Abstract WP354: Neurovascular Advanced Practice Clinicians - A New Paradigm for Continuity in Acute Stroke Care by Paolucci, Gino A, Fuller, Lindsey R, Oliver, Lori A, Quinn, Katie A, Watkins, Christina C, Clark, Michael L, McTaggart, Ryan A, Jayaraman, Mahesh, Saad, Ali

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Abstract TP227: Emergency Medical Systems Education May Improve Compliance With Pre-Hospital Stroke Triage Protocols by Dibiasio, Eleanor L, Oliver, Lori A, Paolucci, Gino A, Clark, Michael L, Watkins, Christina C, Wilks, Ann, DeLisi, Karen, Yaghi, Shadi, Hemendinger, Morgan, Baird, Grayson, Jayaraman, Mahesh V, McTaggart, Ryan A

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Scalable continuous evolution for the generation of diverse enzyme variants encompassing promiscuous activities by Rix, Gordon, Watkins-Dulaney, Ella J., Almhjell, Patrick J., Boville, Christina E., Arnold, Frances H., Liu, Chang C.

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Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial by Brown, Paul D, Pugh, Stephanie, Laack, Nadia N, Wefel, Jeffrey S, Khuntia, Deepak, Meyers, Christina, Choucair, Ali, Fox, Sherry, Suh, John H, Roberge, David, Kavadi, Vivek, Bentzen, Soren M, Mehta, Minesh P, Watkins-Bruner, Deborah

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Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective by Kenna, J. Gerry, Taskar, Kunal S., Battista, Christina, Bourdet, David L., Brouwer, Kim L.R., Brouwer, Kenneth R., Dai, David, Funk, Christoph, Hafey, Michael J., Lai, Yurong, Maher, Jonathan, Pak, Y. Anne, Pedersen, Jenny M., Polli, Joseph W., Rodrigues, A. David, Watkins, Paul B., Yang, Kyunghee, Yucha, Robert W.

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Stability of SARS-CoV-2 RNA in Nonsupplemented Saliva by Ott, Isabel M, Strine, Madison S, Watkins, Anne E, Boot, Maikel, Kalinich, Chaney C, Harden, Christina A, Vogels, Chantal B F, Casanovas-Massana, Arnau, Moore, Adam J, Muenker, M Catherine, Nakahata, Maura, Tokuyama, Maria, Nelson, Allison, Fournier, John, Bermejo, Santos, Campbell, Melissa, Datta, Rupak, Dela Cruz, Charles S, Farhadian, Shelli F, Ko, Albert I, Iwasaki, Akiko, Grubaugh, Nathan D, Wilen, Craig B, Wyllie, Anne L

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Analysis of protein-coding genetic variation in 60,706 humans by Lek, Monkol, Karczewski, Konrad J., Minikel, Eric V., Samocha, Kaitlin E., Banks, Eric, Fennell, Timothy, O’Donnell-Luria, Anne H., Ware, James S., Hill, Andrew J., Cummings, Beryl B., Tukiainen, Taru, Birnbaum, Daniel P., Kosmicki, Jack A., Duncan, Laramie E., Estrada, Karol, Zhao, Fengmei, Zou, James, Pierce-Hoffman, Emma, Berghout, Joanne, Cooper, David N., Deflaux, Nicole, DePristo, Mark, Do, Ron, Flannick, Jason, Fromer, Menachem, Gauthier, Laura, Goldstein, Jackie, Gupta, Namrata, Howrigan, Daniel, Kiezun, Adam, Kurki, Mitja I., Moonshine, Ami Levy, Natarajan, Pradeep, Orozco, Lorena, Peloso, Gina M., Poplin, Ryan, Rivas, Manuel A., Ruano-Rubio, Valentin, Rose, Samuel A., Ruderfer, Douglas M., Shakir, Khalid, Stenson, Peter D., Stevens, Christine, Thomas, Brett P., Tiao, Grace, Tusie-Luna, Maria T., Weisburd, Ben, Won, Hong-Hee, Yu, Dongmei, Altshuler, David M., Ardissino, Diego, Boehnke, Michael, Danesh, John, Donnelly, Stacey, Elosua, Roberto, Florez, Jose C., Gabriel, Stacey B., Getz, Gad, Glatt, Stephen J., Hultman, Christina M., Kathiresan, Sekar, Laakso, Markku, McCarroll, Steven, McCarthy, Mark I., McGovern, Dermot, McPherson, Ruth, Neale, Benjamin M., Palotie, Aarno, Purcell, Shaun M., Saleheen, Danish, Scharf, Jeremiah M., Sklar, Pamela, Sullivan, Patrick F., Tuomilehto, Jaakko, Tsuang, Ming T., Watkins, Hugh C., Wilson, James G., Daly, Mark J., MacArthur, Daniel G.

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Ribbon scanning confocal for high-speed high-resolution volume imaging of brain by Watson, Alan M, Rose, Annika H, Gibson, Gregory A, Gardner, Christina L, Sun, Chengqun, Reed, Douglas S, Lam, L K Metthew, St Croix, Claudette M, Strick, Peter L, Klimstra, William B, Watkins, Simon C

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A structural variation reference for medical and population genetics by Collins, Ryan L., Brand, Harrison, Karczewski, Konrad J., Zhao, Xuefang, Alföldi, Jessica, Francioli, Laurent C., Khera, Amit V., Lowther, Chelsea, Gauthier, Laura D., Wang, Harold, Watts, Nicholas A., Solomonson, Matthew, O’Donnell-Luria, Anne, Baumann, Alexander, Munshi, Ruchi, Walker, Mark, Whelan, Christopher W., Huang, Yongqing, Brookings, Ted, Sharpe, Ted, Stone, Matthew R., Valkanas, Elise, Fu, Jack, Tiao, Grace, Laricchia, Kristen M., Ruano-Rubio, Valentin, Stevens, Christine, Gupta, Namrata, Cusick, Caroline, Margolin, Lauren, Taylor, Kent D., Lin, Henry J., Rich, Stephen S., Post, Wendy S., Chen, Yii-Der Ida, Rotter, Jerome I., Nusbaum, Chad, Philippakis, Anthony, Lander, Eric, Gabriel, Stacey, Neale, Benjamin M., Kathiresan, Sekar, Daly, Mark J., Banks, Eric, MacArthur, Daniel G., Talkowski, Michael E.

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Diverse functional autoantibodies in patients with COVID-19 by Wang, Eric Y., Mao, Tianyang, Klein, Jon, Dai, Yile, Huck, John D., Jaycox, Jillian R., Liu, Feimei, Zhou, Ting, Israelow, Benjamin, Wong, Patrick, Coppi, Andreas, Lucas, Carolina, Silva, Julio, Oh, Ji Eun, Song, Eric, Perotti, Emily S., Zheng, Neil S., Fischer, Suzanne, Campbell, Melissa, Fournier, John B., Wyllie, Anne L., Vogels, Chantal B. F., Ott, Isabel M., Kalinich, Chaney C., Petrone, Mary E., Watkins, Anne E., Dela Cruz, Charles, Farhadian, Shelli F., Schulz, Wade L., Ma, Shuangge, Grubaugh, Nathan D., Ko, Albert I., Iwasaki, Akiko, Ring, Aaron M.

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Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network by Aliota, Matthew T., Bassit, Leda, Bradrick, Shelton S., Cox, Bryan, Garcia-Blanco, Mariano A., Gavegnano, Christina, Friedrich, Thomas C., Golos, Thaddeus G., Griffin, Diane E., Haddow, Andrew D., Kallas, Esper G., Kitron, Uriel, Lecuit, Marc, Magnani, Diogo M., Marrs, Caroline, Mercer, Natalia, McSweegan, Edward, Ng, Lisa F.P., O'Connor, David H., Osorio, Jorge E., Ribeiro, Guilherme S., Ricciardi, Michael, Rossi, Shannan L., Saade, George, Schinazi, Raymond F., Schott-Lerner, Geraldine O., Shan, Chao, Shi, Pei-Yong, Watkins, David I., Vasilakis, Nikos, Weaver, Scott C.

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Mycophenolate mofetil in dermatology by Orvis, Alissa K., BS, Wesson, Stanton K., MD, Breza, Thomas S., MD, Church, Ann A., MD, Mitchell, Christina L., MD, Watkins, Shannon W., MD

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Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies by Sarwar, Nadeem, Butterworth, Adam S, Freitag, Daniel F, Gregson, John, Willeit, Peter, Gorman, Donal N, Gao, Pei, Saleheen, Danish, Rendon, Augusto, Nelson, Christopher P, Braund, Peter S, Hall, Alistair S, Chasman, Daniel I, Tybjærg-Hansen, Anne, Chambers, John C, Benjamin, Emelia J, Franks, Paul W, Clarke, Robert, Wilde, Arthur A M, Trip, Mieke D, Steri, Maristella, Witteman, Jacqueline C M, Qi, Lu, van der Schoot, C Ellen, de Faire, Ulf, Erdmann, Jeanette, Stringham, Heather M, Koenig, Wolfgang, Rader, Daniel J, Melzer, David, Reich, David, Psaty, Bruce M, Kleber, Marcus E, Panagiotakos, Demosthenes B, Willeit, Johann, Wennberg, Patrik, Woodward, Mark, Adamovic, Svetlana, Rimm, Eric B, Meade, Tom W, Gillum, Richard F, Shaffer, Jonathan A, Hofman, Albert, Onat, Altan, Sundström, Johan, Wassertheil-Smoller, Sylvia, Mellström, Dan, Gallacher, John, Cushman, Mary, Tracy, Russell P, Kauhanen, Jussi, Karlsson, Magnus, Salonen, Jukka T, Wilhelmsen, Lars, Amouyel, Philippe, Cantin, Bernard, Best, Lyle G, Ben-Shlomo, Yoav, Manson, JoAnn E, Davey-Smith, George, de Bakker, Paul I W, O'Donnell, Christopher J, Wilson, James F, Wilson, Anthony G, Assimes, Themistocles L, Jansson, John-Olov, Ohlsson, Claes, Tivesten, Åsa, Ljunggren, Östen, Reilly, Muredach P, Hamsten, Anders, Ingelsson, Erik, Cambien, Francois, Hung, Joseph, Thomas, G Neil, Boehnke, Michael, Schunkert, Heribert, Asselbergs, Folkert W, Kastelein, John J P, Gudnason, Vilmundur, Salomaa, Veikko, Harris, Tamara B, Kooner, Jaspal S, Allin, Kristine H, Nordestgaard, Børge G, Hopewell, Jemma C, Goodall, Alison H, Ridker, Paul M, Hólm, Hilma, Watkins, Hugh, Ouwehand, Willem H, Samani, Nilesh J, Kaptoge, Stephen, Di Angelantonio, Emanuele, Harari, Olivier, Danesh, John

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Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial by Perry, David, Dinsmore, Lynn, Kambafwile, Mary, Idrovo, Luis, Hurley, Lisa, Kerwood, Lauriane, Merritt, Carley, Duty, Suzanna, Lindert, Ralf, Meegada, Madana, Maguire, Holly, Hiden, Joanne, Brodie, Fiona, Barcroft, Heather, Wightman, John, O Neill, Mark, Siddiqui, Amber, Rashmi, Sindhu, Wilson, Laura, Cullen, Claire, Keeling, Alison, Hindle, Julia, Maguire, Stuart, Hamid, Umair, Gaba, Waqar, Mohammed, Niaz, Robinson, Rianne, Mathieson, Philip, Jones, Val, Lush, Audrey, Bell, Jo, Badiani, Bhavna, Guo, Fenglin, Chamberlain, Angela, Donaldson, Dave, Melikyan, Elina, Oconnell, Susan, Hurdowar, Steve, Johnson, Matthew, Moore, Kimberley, Stevens, Angela, Burnip, Rachel, Beranova, Eva, Walker, Susannah, Cain, Rebecca, Willmot, Mark, Bates, Michelle, Pitt Ford, Alexandra, Aubrey, Beth, Howard, Joanne, Dhar, Saikat, Howard-Brown, Jennifer, Imam, Javed, Whitworth, Simon, Mcgee, Joanne, Hannon, Niamh, Mokoena, Langanani, Smart, Amanda, Donaldson, Fiona, Graham, Libby, Rowe, Joy, Munuswamy Vaiyapuri, Elangovan, Thomas, Lisa, Sharon, Storton, Jones, Paul, Johnston, Stuart, Pusalkar, Aparna, Broughton, David, Tryambake, Dinesh, Skotnicka, Agnieszka, Thompson, Jane, Annamalai, Arunkumar, Wilkinson, Peter, Young, Emma, Pereira, Rita, Drummond, Graham, Austin, Duncan, Funnell, Sarah, Jones, Stephanie, Vassallo, Joseph, Leonard, Dee, Wynter, Inez, Janbieh, Joumana, Wade, Lynne, Otter, Linda, Fleming, Amy, Jones, Rhian, Williams, Richard, Mavinamane, Sunanda, Hunt, Lorraine, Haque, Kashif, Gibson, Elspeth, Neves-Silva, Yara, Thompson, Alastair, Ritchings, Andrew, Mcredmond, Catherine, Goulding, Alicia, Punnoose, Sunil, Gordon, Laura, Tarkas, Tillana

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Quantifying prion disease penetrance using large population control cohorts by Minikel, Eric Vallabh, Vallabh, Sonia M, Lek, Monkol, Estrada, Karol, Samocha, Kaitlin E, Sathirapongsasuti, J Fah, McLean, Cory Y, Tung, Joyce Y, Yu, Linda P C, Gambetti, Pierluigi, Blevins, Janis, Zhang, Shulin, Cohen, Yvonne, Chen, Wei, Yamada, Masahito, Hamaguchi, Tsuyoshi, Sanjo, Nobuo, Mizusawa, Hidehiro, Nakamura, Yosikazu, Kitamoto, Tetsuyuki, Collins, Steven J, Boyd, Alison, Will, Robert G, Knight, Richard, Ponto, Claudia, Zerr, Inga, Kraus, Theo F J, Eigenbrod, Sabina, Giese, Armin, Calero, Miguel, de Pedro-Cuesta, Jesús, Haïk, Stéphane, Laplanche, Jean-Louis, Bouaziz-Amar, Elodie, Brandel, Jean-Philippe, Capellari, Sabina, Parchi, Piero, Poleggi, Anna, Ladogana, Anna, O'Donnell-Luria, Anne H, Karczewski, Konrad J, Marshall, Jamie L, Boehnke, Michael, Laakso, Markku, Mohlke, Karen L, Kähler, Anna, Chambert, Kimberly, McCarroll, Steven, Sullivan, Patrick F, Hultman, Christina M, Purcell, Shaun M, Sklar, Pamela, van der Lee, Sven J, Rozemuller, Annemieke, Jansen, Casper, Hofman, Albert, Kraaij, Robert, van Rooij, Jeroen G J, Ikram, M Arfan, Uitterlinden, André G, van Duijn, Cornelia M, Daly, Mark J, MacArthur, Daniel G

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Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets by Lempiäinen, Harri, Brænne, Ingrid, Michoel, Tom, Tragante, Vinicius, Vilne, Baiba, Webb, Tom R., Kyriakou, Theodosios, Eichner, Johannes, Zeng, Lingyao, Willenborg, Christina, Franzen, Oscar, Ruusalepp, Arno, Goel, Anuj, van der Laan, Sander W., Biegert, Claudia, Hamby, Stephen, Talukdar, Husain A., Foroughi Asl, Hassan, Pasterkamp, Gerard, Watkins, Hugh, Samani, Nilesh J., Wittenberger, Timo, Erdmann, Jeanette, Schunkert, Heribert, Asselbergs, Folkert W., Björkegren, Johan L. M.

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Mitochondrial H2O2 in Lung Antigen-Presenting Cells Blocks NF-κB Activation to Prevent Unwarranted Immune Activation by Khare, Anupriya, Raundhal, Mahesh, Chakraborty, Krishnendu, Das, Sudipta, Corey, Catherine, Kamga, Christelle K., Quesnelle, Kelly, St. Croix, Claudette, Watkins, Simon C., Morse, Christina, Oriss, Timothy B., Huff, Rachael, Hannum, Rachel, Ray, Prabir, Shiva, Sruti, Ray, Anuradha

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Evaluating drug targets through human loss-of-function genetic variation by Minikel, Eric Vallabh, Karczewski, Konrad J., Martin, Hilary C., Cummings, Beryl B., Whiffin, Nicola, Rhodes, Daniel, Alföldi, Jessica, Trembath, Richard C., van Heel, David A., Daly, Mark J., Schreiber, Stuart L., MacArthur, Daniel G.

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Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes by Wang, Qingbo, Pierce-Hoffman, Emma, Cummings, Beryl B., Alföldi, Jessica, Francioli, Laurent C., Gauthier, Laura D., Hill, Andrew J., O’Donnell-Luria, Anne H., Karczewski, Konrad J., MacArthur, Daniel G.

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Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease: A Genome-Wide Analysis of Common Variants by DICHGANS, Martin, MALIK, Rainer, O'DONNELL, Christopher J, FORNAGE, Myriam, THORSTEINSDOTTIR, Unnur, PSATY, Bruce M, HENGSTENBERG, Christian, SESHADRI, Sudha, ERDMANN, Jeanette, BIS, Joshua C, PETERS, Annette, BONCORAGLIO, Giorgio B, KÖNIG, Inke R, MÄRZ, Winfried, MESCHIA, James F, KATHIRESAN, Sekar, IKRAM, M. Arfan, McPHERSON, Ruth, STEFANSSON, Kari, SUDLOW, Cathie, REILLY, Muredach P, THOMPSON, John R, SHARMA, Pankaj, ROSAND, Jonathan, HOPEWELL, Jemma C, CHAMBERS, John C, WATKINS, Hugh, ROTHWELL, Peter M, ROBERTS, Robert, MARKUS, Hugh S, SAMANI, Nilesh J, FARRALL, Martin, SCHUNKERT, Heribert, CLARKE, Robert, GRETARSDOTTIR, Solveig, THORLEIFSSON, Gudmar, MITCHELL, Braxton D, ASSIMES, Themistocles L, LEVI, Christopher

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