Peptide mimetic compounds can activate or inhibit cardiac and skeletal ryanodine receptors by Robinson, Ken, Culley, Dane, Waring, Sam, Lamb, Graham D., Easton, Christopher, Casarotto, Marco G., Dulhunty, Angela F.

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Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR) by Ward, Richard A, Anderton, Mark J, Ashton, Susan, Bethel, Paul A, Box, Matthew, Butterworth, Sam, Colclough, Nicola, Chorley, Christopher G, Chuaqui, Claudio, Cross, Darren A. E, Dakin, Les A, Debreczeni, Judit É, Eberlein, Cath, Finlay, M. Raymond V, Hill, George B, Grist, Matthew, Klinowska, Teresa C. M, Lane, Clare, Martin, Scott, Orme, Jonathon P, Smith, Peter, Wang, Fengjiang, Waring, Michael J

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Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor by Finlay, M. Raymond V, Anderton, Mark, Ashton, Susan, Ballard, Peter, Bethel, Paul A, Box, Matthew R, Bradbury, Robert H, Brown, Simon J, Butterworth, Sam, Campbell, Andrew, Chorley, Christopher, Colclough, Nicola, Cross, Darren A. E, Currie, Gordon S, Grist, Matthew, Hassall, Lorraine, Hill, George B, James, Daniel, James, Michael, Kemmitt, Paul, Klinowska, Teresa, Lamont, Gillian, Lamont, Scott G, Martin, Nathaniel, McFarland, Heather L, Mellor, Martine J, Orme, Jonathon P, Perkins, David, Perkins, Paula, Richmond, Graham, Smith, Peter, Ward, Richard A, Waring, Michael J, Whittaker, David, Wells, Stuart, Wrigley, Gail L

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Sustained year-round oceanographic measurements from Rothera Research Station, Antarctica, 1997–2017 by Venables, Hugh, Meredith, Michael P., Hendry, Katharine R., ten Hoopen, Petra, Peat, Helen, Chapman, Alice, Beaumont, Jennifer, Piper, Rayner, Miller, Andrew J., Mann, Paul, Rossetti, Helen, Massey, Ali, Souster, Terri, Reeves, Simon, Fenton, Mairi, Heiser, Sabrina, Pountney, Sam, Reed, Sarah, Waring, Zoë, Clark, Marlon, Bolton, Emma, Mathews, Ryan, London, Hollie, Clement, Alice, Stuart, Emma, Reichardt, Aurelia, Brandon, Mark, Leng, Melanie, Arrowsmith, Carol, Annett, Amber, Henley, Sian F., Clarke, Andrew

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Hazardous, harmful, and dependent alcohol use in healthcare professionals: a systematic review and meta-analysis by Halsall, Lauren, Irizar, Patricia, Burton, Sam, Waring, Sara, Giles, Susan, Goodwin, Laura, Jones, Andrew

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The structure-guided discovery of osimertinib: the first U.S. FDA approved mutant selective inhibitor of EGFR T790M by Butterworth, Sam, Cross, Darren A E, Finlay, M Raymond V, Ward, Richard A, Waring, Michael J

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The transcriptomic response of Streptococcus pneumoniae following exposure to cigarette smoke extract by Manna, Sam, Waring, Alicia, Papanicolaou, Angelica, Hall, Nathan E., Bozinovski, Steven, Dunne, Eileen M., Satzke, Catherine

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Perioperative critical events and morbidity associated with anesthesia in early life: Subgroup analysis of United Kingdom participation in the NEonate and Children audiT of Anaesth... by Walker, Suellen M., Engelhardt, Thomas, Ahmad, Nargis, Dobby, Nadine, Anderson, Brian, Kuchi, Sridevi, Masip, Nuria, Brooks, Peter, Hare, Alison, Casey, Michelle, Silva, Sam De, Krishnan, Prakash, Sogbodjor, L Amaki, Walker, Ellie, King, Stephanie, Nicholson, Katy, Quinney, Michelle, Stevens, Paul, Blevin, Andrew, Giombini, Mariangela, Goonasekera, Chulananda, Adil, Sadia, Bew, Stephanie, Bodlani, Carol, Gilpin, Dan, Jinks, Stephanie, Malarkkan, Nalini, Miskovic, Alice, Pad, Rebecca, Barry, Juliet W., Abbott, Joy, Armstrong, James, Cooper, Natalie, Crate, Lindsay, Emery, John, James, Kathryn, King, Hannah, Martin, Paul, Catenacci, Stefano S., Bomont, Rob, Smith, Paul, Mele, Sara, Verzelloni, Alessandra, Dix, Philippa, Bell, Graham, Gordeva, Elena, McKee, Lesley, Ngan, Esther, Scheffczik, Jutta, Tan, Li‐En, Worrall, Mark, Cassar, Carmel, Goddard, Kevin, Barlow, Victoria, Oshan, Vimmi, Shah, Khairi, Bell, Sarah, Daniels, Lisa, Gandhi, Monica, Pachter, David, Perry, Chris, Robertson, Andrew, Scott, Carmen, Waring, Lynne, Barnes, David, Childs, Sophie, Norman, Joanne, Sunderland, Robin, Disma, Nicola, Veyckemans, Francis, Virag, Katalin, Hansen, Tom G., Becke, Karin, Harlet, Pierre, Vutskits, Laszlo, Walker, Suellen M., Graaff, Jurgen C. de, Zielinska, Marzena, Simic, Dusica, Engelhardt, Thomas, Habre, Walid

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The structure-guided discovery of osimertinib: the first U.S. FDA approved mutant selective inhibitor of EGFR T790MThe authors declare no competing interests by Butterworth, Sam, Cross, Darren A. E, Finlay, M. Raymond V, Ward, Richard A, Waring, Michael J

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The structure-guided discovery of osimertinib: the first U.S. FDA approved mutant selective inhibitor of EGFR T790M† †The authors declare no competing interests by Butterworth, Sam, Cross, Darren A. E., Finlay, M. Raymond V., Ward, Richard A., Waring, Michael J.

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Abstract 4744: Structure-based development of covalent inhibitors of the activating and T790M gatekeeper mutant forms of the epidermal growth factor receptor (EGFR) leading to the... by Ward, Richard A., Ashton, Susan, Anderton, Mark, Ballard, Pete G., Bradbury, Rob H., Butterworth, Sam, Colclough, Nicola, Cross, Darren A E, Finlay, M Ray V., McFarland, Heather L., Mellor, Martine, Waring, Mike J.

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Property based optimisation of glucokinase activators – discovery of the phase IIb clinical candidate AZD1656 by Waring, Michael J., Clarke, David S., Fenwick, Mark D., Godfrey, Linda, Groombridge, Sam D., Johnstone, Craig, McKerrecher, Darren, Pike, Kurt G., Rayner, John W., Robb, Graeme R., Wilson, Ingrid

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Abstract B94: Discovery of and first disclosure of the clinical candidate AZD9291, a potent and selective third-generation EGFR inhibitor of both activating and T790M resistant mut... by Finlay, M. Raymond V., Anderton, Mark, Ashton, Susan, Ballard, Peter G., Bradbury, Rob H., Butterworth, Sam, Chuaqui, Claudio E., Colclough, Nicola, Cross, Darren A. E., McFarland, Heather L., Mellor, Martine J., Ward, Richard A., Waring, Mike J.

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Discovery of a series of 2-(pyridinyl)pyrimidines as potent antagonists of GPR40 by Waring, Michael J., Baker, David J., Bennett, Stuart N. L., Dossetter, Alexander G., Fenwick, Mark, Garcia, Rob, Georgsson, Jennie, Groombridge, Sam D., Loxham, Susan, MacFaul, Philip A., Maskill, Katie G., Morgan, David, Morrell, Jenny, Pointon, Helen, Robb, Graeme R., Smith, David M., Stokes, Stephen, Wilkinson, Gary

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Discovery of a series of 2-(pyridinyl)pyrimidines as potent antagonists of GPR40Electronic supplementary information (ESI) available: Data tables for additional compounds, experime... by Waring, Michael J, Baker, David J, Bennett, Stuart N. L, Dossetter, Alexander G, Fenwick, Mark, Garcia, Rob, Georgsson, Jennie, Groombridge, Sam D, Loxham, Susan, MacFaul, Philip A, Maskill, Katie G, Morgan, David, Morrell, Jenny, Pointon, Helen, Robb, Graeme R, Smith, David M, Stokes, Stephen, Wilkinson, Gary

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Novel Cytotoxic Oxopyridoindolizines: iso-Propyl-7,8,9-trichloro-6,7,8,9-tetrahydro-5-oxopyrido[2,3-a]-indolizine-10-carboxylates (OPIC) by Zunino, Franco, Kotchevar, Ann T., Waring, Michael, Daoudi, Maria, Larbi, Najib Ben, Mimouni, Mostafa, Sam, Najat, Zahidi, Assou, Ben-Hadda, Taibi

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Property based optimisation of glucokinase activators - discovery of the phase IIb clinical candidate AZD1656Electronic supplementary information (ESI) available: Assay protocols,... by Waring, Michael J, Clarke, David S, Fenwick, Mark D, Godfrey, Linda, Groombridge, Sam D, Johnstone, Craig, McKerrecher, Darren, Pike, Kurt G, Rayner, John W, Robb, Graeme R, Wilson, Ingrid

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Novel Cytotoxic Oxopyridoindolizines: iso-Propyl-7,8,9-tri-chloro-6,7,8,9-tetrahydro-5-oxopyrido[2,3-a]-indolizine-10-carboxylates (OPIC) by Zunino, Franco, Kotchevar, Ann T., Waring, Michael, Daoudi, Maria, Larbi, Najib Ben, Mimouni, Mostafa, Sam, Najat, Zahidi, Assou, Ben-Hadda, Taibi

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