Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model by Lee, Michelle J, Hatton, Beryl A, Villavicencio, Elisabeth H, Khanna, Paritosh C, Friedman, Seth D, Ditzler, Sally, Pullar, Barbara, Robison, Keith, White, Kerry F, Tunkey, Chris, LeBlanc, Michael, Randolph-Habecker, Julie, Knoblaugh, Sue E, Hansen, Stacey, Richards, Andrew, Wainwright, Brandon J, McGovern, Karen, Olson, James M

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Endogenous IL-27 during toxoplasmosis limits early monocyte responses and their inflammatory activation by pathological T cells by Aldridge, Daniel L, Moodley, Devapregasan, Park, Jeongho, Phan, Anthony T, Rausch, Matthew, White, Kerry F, Ren, Yue, Golin, Karin, Radaelli, Enrico, Kedl, Ross, Holland, Pamela M, Hill, Jonathan, Hunter, Christopher A

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Impact of the Smoothened inhibitor, IPI-926, on smoothened ciliary localization and Hedgehog pathway activity by Peluso, Marisa O, Campbell, Veronica T, Harari, Joseph A, Tibbitts, Thomas T, Proctor, Jennifer L, Whitebread, Nigel, Conley, James M, White, Kerry F, Kutok, Jeffery L, Read, Margaret A, McGovern, Karen, Faia, Kerrie L

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IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma by Aghayev, Turan, Mazitova, Aleksandra M, Fang, Jennifer R, Peshkova, Iuliia O, Rausch, Matthew, Hung, Manhsin, White, Kerry F, Masia, Ricard, Titerina, Elizaveta K, Fatkhullina, Aliia R, Cousineau, Isabelle, Turcotte, Simon, Zhigarev, Dmitry, Marchenko, Anastasiia, Khoziainova, Svetlana, Makhov, Petr, Tan, Yin Fei, Kossenkov, Andrew V, Wiest, David L, Stagg, John, Wang, Xin Wei, Campbell, Kerry S, Dzutsev, Amiran K, Trinchieri, Giorgio, Hill, Jonathan A, Grivennikov, Sergei I, Koltsova, Ekaterina K

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Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27 by Składanowska, Katarzyna, Bloch, Yehudi, Strand, Jamie, White, Kerry F., Hua, Jing, Aldridge, Daniel, Welin, Martin, Logan, Derek T., Soete, Arne, Merceron, Romain, Murphy, Casey, Provost, Mathias, Bazan, J. Fernando, Hunter, Christopher A., Hill, Jonathan A., Savvides, Savvas N.

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Antiparasitic activities of novel, orally available fumagillin analogs by Arico-Muendel, Christopher, Centrella, Paolo A., Contonio, Brooke D., Morgan, Barry A., O’Donovan, Gary, Paradise, Christopher L., Skinner, Steven R., Sluboski, Barbara, Svendsen, Jennifer L., White, Kerry F., Debnath, Anjan, Gut, Jiri, Wilson, Nathan, McKerrow, James H., DeRisi, Joseph L., Rosenthal, Philip J., Chiang, Peter K.

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Carbamate Analogues of Fumagillin as Potent, Targeted Inhibitors of Methionine Aminopeptidase-2 by Arico-Muendel, Christopher C, Benjamin, Dennis R, Caiazzo, Teresa M, Centrella, Paolo A, Contonio, Brooke D, Cook, Charles M, Doyle, Elisabeth G, Hannig, Gerhard, Labenski, Matthew T, Searle, Lily L, Lind, Kenneth, Morgan, Barry A, Olson, Gary, Paradise, Christopher L, Self, Christopher, Skinner, Steven R, Sluboski, Barbara, Svendsen, Jennifer L, Thompson, Charles D, Westlin, William, White, Kerry F

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Orally Active Fumagillin Analogues: Transformations of a Reactive Warhead in the Gastric Environment by Arico-Muendel, Christopher C, Blanchette, Heather, Benjamin, Dennis R, Caiazzo, Teresa M, Centrella, Paolo A, DeLorey, Jennifer, Doyle, Elisabeth G, Johnson, Steven R, Labenski, Matthew T, Morgan, Barry A, O’Donovan, Gary, Sarjeant, Amy A, Skinner, Steven, Thompson, Charles D, Griffin, Sarah T, Westlin, William, White, Kerry F

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Abstract 4550: Increased IL-27 is associated with poor prognosis in renal cell carcinoma and supports use of SRF388, a first-in-class IL-27p28 blocking antibody, to counteract IL-2... by Rausch, Matthew, Hua, Jing, Moodley, Devapregasan, White, Kerry F., Walsh, Katherine H., Miller, Christine E., Tan, Gege, Lee, Benjamin H., Cousineau, Isabelle, Lattouf, Jean-Baptiste, Stagg, John, Palombella, Vito J., Holland, Pamela M., Hill, Jonathan A.

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Interleukin-27 signaling serves as an immunological checkpoint for innate cytotoxic cells to promote hepatocellular carcinoma by Aghayev, Turan, Mazitova, Aleksandra M., Fang, Jennifer R., Peshkova, Iuliia O., Rausch, Matthew, Hung, Manhsin, White, Kerry F., Masia, Ricard, Titerina, Elizaveta K., Fatkhullina, Aliia R., Cousineau, Isabelle, Turcotte, Simon, Zhigarev, Dmitry, Marchenko, Anastasiia, Khoziainova, Svetlana, Makhov, Petr, Tan, Yin Fei, Kossenkov, Andrew V., Wiest, David L., Stagg, John, Wang, Xin Wei, Campbell, Kerry S., Dzutsev, Amiran K., Trinchieri, Giorgio, Hill, Jonathan A., Grivennikov, Sergei I., Koltsova, Ekaterina K.

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Abstract 558: MERTK-specific antibodies that have therapeutic antitumor activity in mice disrupt the integrity of the retinal pigmented epithelium in cynomolgus monkeys by White, Kerry F., Rausch, Matthew, Hua, Jing, Walsh, Katherine H., Miller, Christine E., Wells, Christopher C., Moodley, Devapregasan, Lee, Benjamin H., Chappel, Scott C., Holland, Pamela M., Hill, Jonathan A.

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Abstract 1137: Determination of a recommended Phase 2 dose (RP2D) for SRF388, a first-in-class IL-27-blocking antibody, in patients with advanced solid tumors by Hill, Jonathan A., White, Kerry F., Rausch, Matthew, Chung, Jou-Ku, Patnaik, Amita, Naing, Aung, Morgensztern, Daniel, Mantia, Charlene M., Tannir, Nizar M., Smith, Lon S., Bowers, Beth, Alika, Alex, Harshman, Lauren C., Lee, Benjamin H.

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Impact of the Smoothened Inhibitor, IPI-926, on Smoothened Ciliary Localization and Hedgehog Pathway Activity: e90534 by Peluso, Marisa O, Campbell, Veronica T, Harari, Joseph A, Tibbitts, Thomas T, Proctor, Jennifer L, Whitebread, Nigel, Conley, James M, White, Kerry F, Kutok, Jeffery L, Read, Margaret A

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Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases by Lloyd-Price, Jason, Arze, Cesar, Ananthakrishnan, Ashwin N., Schirmer, Melanie, Avila-Pacheco, Julian, Poon, Tiffany W., Andrews, Elizabeth, Ajami, Nadim J., Bonham, Kevin S., Brislawn, Colin J., Casero, David, Courtney, Holly, Gonzalez, Antonio, Graeber, Thomas G., Hall, A. Brantley, Lake, Kathleen, Landers, Carol J., Mallick, Himel, Plichta, Damian R., Prasad, Mahadev, Rahnavard, Gholamali, Sauk, Jenny, Shungin, Dmitry, Vázquez-Baeza, Yoshiki, White, Richard A., Braun, Jonathan, Denson, Lee A., Jansson, Janet K., Knight, Rob, Kugathasan, Subra, McGovern, Dermot P. B., Petrosino, Joseph F., Stappenbeck, Thaddeus S., Winter, Harland S., Clish, Clary B., Franzosa, Eric A., Vlamakis, Hera, Xavier, Ramnik J., Huttenhower, Curtis

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Microclimate moderates plant responses to macroclimate warming by De Frenne, Pieter, Rodríguez-Sánchez, Francisco, Coomes, David Anthony, Baeten, Lander, Verstraeten, Gorik, Vellend, Mark, Bernhardt-Römermann, Markus, Brown, Carissa D., Brunet, Jörg, Cornelis, Johnny, Decocq, Guillaume M., Dierschke, Hartmut, Eriksson, Ove, Gilliam, Frank S., Hédl, Radim, Heinken, Thilo, Hermy, Martin, Hommel, Patrick, Jenkins, Michael A., Kelly, Daniel L., Kirby, Keith J., Mitchell, Fraser J. G., Naaf, Tobias, Newman, Miles, Peterken, George, Patřík, Petr, Schultz, Jan, Sonnier, Grégory, Van Calster, Hans, Waller, Donald M., Walther, Gian-Reto, White, Peter S., Woods, Kerry D., Wulf, Monika, Graae, Bente Jessen, Verheyen, Kris

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Attentional control abnormalities in posttraumatic stress disorder: Functional, behavioral, and structural correlates by Fani, Negar, King, Tricia Z., Clendinen, Cherita, Hardy, Raven A., Surapaneni, Sindhuja, Blair, James R., White, Stuart F., Powers, Abigail, Ely, Tim D., Jovanovic, Tanja, Ressler, Kerry J., Bradley, Bekh

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Effect of Phosphodiesterase-5 Inhibition on Exercise Capacity and Clinical Status in Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial by Redfield, Margaret M, Chen, Horng H, Borlaug, Barry A, Semigran, Marc J, Lee, Kerry L, Lewis, Gregory, LeWinter, Martin M, Rouleau, Jean L, Bull, David A, Mann, Douglas L, Deswal, Anita, Stevenson, Lynne W, Givertz, Michael M, Ofili, Elizabeth O, O’Connor, Christopher M, Felker, G. Michael, Goldsmith, Steven R, Bart, Bradley A, McNulty, Steven E, Ibarra, Jenny C, Lin, Grace, Oh, Jae K, Patel, Manesh R, Kim, Raymond J, Tracy, Russell P, Velazquez, Eric J, Anstrom, Kevin J, Hernandez, Adrian F, Mascette, Alice M, Braunwald, Eugene

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The Daniel K. Inouye Solar Telescope – Observatory Overview by Rimmele, Thomas R., Warner, Mark, Keil, Stephen L., Goode, Philip R., Knölker, Michael, Kuhn, Jeffrey R., Rosner, Robert R., McMullin, Joseph P., Casini, Roberto, Lin, Haosheng, Wöger, Friedrich, von der Lühe, Oskar, Tritschler, Alexandra, Davey, Alisdair, de Wijn, Alfred, Elmore, David F., Fehlmann, André, Harrington, David M., Jaeggli, Sarah A., Rast, Mark P., Schad, Thomas A., Schmidt, Wolfgang, Mathioudakis, Mihalis, Mickey, Donald L., Anan, Tetsu, Beck, Christian, Marshall, Heather K., Jeffers, Paul F., Oschmann, Jacobus M., Beard, Andrew, Berst, David C., Cowan, Bruce A., Craig, Simon C., Cross, Eric, Cummings, Bryan K., Donnelly, Colleen, de Vanssay, Jean-Benoit, Eigenbrot, Arthur D., Ferayorni, Andrew, Foster, Christopher, Galapon, Chriselle Ann, Gedrites, Christopher, Gonzales, Kerry, Goodrich, Bret D., Gregory, Brian S., Guzman, Stephanie S., Guzzo, Stephen, Hegwer, Steve, Hubbard, Robert P., Hubbard, John R., Johansson, Erik M., Johnson, Luke C., Liang, Chen, Liang, Mary, McQuillen, Isaac, Mayer, Christopher, Newman, Karl, Onodera, Brialyn, Phelps, LeEllen, Puentes, Myles M., Richards, Christopher, Rimmele, Lukas M., Sekulic, Predrag, Shimko, Stephan R., Simison, Brett E., Smith, Brett, Starman, Erik, Sueoka, Stacey R., Summers, Richard T., Szabo, Aimee, Szabo, Louis, Wampler, Stephen B., Williams, Timothy R., White, Charles

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Th2 responses are primed by skin dendritic cells with distinct transcriptional profiles by Connor, Lisa M, Tang, Shiau-Choot, Cognard, Emmanuelle, Ochiai, Sotaro, Hilligan, Kerry L, Old, Samuel I, Pellefigues, Christophe, White, Ruby F, Patel, Deepa, Smith, Adam Alexander T, Eccles, David A, Lamiable, Olivier, McConnell, Melanie J, Ronchese, Franca

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Cabotegravir for the prevention of HIV-1 in women: results from HPTN 084, a phase 3, randomised clinical trial by Delany-Moretlwe, Sinead, Hughes, James P, Bock, Peter, Hunidzarira, Portia, Kalonji, Dishiki, Kayange, Noel, Makhema, Joseph, Mandima, Patricia, Mathew, Carrie, Spooner, Elizabeth, Mpendo, Juliet, Mukwekwerere, Pamela, Mgodi, Nyaradzo, Ntege, Patricia Nahirya, Nakabiito, Clemensia, Nuwagaba-Biribonwoha, Harriet, Panchia, Ravindre, Singh, Nishanta, Farrior, Jennifer, Rose, Scott, Anderson, Peter L, Eshleman, Susan H, Marzinke, Mark A, Hendrix, Craig W, Beigel-Orme, Stephanie, Hosek, Sybil, Tolley, Elizabeth, Sista, Nirupama, Adeyeye, Adeola, Rooney, James F, Rinehart, Alex, Spreen, William R, Hanscom, Brett, Cohen, Myron S, Hosseinipour, Mina C, Asmelash, Aida, Sehurutshi, Alice, Baguma, Allan, Marais, Anita, Kawoozo, Barbarah, Malinga, Bongiwe Prudence, Mirembe, Brenda Gati, Okech, Brenda, Esterhuizen, Bryan, Murombedzi, Caroline, Gadama, Daphne, Hwengwere, Eldinah, Roos, Elizabeth, Magada, Elizabeth S, Shava, Emily, Piwowar-Manning, Estelle, Tahuringana, Eunice, Muhlanga, Felix GS, Conradie, Francesca, Angira, Frank, Nanyonjo, Gertrude, Kistnasami, Girisha, Naidoo, Ishana, Horak, Jaco, Jere, Jane, Moodley, Jeeva, Shin, Katie, Nel, Kerry, Bokoch, Kevin, Birungi, Lilian, Emel, Lynda, Monametsi, Maletsatsi, Sibanda, Marvelous, Chitukuta, Miria, Matimbira, Moleen, Sibisi, Ncamsile, Mudzonga, Netsai, Natureeba, Paul, Richardson, Paul, Musara, Petina, Macdonald, Pippa, Nkambule, Rejoice, Mosime, Repelang, White, Rhonda, Berhanu, Ribka, Ncube-Sihlongonyane, Ritha, Sekabira, Rogers, Siva, Samantha, Pillay, Saresha, Govender, Shamelle, Bamweyana, Sheiala, Innes, Steve, Dadabhai, Sufia, Samandari, Taraz, Tembo, Tchangani, Lungu Mabedi, Thandie, Chirenda, Thandiwe, Chidemo, Tinashe, Mudhune, Victor, Naidoo, Vikesh, Samaneka, Wadzanai, Agyei, Yaw, Musodza, Yeukai, Fourie, Yolandie, Gaffoor, Zakir

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