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The development of a CRISPR/Cas-mediated PD-1 knockout rat model to study idiosyncratic drug reactions including nevirapine-induced liver injury
by
Cho, Tiffany
,
Wierk, Antonia
,
Henderson, Jeffrey
,
Uetrecht, Jack
Published in
Drug metabolism and pharmacokinetics
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The development and characterization of a CRISPR/Cas9-mediated PD-1 functional knockout rat as a tool to study idiosyncratic drug reactions
by
Cho, Tiffany
,
Wierk, Antonia
,
Gertsenstein, Marina
,
Rodgers, Christopher
,
Uetrecht, Jack
,
Henderson, Jeffrey T
Published in
Toxicological sciences
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Drug Metabolism And Pharmacokinetics
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Toxicological Sciences
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Adverse Drug Reactions
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Amodiaquine
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Animal Models
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Idiosyncratic Drug Reactions
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Idiosyncratic Drug-Induced Liver Injury
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Immune Tolerance
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Life Sciences & Biomedicine
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Pd-1
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Science & Technology
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Toxicology
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