The humpty dumpty effect: Emerging media diffusion and (Granger) causal democratic change in 122 countries from 1946 to 2014 by Wertz, Blake, Groshek, Jacob, Rochefort, Alex

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The Search for Consumers of Web-Based Raw DNA Interpretation Services: Using Social Media to Target Hard-to-Reach Populations by Cahill, Tiernan J, Wertz, Blake, Zhong, Qiankun, Parlato, Andrew, Donegan, John, Forman, Rebecca, Manot, Supriya, Wu, Tianyi, Xu, Yazhu, Cummings, James J, Norkunas Cunningham, Tricia, Wang, Catharine

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Consumer use and response to online third‐party raw DNA interpretation services by Wang, Catharine, Cahill, Tiernan J., Parlato, Andrew, Wertz, Blake, Zhong, Qiankun, Cunningham, Tricia Norkunas, Cummings, James J.

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Correction: The Search for Consumers of Web-Based Raw DNA Interpretation Services: Using Social Media to Target Hard-to-Reach Populations by Cahill, Tiernan J, Wertz, Blake, Zhong, Qiankun, Parlato, Andrew, Donegan, John, Forman, Rebecca, Manot, Supriya, Wu, Tianyi, Xu, Yazhu, Cummings, James J, Norkunas Cunningham, Tricia, Wang, Catharine

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Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility by Guan, Jane, Zhou, Wei, Hafner, Marc, Blake, Robert A., Chalouni, Cecile, Chen, Irene P., De Bruyn, Tom, Giltnane, Jennifer M., Hartman, Steven J., Heidersbach, Amy, Houtman, Rene, Ingalla, Ellen, Kategaya, Lorn, Kleinheinz, Tracy, Li, Jun, Martin, Scott E., Modrusan, Zora, Nannini, Michelle, Oeh, Jason, Ubhayakar, Savita, Wang, Xiaojing, Wertz, Ingrid E., Young, Amy, Yu, Mamie, Sampath, Deepak, Hager, Jeffrey H., Friedman, Lori S., Daemen, Anneleen, Metcalfe, Ciara

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USP7 small-molecule inhibitors interfere with ubiquitin binding by Kategaya, Lorna, Di Lello, Paola, Rougé, Lionel, Pastor, Richard, Clark, Kevin R., Drummond, Jason, Kleinheinz, Tracy, Lin, Eva, Upton, John-Paul, Prakash, Sumit, Heideker, Johanna, McCleland, Mark, Ritorto, Maria Stella, Alessi, Dario R., Trost, Matthias, Bainbridge, Travis W., Kwok, Michael C. M., Ma, Taylur P., Stiffler, Zachary, Brasher, Bradley, Tang, Yinyan, Jaishankar, Priyadarshini, Hearn, Brian R., Renslo, Adam R., Arkin, Michelle R., Cohen, Frederick, Yu, Kebing, Peale, Frank, Gnad, Florian, Chang, Matthew T., Klijn, Christiaan, Blackwood, Elizabeth, Martin, Scott E., Forrest, William F., Ernst, James A., Ndubaku, Chudi, Wang, Xiaojing, Beresini, Maureen H., Tsui, Vickie, Schwerdtfeger, Carsten, Blake, Robert A., Murray, Jeremy, Maurer, Till, Wertz, Ingrid E.

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GDC-9545 (Giredestrant): A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer by Liang, Jun, Zbieg, Jason R., Blake, Robert A., Chang, Jae H., Daly, Stephen, DiPasquale, Antonio G., Friedman, Lori S., Gelzleichter, Thomas, Gill, Matthew, Giltnane, Jennifer M., Goodacre, Simon, Guan, Jane, Hartman, Steven J., Ingalla, Ellen Rei, Kategaya, Lorn, Kiefer, James R., Kleinheinz, Tracy, Labadie, Sharada S., Lai, Tommy, Li, Jun, Liao, Jiangpeng, Liu, Zhiguo, Mody, Vidhi, McLean, Neville, Metcalfe, Ciara, Nannini, Michelle A., Oeh, Jason, O’Rourke, Martin G., Ortwine, Daniel F., Ran, Yingqing, Ray, Nicholas C., Roussel, Fabien, Sambrone, Amy, Sampath, Deepak, Schutt, Leah K., Vinogradova, Maia, Wai, John, Wang, Tao, Wertz, Ingrid E., White, Jonathan R., Yeap, Siew Kuen, Young, Amy, Zhang, Birong, Zheng, Xiaoping, Zhou, Wei, Zhong, Yu, Wang, Xiaojing

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Antibody-mediated delivery of chimeric protein degraders which target estrogen receptor alpha (ERα) by Dragovich, Peter S., Adhikari, Pragya, Blake, Robert A., Blaquiere, Nicole, Chen, Jinhua, Cheng, Yun-Xing, den Besten, Willem, Han, Jinping, Hartman, Steven J., He, Jintang, He, Mingtao, Rei Ingalla, Ellen, Kamath, Amrita V., Kleinheinz, Tracy, Lai, Tommy, Leipold, Douglas D., Li, Chun Sing, Liu, Qi, Lu, Jiawei, Lu, Ying, Meng, Fanwei, Meng, Lingyao, Ng, Carl, Peng, Kaishan, Lewis Phillips, Gail, Pillow, Thomas H., Rowntree, Rebecca K., Sadowsky, Jack D., Sampath, Deepak, Staben, Leanna, Staben, Steven T., Wai, John, Wan, Kunpeng, Wang, Xinxin, Wei, BinQing, Wertz, Ingrid E., Xin, Jianfeng, Xu, Keyang, Yao, Hui, Zang, Richard, Zhang, Donglu, Zhou, Hao, Zhao, Yongxin

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The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer by Joseph, James D, Darimont, Beatrice, Zhou, Wei, Arrazate, Alfonso, Young, Amy, Ingalla, Ellen, Walter, Kimberly, Blake, Robert A, Nonomiya, Jim, Guan, Zhengyu, Kategaya, Lorna, Govek, Steven P, Lai, Andiliy G, Kahraman, Mehmet, Brigham, Dan, Sensintaffar, John, Lu, Nhin, Shao, Gang, Qian, Jing, Grillot, Kate, Moon, Michael, Prudente, Rene, Bischoff, Eric, Lee, Kyoung-Jin, Bonnefous, Celine, Douglas, Karensa L, Julien, Jackaline D, Nagasawa, Johnny Y, Aparicio, Anna, Kaufman, Josh, Haley, Benjamin, Giltnane, Jennifer M, Wertz, Ingrid E, Lackner, Mark R, Nannini, Michelle A, Sampath, Deepak, Schwarz, Luis, Manning, Henry Charles, Tantawy, Mohammed Noor, Arteaga, Carlos L, Heyman, Richard A, Rix, Peter J, Friedman, Lori, Smith, Nicholas D, Metcalfe, Ciara, Hager, Jeffrey H

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Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques by Di Lello, Paola, Pastor, Richard, Murray, Jeremy M, Blake, Robert A, Cohen, Frederick, Crawford, Terry D, Drobnick, Joy, Drummond, Jason, Kategaya, Lorna, Kleinheinz, Tracy, Maurer, Till, Rougé, Lionel, Zhao, Xianrui, Wertz, Ingrid, Ndubaku, Chudi, Tsui, Vickie

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Conjugation of Indoles to Antibodies through a Novel Self‐Immolating Linker by Dragovich, Peter S., Blake, Robert A., Chen, Chunjiao, Chen, Jinhua, Chuh, Josefa, den Besten, Willem, Fan, Fang, Fourie, Aimee, Hartman, Steven J., He, Changrong, He, Jintang, Ingalla, Ellen Rei, Kozak, Katherine R., Leong, Steven R., Lu, Jiawei, Ma, Yong, Meng, Lingyao, Nannini, Michelle, Oeh, Jason, Ohri, Rachana, Lewis Phillips, Gail, Pillow, Thomas H., Rowntree, Rebecca K., Sampath, Deepak, Vandlen, Richard, Vollmar, Breanna, Wai, John, Wertz, Ingrid E., Xu, Keyang, Xu, Zijin, Zhang, Donglu

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Abstract 3406: GDC-9545: A pure antiestrogen clinical candidate that immobilizes the estrogen receptor and profoundly alters chromatin accessibility in vivo by Metcalfe, Ciara, Zhou, Wei, Guan, Jane, Blake, Robert A., De Bruyn, Tom, Giltnane, Jennifer M., Ingalla, Ellen, Kleinheinz, Tracy, Liang, Jun, Mody, Vidhi, Oeh, Jason, Ubhayakar, Savita, Wertz, Ingrid, Young, Amy, Zbieg, Jason, Wang, Xiaojing, Hafner, Marc

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Correction: The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer by Joseph, James D, Darimont, Beatrice, Zhou, Wei, Arrazate, Alfonso, Young, Amy, Ingalla, Ellen, Walter, Kimberly, Blake, Robert A, Nonomiya, Jim, Guan, Zhengyu, Kategaya, Lorna, Govek, Steven P, Lai, Andiliy G, Kahraman, Mehmet, Brigham, Dan, Sensintaffar, John, Lu, Nhin, Shao, Gang, Qian, Jing, Grillot, Kate, Moon, Michael, Prudente, Rene, Bischoff, Eric, Lee, Kyoung-Jin, Bonnefous, Celine, Douglas, Karensa L, Julien, Jackaline D, Nagasawa, Johnny Y, Aparicio, Anna, Kaufman, Josh, Haley, Benjamin, Giltnane, Jennifer M, Wertz, Ingrid E, Lackner, Mark R, Nannini, Michelle A, Sampath, Deepak, Schwarz, Luis, Manning, Henry Charles, Tantawy, Mohammed Noor, Arteaga, Carlos L, Heyman, Richard A, Rix, Peter J, Friedman, Lori, Smith, Nicholas D, Metcalfe, Ciara, Hager, Jeffrey H

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Abstract P5-04-07: GDC-9545: A novel ER antagonist and clinical candidate that combines desirable mechanistic and pre-clinical DMPK attributes by Metcalfe, C, Ingalla, E, Blake, RA, Chang, J, Daemen, A, De Bruyn, T, Giltnane, JM, Guan, J, Hafner, M, Hartman, S, Kategaya, L, Kleinheinz, T, Liang, J, Mody, V, Nannini, M, Oeh, J, Ubhayakar, S, Wertz, I, Young, A, Zbieg, J, Zhou, W, Sampath, D, Friedman, LS, Wang, X

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ANNUAL MEETING PREVIEW

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Abstract SY23-03: Development and mechanistic characterization of USP7 deubiquitinase inhibitors by Wertz, Ingrid, Kategaya, Lorna, Lello, Paola Di, Rouge, Lionel, Pastor, Richard, Clark, Kevin R., Drummond, Jason, Kleinheinz, Tracy, Lin, Eva, Upton, John-Paul, Prakash, Sumit, Heideker, Johanna, McCleland, Mark, Ritorto, Maria Stella, Alessi, Dario R., Trost, Matthias, Bainbridge, Travis W., Kwok, Michael C., Ma, Taylur P., Stiffler, Zachary, Brasher, Bradley, Tang, Yinyan, Jaishanker, Priya, Hearn, Brian, Renslo, Adam R., Arkin, Michelle R., Cohen, Frederick, Yu, Kebing, Peale, Frank, Gnad, Florian, Chang, Matthew T., Klijn, Christiaan, Blackwood, Elizabeth, Martin, Scott E., Forrest, William F., Ernst, James A., Ndubaku, Chudi, Wang, Xiaojing, Beresini, Maureen H., Tsui, Vickie, Schwerdtfeger, Carsten, Blake, Robert A., Murray, Jeremy, Maurer, Till

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Abstract B23: Crucial deubiquitinases in cancer cell survival by Kategaya, Lorna, Cuellar, Trinna, Haley, Ben, Liu, Jinfeng, Tran, Andy, Cao, Yi, Stokoe, David, McCleland, Mark, Blackwood, Beth, Yee, Sharon, Drobnick, Joy, Drummond, Jake, Ernst, James, Kwok, Michael, Ly, Cuong, Pastor, Richard, Lello, Paola Di, Ndubaku, Chudi, Blake, Robert, Tsui, Vickie, Murray, Jeremy, Maurer, Till, Wertz, Ingrid

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Abstract 1864: Selective estrogen receptor degrader (SERD) activity in ESR1 mutant models by Zhou, Wei, Blake, Robert A., Nonomiya, Jim, Qian, Jing, Kategaya, Lorna, Wertz, Ingrid, Daemen, Anneleen, O'Brien, Thomas, Sensintaffar, John, Moon, Michael, Nannini, Michelle A., Oeh, Jason, Sampath, Deepak, Wang, Xiaojing, Smith, Nicholas, Brigham, Daniel, Joseph, James, Hager, Jeffrey H., Friedman, Lori S.

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The VOH centre in strontium oxide by Blake, W B J, Gitelson, H A, Wertz, J E

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Magnesium-25 Hyperfine Confirmation of the Localized-Ground-State Model of the V − Center in MgO by Halliburton, Larry E., Cowan, David L., Blake, W. B. J., Wertz, John E.

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