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Abstract PR011: Discovery of VVD-065, a first-in-class allosteric molecular glue of the Keap1-Cul3 E3-ligase complex for the treatment of NRF2-activated cancers
by
Roy, Nil
,
Wyseure, Tine
,
Lo, I-Chung
,
Inloes, Jordon
,
Snead, Aaron
,
Bernard, Steffen
,
Metzger, Justine
,
Pollock, Jonathan
,
Grabow, Stephanie
,
Eissler, Christie
,
Williams, Melaminah
,
Jacinto, Sarah
,
Simon, Gabe
,
Kinsella, Todd
,
Weinstein, David
,
Patricelli, Matt
Published in
Molecular cancer therapeutics
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Abstract C126: Translational pharmacokinetic/pharmacodynamic (PK/PD) modeling of novel covalent Kelch-like ECH-associated protein 1 (KEAP1) activators
by
Housand, Conrad
,
Roy, Nil
,
Wyseure, Tine
,
Eissler, Christie
,
Metzger, Justine
,
Bairlein, Michaela
,
O'Brien, Julie
,
Williams, Melaminah
,
Contreras, Victor
,
Garrido, Marine
,
Kinsella, Todd
,
Goldberg, Jenna
,
Patricelli, Matt
,
Morcos, Peter N.
Published in
Molecular cancer therapeutics
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Molecular Cancer Therapeutics
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