmacy
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Protein Kinase Inhibitors - Chemistry
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Protein Kinase Inhibitors - Pharmacokinetics
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Protein Kinase Inhibitors - Pharmacology
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Protein Kinases
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Protein Serine-Threonine Kinases - Antagonists & Inhibitors
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Protein Serine-Threonine Kinases - Metabolism
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Repressor Proteins
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Science & Technology
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Structure-Activity Relationship
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1400 : 2026
1400
2026
Source
Acs Crkn Legacy Archives
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American Chemical Society:jisc Collections:american Chemical Society Read & Publish Agreement 2022-2024 (Reading List)
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