mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity by Cheng, Shih-Chin, Quintin, Jessica, Cramer, Robert A., Shepardson, Kelly M., Saeed, Sadia, Kumar, Vinod, Giamarellos-Bourboulis, Evangelos J., Martens, Joost H. A., Rao, Nagesha Appukudige, Aghajanirefah, Ali, Manjeri, Ganesh R., Li, Yang, Ifrim, Daniela C., Arts, Rob J. W., van der Meer, Brian M. J. W., Deen, Peter M. T., Logie, Colin, O’Neill, Luke A., Willems, Peter, van de Veerdonk, Frank L., van der Meer, Jos W. M., Ng, Aylwin, Joosten, Leo A. B., Wijmenga, Cisca, Stunnenberg, Hendrik G., Xavier, Ramnik J., Netea, Mihai G.

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Colorectal liver metastases: surgery versus thermal ablation (COLLISION) - a phase III single-blind prospective randomized controlled trial by Puijk, Robbert S, Ruarus, Alette H, Vroomen, Laurien G P H, van Tilborg, Aukje A J M, Scheffer, Hester J, Nielsen, Karin, de Jong, Marcus C, de Vries, Jan J J, Zonderhuis, Babs M, Eker, Hasan H, Kazemier, Geert, Verheul, Henk, van der Meijs, Bram B, van Dam, Laura, Sorgedrager, Natasha, Coupé, Veerle M H, van den Tol, Petrousjka M P, Meijerink, Martijn R

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Rare and low-frequency coding variants alter human adult height by Wood, Andrew R., Kjaer, Troels R., Lu, Yingchang, Thorleifsson, Gudmar, Turcot, Valérie, Young, Kristin L., Rivas, Manuel A., Abecasis, Goncalo, Aben, Katja K., Allin, Kristine H., Blüher, Matthias, Bots, Michiel L., Brilliant, Murray H., Carey, David J., Chambers, John C., Chasman, Daniel I., Chen, Yii-Der Ida, Chu, Audrey Y., Collins, Francis S., Cook, James P., de Groot, Mark C. H., de Mutsert, Renée, Ebeling, Tapani, Evangelou, Evangelos, Feng, Shuang, Ford, Ian, Fornage, Myriam, Gandin, Ilaria, Gordon, Scott D., Gustafsson, Stefan, Hattersley, Andrew T., Heid, Iris M., Helgeland, Øyvind, Hewitt, Alex W., Hovingh, G. Kees, Hoyng, Carel B., Huang, Paul L., Hveem, Kristian, Ikram, M. Arfan, Jansson, Jan-Håkan, Jarvik, Gail P., Jiang, Xuejuan, Jukema, J. Wouter, Kitajima, Hidetoshi, Kluivers, Kirsten B., Kontto, Jukka, Kooner, Jaspal S., Kriebel, Jennifer, Kuusisto, Johanna, Langenberg, Claudia, Lee, I-Te, Li, Huaixing, Lin, Honghuang, Lophatananon, Artitaya, Lyytikäinen, Leo-Pekka, Madden, Pamela A. F., Männistö, Satu, Mazul, Angela L., Metspalu, Andres, Mook-Kanamori, Dennis O., Morgan, Anna, Morris, Andrew P., Müller-Nurasyid, Martina, Nalls, Mike A., Nielsen, Sune F., Njølstad, Pål R., Palmer, Colin N. A., Pasterkamp, Gerard, Pedersen, Oluf, Perola, Markus, Perry, James A., Person, Thomas N., Salomaa, Veikko, Samani, Nilesh J., Sandow, Kevin, Schmidt, Marjanka K., Segura-Lepe, Marcelo P., Sim, Xueling, Small, Kerrin S., Southam, Lorraine, Steinthorsdottir, Valgerdur, Stumvoll, Michael, Tansey, Katherine E., Tardif, Jean-Claude, Taylor, Kent D., Thompson, Deborah J., Tyrer, Jonathan P., Uitterlinden, André G., van Schoor, Natasja M., Vozzi, Diego, Wang, Shuai, Wang, Yiqin, Wilson, James G., Young, Robin, Willer, Cristen J., Liu, Dajiang J., North, Kari E., Kutalik, Zoltán, Loos, Ruth J. F., Deloukas, Panos

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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology by Southam, Lorraine, Yin, Xianyong, Melloni, Giorgio E. M., Rayner, Nigel W., Bocher, Ozvan, Namba, Shinichi, Lee, Simon S. K., Petty, Lauren E., Schroeder, Philip, Kals, Mart, Zhang, Weihua, Graff, Mariaelisa, Lamri, Amel, Parra, Esteban J., Bielak, Lawrence F., Hai, Yang, Sofer, Tamar, Nousome, Darryl, Sun, Meng, Noordam, Raymond, Lim, Victor J. Y., Yanek, Lisa R., An, Ping, Tan, Jingyi, Canouil, Mickaël, Chee, Miao-Li, Chen, Shyh-Huei, Chen, Yuan-Tsong, Dimitrov, Latchezar, Doumatey, Ayo P., Du, Shufa, Eckardt, Kai-Uwe, Gerstein, Hertzel C., Han, Sohee, Herder, Christian, Howard, Annie-Green, Hsueh, Willa, Ichihara, Sahoko, Ikram, Mohammad Arfan, Jang, Hye-Mi, Jonas, Jost B., Kandeel, Fouad R., Kaur, Varinderpal, Lange, Leslie A., Lee, Myung-Shik, Leong, Aaron, Liu, Ching-Ti, Louie, Tin, Luo, Xi, Maeda, Shiro, Mansuri, Sohail Rafik, Nalls, Michael A., Nayak, Uma, Okada, Yukinori, Patil, Snehal, Prasad, Gauri, Roden, Michael, Rohde, Rebecca, Sandow, Kevin, Sankareswaran, Alagu, So, Wing Yee, Stilp, Adrienne M., Taylor, Kent D., Thorand, Barbara, Valladares-Salgado, Adan, Wheeler, Eleanor, Raffel, Leslie J., Igase, Michiya, Province, Michael A., Rotimi, Charles N., Peyser, Patricia A., Pankow, James S., Wilson, James G., Sheu, Wayne H. H., Mook-Kanamori, Dennis O., Collins, Francis S., Paré, Guillaume, Shu, Xiao-Ou, Dupuis, Josee, Kato, Norihiro, Laakso, Markku, Wareham, Nicholas J., Kim, Bong-Jo, Stefansson, Kari, Goodarzi, Mark O., Mohlke, Karen L., Florez, Jose C., Zöllner, Sebastian, Mägi, Reedik, van Heel, David A., Finer, Sarah, Ng, Maggie C. Y., Sim, Xueling, Below, Jennifer E., Chang, Kyong-Mi, Meigs, James B., Mahajan, Anubha, Vujkovic, Marijana, Voight, Benjamin F., Morris, Andrew P.

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Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion by Dhaese, S.A.M., Colin, P., Willems, H., Heffernan, A., Gadeyne, B., Van Vooren, S., Depuydt, P., Hoste, E., Stove, V., Verstraete, A.G., Lipman, J., Roberts, J.A., De Waele, J.J.

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Femoral vs Jugular Venous Catheterization and Risk of Nosocomial Events in Adults Requiring Acute Renal Replacement Therapy: A Randomized Controlled Trial by Parienti, Jean-Jacques, Thirion, Marina, Mégarbane, Bruno, Souweine, Bertrand, Ouchikhe, Abdelali, Polito, Andrea, Forel, Jean-Marie, Marqué, Sophie, Misset, Benoît, Airapetian, Norair, Daurel, Claire, Mira, Jean-Paul, Ramakers, Michel, du Cheyron, Damien, Le Coutour, Xavier, Daubin, Cédric, Charbonneau, Pierre, for Members of the Cathedia Study Group

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Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M... by Cheng, Tsing, Hitomi, Kiyotaka, van Vlijmen-Willems, Ivonne M J J, de Jongh, Gys J, Yamamoto, Kanae, Nishi, Koji, Watts, Colin, Reinheckel, Thomas, Schalkwijk, Joost, Zeeuwen, Patrick L J M

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Cost of exome analysis in patients with intellectual disability: a micro-costing study in a French setting by Soilly, A L, Robert-Viard, C, Besse, C, Bruel, A L, Gerard, B, Boland, A, Piton, A, Duffourd, Y, Muller, J, Poë, C, Jouan, T, El Doueiri, S, Faivre, L, Bacq-Daian, D, Isidor, B, Genevieve, D, Odent, S, Philip, N, Doco-Fenzy, M, Lacombe, D, Asensio, M L, Deleuze, J F, Binquet, C, Thauvin-Robinet, C, Lejeune, C

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Clinical, neuroradiological and genetic findings in pontocerebellar hypoplasia by NAMAVAR, Yasmin, BARTH, Peter G, BASEL-VANAGAITE, Lina, EGGENS, Veerle R. C, KRÄGELOH-MANN, Ingeborg, DE MEIRLEIR, Linda, KING, Mary, GRAHAM JR, John M, VON MOERS, Arpad, KNOERS, Nine, SZTRIHA, Laszlo, KORINTHENBERG, Rudolf, KASHER, Paul R, DOBYNS, William B, BAAS, Frank, TIEN POLL-THE, Bwee, VAN RUISSEN, Fred, BROCKMANN, Knut, BERNERT, Günther, WRITZL, Karin, VENTURA, Karen, CHENG, Edith Y, FERRIERO, Donna M

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Human Cytomegalovirus Infection of Epithelial Cells Increases SARS-CoV-2 Superinfection by Upregulating the ACE2 Receptor by Perera, Marianne R, Greenwood, Edward J D, Crozier, Thomas W M, Elder, Elizabeth G, Schmitt, Janika, Crump, Colin M, Lehner, Paul J, Wills, Mark R, Sinclair, John H

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Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension by Hadinnapola, Charaka, Bleda, Marta, Haimel, Matthias, Screaton, Nicholas, Swift, Andrew, Dorfmüller, Peter, Preston, Stephen D, Southwood, Mark, Hernandez-Sanchez, Jules, Martin, Jennifer, Treacy, Carmen, Yates, Katherine, Bogaard, Harm, Church, Colin, Coghlan, Gerry, Condliffe, Robin, Corris, Paul A, Gibbs, Simon, Girerd, Barbara, Holden, Simon, Humbert, Marc, Kiely, David G, Lawrie, Allan, Machado, Rajiv, MacKenzie Ross, Robert, Moledina, Shahin, Montani, David, Newnham, Michael, Peacock, Andrew, Pepke-Zaba, Joanna, Rayner-Matthews, Paula, Shamardina, Olga, Soubrier, Florent, Southgate, Laura, Suntharalingam, Jay, Toshner, Mark, Trembath, Richard, Vonk Noordegraaf, Anton, Wilkins, Martin R, Wort, Stephen J, Wharton, John, Gräf, Stefan, Morrell, Nicholas W

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Sialic acid catabolism by N-acetylneuraminate pyruvate lyase is essential for muscle function by Wen, Xiao-Yan, Tarailo-Graovac, Maja, Brand-Arzamendi, Koroboshka, Willems, Anke, Rakic, Bojana, Huijben, Karin, Da Silva, Afitz, Pan, Xuefang, El-Rass, Suzan, Ng, Robin, Selby, Katheryn, Philip, Anju Mary, Yun, Junghwa, Ye, X Cynthia, Ross, Colin J, Lehman, Anna M, Zijlstra, Fokje, Abu Bakar, N, Drögemöller, Britt, Moreland, Jacqueline, Wasserman, Wyeth W, Vallance, Hilary, van Scherpenzeel, Monique, Karbassi, Farhad, Hoskings, Martin, Engelke, Udo, de Brouwer, Arjan, Wevers, Ron A, Pshezhetsky, Alexey V, van Karnebeek, Clara Dm, Lefeber, Dirk J

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Athlome Project Consortium: a concerted effort to discover genomic and other "omic" markers of athletic performance by Pitsiladis, Yannis P, Tanaka, Masashi, Eynon, Nir, Bouchard, Claude, North, Kathryn N, Williams, Alun G, Collins, Malcolm, Moran, Colin N, Britton, Steven L, Fuku, Noriyuki, Ashley, Euan A, Klissouras, Vassilis, Lucia, Alejandro, Ahmetov, Ildus I, de Geus, Eco, Alsayrafi, Mohammed

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Vascular Access Sites for Acute Renal Replacement in Intensive Care Units by Dugué, Audrey E, Levesque, Stéphanie P, Fischer, Marc-Olivier, Souweine, Bertrand, Mira, Jean-Paul, Megarbane, Bruno, Daubin, Cédric, du Cheyron, Damien, Parienti, Jean-Jacques

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Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes—an international multicentre retrospective study by Wösten-van Asperen, Roelie M., la Roi-Teeuw, Hannah M., van Amstel, Rombout BE, Bos, Lieuwe DJ, Tissing, Wim JE, Jordan, Iolanda, Dohna-Schwake, Christian, Bottari, Gabriella, Pappachan, John, Crazzolara, Roman, Comoretto, Rosanna I., Mizia-Malarz, Agniezka, Moscatelli, Andrea, Sánchez-Martín, María, Willems, Jef, Rogerson, Colin M., Bennett, Tellen D., Luo, Yuan, Atreya, Mihir R., Faustino, E.Vincent S., Geva, Alon, Weiss, Scott L., Schlapbach, Luregn J., Sanchez-Pinto, L Nelson, Caballero, Marina, Margarit, Adriana, Campos, Roi, Möller, Paula, Serpe, Carmela, Amigoni, Angela, Damps, Maria, Montaguti, Alessia, Tardini, Giacomo, Bubeck-Wardenburg, Juliane, Farris, Reid Farris, Hall, Mark, Chong, Grace, Shah, Sareen, Khemani, Robinder, Stroup, Emily

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A nationwide assessment of hepatocellular adenoma resection: Indications and pathological discordance by Haring, Martijn P D, Elfrink, Arthur K E, Oudmaijer, Christiaan A J, Andel, Paul C M, Furumaya, Alicia, de Jong, Nenke, Willems, Colin J J M, Huits, Thijs, Sijmons, Julie M L, Belt, Eric J T, Bosscha, Koop, Consten, Esther C J, Coolsen, Mariëlle M E, van Duijvendijk, Peter, Erdmann, Joris I, Gobardhan, Paul, de Haas, Robbert J, van Heek, Tjarda, Lam, Hwai-Ding, Leclercq, Wouter K G, Liem, Mike S L, Marsman, Hendrik A, Patijn, Gijs A, Terkivatan, Türkan, Zonderhuis, Babs M, Molenaar, Izaak Quintus, Te Riele, Wouter W, Hagendoorn, Jeroen, Schaapherder, Alexander F M, IJzermans, Jan N M, Buis, Carlijn I, Klaase, Joost M, de Jong, Koert P, de Meijer, Vincent E

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De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures by Duarte, Sofia T., Charles, Perinne, Pfundt, Rolph, van Bokhoven, Hans, van Ravenswaaij-Arts, Conny, Morrell, Nicholas W., Thrasher, Adrian, Fletcher, Debra, Veltman, Marijke, Davis, John, Frary, Amy, Martin, Jennifer M., Collins, Janine, Favier, Remi, Hart, Daniel, Heemskerk, Johan W.M., Liesner, Ri, Mangles, Sarah, Roughley, Catherine, Tait, R. Campbell, Thachil, Jecko, Van Geet, Chris, De Vries, Minka, Warner, Timothy Q., Furnell, Abigail, Mapeta, Rutendo, Whitehorn, Deborah, Daugherty, Louise, Deevi, Sri V.V., Hu, Fengyuan, Matser, Vera, Megy, Karyn, Tuna, Salih, von Ziegenweldt, Julie, Haimel, Matthias, Richardson, Sylvia, Rankin, Stuart, Anderson, Julie, Stock, Sophie, Armstrong, Ruth, Bitner-Glindzicz, Maria, Brady, Angie, Clement, Emma, Firth, Helen, Flinter, Frances, French, Courtney, Holder, Muriel, Hurst, Jane, Josifova, Dragana, Krishnakumar, Deepa, Kurian, Manju A., Mehta, Sarju, Moore, Anthony, Rankin, Julia, Reid, Evan, Scott, Richard, Thomas, Ellen, Wassmer, Evangeline, Creaser-Myers, Amanda, Gall, Henning, Ghataorhe, Pavandeep K., Houweling, Arjan C., in’t Veld, Anna Huis, Ross, Rob V. Mackenzie, Rhodes, Christopher J., Soubrier, Florent, Treacy, Carmen M., Vonk Noordegraaf, Anton, Antrobus, Richard, Arumugakani, Gururaj, Bibi, Shahnaz, Devlin, Lisa, Ghurye, Rohit, Grigoriadou, Sofia, Harper, Lorraine, Herwadkar, Archana, Jolles, Stephen, Kumararatne, Dinakantha, Lorenzo, Lorena, Murng, Sai, Nejentsev, Sergey, Quinti, Isabella, Samarghitean, Crina, Savic, Sinisa, Yong, Patrick, Ancliff, Phil, Layton, Mark, Mead, Adam, Roy, Noémi, Chambers, Jenny, Estiu, Cecelia, Simpson, Michael, Emmerson, Ingrid, McCarthy, Mark, Van Zuydam, Natalie, Afzal, Maryam, Colby, Elizabeth, Boycott, Kym M., Majewski, Jacek, Dyment, David

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Continuous Renal Replacement Therapy May Increase the Risk of Catheter Infection by Parienti, Jean-Jacques, Dugué, Audrey E, Daurel, Claire, Mira, Jean-Paul, Mégarbane, Bruno, Mermel, Leonard A, Daubin, Cédric, du Cheyron, Damien

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Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes—an international multicentre retrospective studyResearch in context by Roelie M. Wösten-van Asperen, Hannah M. la Roi-Teeuw, Rombout BE. van Amstel, Lieuwe DJ. Bos, Wim JE. Tissing, Iolanda Jordan, Christian Dohna-Schwake, Gabriella Bottari, John Pappachan, Roman Crazzolara, Rosanna I. Comoretto, Agniezka Mizia-Malarz, Andrea Moscatelli, María Sánchez-Martín, Jef Willems, Colin M. Rogerson, Tellen D. Bennett, Yuan Luo, Mihir R. Atreya, E.Vincent S. Faustino, Alon Geva, Scott L. Weiss, Luregn J. Schlapbach, L Nelson Sanchez-Pinto, Marina Caballero, Adriana Margarit, Roi Campos, Paula Möller, Carmela Serpe, Angela Amigoni, Maria Damps, Alessia Montaguti, Giacomo Tardini, Juliane Bubeck-Wardenburg, Reid Farris Farris, Mark Hall, Grace Chong, Sareen Shah, Robinder Khemani, Emily Stroup

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Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization by Willems, Sara M, Ng, Natasha H J, Fernandez, Juan, Fine, Rebecca S, Wheeler, Eleanor, Wessel, Jennifer, Kitajima, Hidetoshi, Marenne, Gaelle, Sim, Xueling, Yaghootkar, Hanieh, Wang, Shuai, Chen, Sai, Chen, Yuning, Chen, Yii-Der Ida, Grarup, Niels, Li-Gao, Ruifang, Varga, Tibor V, Asimit, Jennifer L, Feng, Shuang, Strawbridge, Rona J, Kleinbrink, Erica L, Ahluwalia, Tarunveer S, An, Ping, Appel, Emil V, Arking, Dan E, Auvinen, Juha, Bielak, Lawrence F, Bihlmeyer, Nathan A, Bork-Jensen, Jette, Brody, Jennifer A, Campbell, Archie, Chu, Audrey Y, Davies, Gail, Demirkan, Ayse, Floyd, James S, Giulianini, Franco, Guo, Xiuqing, Gustafsson, Stefan, Jackson, Anne U, Jakobsdottir, Johanna, Järvelin, Marjo-Riitta, Jensen, Richard A, Kanoni, Stavroula, Keinanen-Kiukaanniemi, Sirkka, Li, Man, Lu, Yingchang, Luan, Jian'an, Manning, Alisa K, Marten, Jonathan, Meidtner, Karina, Mook-Kanamori, Dennis O, Muka, Taulant, Pistis, Giorgio, Prins, Bram, Rice, Kenneth M, Sanna, Serena, Smith, Albert Vernon, Smith, Jennifer A, Southam, Lorraine, Stringham, Heather M, Tragante, Vinicius, van der Laan, Sander W, Warren, Helen R, Yao, Jie, Yiorkas, Andrianos M, Zhang, Weihua, Zhao, Wei, Graff, Mariaelisa, Highland, Heather M, Justice, Anne E, Marouli, Eirini, Medina-Gomez, Carolina, Afaq, Saima, Alhejily, Wesam A, Amin, Najaf, Asselbergs, Folkert W, Bonnycastle, Lori L, Bots, Michiel L, Brandslund, Ivan, Chen, Ji, Danesh, John, de Mutsert, Renée, Dehghan, Abbas, Ebeling, Tapani, Elliott, Paul, Farmaki, Aliki-Eleni, Faul, Jessica D, Franks, Paul W, Franks, Steve, Fritsche, Andreas, Gjesing, Anette P, Goodarzi, Mark O, Gudnason, Vilmundur, Hallmans, Göran, Harris, Tamara B, Herzig, Karl-Heinz, Hivert, Marie-France, Jørgensen, Torben, Jørgensen, Marit E, Jousilahti, Pekka

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