Absence of direct effects on the dopamine D2 receptor by mGluR2/3-selective receptor agonists LY 354,740 and LY 379,268 by Zysk, John R., Widzowski, Dan, Sygowski, Linda A., Knappenberger, Katharine S., Spear, Nathan, Elmore, Charles S., Dorff, Peter, Liu, Hongyan, Doherty, James, Chhajlani, Vijay

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Pharmacological Inhibition of PARP6 Triggers Multipolar Spindle Formation and Elicits Therapeutic Effects in Breast Cancer by Wang, Zebin, Grosskurth, Shaun E, Cheung, Tony, Petteruti, Philip, Zhang, Jingwen, Wang, Xin, Wang, Wenxian, Gharahdaghi, Farzin, Wu, Jiaquan, Su, Nancy, Howard, Ryan T, Mayo, Michele, Widzowski, Dan, Scott, David A, Johannes, Jeffrey W, Lamb, Michelle L, Lawson, Deborah, Dry, Jonathan R, Lyne, Paul D, Tate, Edward W, Zinda, Michael, Mikule, Keith, Fawell, Stephen E, Reimer, Corinne, Chen, Huawei

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Selective alpha 7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes by Sydserff, Simon, Sutton, E J, Song, Dekun, Quirk, Michael C, Maciag, Carla, Li, Chaoying, Jonak, Gerald, Gurley, David, Gordon, John C, Christian, Edward P, Doherty, James J, Hudzik, Tom, Johnson, Edwin, Mrzljak, Ladislav, Piser, Tim, Smagin, Gennady N, Wang, Yi, Widzowski, Dan, Smith, Jeffrey S

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Selective α7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes by Sydserff, Simon, Sutton, E.J., Song, Dekun, Quirk, Michael C., Maciag, Carla, Li, Chaoying, Jonak, Gerald, Gurley, David, Gordon, John C., Christian, Edward P., Doherty, James J., Hudzik, Tom, Johnson, Edwin, Mrzljak, Ladislav, Piser, Tim, Smagin, Gennady N., Wang, Yi, Widzowski, Dan, Smith, Jeffrey S.

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Abstract 3362: Miniaturized PBPK model improves pharmacodynamic characterization and physiological interpretability for compounds with profound hysteresis in tumor by Gibbons, Francis D., Widzowski, Dan, Shen, Minhui, Cheng, Jane, Drew, Lisa, Saeh, Jamal C., Ferguson, Douglas

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Abstract 919: AZD3463, a novel ALK/IGF1R inhibitor, overcomes multiple mechanisms of acquired resistance to crizotinib by Drew, Lisa, Cheng, Jane, Engelman, Jeffrey, Ferguson, Douglas, Katayama, Ryohei, McDermott, Brenda, Saeh, Jamal, Shaw, Alice, Shen, Minhui, Widzowski, Dan, Wu, Allan, Smith, Graeme

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Abstract 2461: Design and synthesis of AZD3463, a novel orally bioavailable dual ALK and IGF1R inhibitor, inhibits growth of crizotinib resistance cell lines with multiple mechanis... by Saeh, Jamal C., Yang, Bin, Pontz, Tim, Thakur, Kumar, Peng, Bo, Drew, Lisa, Rivard, Caroline, Widzowski, Dan, Cheng, Jane, Ferguson, Douglas, McDermott, Brenda, Shen, Minhui, McNulty, John, Katayama, Ryohei, Engleman, Jeffrey, Shaw, Alice, Russell, Daniel, Smith, Graeme

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D2 receptor occupancy in conscious rat brain is not significantly distinguished with [3H]-MNPA, [3H]-(+)-PHNO, and [3H]-raclopride by Peng, Teng, Zysk, John, Dorff, Peter, Elmore, Charles S., Ström, Peter, Malmquist, Jonas, Ding, Min, Tuke, David, Werkheiser, Jennifer, Widzowski, Dan, Mrzljak, Ladislav, Maier, Donna

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Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes by Sydserff, Simon, Sutton, E J, Song, Dekun, Quirk, Michael C, Maciag, Carla, Li, Chaoying, Jonak, Gerald, Gurley, David, Gordon, John C, Christian, Edward P, Doherty, James J, Hudzik, Tom, Johnson, Edwin, Mrzljak, Ladislav, Piser, Tim, Smagin, Gennady N, Wang, Yi, Widzowski, Dan, Smith, Jeffrey S

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