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Six amino acid residues in a 1200 Å2 interface mediate binding of factor VIII to an IgG4κ inhibitory antibody
by
Lin, Jasper C
,
Ettinger, Ruth A
,
Schuman, Jason T
,
Zhang, Ai-Hong
,
Wamiq-Adhami, Muhammad
,
Nguyen, Phuong-Cac T
,
Nakaya-Fletcher, Shelley M
,
Puranik, Komal
,
Thompson, Arthur R
,
Pratt, Kathleen P
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PloS one
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Alanine
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Amino Acid Sequence
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Amino Acid Substitution
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Amino Acids
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Antibodies, Monoclonal - Metabolism
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Antigens
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Binding
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Binding Sites
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Biochemistry
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Coagulants
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Coagulation Factors
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Crystal Structure
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Epitopes
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Epitopes - Chemistry
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Factor Viii - Chemistry
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Factor Viii - Genetics
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Factor Viii - Metabolism
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Factor Viii Deficiency
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